The importance of indoor air quality (IAQ) to reduce infectious disease transmission has become clear during the COVID-19 pandemic. In addition to SARS-CoV-2, other diseases, including RSV and influenza, are spread by airborne transmission, and often indoors-where most people spend over 90% of their lives. Given the importance of indoor environments in the spread of infectious disease, ventilation and filtration to improve IAQ should play a major role in preparing for a global catastrophic biological risk event (GCBR). This study involves performing a review of peer-reviewed literature and reports about improving indoor air quality in public spaces and interviewing technical experts in the fields of indoor air, building ownership, IAQ policy, and disease transmission control. The goal of the study is to identify and develop near and long-term policy actions for improving IAQ aimed to reduce GCBRs and other infectious diseases at various levels, including local and national. © 2022 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022. All rights reserved.