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1.
Journal of Pediatrics Review ; 10(4):277-286, 2022.
Article in English | Web of Science | ID: covidwho-2310099

ABSTRACT

Background: Considering the chronic immunosuppression in Inflammatory Bowel Disease (IBD) patients, it is necessary to evaluate the course of COVID-19 in these patients. Studies have shown various results in adult IBD patients. This study aimed to find out the course of this infection in pediatric IBD patients. Methods: This was a systematic review study according to the PRISMA 2020 guideline. International databases including Scopus, PubMed, and the Web of Science were searched with a combination of "COVID-19" AND "IBD" or synonyms until October 16, 2021. Studies that have reported the outcomes of COVID-19 infection in patients less than 19 years of age were selected. Name of author, country, study duration and type, IBD type and drugs, and COVID-19 outcomes were extracted. Results: From the initially retrieved 2215 articles, finally 16 articles were eligible. Data from 1040 pediatric IBD patients were reported. Twenty-four patients were hospitalized, 5 developed patients multisystem inflammatory syndrome in children, and others had a mild disease course and were outpatient. Steroid use, severe IBD activity, and comorbidities were shown to increase risk of hospitalization and disease severity. Conclusions: COVID-19 is a benign and self-limited disease in pediatric IBD patients. Comorbidities, steroid use, and severe IBD activity affect the outcomes.

2.
Frontiers in Optics, FiO 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2229803

ABSTRACT

FRET is ascribed to the spectral overlapping of upconversion luminescence and the absorption of AuNPs. This experiment enables early-stage coronavirus detection. The results show a sensitivity of 100 fM for the detection of COVID-19 DNA. © 2022 The Author(s)

3.
Health Scope ; 12(1), 2023.
Article in English | Web of Science | ID: covidwho-2226105

ABSTRACT

Background: Job burnout is a prolonged response to chronic emotional and interpersonal stressorsObjectives: This study aimed to evaluate job burnout and identify its effective predictors among health sector employees during the COVID-19 pandemic.Methods: This cross-sectional study encompassed 1898 employees of the Shahid Beheshti University of Medical Sciences in the sum-mer of 2020. Logistic regression was used to determine factors associated with job burnout. The required data were collected elec-tronically using the Maslach Burnout Inventory (MBI) and analyzed with SPSS software version 26 and R4.0.2 software.Results: Of 1898 participants, 74.3% were female. Composite job burnout (CJB), emotional exhaustion (EE), and depersonalization (DP) were the most common at low levels, whereas reduced personal accomplishment (RPA) was the most frequent at moderate levels. In this regard, factors such as female gender, age groups of 40 -49 and >= 50 years, and exposure to COVID-19 were the main independent risk factors for job burnout.Conclusions: Reduced personal accomplishment was moderate despite relatively low levels of job burnout, EE, and DP. Accordingly, effective interventions are suggested to improve different aspects of the work-life with an emphasis on critical situations. Moreover, regarding the significant relationship between job burnout with gender, age, and exposure to COVID-19, it is recommended to in-crease the employees' knowledge about job burnout.

4.
Frontiers in Optics, FiO 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2218621

ABSTRACT

FRET is ascribed to the spectral overlapping of upconversion luminescence and the absorption of AuNPs. This experiment enables early-stage coronavirus detection. The results show a sensitivity of 100 fM for the detection of COVID-19 DNA. © 2022 The Author(s)

5.
Journal of Iranian Medical Council ; 5(1):118-124, 2022.
Article in English | Scopus | ID: covidwho-2025960

ABSTRACT

Background: Vaccination is likely to be the final solution to stop the COVID-19 pandemic which has been considered as a global public health emergency. Influenza and coronavirus have previously demonstrated antigenic cross-reactivity. Methods: This cross-sectional study was aimed to evaluate the transmission rate and the severity of coronavirus infection among health care workers with history of previous influenza vaccination. Subjects of the study were asked about their demographics, influenza vaccination history prior to pandemic, infection with COVID-19, and the severity indicators of the disease. Results: Influenza vaccination has correlation neither with the prevalence of COVID-19 infection rate nor with the severity of the disease process among those who received flu vaccines and those who were not vaccinated. Vaccinated and unvaccinated subjects were equal in terms of sex, age, and comorbidities. Asthma has not been demonstrated to contribute to the severity of the disease. Conclusion: Influenza vaccination regardless of the evidence on its antigenic cross reactivity with coronavirus, is not associated with lesser involvement by or any contribution to the severity of the 2019 novel SARS-COV2 disease. Copyright 2022, Journal of Iranian Medical Council. All rights reserved.

6.
Frontiers in Optics and Photonics ; : 241-252, 2021.
Article in English | Scopus | ID: covidwho-1674037

ABSTRACT

Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on "Meet the Press" that "[T]he U.S. needs a 'breakthrough' in coronavirus testing to help screen Americans and get a more accurate picture of the virus' spread." We have been involved with biopathogen detection since the 2001 anthrax attacks and were the first to detect anthrax in real-time. A variation on the laser spectroscopic techniques we developed for the rapid detection of anthrax can be applied to detect the Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2 virus). In addition to detecting a single virus, this technique allows us to read its surface protein structure. In particular, we have been conducting research based on a variety of quantum optical approaches aimed at improving our ability to detect Corona Virus Disease-2019 (COVID-19) viral infection. Indeed, the detection of a small concentration of antibodies, after an infection has passed, is a challenging problem. Likewise, the early detection of disease, even before a detectible antibody population has been established, is very important. Our team is researching both aspects of this problem. The paper is written to stimulate the interest ofboth physical and biological scientists in this important problem. It is thus written as a combination of tutorial (review) and future work (preview). We join Prof. Federico Capasso and Editor Dennis Couwenberg in expressing our appreciation to all those working so heroically on all aspects of the COVTD-19 problem. And we thank Drs. Capasso and Couwenberg for their invitation to write this paper. © 2021 Walter de Gruyter GmbH, Berlin/Boston. All rights reserved.

7.
Nanophotonics ; 2020.
Article in English | Scopus | ID: covidwho-892404

ABSTRACT

Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on "Meet the Press"that "[T]he U.S. needs a 'breakthrough' in coronavirus testing to help screen Americans and get a more accurate picture of the virus' spread."We have been involved with biopathogen detection since the 2001 anthrax attacks and were the first to detect anthrax in real-time. A variation on the laser spectroscopic techniques we developed for the rapid detection of anthrax can be applied to detect the Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2 virus). In addition to detecting a single virus, this technique allows us to read its surface protein structure. In particular, we have been conducting research based on a variety of quantum optical approaches aimed at improving our ability to detect Corona Virus Disease-2019 (COVID-19) viral infection. Indeed, the detection of a small concentration of antibodies, after an infection has passed, is a challenging problem. Likewise, the early detection of disease, even before a detectible antibody population has been established, is very important. Our team is researching both aspects of this problem. The paper is written to stimulate the interest of both physical and biological scientists in this important problem. It is thus written as a combination of tutorial (review) and future work (preview). We join Prof. Federico Capasso and Editor Dennis Couwenberg in expressing our appreciation to all those working so heroically on all aspects of the COVID-19 problem. And we thank Drs. Capasso and Couwenberg for their invitation to write this paper. © 2020 Navid Rajil et al., published by De Gruyter, Berlin/Boston 2020.

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