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1.
Revista De Comunicacion-Peru ; 21(1):49-65, 2022.
Article in Spanish | Web of Science | ID: covidwho-1780419

ABSTRACT

The migration of creators from other platforms and the emergence of new lines of content are contributing to the thematic diversification of Twitch.tv beyond its leadership in gaming. This article explores the potential for collaboration, education, and creation of live-streaming platforms by analyzing the online coworking experience of the JaimeAltozano 'working room' on Twitch, launched after the outbreak of the Covid-19 pandemic. An initiative that gathered 222,172 hours worked by the community in three months. Using a mixed methods research design, the experience was studied on the basis of quantitative data, 67 in-depth interviews with users and ethnographic techniques for content analysis. The results obtained in the three phases of the research process show that experiences like the JaimeAltozano 'working room' are useful virtual spaces for productivity. Based on these results, a map of the phenomenon was drawn using six key concepts: gamification, synchronicity, community, participation, free operability, and common atmosphere. In the face of the growing platformization of cultural goods, our research delves into the media reality of Twitch beyond videogaming to explore the possibilities of live-streaming for the digital community's media empowerment.

2.
Portuguese Journal of Pediatrics ; 53(1):435-439, 2022.
Article in English | Scopus | ID: covidwho-1716408

ABSTRACT

Acute chest syndrome is a life-threatening complication in sickle cell disease. Infections are frequently implied, and like other viruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be a trigger. In addition, due to their inflammatory status, they may present a higher risk for severe coronavirus disease 2019 (COVID-19). Pneumonia and acute chest syndrome share clinical, laboratory, and radiological features and may overlap, which makes their differential diagnosis especially challenging. We describe a case of an adolescent with homozygous sickle cell disease that developed acute chest syndrome in the context of COVID-19. With it, we intend to bring awareness to the potential role of imaging in the differential diagnosis and in establishing the best approach for the patient. Chest computed tomography findings were suggestive of an alternative diagnosis to COVID-19 pneumonia and red cell transfusion, fluid management, analgesics, and antibiotics were administered with favorable outcome. © Author(s) (or their employer(s)) and Portuguese Journal of Pediatrics 2022.

3.
Revista Espanola De Salud Publica ; 95:15, 2021.
Article in English | Web of Science | ID: covidwho-1609973

ABSTRACT

The COVID-19 pandemic is clearly showing the importance for the surveillance and protection of human health of acting in all settings of life: family, community, education, leisure or work, among others, as well as addressing the multiple determinants that influence the health and well-being of the population: demographic, healthcare, environmental, social, economic, cultural or occupational, among others. With respect to occupational health and the work-related determinants of health, the potential of occupational health services acting at the company level is clear, and could be generalized to almost any public health action setting. This article reflects on the opportunities for coordination between the occupational health system in Spain (including resources from mutual insurance companies, companies themselves and administrations) and the public health system, including both health care (primary care, hospital) and public health services. We examine this in the context of health crises, like the present one, but also with a broader vision, commensurate with the necessary comprehensive care for human health, guaranteeing health as a fundamental and universal right in all life circumstances. To advance along these lines, we propose the incorporation of the "occupational health perspective" in all actions and services of the public healthcare system, especially with respect to public health services under the purview of the health administration.

4.
Pediatric Diabetes ; 22(SUPPL 30):86-87, 2021.
Article in English | EMBASE | ID: covidwho-1570994

ABSTRACT

Introduction: The rate of diabetic ketoacidosis (DKA) in new-onset type 1 diabetes mellitus (T1D) is multifactorial. There seems to be an inverse relationship between T1D's incidence and DKA's frequency. DKA has been reported to be more common among young children. Recently, the COVID-19 pandemic has posed additional challenges as to diagnosing T1D. Objectives: We aimed to assess the rate of DKA and associated risk factors in pediatric new-onset T1D in a large pediatric diabetes center in Portugal. Methods: Retrospective analysis of data of patients referred to a level III pediatric hospital between January 1st, 2013 and December 31th, 2020 (8 years). Results: We included 276 children and adolescents with a median age of 9,6 years, 20,1% under 5 years old. A mean incidence of 35 new cases/year was observed, with an upward trend. Newonset T1D cases under 5 years old raised progressively, having more than tripled throughout the study period (n=3 in 2013 vs. n=10 in 2020). In total, 38% children and adolescents presented with DKA, ranging from 23,3% in 2013 to 43,2% in 2020, while remaining stable (37,2%-40,9%) in the period in-between. Overall, DKA was considered severe in 24,8% of cases, ranging from 6% in 2017 to 47% in 2020. 20 (7,2%) patients were admitted to the intensive care unit. DKA at presentation was more frequent in the age group under 2 years old (p=0,016), in which 80% of patients presented with DKA. Non-DKA presentation was associated with family history of T1D (p=0,005). Conclusions: Our study shows an upward trend in T1D's incidence in children under 5 years old and a high DKA rate at disease onset, which was more frequent in patients under 2 years of age. In the first year of COVID-19 pandemic, 43% of DKA was considered severe. It is urgent to implement educational programs to promote earlier diagnosis. Broader studies are required to provide a representative national landscape of the epidemiology of T1D in pediatric population in Portugal.

5.
Pediatric Diabetes ; 22(SUPPL 30):49, 2021.
Article in English | EMBASE | ID: covidwho-1570993

ABSTRACT

Introduction: On 12th March 2020, a national lockdown was imposed in Portugal, as a response to rising COVID-19 cases. Since then healthcare access patterns were deeply modified. Objectives: In this study, we tried to understand what shifted from prior years in new-onset type 1 diabetes mellitus (T1D). Methods: It was performed a retrospective analysis of patients referred to a level III pediatric hospital from March 2020 until March 2021. Patients admitted during the same period in the 3 previous years were set as control group. Results: Since lockdown imposition, 44 children and adolescents were diagnosed T1D, contrasting with prior mean incidence of 32 cases/ year. Median age was 9,9 years (min. 0,5 - max. 15,8). Children under 2 years-old represented 4,9% of cases, contrasting with only 2,1% in previous years. All subjects were tested for SARS CoV-2 but only 2 were positive. When comparing to prior years, subjects presenting with less than one week of symptoms almost doubled in 2020, (19,5% vs. 10,4%), and a higher rate of diabetic ketoacidosis (DKA) was also observed (53,7%, vs. 38,5%). DKA severity was also higher (40,9% vs. 21,6%;p=0,02 and 14,6% subjects required admission to intensive care unit. Conclusions: Similarly to other reports, a higher number of new-onset T1D was observed, with a comparable increase in severity. In contrast to what might have been expected, DKA prevalence and severity was not necessarily linked to delayed diagnosis. We estimate that such severity may be related to a higher proportion of younger patients. While the role of SARS CoV-2 exposure in pancreatic islet cells destruction is still under investigation, antibody assessment and detailed contact history could help to explain the increased prevalence and severity of new-onset T1D during the pandemic period.

6.
Revista Espanola de Salud Publica ; 95:17, 2021.
Article in Spanish | MEDLINE | ID: covidwho-1519194

ABSTRACT

The COVID-19 pandemic is clearly showing the importance for the surveillance and protection of human health of acting in all settings of life: family, community, education, leisure or work, among others, as well as addressing the multiple determinants that influence the health and well-being of the population: demographic, healthcare, environmental, social, eco-nomic, cultural or occupational, among others. With respect to occupational health and the work-related determinants of health, the potential of occupational health services acting at the company level is clear, and could be generalized to almost any public health action setting. This article reflects on the opportunities for coordination between the occupational health system in Spain (including resources from mutual insurance companies, companies themselves and administrations) and the public health system, including both health care (primary care, hospital) and public health services. We examine this in the context of health crises, like the present one, but also with a broader vision, commensurate with the necessary comprehensive care for human health, guaranteeing health as a fundamental and universal right in all life circumstances. To advance along these lines, we propose the incorporation of the "occupational health perspective" in all actions and services of the public healthcare system, especially with respect to public health services under the purview of the health administration.

7.
Studies in Systems, Decision and Control ; 358:501-519, 2021.
Article in English | Scopus | ID: covidwho-1340319

ABSTRACT

Based on a combination of cognitively inspired methods in artificial intelligence such as artificial mathematical intelligence and data mining, we study the correlation between the COVID-19 pandemic and the sentiment analysis (qualitative ontological nature) of tweets and their linguistic patterns from the presidents and the populations of five countries from Europe (Spain and the United Kingdom), North America (The United States of America), and South America (Chile and Colombia). The results show that tweets classified as negative are the most common in all presidential tweeter accounts, except in one country, Colombia. However, tweets classified as neutral are dominant in the population tweets in each country examined. Based on the results obtained and on some of the foundational cognitive techniques of artificial mathematical intelligence, we conclude by providing COVID-19 prevention guidelines at the linguistic and cognitive levels. © 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.

8.
Bone Marrow Transplantation ; 56:37-39, 2021.
Article in English | EMBASE | ID: covidwho-1333909

ABSTRACT

Background: Axicabtagen Ciloleucel (axi-cel) is approved in Europe for the treatment of adults with R/R large B-cell lymphoma (LBCL), primary mediastinal B-cell lymphoma (PMBCL) and transformed follicular lymphoma (tFL). In Spain, nationwide CAR-T administration requests are reviewed centrally within the Ministry of Health. We analyzed the real-world outcomes of patients treated with axicel under the commercial label in Spanish centers. Methods: Six designated centers for commercial CAR-T administration collected data on behalf of GETH-GELTAMO. Data were collected retrospectively from consecutive patients in whom apheresis was performed for axi-cel treatment from Febrruary-2019 to November-2020. CRS and ICANS were graded with the ASTCT consensus criteria. Response was assessed according to the Lugano criteria. Results: 106 patients with R/R lymphoma underwent apheresis for axi-cel. At data cutoff, 92 (87%) received infusion. The reasons for not undergoing infusion were progression-related death in 12 (86%), tumor lysis syndrome in 1 (7%) and complete response after bridging therapy in 1 (7%). Of note, 14 patients were conditioned and infused during the peak of COVID-19 epidemic in Spain (March-April 2020). Median time from Ministry approval to infusion was 54 days. Histology consisted of 74% DLBCL with 11% tFL, and 15% PMBCL. Disease status at lymphodepletion was PD in 69%, SD in 22% and PR in 9%. All patients received lymphodepletion. Median time from leukapheresis to start of lymphodepletion was 34 days. Median time from leukapheresis to infusion was 39 days. Median hospitalization period was 21 days. Any grade of CRS occurred in 86% of pts (18% grade 2, 6.5% grades 3-4). Tocilizumab was used in 58% of patients who developed CRS, corticosteroids in 19%. ICANS was diagnosed in 42.5% of pts (10% grade 2, 15% grade 3-4). Treatment for ICANS included corticosteroids in 78%, tocilizumab in 31%, siltuximab in 15%, and anakinra in 21%. ICU admission was needed in 20 patients (22%). 4 patients died in the context of ICANS, 1 due to CRS, and 1 due to infection. Of 80 patients evaluable and restaged at day 30, ORR was 78% with 40% CR, 38% PR, 11% PD and 11% SD or indeterminate. Of 58 patients evaluable at day 100, 66% had ongoing response (CR 48%, PR 18%). Of 23 patients evaluable at day 180, 65% presented CR. Of 39 patients who showed PR/SD at day 30, 9 (23%) converted to CR. After a median follow-up of 6.3 months, EFS and OS were 55.5% and 78%, respectively in the infused population, with an estimated median EFS and OS of 13.1 and 7.3 months. In the intention-to-treat analysis for all patients who underwent apheresis, median estimated OS and EFS were 12.3 (95%CI 8.9-15.7) and 6.6 months (95%CI 4.6-8.5), respectively (Figure 1). Conclusions: This Spanish multicenter retrospective analysis shows encouraging results of axi-cell treatment in patients with R/R aggressive B-cell lymphoma in the real-world setting. Significant toxicity events were less frequent than those reported in the pivotal trial, however events of mortality associated to toxicity occurred. With a limited follow-up time, response outcomes are favorable.

9.
Journal of Sensor and Actuator Networks ; 10(2):12, 2021.
Article in English | Web of Science | ID: covidwho-1298175

ABSTRACT

At present, capacity control in indoor spaces is critical in the current situation in which we are living in, due to the pandemic. In this work, we propose a new solution using machine learning techniques with BLE technology. This study presents a real experiment in a university environment and we study three different prediction models using machine learning techniques-specifically, logistic regression, decision trees and artificial neural networks. As a conclusion, the study shows that machine learning techniques, in particular decision trees, together with BLE technology, provide a solution to the problem. The contribution of this research work shows that the prediction model obtained is capable of detecting when the COVID capacity of an enclosed space is exceeded. In addition, it ensures that no false negatives are produced, i.e., all the people inside the laboratory will be correctly counted.

10.
Sci Total Environ ; 791: 148252, 2021 Oct 15.
Article in English | MEDLINE | ID: covidwho-1253612

ABSTRACT

In the current pandemic context, it is necessary to remember the lessons learned from previous outbreaks in Africa, where the incidence of other diseases could rise if most resources are directed to tackle the emergency. Improving the access to water, sanitation and hygiene (WASH) could be a win-win strategy, because the lack of these services not only hampers the implementation of preventive measures against SARS-CoV-2 (e.g. proper handwashing), but it is also connected to high mortality diseases (for example, diarrhoea and lower respiratory infections (LRI)). This study aims to build on the evidence-based link between other LRI and WASH as a proxy for exploring the potential vulnerability of African countries to COVID-19, as well as the role of other socioeconomic variables such as financial sources or demographic factors. The selected methodology combines several machine learning techniques to single out the most representative variables for the analysis, classify the countries according to their capacity to tackle public health emergencies and identify behavioural patterns for each group. Besides, conditional dependences between variables are inferred through a Bayesian network. Results show a strong relationship between low access to WASH services and high LRI mortality rates, and that migrant remittances could significantly improve the access to healthcare and WASH services. However, the role of Official Development Assistance (ODA) in enhancing WASH facilities in the most vulnerable countries cannot be disregarded, but it is unevenly distributed: for each 50-100 US$ of ODA per capita, the probability of directing more than 3 US$ to WASH ranges between 48% (Western Africa) and 8% (Central Africa).


Subject(s)
COVID-19 , Sanitation , Africa/epidemiology , Bayes Theorem , Humans , Hygiene , Pandemics , SARS-CoV-2 , Water , Water Supply
11.
ESMO Open ; 6(2): 100104, 2021 04.
Article in English | MEDLINE | ID: covidwho-1174237

ABSTRACT

BACKGROUND: The COVID-19 pandemic has impacted all aspects of modern-day oncology, including how stakeholders communicate through social media. We surveyed oncology stakeholders in order to assess their attitudes pertaining to social media and how it has been affected during the pandemic. MATERIALS AND METHODS: A 40-item survey was distributed to stakeholders from 8 July to 22 July 2020 and was promoted through the European Society for Medical Oncology (ESMO) and the OncoAlert Network. RESULTS: One thousand and seventy-six physicians and stakeholders took part in the survey. In total, 57.3% of respondents were medical oncologists, 50.6% aged <40 years, 50.8% of female gender and mostly practicing in Europe (51.5%). More than 90% of respondents considered social media a useful tool for distributing scientific information and for education. Most used social media to stay up to date on cancer care in general (62.5%) and cancer care during COVID-19 (61%) given the constant flow of information. Respondents also used social media to interact with other oncologists (78.8%) and with patients (34.4%). Overall, 61.1% of respondents were satisfied with the role that social media was playing during the COVID-19 pandemic. On the other hand, 41.1% of respondents reported trouble in discriminating between credible and less credible information and 30% stated social networks were a source of stress. For this reason, one-third of respondents reduced its use during the COVID-19 pandemic. Regarding meeting attendance, a total of 59.1% of responding physicians preferred in-person meetings to virtual ones, and 51.8% agreed that virtual meetings and social distancing could hamper effective collaboration. CONCLUSION: Social media has a useful role in supporting cancer care and professional engagement in oncology. Although one-third of respondents reported reduced use of social media due to stress during the COVID-19 pandemic, the majority found social media useful to keep up to date and were satisfied with the role social media was playing during the pandemic.


Subject(s)
COVID-19 , Oncologists , Social Media , Adult , Aged , Attitude of Health Personnel , Attitude to Computers , Female , Humans , Information Dissemination , Male , Medical Oncology/education , Middle Aged , Oncologists/psychology , Social Networking , Stress, Psychological , Surveys and Questionnaires , Telemedicine
12.
Revista Cubana de Pediatria ; 92:1-11, 2020.
Article in Spanish | Scopus | ID: covidwho-825571

ABSTRACT

Epilepsy is the most frequent neurologic treatable disease in Pediatrics. The current COVID19 epidemic has limited the attention to patients with epilepsy. Telemedicine is one of the technological resources that allow using remote medicine for diagnosis as well as for treatments and distance learning. The objective of this review is to show the potentials of telemedicine as an alternative to conventional consultations. Telemedicine services used in other countries have proved to be very useful in keep giving remote health services to people with epilepsy. Telemedicine includes mobile and landline telephony, text messaging, e-mails and video calls using different digital tools. Through telemedicine it can be specified the degree of crisis control, to adjust or change medications, to advise on the lifestyle in this times of isolation, to insist in the importance of a good hygiene of the sleep, and to give psychological support to the child and the family. It has been demonstrated that telemedicine is not inferior than in situ consultations regarding crisis control, hospitalization, visits to emergency services or adherence to medication;and it is more economic because it drops expenses, and the time used in transportation to the hospital. It is recommended the promotion and institutional provision of telemedicine to provide remote medical care in cases of pediatric epilepsy as a great alternative in the era of COVID-19. © 2020, Editorial Ciencias Medicas. All rights reserved.

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