Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 153
Filter
1.
2nd Workshop Reducing Online Misinformation through Credible Information Retrieval, ROMCIR 2022 ; 3138:11-26, 2022.
Article in English | Scopus | ID: covidwho-1871081

ABSTRACT

The worldwide COVID-19 pandemic has brought about a lot of changes in people's life. It also emerges as a new challenge to information search services. This is because up to now our understanding about the virus is still limited, and there is a lot of misinformation online. In such a situation, how to provide useful and correct information to the public is not straightforward. Responsibility of search engines is crucial because many people make decisions based on the information available to them. In this piece of work, we try to improve retrieval quality via the data fusion technique. Especially, a clustering-based approach is proposed for selecting a subset of systems from all available ones for finding relevant, credible, and correct documents. Experimented with a group of runs submitted to the 2020 TREC Health Misinformation Track, we demonstrate that data fusion is a very beneficial approach for this task, whether measured by some traditional metrics such as MAP or some task specific metrics such as CAM. When choosing 17 runs, which is one third of all component retrieval systems available, the linear combination method is better than the best component retrieval system by 31.42% in MAP and 21.72% in CAM. The proposed methods are also better than the state-of-the-art subset selection method by a clear margin. © 2022 Copyright @Anonymous for this paper by its authors.

2.
Chinese Journal of Biologicals ; 34(5):560-565, 2021.
Article in Chinese | EMBASE | ID: covidwho-1857139

ABSTRACT

Objective To evaluate the specificity of three consecutive batches of 2019-nCoV nucleic acid detection kit (fluorescence PCR) manufactured by Shanghai GeneoDx Biotech Co., LTD. Methods A total of 55 common respiratory pathogens, including endemic human coronaviruses (HKU1, OC43, NL63 and 229E), severe acute respiratory syndrome conronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS), seasonal influenza virus, rhinovirus, adenovirus, Klebsiella pneumonia and Mycobacterium tuberculosis, were grouped and used for verification of cross reactivity of the detection kit. According to the requirements in the Key Points of Technical Review for Registration of 2019 New Coronavirus Nucleic Acid Detection Reagents issued by Center for Medical Device Evaluation, National Medical Products Administration (NMPA), human mucoprotein, human blood, phenylephrine, oxymetazoline, sodium chloride (including those as preservatives) and other 29 interfering substances were selected to verify the anti-interference substances of this kit. Results In the verification for cross reactivity, the test results of mixed positive samples by the three consecutive batches of kit were positive, while those of negative samples were negative, indicating a coincidence rate of accuracy of 100%. The cross-reactive substances showed no effect on the test result by the kit. All the test results of positive and borderline positive samples were positive, while those of negative samples were negative, indicating a coincidence rate of accuracy of 100%. All the 29 kinds of endogenous / exogenous interfering substances showed no influence on the test results by this kit. Conclusion Hie new coronavirus 2019-nCoV nucleic acid detection kit (fluo¬rescence PCR method) manufactured by Shanghai GeneoDx Biotech Co., LTD. showed no cross-reactivity with 55 common respiratory pathogens, while showed anti-interference properties against endogenous and exogenous interfering substances such as host tissue, common respiratory pathogen and common drugs for respiratory diseases in clinic. The specificity test result of the kit met the requirements for registration of 2019 new coronavirus nucleic acid detection reagents. The test results of three consecutive batches of kits were highly stable.

3.
Zhonghua Liu Xing Bing Xue Za Zhi ; 43(5):655-662, 2022.
Article in Chinese | PubMed | ID: covidwho-1848753

ABSTRACT

2019-nCoV Omicron (B.1.1.529) variant, which has brought new challenges to the prevention and control of COVID-19 pandemic, has the characteristics of stronger transmissibility and more rapid transmission and more significant immune evasion. It took only two months to become a predominant strain worldwide after its identification in South Africa in November 2021. Local epidemics caused by Omicron variant have been reported in several provinces in China. However, the epidemiological characteristics of highly mutated Omicron variant remain unclear. This article summarizes the progress in the research of functional mutations, transmissibility, virulence, immune evasion and cross-reactive immune responses of Omicron variant, to provide references for the effective prevention and control of COVID-19 pandemic caused by Omicron variant.

4.
Environmental Chemistry ; 40(7):1945-1957, 2021.
Article in Chinese | Scopus | ID: covidwho-1847652

ABSTRACT

Since the outbreak of the new coronavirus pneumonia (COVID-19) in December 2019, it has caused millions of deaths in more than 200 countries all over the world, and the global economic development has been severely impacted. Concerning the new type of coronavirus (SARS-CoV-2) that caused the epidemic, scientific research has been actively carried out around the world as well as various prevention and control measures, which made important contribution to protect human health. However, as one of the countries that made outstanding achievements in the prevention and control of the epidemic, there were some regional epidemics of “object-to-human transmission” and then “human-to-human transmission ” occurred after June 2020, indicating the complexity of the spread of SARS-CoV-2. In addition, the development of COVID-19 in some contraries is going uncontrollable recently, and infection cases of the SARS-CoV-2 variant strain have appeared in many countries, which made the prevention and control of the epidemic more difficult. This article briefly reviewed the updated research works on SARS-CoV-2, including possible sources of virus and infection mechanisms, diagnosis and treatment approaches, transmission characteristics and environmental impact, etc. In particular, the environmental factors affecting the transmission of SARS-CoV-2 are summarized in order to enhance the understanding of environmental transmission of SARS-CoV-2. © 2021, Science Press. All rights reserved.

5.
13th International Conference on E-Education, E-Business, E-Management, and E-Learning, IC4E 2022 ; : 605-610, 2022.
Article in English | Scopus | ID: covidwho-1840637

ABSTRACT

Supply management plays an important role in the business. In our research, we make the introduction with research background in COVID-19, in the APPLE Inc. and large amount of data is constructed. Several methods are used during the task, for example, literature review, data analysis, quantitative analysis and comparative analysis. The research shows the current problems faced by electronic technology companies, which are instability of the supply chains, material shortage and regional policies, after which the research reasons for deep causes and provides feasible improvements of the company, which are production concentration, purchase limit strategy, online commodity physical models, price reduction, and comprehensive capital. © 2022 ACM.

6.
Recent Advances in Ophthalmology ; 41(10):996-1000, 2021.
Article in Chinese | Scopus | ID: covidwho-1835960

ABSTRACT

The corona virus disease 2019(COVID-19)pandemic induced by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a major global public health threat. Both the SARS-CoV-2 and SARS-CoV etiologic agents belong to the subfamily of beta human coronavirus, and their genomic similarity is up to 79.6%. Both SARS-CoV and SARS-CoV-2 infect the host cell through angiotensin converting enzyme-2. At present, it has been shown that SARS-CoV-2 infection is associated with conjunctivitis. Therefore, that whether the SARS-COV-2 can be infected or transmitted through the eye is also of great concern, but it still a lack of clinically confirmed cases and laboratory evidence of its ocular transmission. This review focuses on the etiological characteristics, epidemiologic features, ocular presentation of SARS-CoV-2 and the conjunctival sac infection rate, and the possibility of SARS-CoV-2 transmission through the ocular tissue will be discussed. © 2021, Xinxiang Medical University. All rights reserved.

7.
Annals of Translational Medicine ; : 12, 2022.
Article in English | Web of Science | ID: covidwho-1822668

ABSTRACT

Background: New England Journal of Medicine (NEJM), Lancet, Journal of the American Medical Association (JAMA), and British Medical Journal (BMJ) are collectively known as "the Top Four Medical Journals (TFMJ)" in China. Through the analysis of Chinese scholars' publications in the TFMJ in the recent 10 years, this study aimed to clarify the current situation of high-quality medical research conducted by Chinese scholars and institutions. Methods: Data were retrieved and downloaded manually from PubMed (2011-2020). Information on the publication year, journal, author, affiliation, and citation, etc. were extracted and analyzed using R software. Results: A total of 761 articles were involved in the final analysis. The number of articles published by Chinese scholars in the TFMJ was 135/29,942 (0.45%) in BMJ, 124/14,033 (0.88%) in JAMA, 314/16,117 (1.94%) in Lancet, and 188/15,242 (1.23%) in NEJM (P<0.001). Besides, the letter was the main research type, which was up to 44.54%, and the original research only accounted for 17.47%. The most popular subspecialty and subject were infectious diseases and COVID-19, respectively. The most productive researcher was Chen Wang, and Bin Cao was the most cited Chinese scholar. The most productive institute was Chinese Academy of Medical Sciences and Peking Union Medical College. The most cited study was "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China". Conclusions: The presence of Chinese scholars in the TFMJ has grown, but there is still much room to improve. A Matthew effect in China's high-level scientific research was demonstrated.

8.
PubMed; 2021.
Preprint in English | PubMed | ID: ppcovidwho-333823

ABSTRACT

Antibodies that potently neutralize SARS-CoV-2 target mainly the receptor-binding domain or the N-terminal domain (NTD). Over a dozen potently neutralizing NTD-directed antibodies have been studied structurally, and all target a single antigenic supersite in NTD (site 1). Here we report the 3.7 A resolution cryo-EM structure of a potent NTD-directed neutralizing antibody 5-7, which recognizes a site distinct from other potently neutralizing antibodies, inserting a binding loop into an exposed hydrophobic pocket between the two sheets of the NTD beta-sandwich. Interestingly, this pocket has been previously identified as the binding site for hydrophobic molecules including heme metabolites, but we observe their presence to not substantially impede 5-7 recognition. Mirroring its distinctive binding, antibody 5-7 retains a distinctive neutralization potency with variants of concern (VOC). Overall, we reveal a hydrophobic pocket in NTD proposed for immune evasion can actually be used by the immune system for recognition. HIGHLIGHTS: Cryo-EM structure of neutralizing antibody 5-7 in complex with SARS CoV-2 spike5-7 recognizes NTD outside of the previously identified antigenic supersite5-7 binds to a site known to accommodate numerous hydrophobic ligandsStructural basis of 5-7 neutralization tolerance to some variants of concern.

9.
PubMed; 2021.
Preprint in English | PubMed | ID: ppcovidwho-333792

ABSTRACT

Patients with COVID-19 present with a wide variety of clinical manifestations. Thromboembolic events constitute a significant cause of morbidity and mortality in patients infected with SARS-CoV-2. Severe COVID-19 has been associated with hyperinflammation and pre-existing cardiovascular disease. Platelets are important mediators and sensors of inflammation and are directly affected by cardiovascular stressors. In this report, we found that platelets from severely ill, hospitalized COVID-19 patients exhibit higher basal levels of activation measured by P-selectin surface expression, and have a poor functional reserve upon in vitro stimulation. Correlating clinical features to the ability of plasma from COVID-19 patients to stimulate control platelets identified ferritin as a pivotal clinical marker associated with platelet hyperactivation. The COVID-19 plasma-mediated effect on control platelets was highest for patients that subsequently developed inpatient thrombotic events. Proteomic analysis of plasma from COVID-19 patients identified key mediators of inflammation and cardiovascular disease that positively correlated with in vitro platelet activation. Mechanistically, blocking the signaling of the FcgammaRIIa-Syk and C5a-C5aR pathways on platelets, using antibody-mediated neutralization, IgG depletion or the Syk inhibitor fostamatinib, reversed this hyperactivity driven by COVID-19 plasma and prevented platelet aggregation in endothelial microfluidic chamber conditions, thus identifying these potentially actionable pathways as central for platelet activation and/or vascular complications in COVID-19 patients. In conclusion, we reveal a key role of platelet-mediated immunothrombosis in COVID-19 and identify distinct, clinically relevant, targetable signaling pathways that mediate this effect. These studies have implications for the role of platelet hyperactivation in complications associated with SARS-CoV-2 infection. Cover illustration: ONE-SENTENCE SUMMARY: The FcgammaRIIA and C5a-C5aR pathways mediate platelet hyperactivation in COVID-19.

10.
PubMed; 2021.
Preprint in English | PubMed | ID: ppcovidwho-333778

ABSTRACT

Emergence of novel variants of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) underscores the need for next-generation vaccines able to elicit broad and durable immunity. Here we report the evaluation of a ferritin nanoparticle vaccine displaying the receptor-binding domain of the SARS-CoV-2 spike protein (RFN) adjuvanted with Army Liposomal Formulation QS-21 (ALFQ). RFN vaccination of macaques using a two-dose regimen resulted in robust, predominantly Th1 CD4+ T cell responses and reciprocal peak mean neutralizing antibody titers of 14,000-21,000. Rapid control of viral replication was achieved in the upper and lower airways of animals after high-dose SARS-CoV-2 respiratory challenge, with undetectable replication within four days in 7 of 8 animals receiving 50 microg RFN. Cross-neutralization activity against SARS-CoV-2 variant B.1.351 decreased only ~2-fold relative to USA-WA1. In addition, neutralizing, effector antibody and cellular responses targeted the heterotypic SARS-CoV-1, highlighting the broad immunogenicity of RFN-ALFQ for SARS-like betacoronavirus vaccine development. SIGNIFICANCE STATEMENT: The emergence of SARS-CoV-2 variants of concern (VOC) that reduce the efficacy of current COVID-19 vaccines is a major threat to pandemic control. We evaluate a SARS-CoV-2 Spike receptor-binding domain ferritin nanoparticle protein vaccine (RFN) in a nonhuman primate challenge model that addresses the need for a next-generation, efficacious vaccine with increased pan-SARS breadth of coverage. RFN, adjuvanted with a liposomal-QS21 formulation (ALFQ), elicits humoral and cellular immune responses exceeding those of current vaccines in terms of breadth and potency and protects against high-dose respiratory tract challenge. Neutralization activity against the B.1.351 VOC within two-fold of wild-type virus and against SARS-CoV-1 indicate exceptional breadth. Our results support consideration of RFN for SARS-like betacoronavirus vaccine development.

11.
PubMed; 2021.
Preprint in English | PubMed | ID: ppcovidwho-333760

ABSTRACT

The emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants stresses the continued need for next-generation vaccines that confer broad protection against coronavirus disease 2019 (COVID-19). We developed and evaluated an adjuvanted SARS-CoV-2 Spike Ferritin Nanoparticle (SpFN) vaccine in nonhuman primates (NHPs). High-dose (50 micro g) SpFN vaccine, given twice within a 28 day interval, induced a Th1-biased CD4 T cell helper response and a peak neutralizing antibody geometric mean titer of 52,773 against wild-type virus, with activity against SARS-CoV-1 and minimal decrement against variants of concern. Vaccinated animals mounted an anamnestic response upon high-dose SARS-CoV-2 respiratory challenge that translated into rapid elimination of replicating virus in their upper and lower airways and lung parenchyma. SpFN's potent and broad immunogenicity profile and resulting efficacy in NHPs supports its utility as a candidate platform for SARS-like betacoronaviruses. ONE-SENTENCE SUMMARY: A SARS-CoV-2 Spike protein ferritin nanoparticle vaccine, co-formulated with a liposomal adjuvant, elicits broad neutralizing antibody responses that exceed those observed for other major vaccines and rapidly protects against respiratory infection and disease in the upper and lower airways and lung tissue of nonhuman primates.

12.
PubMed; 2021.
Preprint in English | PubMed | ID: ppcovidwho-333657

ABSTRACT

Understanding protective mechanisms of antibody recognition can inform vaccine and therapeutic strategies against SARS-CoV-2. We discovered a new antibody, 910-30, that targets the SARS-CoV-2 ACE2 receptor binding site as a member of a public antibody response encoded by IGHV3-53/IGHV3-66 genes. We performed sequence and structural analyses to explore how antibody features correlate with SARS-CoV-2 neutralization. Cryo-EM structures of 910-30 bound to the SARS-CoV-2 spike trimer revealed its binding interactions and ability to disassemble spike. Despite heavy chain sequence similarity, biophysical analyses of IGHV3-53/3-66 antibodies highlighted the importance of native heavy:light pairings for ACE2 binding competition and for SARS-CoV-2 neutralization. We defined paired heavy:light sequence signatures and determined antibody precursor prevalence to be ~1 in 44,000 human B cells, consistent with public antibody identification in several convalescent COVID-19 patients. These data reveal key structural and functional neutralization features in the IGHV3-53/3-66 public antibody class to accelerate antibody-based medical interventions against SARS-CoV-2. HIGHLIGHTS: A molecular study of IGHV3-53/3-66 public antibody responses reveals critical heavy and light chain features for potent neutralizationCryo-EM analyses detail the structure of a novel public antibody class member, antibody 910-30, in complex with SARS-CoV-2 spike trimerCryo-EM data reveal that 910-30 can both bind assembled trimer and can disassemble the SARS-CoV-2 spikeSequence-structure-function signatures defined for IGHV3-53/3-66 class antibodies including both heavy and light chainsIGHV3-53/3-66 class precursors have a prevalence of 1:44,000 B cells in healthy human antibody repertoires.

13.
PubMed; 2020.
Preprint in English | PubMed | ID: ppcovidwho-333640

ABSTRACT

BACKGROUND: Several candidate vaccines to prevent COVID-19 disease have entered large-scale phase 3 placebo-controlled randomized clinical trials and some have demonstrated substantial short-term efficacy. Efficacious vaccines should, at some point, be offered to placebo participants, which will occur before long-term efficacy and safety are known. METHODS: Following vaccination of the placebo group, we show that placebo-controlled vaccine efficacy can be derived by assuming the benefit of vaccination over time has the same profile for the original vaccine recipients and the placebo crossovers. This reconstruction allows estimation of both vaccine durability and potential vaccine-associated enhanced disease. RESULTS: Post-crossover estimates of vaccine efficacy can provide insights about durability, identify waning efficacy, and identify late enhancement of disease, but are less reliable estimates than those obtained by a standard trial where the placebo cohort is maintained. As vaccine efficacy estimates for post-crossover periods depend on prior vaccine efficacy estimates, longer pre-crossover periods with higher case counts provide better estimates of late vaccine efficacy. Further, open-label crossover may lead to riskier behavior in the immediate crossover period for the unblinded vaccine arm, confounding vaccine efficacy estimates for all post-crossover periods. CONCLUSIONS: We advocate blinded crossover and continued follow-up of trial participants to best assess vaccine durability and potential delayed enhancement of disease. This approach allows placebo recipients timely access to the vaccine when it would no longer be proper to maintain participants on placebo, yet still allows important insights about immunological and clinical effectiveness over time.

14.
Acta Medica Mediterranea ; 38(2):1099-1102, 2022.
Article in English | EMBASE | ID: covidwho-1798617

ABSTRACT

Objective: In this example, the patient accidentally fell from 8 meters high, causing trauma to the patient’s chest with tracheal laceration and ‘white lung’ in both lungs. The patient lost respiratory function and was using a breathing machine with 100% pure oxygen while still maintaining 80% oxygen saturation. Routine tracheal intubation under general anaesthesia could potentially cause patient death during the operation. The objective was to assess the use of extracorporeal membrane oxygenation (ECMO) in surgery to repair the patient’s tracheal laceration. Methods: The thoracic surgery department applied hybrid surgery combined with ECMO to rescue the patient. With the support of ECMO, the patient’s intraoperative vital signs were stable, blood oxygen saturation was 100% and the surgery for repairing the laceration with fibreoptic bronchoscopy was successfully completed. Results: The patient recovered and was discharged from hospital. Conclusion: ECMO has successfully treated many critically ill COVID-19 patients during the pandemic, but this is the first time in China that ECMO has been applied to patients suffering from multiple critical injuries such as chest trauma and tracheal laceration.

15.
2nd International Congress on Optics, Electronics and Optoelectronics, ICOEO 2021 ; 2226, 2022.
Article in English | Scopus | ID: covidwho-1795407

ABSTRACT

Coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, is a potentially fatal disease of global public health concern. Fever has been reported to be a common clinical symptom in COVID-19 and current CDC recommendations for mitigation of community COVID-19 transmission include temperature screening, so prompting widespread temperature screening across multiple sectors, including hospitals, office buildings and airports. The need for no-contact and rapid measurement of body temperature during the COVID-19 pandemic emergency has led to the widespread use of thermal imaging cameras. However, the body temperature measurement is also disturbed by the environment factors, including ambient temperature, background light etc. When the ambient temperature is low, the temperature of the patient will also be low. It was difficult to screen the fever patients by using the absolute temperature criteria, and it often result in missing detection. In order to solve this problem, this paper proposed a method of screening COVID-19 symptom fever patients by the body temperature difference detection. The temperature difference detection method combined the temperature measurement of the infrared imaging camera and the visible camera face recognition. This method will eliminate environmental interference and equipment errors, to reduce the probability of the fever missed detection. © Published under licence by IOP Publishing Ltd.

16.
7th ACM SIGIR Conference on Human Information Interaction and Retrieval, CHIIR 2022 ; : 12-24, 2022.
Article in English | Scopus | ID: covidwho-1789003

ABSTRACT

Numerous information-Tracking solutions have been implemented worldwide to fight the COVID-19 pandemic. While prior work has heavily explored the factors affecting people's willingness to adopt contact-Tracing solutions, which inform people when they have been exposed to someone positive for COVID-19, numerous countries have implemented other information-Tracking solutions that use more data and more sensitive data than these commonly studied contact-Tracing apps. In this work, we build on existing work focused on contact-Tracing apps to explore adoption and design considerations for six representative information-Tracking solutions for COVID-19, which differ in their goals and in the types of information they collect. To do so, we conducted semi-structured interviews with 44 participants to investigate the factors that influence their willingness to adopt these solutions. We find four main categories of influences on participants' willingness to adopt such solutions: individual benefits of the solution, societal benefits of the solution, functionality concern, and digital safety (e.g., security and privacy) concerns. Further, we enumerate the factors that inform participants' evaluations of these categories. Based on our findings, we make recommendations for the future design of information-Tracking solutions and discuss how different factors may balance against benefits in future crisis situations. © 2022 ACM.

17.
2022 IEEE International Conference on Consumer Electronics, ICCE 2022 ; 2022-January, 2022.
Article in English | Scopus | ID: covidwho-1779086

ABSTRACT

Wearing a facial mask has become a must in our daily life due to the global COVID-19 pandemic. However, the performance of conventional face recognition systems severely degrades for faces occluded by masks. How to combat the effect of occlusion on face recognition is an important issue. However, the performance of existing methods developed for masked face recognition unpleasantly degrades when dealing with unmasked faces. To address this issue for real-world applications, where the gallery image or the probe image may be a masked or unmasked face, we propose the concept of balanced facial feature matching and, based on it, design a robust masked face recognition system. The matching is balanced because it is performed on features extracted from corresponding facial regions. The system consists of a classification network and two feature extractors. The classification network classifies an input face image into a masked face or an unmasked face. One feature extractor extracts the feature of a full face, and the other uses a guided perceptual loss to focus the feature extraction on the non-occluded part of the face. The system is tested on both synthetic and real data. The face verification accuracy is improved by 2.4% for the synthetically masked LFW dataset, 1.9% for the MFR2 dataset, and 5.4% for the RMFD dataset. The results further show that the system improves masked face recognition while preserving the performance of unmasked face recognition. © 2022 IEEE.

18.
Journal of Services Marketing ; : 15, 2022.
Article in English | Web of Science | ID: covidwho-1779050

ABSTRACT

Purpose The pandemic has accelerated the use of virtual learning spaces and led to rethinking post-pandemic course delivery. However, it remains unclear whether students' online engagement in e-servicescapes can influence attachment to a place, i.e. a physical servicescape. This study conducted an exploratory study to inform place attachment and actor engagement literature in an online service context. Design/methodology/approach Quantitative survey design was used and 98 usable responses were collected from undergraduate and postgraduate students at a major New Zealand university during the COVID-19 pandemic in 2020. The questionnaire consisted of 23 items relating to three dimensions of online student engagement and 19 items referring to six dimensions of campus attachment. Findings Results of the exploratory study indicate that classmate community in online lectures, referring to student-student interactions, can positively influence five of the dimensions of campus attachment, including place identity, place dependence, affective attachment, social bonding and place memory, even though students are physically not on campus. However, it cannot influence place expectation. Moreover, instructor community (student-instructor interaction) and learning engagement (student-content interaction) in online lectures have insignificant impact on campus attachment. Research limitations/implications This study emphasises the social dimension when interacting in e-servicescapes. Person-based interactions are more influential than content-based interactions for student engagement. Educational service providers should integrate the e-servicescape and the physical servicescape by encouraging more student-student interactions to contribute to service ecosystem well-being at the micro, meso and macro levels. Originality/value This study indicates that customer-to-customer interaction serves to integrate customer engagement across the digital and physical realms for process-based services like education.

19.
5th International Conference on Crowd Science and Engineering, ICCSE 2021 ; : 61-67, 2021.
Article in English | Scopus | ID: covidwho-1774997

ABSTRACT

The distributed accounting method of blockchain, together with its decentralized and tamper proof characteristics, can solve the problem of lack of food safety traceability data and low credibility, which enable the traceability requirements of food chain traceability, problem food recall, food circulation information query. It also improves the food flow mode, and establishes a new food safety ecosystem. This paper innovatively integrates the principle of blockchain into the traceability and circulation process of Hebei cold chain food. In order to find the proportion and distribution of various types of commodities in the circulation of imported and domestic cold chain food in Hebei Province, the combination of qualitative and quantitative analysis methods, chi square test, association rules and other analysis methods are used. The results show that the demand for cold chain food in Hebei Province is mainly domestic food and supplemented by imported food. Cold chain poultry is the main need and other cold chain food is supplement. The flow of imported cold chain food is mainly from the surrounding provinces and cities. Furthermore, in the process of tracing the positive commodities, it is found that there are four main modes of commodity circulation in Hebei Province, namely, family model from farmer, wholesale market, new retail and multi-level sales model. The new retail and multi-level sales model fill the gap in the distribution and circulation of cold chain goods in Hebei Province. © 2021 ACM.

SELECTION OF CITATIONS
SEARCH DETAIL