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1.
Non-conventional in English | [Unspecified Source], Grey literature | ID: grc-750350

ABSTRACT

A middle-aged man with obstructive sleep apnea who had been treated with continuous positive airway pressure (CPAP) developed COVID-19. An analysis of airflow records from the CPAP machine revealed a rise in his respiratory rate on the night before the onset of COVID-19-related symptoms, while his nocturnal respiratory rate had been stable during the 18-month period prior to the presently reported episode. The present case suggests that a rise in respiratory rate detected using CPAP machine data could be an important sign of impending acute illness, such as COVID-19. Studies to elucidate the usefulness of this method are warranted.

2.
Respirol Case Rep ; 9(5): e00744, 2021 May.
Article in English | MEDLINE | ID: covidwho-1160366

ABSTRACT

A 78-year-old Japanese woman with no smoking history suffered from near-fatal coronavirus disease 2019 (COVID-19) requiring four-week invasive mechanical ventilation, with subsequent radiological features of pulmonary fibrosis. Although methylprednisolone gradually improved her respiratory condition, her oxygenation and exercise tolerance had drastically deteriorated, necessitating high-flow nasal cannula oxygen therapy. In parallel with tapering systemic steroid, the patient was treated with nintedanib. Three months later, the patient was able to walk with a walking aid using oxygen at 4 L/min. The present case is an indication that nintedanib might provide a novel therapeutic approach for managing post-COVID-19 fibrosis, although further studies are warranted.

3.
J Clin Sleep Med ; 16(10): 1811-1813, 2020 10 15.
Article in English | MEDLINE | ID: covidwho-1005004

ABSTRACT

None: A middle-aged man with obstructive sleep apnea who had been treated with continuous positive airway pressure developed COVID-19. An analysis of airflow records from the continuous positive airway pressure machine revealed a rise in his respiratory rate on the night before the onset of COVID-19-related symptoms, while his nocturnal respiratory rate had been stable during the 18-month period prior to the presently reported episode. The present case suggests that a rise in respiratory rate detected using continuous positive airway pressure machine data could be an important sign of impending acute illness, such as COVID-19. Studies to elucidate the usefulness of this method are warranted.


Subject(s)
Betacoronavirus , Continuous Positive Airway Pressure/statistics & numerical data , Coronavirus Infections/diagnosis , Coronavirus Infections/physiopathology , Pneumonia, Viral/diagnosis , Pneumonia, Viral/physiopathology , Respiratory Rate/physiology , Sleep Apnea, Obstructive/therapy , COVID-19 , Humans , Male , Middle Aged , Pandemics , Polysomnography/methods , SARS-CoV-2
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