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1.
Archives of Disease in Childhood ; 107(Supplement 2):A207, 2022.
Article in English | EMBASE | ID: covidwho-2064029

ABSTRACT

Aims Paediatric populations are generally considered to be at a lower risk of mortality from COVID-19 infection compared with adult populations. Regardless, a notable number of deaths from COVID-19 have been reported in paediatric populations. Therefore, the purpose of our work was to conduct a scoping review of the literature to assess the risk factors for COVID-19 mortality among paediatric populations. Methods Our review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR). Searches were performed in PubMed, Scopus, medRxiv, and WHO Coronavirus Database. There were no restrictions placed for searches based on date. Papers that were written in English, included at least one paediatric death from COVID-19, and described at least one risk factor for the death and/or clinical presentation of the child(ren) were eligible for inclusion. The paediatric population was defined as children aged 18 years and younger. Results Searches generated a total of 5828 papers and, of those, 75 were eligible for inclusion. There was a pooled total of 876 paediatric deaths. Significant risk factors for paediatric mortality included having co-infection of other pathogens, and at least one comorbidity;the comorbidities most frequently associated with mortality were malignancies, heart conditions, kidney disease, and genetic disorders such as Down Syndrome. The development of Paediatric Multisystem Inflammatory Syndrome (PMIS) was also consistently demonstrated to be a risk factor. Common clinical complications associated with paediatric COVID-19 infection resulting in mortality were sepsis, acute respiratory distress syndrome (ARDS), and acute kidney injury (AKI). Conclusion Our review has highlighted prominent risk factors for mortality from COVID-19 amongst paediatric populations. It is vital to consider the risk factors in order to assist prognostication and clinical decisions for severe paediatric infections of COVID-19. Our findings also highlight the importance of COVID-19 vaccination in paediatric populations.

2.
Chest ; 162(4):A1485-A1486, 2022.
Article in English | EMBASE | ID: covidwho-2060829

ABSTRACT

SESSION TITLE: Actionable Improvements in Safety and Quality SESSION TYPE: Rapid Fire Original Inv PRESENTED ON: 10/17/2022 12:15 pm - 1:15 pm PURPOSE: The overall mortality rate for patients ‘transfered’ to the medical intensive care units is thought to be significantly higher than the mortality rate amongst those admitted directly. (1) It has also been suggested that uninsured critically ill patients have a higher probability of being ‘transferred’ to other hospitals as well as a higher mortality rate. (2, 3) We aim to determine whether insurance coverage impacts the transfer of critically ill patients. METHODS: This study was conducted at a quaternary care hospital which is also a regional transfer center. We accessed the public data for the year 2020 through our institutions Transfer Center Dashboard, System Analytics. The two aspects of transferred patients we focused upon were: 1) Hospital service (subspecialty care required) and 2) Financial class. Major subspecialties included in the study were: Pulmonology, Internal Medicine, Neurosurgery, Cardiology, and Neurology. Our study was a patient safety project, hence it qualified for IRB exemption. We classified the percentage of transfers as ‘Accepted’, ‘Declined’, or ‘Canceled’;and determined the insurance status of the patient. RESULTS: We found a total of 3552 patients transfers were initiated. 31.9% (1136) transfer patients were accepted, 46.79% (1662) transfers were declined, and 21.23% (754) were canceled due to reasons including unsafe transfer, acceptance at other institutions, or death prior to transfer. Major categories for transfers were Pulmonology (16.1%), other Internal Medicine related diseases (15.3%), and Neurosurgery (11.8%) were the subspecialties with the highest rate of transfers. In terms of financial class, we determined that 44.81% (n=509) of the ICU transfers had no insurance, 27.81% (n=316) had Medicare support, and 17.81% (n=202) had managed care through a health maintenance organization (HMO);the remaining 9.59% had other insurance plans. We used a binomial test to determine the probability of a transfer under no insurance (p) with the formula p + q=1, across the total number of transfer requests (n). K was the number of actual transfers that occurred. Total transfer requests were n=3552, actual transfers were k=1136 and transfers without insurance were 509/44.8%, converted into p=0.45 with a resulting q of 0.55.For z-test, we used the formula z = ((K - np) +- 0.5) / √npq = 15.58. Our one-tailed probability of exactly, or fewer than, 1136(K) out of 3552(n) was p <.000001. Our study was limited because of the COVID-19 pandemic occurring in the same year. CONCLUSIONS: Based on our results, we conclude that the ‘uninsured’ patients are more susceptible to getting transferred to other institutions. CLINICAL IMPLICATIONS: Critically ill ‘uninsured’ patients are selctively subjected to be transfered to other hospitals for higher level of care. These transfers may have significant health implications thereby resulting in higher morbidity and mortality in unisured populations. DISCLOSURES: No relevant relationships by Joodi Akhtar No relevant relationships by Sahar Fatima Advisory Committee Member relationship with Astra Zeneca Please note: 24 months Added 03/16/2022 by FAISAL MASUD, value=Honoraria Advisory Committee Member relationship with Teleflex Please note: 12 months Added 03/16/2022 by FAISAL MASUD, value=Consulting fee Advisory Committee Member relationship with La Jolla Please note: 12 months Added 03/16/2022 by FAISAL MASUD, value=Consulting fee No relevant relationships by Iqbal Ratnani No relevant relationships by Salim Surani No relevant relationships by Anza Zahid

3.
Rawal Medical Journal ; 47(3):523-526, 2022.
Article in English | EMBASE | ID: covidwho-2044379

ABSTRACT

Objective: To evaluate the coagulation profile in COVID-19 patients and to correlate disease severity with the coagulation parameters. Methodology: This retrospective study was conducted at Pathology and medicine departments, FMH College of Medicine and Dentistry. It included 101 confirmed cases of COVID-19 disease of both genders between 17 and 75-year age. Coagulation profile was compared between survivor and non-survivor groups. Results: Out of 101 patients, 93 (92.1%) patients were in the survivor group and eight (7.8%) in the non-survivor group. Mean APTT (p = 0.02) in non-survivor group showed relatively higher values than survivor group. Mean D-Dimers (p = 0.007) in non-survivors showed a significantly raised values. However other parameters of coagulation like Platelets, MPV, PT and INR showed no significant association statistically. Conclusion: High D-dimers and prolonged APTT were associated with mortality in COVID-19 Patients.

4.
Bangladesh Journal of Medical Science ; 21(4):883-892, 2022.
Article in English | EMBASE | ID: covidwho-2043411

ABSTRACT

Respiratory illness is one of the most important public health problems in many countries worldwide. Even though most of the ailments are treatable with normal care, respiratory-related mortality continues to increase year after year. The global situation is deteriorating as a result of the COVID-19 epidemic. Numerous Unani formulations are beneficial against a variety of respiratory disorders, but they must be clinically researched before they can obtain widespread acceptance in the modern world. At the moment, no antiviral medication is either available for each respiratory disease or is costly and not easy to use in pandemics like COVID-19 on large scale, although Unani medicines may be considered an option. Khamira Banafsha (KB) is a semi-solid blend of three dried flowers, Viola odorata L., Borago officinalis L., and Rosa damascena Mill and the distillate of Rosa damascena, and sugar. The components in this formulation are well-known and frequently utilized in the treatment of respiratory problems.The formulation has been used to treat a wide range of illnesses for decades. This review will discuss the pharmacology, ethnopharmacology, and repurposing of KB as an adjuvant or symptomatic treatment for Covid-19 illness.The chemical composition of the ingredients may be evaluated In-silico to identify their eligibility for Covid-19 disease symptomatic management.

5.
British Journal of Surgery ; 109:vi36, 2022.
Article in English | EMBASE | ID: covidwho-2042530

ABSTRACT

Aim: The COVID-19 pandemic has adversely affected medical education and training programmes worldwide. This study aims to assess the impact of COVID-19 pandemic on surgical education and training in a low-income country. Method: This cross-sectional study was conducted in Allied hospitals of Rawalpindi Medical University, Rawalpindi, Pakistan, from June 2021 to July 2021. A structured questionnaire designed by the researchers was distributed to all surgery departments, and surgical residents who consented to participate in this study were included. Data was analyzed using IBM SPSS v25. Results: A total of 152 residents participated in this study, of which 53 (34.9%) were in general surgery and 99 (65.1%) in various surgical allied specialties. A large number of respondents reported a severe to complete reduction of elective surgical procedures (78, 51.3%), outpatient clinical activity (54, 35.6%) and academic sessions (86, 56.6%). A significantly higher number of general surgery residents (52.8%) reported increase in emergency surgical procedures as compared to surgical allied specialties (35.4%) (P=0.037). Majority of the respondents believed that loss of surgical training opportunities had a negative impact on their training and job performance (127, 83.6% and 130, 85.5%, respectively) with 43 (28.3%) residents suggesting an extension in training program. 137 (90.1%) residents reported increased stress and anxiety levels with the number of surgical allied residents significantly higher than general surgery residents (P=0.031). 125 (82.2%) respondents claimed that fear of contracting the virus affected proper patient evaluation. Conclusions: COVID-19 pandemic has severely impacted the training and psychological wellbeing of surgical residents and drastically affected patient evaluation.

6.
Indian Journal of Psychiatry ; 64, 2022.
Article in English | Web of Science | ID: covidwho-2003363
7.
Crystals ; 12(7):972, 2022.
Article in English | MDPI | ID: covidwho-1928497

ABSTRACT

The use of transition metal complexes as therapeutic compounds has become more and more pronounced. These complexes offer a great diversity of uses in their medicinal applications. Electronic cigarettes (ECs) are an electronic nicotine delivery system that contain aerosol (ECR). The ligation behavior of prednisolone, which is a synthetic steroid that is used to treat allergic diseases and asthma arthritis, and its Zn (II) metal complex were studied and characterized based on elemental analysis, molar conductance, Fourier-transform infrared (FT-IR) spectra, electronic spectra, XRD, scanning electron microscopy (SEM), energy dispersive x-ray (EDX), and transmission electron microscopy (TEM). The FT-IR spectral data revealed that PRD acts as a mono-dentate ligand via oxygen atoms of the carbonyl group. Electronic and FT-IR data revealed that the PRD/Zn (II) metal complexes have square planner geometry. Artemisinin (ART) is the active main constituent of Artemisia annua extract, and it has been demonstrated to exert an excellent antimalarial effect. The experiment was performed on 40 male mice that were divided into the following 7 groups: Control, EC group, PRD/Zn, ART, EC plus PRD/Zn, EC plus ART, and PRD plus combination of PRD/Zn and ART. Serum CRP, IL-6, and antioxidants biomarkers were determined. Pulmonary tissue histology was evaluated. When in combination with Zn administration, PRD showed potent protective effects against pulmonary biochemical alterations induced by ECR and suppressed severe oxidative stress and pulmonary structure alterations. Additionally, PRD/Zn combined with ART prevented any stress on the pulmonary tissues via antioxidant regulation, reducing inflammatory markers CRP and Il-6 and improving antioxidant enzymatic levels more than either PRD or ART alone. Therefore, PRD/Zn combined with ART produced a synergistic effect against any sort of oxidative stress and also improved the histological structure of the lung tissues. These findings are of great importance for saving pulmonary function, especially during pandemic diseases, such as during the COVID-19 pandemic.

8.
American Journal of Respiratory and Critical Care Medicine ; 205(1), 2022.
Article in English | EMBASE | ID: covidwho-1927738

ABSTRACT

Background - Among all the specialties, Critical Care Medicine physicians have reported the highest rate of burnout in the year 2021[Medscape National Physician Burnout & Suicide Report 2021]. Likewise, all Intensive Care Unit (ICU) staff such as nurses, respiratory therapists and patient care assistants as frontline workers have been experiencing stress during g the past 18 months of the COVID-19 pandemic. Here we present an initiative of Center for Performing Arts (CPAM) department at a tertiary care academic medical center to help reduce fatigue and burnout among ICU staff through splatter painting. Methods - This study was conducted in a 36-bed Cardiovascular ICU at a tertiary care hospital. Permission was obtained from the relative departments for the use of data. CPAM planned a 3-day splatter tent event in the ICU. This event was mainly for the ICU staff but was open to all the hospital staff. The event was advertised using colorful flyers. Each participant was led to a quiet room where they would drape, pick their favorite music selection, and color prop. Participants were then left alone to unwind and release all the feels in the form of creating art and could stay as long as they wanted. Pre- and post-completion surveys were recorded and, data was analyzed. Results - A total of 49 staff participated. 32 out of 49 participants returned their surveys. Overwhelmingly majority of the comments were positive. The most popular music genre was rap/hip hop. Average stress levels 1(low) to 5(high) were 4.19 - before to 2.56 - after. The average score (1-least) to 5-most) for if the intervention helped with compassion fatigue (F) and mental exhaustion (ME) was 4.22 and 4.44 respectively. The average score for if the intervention helped them feel more engaged at work (EW) and instilled positive attitude (PA) towards organization was 4.34 and 4.77 respectively. We did Pearson's correlation for the four components of the activity i.e., F, ME, EW and PA. Our R was strongly positive with value of 0.9913, using formula r = Σ((X - My)(Y - Mx)) / √((SSx)(SSy)). We also cross checked meta-numerics. Our value of R2 (the coefficient of determination) was 0.9827. Our P-Value was .001199, with significance at p < .05. Conclusions - The level of burnout amongst healthcare workers is at a critical level globally. Healthcare administrations need to find ways to mitigate feelings of burnout and fatigue amongst staff. (Figure Presented).

9.
Neurology ; 98(18 SUPPL), 2022.
Article in English | EMBASE | ID: covidwho-1925215

ABSTRACT

Objective: To study the cause of prolonged altered sensorium following cessation of sedation in mechanically ventilated patients Background: Patients with severe COVID-19 are at risk of thrombotic complications such as deep vein thrombosis, pulmonary thromboembolism, myocardial infarction and stroke. The incidence of strokes following COVID-19 is reported to be around 1.2%. There has been an increased incidence of large vessel strokes, especially, in young patients without any known risk factors in patients with COVID-19. Design/Methods: We report four cases of stroke diagnosed following neuroimaging in patients with severe COVID-19 Acute respiratory distress syndrome (ARDS). Results: All the patients were receiving supportive treatment and mechanical ventilation at the time of diagnosis of stroke. All patients received sedation and paralytics during mechanical ventilation. Poor response to stimulation and inability to wake up after sedation had worn off prompted neuroimaging in these patients, which revealed stroke. Incidentally, all these patients had hypernatremia at the time of diagnosis of stroke. Conclusions: This case series suggests that stroke should be considered in all COVID-19 patients who continue to have altered sensorium even after the cessation of sedation.

10.
Indian Journal of Environmental Protection ; 42(4):424-431, 2022.
Article in English | Scopus | ID: covidwho-1918761

ABSTRACT

SARS-CoV-2 (Covid-19) has taken over the world. The deadly virus causes serious respiratory infections in humans. A number of research are ongoing to contain the spread of the virus. The aim of this review is to assess the impact of air pollution and environmental factors which may influence the transmission of the disease. The utilization of indigenous natural sources as remedial measures has also been explored. The studies cited in the review have been sourced from journals, books and digital media reports. The research papers indexed in databases such as PUBMED, SCOPUS and MEDLINE, etc., have been included. Evidence has suggested that the spike in air pollution may exacerbate the number of infections and the improved air quality during the lockdown period may influence the faster recovery rate. Environmental factors, like temperature, humidity and air pollution have been explored as contributing factors for the facilitated spread of the infection, or atleast in making people more vulnerable to it which makes it an issue of considerable attention in developing countries, like India, due to the high air pollution levels in megacities. © 2022 - Kalpana Corporation.

11.
International Journal of Educational Management ; 2022.
Article in English | Scopus | ID: covidwho-1901358

ABSTRACT

Purpose: This research investigates the relationship between e-learning service quality dimensions, student e-learning satisfaction, commitment and behaviour towards finance courses in higher education institutes of Pakistan. Design/methodology/approach: Due to specific study objectives, the authors gathered sample data of 359 university students who were enrolled in the traditional learning system and shifted to the e-learning environment. The study employed partial least squares-structural equation modelling (PLS-SEM) based approach using Smart PLS version 3.0. Findings: The results indicated that out of four e-learning service quality dimensions, three dimensions (system quality, course material and instructor quality, information technology (IT) and support service quality) positively impacted student e-learning satisfaction. The other dimension of e-learning service quality (course website quality) showed a positive but insignificant effect on e-learning satisfaction. Additionally, e-learning satisfaction was positively related to e-learning commitment, which, in turn, has a positive and significant influence on student e-learning behaviour towards finance courses. Originality/value: Overall, the study’s findings provide useful policy implications for higher education institutes, particularly in the coronavirus disease 2019 (COVID-19) pandemic. © 2022, Emerald Publishing Limited.

12.
Pakistan Journal of Medical and Health Sciences ; 16(5):64-66, 2022.
Article in English | EMBASE | ID: covidwho-1885018

ABSTRACT

Background: COVID-19 pandemic presents a consequential threat to individual's mental health in addition to obvious health-related impact. Aim: To focus on prevalence as well as related factors of psychosocial impact of COVID-19 in Lahore, Pakistan. Methods: Our study design was analytical cross-sectional, and study population comprised 382 participants including healthcare workers, teachers, students, and household members. We used non-probability convenience sampling method. We built a structured self-administered questionnaire for collection of data and psychological impact was measured with Impact of Event Scale-Revised (IES-R). Results: Independent factors related to psychological impact were identified using bivariate logistic regression and all significant factors at p-value 0.25 were processed using multivariate model. AORs with 95% CIs were used to assess magnitudes of associations. Prevalence of psychological impact in Pakistan is 53.4%. Being female (β=1.517;AOR=4.561;95%CI: 2.838-7.329)and covering mouth when coughing and sneezing (β=0.486;AOR=1.626;95%CI: 1.012-2.612)are significantly associated with psychosocial impact after logistic regression. Prevalence of psychological impact in Pakistan is very high. Conclusion: Henceforth, policy makers need to consider psychological issues while planning pandemic-related interventions.

13.
American Journal of Respiratory and Critical Care Medicine ; 205:2, 2022.
Article in English | English Web of Science | ID: covidwho-1879944
14.
Antibiotics ; 11(5):547, 2022.
Article in English | ProQuest Central | ID: covidwho-1870879

ABSTRACT

Magnesium, copper, zinc, iron and selenium complexes of ceftriaxone were prepared in a 1:1 ligand to metal ratio to investigate the ligational character of the antibiotic ceftriaxone drug (CFX). The complexes were found to have coordinated and hydrated water molecules, except for the Se (IV) complex, which had only hydrated water molecules. The modes of chelation were explained depending on IR, 1HNMR and UV–Vis spectroscopies. The electronic absorption spectra and the magnetic moment values indicated that Mg (II), Cu (II), Zn (II), Fe (III) and Se (VI) complexes form a six-coordinate shape with a distorted octahedral geometry. Ceftriaxone has four donation sites through nitrogen from NH2 amino, oxygen from triazine, β-lactam carbonyl and carboxylate with the molecular formulas [Mg(CFX)(H2O)2]·4H2O, [Cu(CFX)(H2O)2]·3H2O, [Fe(CFX)(H2O)(Cl)]·5H2O, [Zn(CFX)(H2O)2]·6H2O and [Se(CFX)(Cl)2]·4H2O and acts as a tetradentate ligand towards the five metal ions. The morphological surface and particle size of ceftriaxone metal complexes were determined using SEM, TEM and X-ray diffraction. The thermal behaviors of the complexes were studied by the TGA(DTG) technique. This study investigated the effect of CFX and CFX metal complexes on oxidative stress and severe tissue injury in the hepatic tissues of male rats. Fifty-six male rats were tested: the first group received normal saline (1 mg/kg), the second group received CFX orally at a dose of 180 mg/kg, and the other treated groups received other CFX metal complexes at the same dose as the CFX-treated group. For antibacterial activity, CFX/Zn complex was highly effective against Streptococcus pneumoniae, while CFX/Se was highly effective against Staphylococcus aureus and Escherichia coli. In conclusion, successive exposure to CFX elevated hepatic reactive oxygen species (ROS) levels and lipid peroxidation final marker (MDA) and decreased antioxidant enzyme levels. CFX metal complex administration prevented liver injury, mainly suppressing excessive ROS generation and enhancing antioxidant defense enzymes and in male rats.

15.
Advancements in Life Sciences ; 8(4):333-338, 2021.
Article in English | Scopus | ID: covidwho-1762253

ABSTRACT

T he and spreadoutbreak mortality. of COVIDof Therefore, coronavirus-19−19 which the will researchers (NCoV-19)help in planninghas are developed using to control various a universalthe available diseasecrisis methods andduetotomanage to high study ratethe the ofhealth pattern infectioncare of resources. This study compares Autoregressive Integrated Moving Average (ARIMA) (statistical), Logistic, Gompertz (mathematical) and their hybrid using Wavelet−based Forecast (WBF) models to model and predict the number of confirmed cases of COVID−19. The study area includes the countries: Iran, Italy, Pakistan, Saudi Arabia, USA, UK and Canada. Moreover, root mean squares error (RMSE) is used to compare the performance of studied models. Empirical analysis shows that confirmed cases could be adequately modelled using ARIMA and ARIMA-WBF for all the countries under consideration. However, for future prediction significance of the models varies region to region. © 2021. Advancements in Life Sciences. All rights reserved.

16.
Journal of Population and Social Studies ; 30:408-422, 2022.
Article in English | Scopus | ID: covidwho-1744422

ABSTRACT

The COVID-19 pandemic during initial lockdowns created a problematic situation in which individuals were forced to remain within their homes and were forced to follow social distance restrictions for the well-being of themselves and others. In response, people use social networking sites on mobile phones to gather information about the COVID-19 epidemic. This study aims to investigate the influence of lockdowns on mobile phone usage among university students. Moreover, the harmful effects of COVID-19, such as anxiety, social isolation, and nomophobia among national and international students, are also investigated. The total sample size for this cross-sectional study is 438 individuals. The sample consists of Pakistani students studying at local universities (58.7%) and Pakistani students studying abroad (41.3%). The indigenous data is gathered through convenience sampling. The snowball sampling approach is adopted to acquire data from overseas. The findings show that the excessive use of mobile phones for browsing social networking sites to get information about the pandemic caused COVID-19 anxiety, nomophobia (“no-mobile-phone” phobia), and feelings of social isolation. Our results indicate that the COVID-19 outbreak greatly impacted students' massive mobile phone use and psycho-social well-being, regardless of their geographic location. © 2022. All Rights Reserved.

17.
Proceedings of the Pakistan Academy of Sciences: Part B ; 58(3):65-73, 2021.
Article in English | Scopus | ID: covidwho-1648350

ABSTRACT

The COVID-19 infodemic can be counteracted by clear and consistent communication of scientific evidence and improved health literacy between the public and informants. For complete eradication of COVID-19, several vaccines are approved in various countries for public use by regulatory authorities. Assessing public perception regarding COVID-19 vaccination is an important area of research. In the current study, we aim to evaluate the opinions of individuals from multiple localities about COVID-19 and its vaccination through an online survey. Participants of the study were divided into different groups based on age, profession, demography, and income, and their opinions were calculated in percentage. In age group analysis we reported the highest willingness, 62.8 % (n=22) in age group 30-40, followed by 60 % (n=3) in age group >50, 58.6 % (n=244) in age group 20-30, 57.95 % (n=51) was in age group 15-20 and the least willingness, 33.33 % (n=4) in age group 40-50. The highest disagreement regarding vaccination of 60 % was found in age group >50, followed by 33.3 % in the age group 40-50, 14.7 % in the age group 20-30, 11.4 % in the age group 15-20 and 30-40. Similarly based on profession, maximum acceptability, 59.1 % (n=262) was reported in students, followed by a businessman (68.7 %, n=11), professional workers (3.5 %, n=20). Likewise, in demographic analysis, individuals from Khyber Pakhtunkhwa (KP) (61.3 %, n=200) were found more enthusiastic for vaccination, followed by AJK (58.33 %, n=7) and Islamabad (58.1 %, n=32). In the same way, people with income range $435-$621/month showed the highest willingness (65.7 %, n=69) regarding vaccination, followed by income group ($621 or more $s/month). Surprisingly, individuals from the low-income group were found more interested in vaccination as compared to the higher-income group. Comparatively low interest of high-income group individuals may be due to more exposure to conspiracy theories shared on social media. © Pakistan Academy of Sciences.

18.
Medical Forum Monthly ; 32(9):33-37, 2021.
Article in English | Scopus | ID: covidwho-1548267

ABSTRACT

Objective: To find the students' preference between zoom online and traditional face to face Physiology teaching in undergraduate physical therapy and biotechnology & biological sciences during the COVID-19 pandemic. Study Design: Cross Sectional study Place and Duration of Study: This study was conducted at the Sohail University from April 2021 to June 2021 for a period of 02 months. Materials and Methods: The study participants included 100 Physical therapies and 94 Biotechnology & Biological sciences students. A questionnaire was distributed to each student. The questionnaire included 17 items regarding online and traditional teaching. The students were asked to select a response for each item on the questionnaire including the preferred teaching method from zoom online, traditional, or both. The data were presented in terms of percentage for the individual items, preference in theory, and the overall preferred teaching method. Results: The students gave the opinion that the presence of teacher (82.1%), asking the queries to the teacher (80.2%), giving feedback to the teacher (78.3%), and interest in learning (76.4%) were more important aspects for traditional teaching. Regarding the zoom online lectures, accessibility to the internet hindered online teaching (84%) and online teaching led to more distraction (67.9%). Moreover, a high majority of students (79.2%) preferred the traditional method for theory. The overall preference for the traditional method (83%) was higher as compared to online (2.8%) and both methods (14.2%). Conclusion: The majority of physical therapy and Biotechnology & Biological sciences students had a preference for traditional teaching methods in Physiology. © 2021 Medical Forum Monthly. All rights reserved.

19.
Pakistan Journal of Medical and Health Sciences ; 15(9):2504-2507, 2021.
Article in English | EMBASE | ID: covidwho-1513574

ABSTRACT

Objective: To determine the prevalence of psychological distress among medical doctors during the covid-19 pandemic and identify the coping mechanisms being employed by them. Study Design: Descriptive cross-sectional study. Place and Duration of Study: Department of Community Medicine, HITEC Institute of Medical Sciences, Taxila from 1st February 2020 to 31st July 2020 Methodology: Three hundred and ninety eight doctors (non-specialists, interns, junior consultants and senior consultants) from emergency services, medicine and allied and surgery and allied departments. Results: There were 224 (56.3%) females, 174 (43.7%) were males. Mean age was 35.2±8.6. Majority of participants were from medicine department (n=266,66.8%). Health professionals who worked at frontline during Covid pandemic were 186 (46.7%). One hundred and ninety four (48.7%) participants had no psychological distress, 62 (15.6%) had mild, 30 (7.5%) had moderate and 112 (28.1%) had severe psychological distress. BREIF-COPE questionnaire was found to have high reliability (Cronbach alpha=0.82). High mean scores were observed for Problem focused (4.7±1.4) and Emotional focused coping (4.7±1.1). Relatively low mean score was found for dysfunctional coping (3.3±1.0). A statistically significant low positive correlation ofIES-R scores was observed with Problem focused coping (r=.47, p=.001) and with emotional focused coping (r=.42, p=.001). However, moderately positive correlation was observed between IES-R scores and dysfunctional coping (r=.64, p=.001). Conclusion: Psychological distress was significantly higher among Covid-19 frontline health workers, particularly among postgraduate trainees working in Medicine and Emergency departments.

20.
Research and Practice in Thrombosis and Haemostasis ; 5(SUPPL 2), 2021.
Article in English | EMBASE | ID: covidwho-1509129

ABSTRACT

Background : Covid-19 disease involves respiratory as well as other body systems including cardiovascular, gastrointestinal, neurological, immunological and hematopoietic system. Patient of covid-19 pneumonia presents with wide range of hemostatic abnormalities. These hemostatic abnormalities in COVID-19 are related with disease progression, severity and mortality. Aims : The aim of our study is to evaluate the role of hematological parameters in determination of COVID-19 disease severity. Methods : This was a retrospective study, conducted in Department of Pathology and Department of medicine, FMH college of Medicine and Dentistry from May 2020 to July 2020. Total of 101, confirmed cases of covid-19 disease, both genders between 17 and 75-year age were included. Hematological parameters were compared in mild, moderate, severe and critical disease group. Continuous variables were analyzed by using non parametric, Kruskal Wallis test while categorical variables were analyzed by chi-square test. Results : Out of 101 patients, 20.8%, 51.8%,19.8% and 7.9% were in mild, moderate, severe and critical group respectively. Median (IQR) values of WBCs ( P -value 0.004), ANC ( P -value 0.002), NLR ( P -value 0.001), D-dimer level ( P -value 0.001), ferritin (0.0001), LDH (0.0001) were significantly increased in patients with critical disease. Median (IQR) values of APTT ( P -value 0.003) and CRP ( P -value 0.0001) were suggestively higher in patients with severe disease. Other parameters like Hemoglobin, MCV, HCT, ALC, Platelet count, prothrombin time did not show statistically significant association with severity of disease. Conclusions : The study concluded that Leukocytosis, neutrophilia, elevated Neutrophil to lymphocyte ratio, APTT, D-dimer, LDH, serum ferritin and CRP are associated with severity of covid-19 disease.

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