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J Neonatal Perinatal Med ; 13(3): 307-311, 2020.
Article in English | MEDLINE | ID: covidwho-349047


In the context of SARS-CoV-2 pandemic, the hospital management of mother-infant pairs poses to obstetricians and neonatologists previously unmet challenges. In Lombardy, Northern Italy, 59 maternity wards networked to organise the medical assistance of mothers and neonates with suspected or confirmed SARS-CoV-2 infection. Six "COVID-19 maternity centres" were identified, the architecture and activity of obstetric and neonatal wards of each centre was reorganised, and common assistance protocols for the management of suspected and proven cases were formulated. Here, we present the key features of this reorganization effort, and our current management of the mother-infant dyad before and after birth, including our approach to rooming-in practice, breastfeeding and neonatal follow-up, based on the currently available scientific evidence. Considered the rapid diffusion of COVID-19 all over the world, we believe that preparedness is fundamental to assist mother-infant dyads, minimising the risk of propagation of the infection through maternity and neonatal wards.

Coronavirus Infections , Infection Control , Infectious Disease Transmission, Vertical/prevention & control , Pandemics , Perinatal Care , Pneumonia, Viral , Practice Patterns, Physicians'/trends , Pregnancy Complications, Infectious , Betacoronavirus/isolation & purification , Breast Feeding/methods , COVID-19 , Civil Defense/organization & administration , Coronavirus Infections/epidemiology , Coronavirus Infections/prevention & control , Delivery Rooms/standards , Delivery, Obstetric/methods , Delivery, Obstetric/trends , Female , Humans , Infant, Newborn , Infection Control/methods , Infection Control/organization & administration , Italy/epidemiology , Organizational Innovation , Pandemics/prevention & control , Perinatal Care/methods , Perinatal Care/organization & administration , Perinatal Care/trends , Pneumonia, Viral/epidemiology , Pneumonia, Viral/prevention & control , Pregnancy , Pregnancy Complications, Infectious/epidemiology , Pregnancy Complications, Infectious/prevention & control , SARS-CoV-2
BJOG ; 127(9): 1116-1121, 2020 08.
Article in English | MEDLINE | ID: covidwho-125441


OBJECTIVE: To report mode of delivery and immediate neonatal outcome in women infected with COVID-19. DESIGN: Retrospective study. SETTING: Twelve hospitals in northern Italy. PARTICIPANTS: Pregnant women with COVID-19-confirmed infection who delivered. EXPOSURE: COVID 19 infection in pregnancy. METHODS: SARS-CoV-2-infected women who were admitted and delivered from 1 to 20 March 2020 were eligible. Data were collected from the clinical records using a standardised questionnaire on maternal general characteristics, any medical or obstetric co-morbidity, course of pregnancy, clinical signs and symptoms, treatment of COVID 19 infection, mode of delivery, neonatal data and breastfeeding. MAIN OUTCOME AND MEASURES: Data on mode of delivery and neonatal outcome. RESULTS: In all, 42 women with COVID-19 delivered at the participating centres; 24 (57.1%, 95% CI 41.0-72.3) delivered vaginally. An elective caesarean section was performed in 18/42 (42.9%, 95% CI 27.7-59.0) cases: in eight cases the indication was unrelated to COVID-19 infection. Pneumonia was diagnosed in 19/42 (45.2%, 95% CI 29.8-61.3) cases: of these, 7/19 (36.8%, 95% CI 16.3-61.6) required oxygen support and 4/19 (21.1%, 95% CI 6.1-45.6) were admitted to a critical care unit. Two women with COVID-19 breastfed without a mask because infection was diagnosed in the postpartum period: their newborns tested positive for SARS-Cov-2 infection. In one case, a newborn had a positive test after a vaginal operative delivery. CONCLUSIONS: Although postpartum infection cannot be excluded with 100% certainty, these findings suggest that vaginal delivery is associated with a low risk of intrapartum SARS-Cov-2 transmission to the newborn. TWEETABLE ABSTRACT: This study suggests that vaginal delivery may be associated with a low risk of intrapartum SARS-Cov-2 transmission to the newborn.

Betacoronavirus , Coronavirus Infections/diagnosis , Coronavirus Infections/transmission , Delivery, Obstetric/adverse effects , Infectious Disease Transmission, Vertical , Pneumonia, Viral/diagnosis , Pneumonia, Viral/transmission , Pregnancy Complications, Infectious/diagnosis , Adult , COVID-19 , Female , Humans , Infant, Newborn , Italy , Male , Pandemics , Pregnancy , Pregnancy Complications, Infectious/virology , Retrospective Studies , SARS-CoV-2 , Vagina/virology