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1.
Global Spine Journal ; 12(3):169S, 2022.
Article in English | EMBASE | ID: covidwho-1938246

ABSTRACT

Introduction: Blended learning, which combines in-person learning and e-learning, has grown rapidly in education. Advantages of this modality include control over content, learning sequence, and pace of learning, allowing participants to tailor their experiences to meet their personal learning objectives. Blended learning enables adaptive and collaborative learning and transforms the teacher's role from transmitting knowledge (instructing) to facilitating learning. Objectives: Our study aimed to assess the efficacy of blended learning in a pediatric scoliosis training program through the largest Surgical Training Institution in Sub-Saharan Africa, The College of Surgeons of East, Central and Southern Africa (COSECSA). Material and Methods: The course comprised of three parts;1-the online portion, which allowed participants to review lectures, papers, and audiovisual materials over a 3-week period;2-the in-person session, where participants spent a full day with an international expert, reviewing cases in a team-based approach and coming to a consensus on treatment strategy;and 3-a one week, in-person experience where participants were exposed to pre-surgical planning conferences, clinic, casting, and scrubbing into surgeries with international experts. All participants completed a Needs Assessment (NA) and quiz prior to the course. The NA contained 6 various topics, with 3 questions for each topic scored by a 10-point scale in pediatric spine deformity. The quiz included 15 surgical and clinical questions related to the pediatric spine deformity topics. The NA and quiz were taken before the course, after the online session, and after the in-person session. A final survey was conducted at the end of the in-person surgical week. Results: Thirty-six orthopedic surgeons and neurosurgeons enrolled in the course primarily from Tanzania, Kenya, and Malawi. The NA assessment scores improved significantly over the course of the three surveys from 67.3 prior to the course, to 90.9 mid-course, and 94.0 after the course (p = 0.0007). The clinical quiz scores improved over the 3 time points from 9.91 to 11.9, and 12.3, respectively. At the end of the in-person surgical week, 100% of respondents stated that they had improvement in knowledge and 92% considered the knowledge sufficient to change their clinical practice. In surveying the persistent obstacles to translating knowledge gained through blended learning to clinical practice, the top responses were constraints in personnel and cost of implants at their home institution. Conclusion: The blended learning approach in a pediatric spine deformity program is effective, feasible, and shows a statistically significant change in participants' confidence and knowledgebase in these complex pathologies. Our results are limited due to the small sample size. Future studies will evaluate larger number of participants in the post-COVID era and translation to other areas of spine surgery, such as minimally-invasive surgery.

2.
Corrosion Management ; - (165):31-33, 2022.
Article in English | Scopus | ID: covidwho-1929340
3.
Kuwait Journal of Science ; : 14, 2021.
Article in English | Web of Science | ID: covidwho-1819166

ABSTRACT

The first case of COVID-19 in Kuwait was reported on February 24, 2020. There is a need to develop a prediction model for estimating this epidemic size. In this study, we aimed to develop and compare several prediction models using real-time data of COVID-19 from February 24 to June 12, 2020. We modeled the uncertainty and non-stationary real-time data of COVID-19 cases using a multilayer model with different decomposition techniques. We applied our proposed hybrid methodology to predict COVID-19 cases in Kuwait. We further evaluated the performance of the novel hybrid model with others using mean relative error, mean absolute error, and mean square error. We found that our proposed hybrid approach performed better than others for predicting COVID-19 cases.

4.
Impact of Infodemic on Organizational Performance ; : 41-55, 2021.
Article in English | Scopus | ID: covidwho-1810482

ABSTRACT

The 21st century has been fighting against COVID-19, an infection caused by a virus SARS CoV-2. On 30th January 2020, the World Health Organization stated this condition as an international health emergency. Furthermore, on March 11, 2020, it was declared a global pandemic. The pandemic COVID-19 destroyed the health systems at a large scale and the businesses globally. Service, as well as manufacturing industries, faced significant challenges during this pandemic situation of COVID-19. Infodemic is one of the biggest challenges that creates severe problems for the business community. In such circumstances, businesses have to adopt unique business strategies to sustain and gain a competitive edge. The current study evaluates different business strategies like digital servitization, travel insurance, skunkworks structural approach, black swan, etc. adopted by different service sectors, based on a systematic review approach. Mostly, the research paradigm is focused on the aviation industry, and less attention is given to other service sectors like education, banking, etc. © 2021, IGI Global.

5.
European Respiratory Journal ; 58:2, 2021.
Article in English | Web of Science | ID: covidwho-1707679
6.
Kidney International Reports ; 7(2):S54, 2022.
Article in English | EMBASE | ID: covidwho-1705566

ABSTRACT

Introduction: Proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) is a rare form of PGN that mimics immune-complex (IC) GN by light microscopy (LM), but shows monoclonal IgG deposits by immunofluorescence (IF). PGNMID often presents with membranoproliferative (MPGN) pattern or endocapillary hypercellularity. Focal crescents are not uncommon in PGNMID, but diffuse crescentic involvement is very rare. Methods: 78-year-old man with a history of hypertension and multiple cardiovascular comorbidities presented with weakness, dizziness, and anorexia, and was found to have severe hypertension and acute kidney injury with serum creatinine of 12 mg/dl (baseline 1 mg/dl). He was a chronic smoker and alcoholic. He reported productive cough with scanty whitish sputum, but denied hemoptysis. Urine analysis showed marked proteinuria, hematuria, and leukocyturia. Renal ultrasound revealed bilateral decrease corticomedullary differentiation without obstruction. Hemodialysis was initiated. Imaging showed bilateral upper lobe pneumonia with concerns for alveolar hemorrhages. Serology for complements, ANA, dsDNA, ANCA, Hepatitis B and C, Covid19 was negative. Kappa/lambda free light chain ratio was normal. SPEP, UPEP and immunofixation were negative for paraproteinemia. Renal biopsy showed diffuse crescentic and endocapillary PGN with MPGN features, and linear monoclonal IgG3-kappa immune deposits. Given the lack of clinical evidence of cryoglobulinemia and presence of immune-type electron dense deposits without organized substructures by EM, the findings were most consistent with PGNMID. However, the unusual biopsy presentation raised concerns for possible concurrent anti-GBM disease. Subsequently, Solu-Medrol was started followed by prednisone 1 mg/kg. He received 2 sessions of plasmapheresis before anti-GBM serology returned negative. Bone marrow biopsy revealed monoclonal B-cell lymphocytosis with CLL phenotype. Unfortunately, the patient developed Covid19 infection, and passed away before receiving further treatment. [Formula presented] Results: PGNMID is a rare form of renal involvement by monoclonal immunoglobulin deposition that mimics ICGN on renal biopsy. Nephrotic range proteinuria, hematuria and renal insufficiency are usual presentation. Cases of PGNMID classically show IgG3k, in a granular glomerular capillary wall, mesangial, and occasionally subepithelial distribution. By EM, these deposits appear granular typical of ICGN which lack organized substructure. The predominant LM patterns are MPGN and endocapillary hypercellularity. Less frequently focal crescents may be present, but diffuse crescentic involvement is especially rare (~5%). In our case, the diffuse cellular crescents and semilinear to linear GBM staining was unusual. Together with the clinical presentation, the findings prompted concerns for a concomitant Goodpasture syndrome, but anti-GBM antibody returned negative. The pathogenesis is still unclear, but some authors suggest infection as a possible trigger for crescentic transformation in PGNMID. The presence of crescents seem to confer a poorer prognosis and associated with progression to ESRD. Conclusions: Our case is a unique presentation of PGNMID in a patient who presented with clinical and pathologic features concerning for Goodpasture syndrome. PGNMID can rarely present with diffuse crescents and IF findings similar to anti-GBM nephritis in a patient with RPGN. No conflict of interest

7.
Journal of King Saud University Science ; 33(8):11, 2021.
Article in English | Web of Science | ID: covidwho-1655256

ABSTRACT

The coronavirus disease spread out rapidly in China and then in the whole world. Kuwait is one of those countries which are positively affected by this pandemic. Objective: The current study aims to provide an appropriate and novel framework for the analysis of the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infected patient & rsquo;s counts and rate of change in these counts with respect to time. Therefore, we considered the number of SARS-CoV-2 patients, i.e., confirmed cases, deaths, and recover-ies for Kuwait, ranging from the 24th of February 2020 to the 25th of August 2020. Method: Here, we used the Markov Chain Monte Carlo (MCMC) simulation methods for the data analysis of SARS-CoV-2 to develop the Bayesian analysis of the Non-Homogeneous Poisson Process (NHPP). For this purpose, we used the two unique models of NHPP: the linear intensity function and the power law process. The dis-crimination methods are also discussed to select a better model for daily basis data of confirmed cases, deaths, and recoveries of SARS-CoV-2 patients. The appropriate model is selected based on the Deviance Information Criteria (DIC). Results: The value of DIC indicates that the power-law process performs better than the linear intensity functions for estimating and presenting all the study variables. The current study explored the usefulness and significance of the proposed research framework to analyze the SARS-CoV-2 new confirmed cases, recoveries, and deaths in a specific area. Conclusion: The findings of the study will be helpful for the health organizations or authorities to develop the approaches based on the current resources and situations due to the pandemic. The provided framework could be beneficial in analyzing the second and third layers of COVID-19 in the area. The analysis of the counts for each study variable and for each variable a comparative analysis of all the three layers is the aim of our future study. (c) 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

8.
International Transaction Journal of Engineering Management & Applied Sciences & Technologies ; 12(6):8, 2021.
Article in English | Web of Science | ID: covidwho-1304895

ABSTRACT

The coronavirus (Covid-19) has become a major cause of huma morbidity and mortality due to its transmitted mode in human beings. The public must follow precautionary practices to protect themselves from this world pandemic. Due to a lack of public practices, knowledge, and sensitivity, this transmitted disease suffers a large number of new cases around the world. This study examines the public's practices, knowledge, an sensitivity related to the Covid-19 in the Gilgit-Baltistan Pakistan area. We applied the exploratory methodology by reviewing the secondary data sources. We survey to collect the data and present the empirical evidence. We distributed five hundred questionnaires via the online and face-to-face approach and received 382 valid responses. The received data were analyzed by using descriptive statistics and a chi-square test. The empirical results indicate that majority of respondents are conscious and aware of the Covid-19 and moderately taking precautionary measures such as social distancing, washing hands, wearing the mask, avoid to handshaking/hug and avoidin: unnecessary traveling. It has been observed that participants are well aware of the sensitivity and the belief that the Covid-19 causes harm, changes expenditure life, exhausted, nervous, lonely, and fear for their individual life. Respondents have trust in social confidence and the roles of electronic media information regarding taking precautionary measures against the covid-19. Inversely, people have not to trust economic and safety measures taken b the government to control the Covid-19 pandemic. (C) 2021 INT TRANS J ENG MANAG SCI TECH.

10.
Lung Cancer ; 156:S12-S13, 2021.
Article in English | Web of Science | ID: covidwho-1274010
11.
Journal of Pakistan Association of Dermatologists ; 30(4):695-698, 2020.
Article in English | EMBASE | ID: covidwho-1250666

ABSTRACT

Telogen effluvium is temporary hair shedding after experiencing huge amount of stress in the form of trauma, shock or illness. We present 2 patients with excessive hair fall around 2 to 3 months after getting coronavirus infection.

12.
Journal of Allergy and Clinical Immunology ; 147(2):AB243-AB243, 2021.
Article in English | Web of Science | ID: covidwho-1148659
13.
Journal of Evolution of Medical and Dental Sciences-Jemds ; 9(52):3998-4002, 2020.
Article in English | Web of Science | ID: covidwho-1055303

ABSTRACT

Coronavirus disease (COVID-19) is an acute respiratory illness caused by a highly contagious novel coronavirus creating catastrophe globally. With no specific treatment and approved vaccine for COVID-19 till date, the practice of social distancing, preferably called physical distancing and staying home has been adopted as a part of the prevention and control strategy against the spread of 2019 -nCoV infection-causing COVID-19. But the implementation, extension and repetition of the lockdowns creates various threats not only on the economy but also on the psychosocial and behavioural changes in general. This article critically discusses the positive effects of lockdown along with its adverse possible outcomes or effects. The adverse effects experienced are multidimensional like psychosocial, mental and economical. The recent insurgence of COVID-19 cases, shortage of intensive care ventilators, quarantine, and ill effects of lockdown have led to depression, anxiety, insomnia, fear and insecurity in the common man. Worst ever economic recession has been noticed after COVID-19 lockdown. Consumer spending and buying power have also reduced significantly in all sectors. The looming crisis in developing nations is predicted to devastate economies disproportionately and ramp up inequality in such nations. This lockdown has pushed millions of people in various countries to no work, no income and hunger. The positive effects like reduction in air pollution, better lifestyle are also observed. The reduction in soil, water and air pollution is eventually helpful to live a healthy life. People are following proper hand washing practices, practicing respiratory etiquettes and maintaining proper personal hygiene and have embraced health promotion and disease prevention measures seriously. Traffic volume and street crimes have also been reported going down. Education has become digitalized and affordable. Family members are spending time with each other and developing gratitude towards their loved ones. Food waste control is critical. This lockdown has improved the food shopping performances in some places and a positive behavioural change for the prevention of food wastage is expected in other countries also. Lockdown reduces the reproduction of coronavirus, i.e., to reduce people having confirmed infection and treated as a case. The goal is to keep the reproduction number 'R' below one (R < 1), through mitigation & suppression. Embracing health promotion measures and practicing social responsibility is the need of the hour. However, policymakers should strive for maintaining a balance in measures in order to reduce the devastation of economies apart from safeguarding the health of the people.

14.
Annals of King Edward Medical University Lahore Pakistan ; 26:104-106, 2020.
Article in English | Web of Science | ID: covidwho-977875
15.
Journal of Pakistan Association of Dermatologists ; 30(1):181-189, 2020.
Article in English | EMBASE | ID: covidwho-846092

ABSTRACT

The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and the disease it causes, termed coronavirus disease 2019 (COVID‐19), has rapidly swept across the world since its first known human manifestation on December 8, 2019. Confirmed cases are present in over 160 countries. Patients of COVID-19 infection present with diverse cutaneous manifestations seen in 0.2% to 20% of patients. This article summarizes different dermatological manifestations in patients with COVID-19 through literature review using Google Scholar, Sci Hub, PubMed and other online review articles. Case reports, case series and other studies which mentioned cutaneous manifestations in the patients with COVID-19 infection were added. The most common cutaneous manifestation of COVID-19 was found to be maculopapular (morbilliform) exanthem. Papulovesicular rash, urticaria, painful acral red purple papules (COVID toes), livedo reticularis and petechiae were other presentations. Majority of lesions were localized on the trunk;however, involvement of the hands and feet was also noted. Cutaneous involvement usually followed the respiratory symptoms;nonetheless, in a minority, it preceded systemic features. Majority of the studies failed to report any correlation between COVID-19 severity and skin lesions. Cutaneous manifestations may help in early diagnosis of disease and prompt treatment of COVID-19.

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