Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 19 de 19
Filter
1.
Journal of Hepatology ; 77:S14, 2022.
Article in English | EMBASE | ID: covidwho-1967492

ABSTRACT

Background and aims: Approval of a drug therapy for NASH requires a very good safety/tolerability profile and acceptable therapeutic index. MAESTRO-NAFLD-1 (NCT04197479) is a randomized doubleblind (DB) Phase 3 clinical trial of placebo (PBO) versus resmetirom (RES), a once-a-day oral selective thyroid hormone receptor β agonist, in >1100 patients with NAFLD with safety as the primary end point. Method: Enrollment was Dec 2019 to Oct 2020 at 79 US sites. Requirements included 3 metabolic risk factors, fibroscan (FS) ≥5.5 kPa/CAP≥280 dBm, MRI-PDFF≥8%. Randomization was 1:1:1:1 to 3 DB arms, PBO, 80 or 100 mg RES (n = 972) or an 100 mg open label (OL) arm (n = 171). The primary objective was to evaluate the safety and tolerability of 80 or 100 mg RES versus PBO measured by the incidence of adverse events (AEs). Results: At baseline the DB safety population (n = 969) was age 55.9 (11.8);female, 54.4%, white 88.6%;hispanic 34.7%;BMI 35.3 (6.0) type 2 diabetes 49%, hypertension 76.1%, dyslipidemia 87.9%;FS 7.4 (4.7) kPa. Discontinuations (22.5%) did not differ by treatment, most patient decision (pandemic related). DB compliancewas impacted by COVID drug kit delays. AE withdrawals were 80 mg, 2.4%;100 mg, 2.8%;PBO, 1.3%. The primary objective was met. TEAEs were 80 mg, 88.4%;100 mg, 86.1%;PBO, 81.8%. TEAEs ≥grade 3 severity were 80 mg, 7.6%;100 mg, 9.0%;PBO, 9.1%. AEs in excess of PBOwere grade 1–2 AEs of diarrhea (80 mg, 23.5%;100 mg, 31.2%;PBO, 13.8%) and nausea (80 mg, 11.9%;100 mg, 18.2%;PBO, 7.9%), in the first few weeks. ALT increases ≥3XULN were 80 mg, 0.61%;100 mg, 0.31%;PBO,1.6%. Therewere no changes in bodyweight or HR. BP decreased by 2–3 mmHg in the RES arms. Key 2o end points were met (Table). Comparative mean reduction in FS VCTE was not significant;a responder analysis of FS and MRE showed significant reductions with RES treatment. Conclusion: RES achieved the primary safety end point in this 52- week Phase 3 NAFLD clinical trial that identified patients by metabolic risk and non-invasive imaging. Key 2o end points were met including LDL-C, ApoB, triglycerides, MRI-PDFF, FS (CAP).(Table Presented) 1MRE combined RES groups.

2.
Journal of Clinical Urology ; 15(1):50-51, 2022.
Article in English | EMBASE | ID: covidwho-1957028

ABSTRACT

Introduction: The COVID-19 pandemic placed a strained NHS under further pressure, resulting in a significant backlog of work. Fundamental change is needed to improve efficiency and allow service re-establishment with a capability to deal with this backlog. Outpatient service structure will be pivotal to the recovery. Within this, intelligent triage plays a key role. Our department has 5 triaging consultants for benign disease GP referrals, interdepartmental referrals, and electronic consultations with 4 departmental Programmed Activities weekly. Patients and Methods: Data from the NHS e-referral system (e-RS) for the 12 months commencing December 2020 was accessed. Data from our E-consultation services was obtained for the same period. Data comprised total referrals, referrals accepted, and referrals managed with advice and guidance without consultation (AAG). E-consultation services were analysed for total volume, and the resulting outpatient consultations. AAG was streamlined using a library of standard guidance for common conditions. Results: From 3380 e-RS referrals, 23.7% were managed with AAG. Some inter-consultant triage variability was observed but appeared unrelated to individual consultant years of experience. Similarly, with E-consultation there was some variability between clinicians in conversion rates to outpatient consultations. Conclusions: Using senior clinicians in intelligent triage ensures appropriate use of outpatient consultations, with 23.7% of e-RS referrals managed with AAG. Whilst argument may be made for administrative staff fulfilling the triage role, we feel algorithmic triaging is suboptimal for patient safety. Appropriate AAG, red flag identification, appropriate timescales for outpatient review, and accurate direction to subspecialty clinics are all enhanced by consultant involvement.

3.
Journal of Clinical Urology ; 15(1):81-82, 2022.
Article in English | EMBASE | ID: covidwho-1957017

ABSTRACT

Introduction: There is growing recognition that bladder outlet obstruction (BOO) surgery can often be safely performed as a day case procedure. The BOO surgery day case rate (DCR) is a Getting It Right First Time (GIRFT) quality metric. Patients awaiting BOO surgery represent the largest group awaiting elective surgical treatment in urology. This unmet need has expanded considerably due to the Covid-19 pandemic. Patients and Methods: Model Hospital (MH) is a datadriven improvement tool for English NHS trusts, which utilises routinely collected national level data. MH describes performance metrics for transurethral resection of prostate, laser prostatectomy, prostatic urethral lift, and bladder neck incision. MH data were analysed for all 115 trusts performing BOO surgery over 12 months to October 2021. Associations between service delivery and outcome metrics were tested. Results: Table 1 shows national Trust-level metrics for DCR, length of stay (LOS), 30-day readmission rate (30D), annual centre volume (ACV), and waiting list time (WLT). Analysis indicated no significant association between any of the following;DCR and 30D (Spearman rank correlation coefficient (rs)=-0.085, p=0.37), ACV and 30D (rs=- 0.019, p=0.84), DCR and WLT (rs=0.16, p=0.096). Conclusion: There is wide variation in DCR and WLT nationally. The absence of association between DCR and 30D suggests that many trusts can safely increase DCR for BOO surgery. Optimising DCR could help to facilitate the post-Covid Elective Recovery for surgery. The lack of association between DCR and WLT, however, suggests that further resource constraints beyond elective inpatient bed availability influence the provision of BOO surgery.

4.
J Thromb Haemost ; 2022 Jul 16.
Article in English | MEDLINE | ID: covidwho-1949716

ABSTRACT

BACKGROUND: Erythrocyte aggregation is a phenomenon that is commonly found in several pathological disease states: stroke, myocardial infarction, thermal burn injury, and COVID-19. Erythrocyte aggregation is characterized by rouleaux, closely packed stacks of cells, forming three-dimensional structures. Healthy blood flow monodisperses the red blood cells (RBCs) throughout the vasculature; however, in select pathological conditions, involving hyperthermia and hypoxemia, rouleaux formation remains and results in occlusion of microvessels with decreased perfusion. OBJECTIVES: Our objective is to address the kinetics of rouleaux formation with sudden cessation of flow in variable temperature and oxygen conditions. METHODS: RBCs used in this in vitro system were obtained from healthy human donors. Using a vertical stop-flow system aligned with a microscope, images were acquired and analyzed for increased variation in grayscale to indicate increased aggregation. The onset of aggregation after sudden cessation of flow was determined at proscribed temperatures (37-49°C) and oxygen (0%, 10%), and in the presence and absence of 4, 4'-Diisothiocyano-2,2'-stilbenedisulfonic acid (DIDS). Both autologous and homologous plasma were tested. RESULTS: RBCs in autologous plasma aggregate faster and with a higher magnitude with both hyperthermia and hypoxemia. Preventing deoxyhemoglobin from binding to band 3 with DIDS (dissociates the cytoskeleton from the membrane) fully blocks aggregation. Further, RBC aggregation magnitude is greater in autologous plasma. CONCLUSIONS: We show that the C-terminal domain of band 3 plays a pivotal role in RBC aggregation. Further, aggregation is enhanced by hyperthermia and hypoxemia.

5.
Diabetic Medicine ; 39(SUPPL 1):99-100, 2022.
Article in English | EMBASE | ID: covidwho-1868609

ABSTRACT

Objective: To adapt Diabetes Education and Self-Management for Ongoing and Newly Diagnosed (DESMOND) structured education programmes for virtual delivery during covid-19. Methods: Face-to- face structured education programmes stopped in March 2020 due to covid-19. A multi-disciplinary stakeholder group adapted the existing evidence-based DESMOND curriculums and resources to support a new model of virtual delivery, while remaining congruent to the theoretical and philosophical underpinnings. Version 1 was released in May 2020. Educator training was provided to increase confidence in delivering virtually. An iterative process of stakeholder feedback, and review of resources led to two updated versions of the adapted programmes being released;version 3 was made available in October 2021. New Educators are now trained virtually. In August 2021 the first Educator completed their pathway of training, mentorship and quality assessment virtually. Results: Between May 2020 and August 2021, 529 attendees rated their DESMOND programme 8.8/10 for how much they felt part of the group and able to engage with others and 94% set a goal during their programme. 95% of attendees rated their overall experience as 4 or 5 stars with 97% recommending the programme to friends and family. Feedback from Educators indicated low drop out rates between sessions and virtual delivery had increased the opportunity for evening and weekend sessions enabling more people to attend. Educators found the virtual resources easy to use. Conclusions: The adaptation of face-to- face to virtual delivery is acceptable to participants and Educators. Virtual delivery should continue to be included as an option in the future.

6.
International Journal of Obstetric Anesthesia ; 50:46, 2022.
Article in English | ScienceDirect | ID: covidwho-1814537
10.
IISE Annual Conference and Expo 2021 ; : 698-703, 2021.
Article in English | Scopus | ID: covidwho-1589498

ABSTRACT

Election infrastructure includes socio-technical systems that are designated as United States critical infrastructure within the Government Facilities sector. Following the 2016 United States' General Election and during the 2020 Presidential Election cycle, election security and the integrity of election processes became a prevalent, national conversation. From the 2019 U.S. Senate Intelligence Committee report indicating that election systems in all 50 states had been targeted by foreign adversaries to the more recent broadened use of, and concern about, mail-based voting during the COVID-19 pandemic, election integrity is increasingly important. Furthermore, poll workers play a crucial role in elections and election equipment, as they are one of the first lines of defense in systems security. This paper contributes to improving the security of election infrastructure through intentional, targeted, cyber, physical, and insider threat training for poll workers. Specifically, this paper details the engineering design, including pedagogical approach, and deployment of online, election-specific, threat training modules. Results of a System Usability Scale assessment from 44 poll workers indicate the content and online platform are easy to interact with and use. Further, the developed modules were piloted and then deployed in a mid-Atlantic state;participating counties include over 1,900 poll workers who serve nearly 750,000 voters. © 2021 IISE Annual Conference and Expo 2021. All rights reserved.

11.
Blood ; 138:1834, 2021.
Article in English | EMBASE | ID: covidwho-1582149

ABSTRACT

Introduction: High dose therapy with Autologous Stem Cell Transplantation (ASCT) has traditionally been performed as an inpatient procedure. However, with improvements in care and patient selection it is possible to safely deliver conditioning chemotherapy and supportive care in an Daytherapy setting (Kodad SG et al., 2019). While deemed an “outpatient procedure” this method is often delivered on large day units which requires the patient to attend daily, often only spending overnight at home. To reduce these daily visits the Clinical Haematology Department of Peter MacCallum and Royal Melbourne Hospital (CHD) in collaboration with the Hospital in the Home department (HIHD) at Royal Melbourne Hospital developed an innovative program to safely deliver supportive care for Myeloma Patients undergoing ASCT at home (HIH-ASCT). The HIHD is an acute inpatient unit that exists as a “virtual” inpatient ward. Patients are reviewed daily by a HIHD Doctor with twice daily visits by a HIHD Nurse for administration of supportive care measures (e.g. intravenous electrolyte and fluid replacement) in the comfort of their home. Here we report on the safety outcomes of our HIH-ASCT program, specifically patient complications and outcomes. Methods: A retrospective case note audit identified 54 consecutive HIH-ASCT patients who received HIH-ASCT for Myeloma between 2018 and 2021 under HIHD. Patients were eligible for our HIH-ASCT program if they had Myeloma requiring ASCT;an ECOG ≤1;had not been admitted to ICU previously;lived within 30 minutes drive of the hospital;had a safe home environment (for both the patient and visiting staff) and a carer who could stay with them throughout their HIH-ASCT. While undertaking HIH-ASCT patients did not receive prophylactic antibiotics and they were not routinely given GCSF to minimise the risk of engraftment fevers. Results: Of those treated as HIH-ASCT patients the median age was 60 years (range 33-72). 39% patients were female (n=21) and 61% male (n=33). Underlying disease groups included IgA (n=8;15%), IgG (n=35;64%), IgM (n=1;2%), Light Chain (n=9;17%) and Oligosecretory (n=1;2%). 43% had High-risk Cytogenetics. ASCT-1 (n=48;88%), ASCT-2 (n=5;9%) and one patient underwent a ASCT-Tandem (both under HIHD). Conditioning regimes included Melphalan200 (n=37;68%), Velcade-Melphan200 (n=13;23%) and Carfilzomib-Melphalan200 (n=5;9%). The average stem dose was 3.80 x10 6/kg (range 2.14-8.4). Median time to Neutrophil engraftment was 12 days (range = 10-21) and Platelet engraftment 12 days (range = 8-18). The total number of bed days saved through the HIH-ASCT program was 466, with a median length of stay (LOS) under the HIHD team of 9 days (Range = 3-14). In addition, 3 patients were not readmitted to the hospital (6%) and were discharged directly from the HIHD team. The most common reason for readmission was fever (n=43;80%), of which only 11 were culture positive, and diarrhoea (n=44;81%). Only 1 patient required intensive care support. There were no deaths. The median LOS as an inpatient once readmitted was 6 days (range = 2-27). In regards to cost savings, an acute inpatient bed under the CHD is approximately $1300 USD versus $900 USD per day for a HIHD bed. This equated to a potential cost saving for the CHD of approximately $186000 USD. Conclusion: The delivery of supportive care for patients undergoing HIH-ASCT in is both safe and effective with comparable outcomes for what would be expected for an inpatient cohort. It resulted in a median of 9 bed days saved per patient (total number of bed days saved = 466). This is important as it allowed our department to increase bed capacity across the unit without the associated costs of building a new ward. In addition, during our COVID-19 outbreaks the HIH-ASCT program has allowed us to continue to deliver optimal patient care, while minimising the infection risk for our patients. More recently we have introduced remote monitoring (e.g. temperature, heart rate, blood pressure and oxygen saturations) with video reviews with the aim of increasing the capacity of our HIHD and further improving the HIH-ASCT experience for our patients. Disclosures: Routledge: Amgen: Honoraria, Speakers Bureau;Sandoz: Consultancy, Honoraria, Speakers Bureau;BMS: Honoraria. Harrison: Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau;Abbvie: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau;GSK: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau;Eusa: Consultancy, Honoraria, Speakers Bureau;Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees;Celgene/ Juno/ BMS: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau;Terumo BCT: Consultancy, Honoraria;Janssen Cilag: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau;Novartis: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau;Sanofi: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau;Roche/Genentech: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau;Haemalogix: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau. Ritchie: CRISPR Therapeutics: Research Funding;Amgen Inc: Honoraria, Research Funding;Novartis: Honoraria;CSL: Honoraria;BMS: Research Funding;Takeda: Research Funding.

12.
PUBMED; 2021.
Preprint in English | PUBMED | ID: ppcovidwho-293140

ABSTRACT

Memory B cell reserves can generate protective antibodies against repeated SARS-CoV-2 infections, but with an unknown reach from original infection to antigenically drifted variants. We charted memory B cell receptor-encoded monoclonal antibodies (mAbs) from 19 COVID-19 convalescent subjects against SARS-CoV-2 spike (S) and found 7 major mAb competition groups against epitopes recurrently targeted across individuals. Inclusion of published and newly determined structures of mAb-S complexes identified corresponding epitopic regions. Group assignment correlated with cross-CoV-reactivity breadth, neutralization potency, and convergent antibody signatures. mAbs that competed for binding the original S isolate bound differentially to S variants, suggesting the protective importance of otherwise-redundant recognition. The results furnish a global atlas of the S-specific memory B cell repertoire and illustrate properties conferring robustness against emerging SARS-CoV-2 variants.

15.
Diabetic Medicine ; 38(SUPPL 1):67, 2021.
Article in English | EMBASE | ID: covidwho-1238415

ABSTRACT

Aim: To understand how patients find the experience of attending virtual group education during the covid-19 pandemic. Method: Diabetes Education and Self-Management for Ongoing and Newly Diagnosed (DESMOND) programmes for people with or at risk of type 2 diabetes were adapted for virtual delivery in late May 2020, so UK and Ireland DESMOND providers could implement virtual groups during covid-19. 14 DESMOND providers distributed online surveys at the end of each group;either via chat functions or follow-up emails. A range of questions were included rating how participants had found the experience before and during attendance. The responses were all entered anonymously and automatically analysed by the online survey software. Results: To date 147 responses have been received with an average overall experience rating of 4.7 out of five was given. 97% reported finding it easy to log into their virtual group. 92% were happy to attend virtually rather than waiting to attend in-person. 93% felt able to express how they were feeling about their type 2 diabetes. 93% were able to keep up with the information provided. 90% reported feeling part of a group. 94% reported making a plan to make a lifestyle change with 68% focusing on weight loss/maintenance and 19% on HbA1c. 97% would recommend attending. Conclusion: Although implementation is in early stages these initial findings suggest those who attend a virtual DESMOND group find the overall experience positive. It is envisaged that virtual means of group delivery will now become part of diabetes education provision permanently.

16.
Diabetic Medicine ; 38(SUPPL 1):65-66, 2021.
Article in English | EMBASE | ID: covidwho-1238406

ABSTRACT

Aim: Healthier You (HY) is an NHS England commissioned diabetes prevention programme meeting criteria for structured education programmes (SEPs). It is evidence-based, informed by theory, underpinned with a philosophy and usually delivered as sixteen 90 minute face-to- face group sessions for participants at risk of type 2 diabetes. We decided to adapt HY for virtual delivery to enable this SEP to continue during covid-19. We aimed to examine the uptake and impact of this new delivery mode. Method: A multidisciplinary group of stakeholders reviewed and modified the programme to support virtual delivery, while retaining credibility as SEP. HY facilitators were trained in the new mode of delivery. Delivery of virtual HY began April 2020. Data was collated over 2 time periods;face-to- face delivery (2019) and virtual delivery (1/4/2020-1/ 12/2020) and compared for acceptability and accessibility. Results: Uptake to face-to- face HY was 66%, increasing to 69.5% for virtual delivery during covid-19. An increase in attendance of people <35 years of age (12% vs. 5%), from non-White groups (30% vs. 23%) and from the most deprived quintile of deprivation (28% vs. 17%) was seen for virtual HY compared to face-to- face. Average weight loss improved with virtual delivery compared to face-to- face (3.6 kg vs. 2.4 kg). Conclusions: Since covid-19, there has been increased uptake to virtual HY by those who are younger, employed, from BAME background and/or socially deprived areas. Fewer older, retired people attended. Post-covid- 19, a hybrid approach to HY delivery may support accessibility and equity while improving weight loss.

17.
Diabetic Medicine ; 38(SUPPL 1):66, 2021.
Article in English | EMBASE | ID: covidwho-1238397

ABSTRACT

Objective: To provide training and support to build confidence of educators delivering an adapted portfolio of diabetes education and self-management for ongoing and newly diagnosed (DESMOND) structured education programmes (i.e. newly diagnosed and foundation programme, let's prevent diabetes, and walking away from diabetes) during the covid-19 pandemic. Methods: The DESMOND curriculums and resources were adapted from face to face delivery to support virtual delivery, but remain congruent to the theoretical and philosophical underpinning of the interventions and content. A virtual DESMOND academy was established offering a portfolio of 2 hour workshops (delivered through MS TEAMS) to support existing DESMOND educators with confidence to set up and deliver bespoke DESMOND programmes. Workshops included a demonstration of visual resources available to support virtual delivery and discussions about how to use behaviour change techniques based on the DESMOND philosophy and learning theories virtually. Attendees provided feedback via an online survey. Results: To date (18.01.2021) 47 workshops have been delivered to 329 attendees. Post-training surveys show: 95% of attendees rated the workshop as useful/very useful and 84% felt more confident to deliver virtually afterwards. Aspects of training reported as most useful were;an overview of the visual aids, facilitation skills for virtual delivery and sharing good practice. The main concern was the use of, and access to, reliable technology by educators and participants. Conclusions: Workshops designed to build confidence of educators to deliver self-management education virtually are effective in increasing educator confidence. Technology skills and access are concerns that need to be further addressed.

18.
Intervention ; 19(1):37-47, 2021.
Article in English | Scopus | ID: covidwho-1183962

ABSTRACT

On March 11, 2020, COVID-19 was declared a pandemic by the World Health Organization. In response to the sudden rise in COVID-19-related mental health and psychosocial impacts, we embarked on a digital training (e-learning) and remote delivery adaptation for Problem Management Plus Training for Helpers (Remote PM+ Training) based in New York City, four European countries and six African countries. This paper provides an overview of the two Remote PM+ Trainings, including key adaptations and lessons learned across the contexts. Trainings were approximately 75 hours in duration, with a mix of group and individual work, in diverse contexts. Overall, remotely delivered PM+ training and intervention appear appropriate. There were a number of critical lessons learned that contributed to the efficacy of the trainings, such as technological support, digital literacy, preparation and flexibility among the trainers and the trainees. There is also a need for cultural and contextual adaptation towards the delivery of remote training and implementation of PM+. However, the outcomes from these two trainings indicate that PM+ may be adapted for remote (online) training and, if supported with additional studies, could build workforce capacity in contexts in which there is limited in-person access to mental health and psychosocial support services and staff. © 2021 Lippincott Williams and Wilkins. All rights reserved.

19.
J Intern Med ; 290(2): 349-358, 2021 08.
Article in English | MEDLINE | ID: covidwho-1072638

ABSTRACT

BACKGROUND: Radiological and pathological studies in severe COVID-19 pneumonia (SARS-CoV-2) have demonstrated extensive pulmonary immunovascular thrombosis and infarction. This study investigated whether these focal changes may present with chest pain mimicking pulmonary emoblism (PE) in ambulant patients. METHODS: CTPAs from outpatients presenting with chest pain to Leeds Teaching Hospital NHS Trust 1st March to 31 May 2020 (n = 146) and 2019 (n = 85) were compared. Regions of focal ground glass opacity (GGO), consolidation and/or atelectasis (parenchymal changes) were determined, and all scans were scored using British Society for Thoracic Imaging (BSTI) criteria for COVID-19, and the 2020 cohort was offered SARS-CoV-2 antibody testing. RESULTS: Baseline demographic and clinical data were similar between groups with absence of fever, normal lymphocytes and marginally elevated CRP and D-Dimer values. Evidence of COVID-19 or parenchymal changes was observed in 32.9% (48/146) of cases in 2020 compared to 16.5% (14/85) in 2019 (P = 0.007). 11/146 (7.5%) patients met BSTI criteria for COVID-19 in 2020 compared with 0/14 in 2019 (P = 0.008). 3/39 patients tested had detectable COVID-19 antibodies (2 with parenchymal changes and 1 with normal parenchyma) however 0/6 patients whose CTPA met BSTI criteria "likely/suspicious for COVID-19" and attended antibody testing were SARS-CoV-2 antibody positive. CONCLUSIONS: 32.8% ambulatory patients with suspected PE in 2020 had parenchymal changes with 7.5% diagnosed as COVID-19 infection by imaging criteria, despite the absence of other COVID-19 symptoms. These findings suggest that localized COVID-19 pneumonitis with immunothrombosis occurs distal to the bronchiolar arteriolar circulation, causing pleural irritation and chest pain without viraemia, accounting for the lack of fever and systemic symptoms.


Subject(s)
COVID-19/diagnosis , Chest Pain/etiology , Clinical Audit , Computed Tomography Angiography , Diagnosis, Differential , Female , Humans , Lung/diagnostic imaging , Male , Middle Aged , Pulmonary Embolism/diagnosis , Retrospective Studies
SELECTION OF CITATIONS
SEARCH DETAIL