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Cities and Health ; 2022.
Article in English | Scopus | ID: covidwho-2187935


The COVID-19 pandemic has exacerbated health and socioeconomic disparities and limited access to both social services and health care. According to national public vaccination strategies, the Ministry of Health of the city of Buenos Aires has led the Butterfly Effect Project. The main objective was to implement a population-specific strategy aimed to surmount these challenges by promoting vaccination to unhoused and at-risk people in the city of Buenos Aires (Argentina). This case study presents the main findings of a survey within the Butterfly Effect Project that explored the obstacles and opportunities faced by unhoused and at-risk people in the city of Buenos Aires in terms of access to the health care system during the pandemic. The study also analyzed perceptions of both COVID-19 and the vaccination campaign. This qualitative exploratory study was conducted through semi-structured interviews carried out with unhoused and at-risk people between June and July 2021. Through this project, the city of Buenos Aires vaccinated more than 10,000 people in vulnerable social and housing situations, including unhoused people and people at risk of becoming unhoused. Peer companions, Paradores (public shelters), and homes for unhoused people were considered ‘essential' during the pandemic. © 2022 Informa UK Limited, trading as Taylor & Francis Group.

Medicina ; 81(3):408-414, 2021.
Article in English | GIM | ID: covidwho-1619327


This study describes the incidence of early events supposedly attributable to vaccination or immunization (ESAVI) that occurred in healthcare workers who had been inoculated with the first component of the Sputnik V vaccine. Safety at 72 h post-immunization was analyzed based on a self-reported form. Between January 5 and January 20, 2021, in Buenos Aires, Argentina, a total of 707 healthcare workers (median age 35 yrs, female 67%) were vaccinated. The response rate was 96.6% (n: 683) and 487 (71.3%) participants reported at least one ESAVI. The incidence rate was 6.3 per 1000 person/hours. The total number of ESAVIs was 1434. A total of 469 local reactions were reported, 57% of the participants reported pain at the injection site, and 11% had redness and swelling. A total of 968 systemic reactions were informed, including new or worsened muscle pain, referred by 58% of the participants, fever referred by 40%, and diarrhea referred by 5%. Five percent (n: 34) had serious adverse events and one participant had to be hospitalized. The ESAVI rate was higher in females than males (66.4% versus 51.4%;HR 1.38;95% CI 1.13-5.38) and in workers younger than 55 yrs old (63.0% versus 28.0%;HR 2.66;95% CI 1.32-5.38). This study demonstrates high rates of early local and systemic reactions. However, serious events were rare. Studies on long-term safety, stratified by sex and age, are needed.

Medicina ; 81(2):135-142, 2021.
Article in English | GIM | ID: covidwho-1472861


Most countries in Latin America have already reported thousands of confirmed cases and vulnerable populations are the most affected by the coronavirus disease 2019 (COVID-19) pandemic. Preventive measures such as hygiene, social distancing, and isolation, essential to stop the spread of coronavirus, are difficult to accomplish for vulnerable populations due to their living conditions. Seroepidemiological surveys are assets to measure the transmission for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Until July 1st, the incidence rate of SARS-CoV-2 infection in Barrio Padre Mugica, one of the largest slums in Buenos Aires City, was 5.9%. This study aimed to establish the prevalence of SARS-CoV-2 antibodies immunoglobulin G (IgG) immediately after the outbreak, and to identify neighbourhood, household and individual factors associated with seroconversion. The prevalence based on IgG was 53.4% (95% CI 52.8% to 54.1%). For each polymerase chain reaction (RT-qPCR) confirmed case, nine people tested IgG positive, indicating a high rate of undetected (probably asymptomatic) infections. Hence, the high rate of undiagnosed people suggests that clinical criteria and epidemiological nexus should be considered. The high seroprevalence observed in the context of an intense epidemic in a vulnerable area might serve as a reference to other countries. This study contributes to future decision making by understanding population immunity against SARS-CoV2 and its relation to living conditions and foccus that comprehensive biosocial, household-level interventions are needed.