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1.
EuropePMC; 2020.
Preprint in English | EuropePMC | ID: ppcovidwho-317163

ABSTRACT

Background: Gastrointestinal endoscopy (GIE) is useful for the early detection and treatment of many diseases;however, GIE is considered a high-risk procedure in the coronavirus disease 2019 (COVID-19) pandemic era. This study aimed to explore the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positivity in saliva and gastric and intestinal fluids to which endoscopy medical staff are exposed.Methods: The study was a single-center cross-sectional study. From June 1 to July 31, 2020, all patients who underwent GIE at Yokohama City University Hospital endoscopy center were registered. All patients provided 3 ml of saliva. For upper GIE, 10 ml of gastric fluid was collected through the endoscope. For lower GIE, 10 ml of intestinal fluid was collected through the endoscope. The primary outcome was the positive rate of SARS-CoV-2 in saliva and gastric and intestinal fluids. We also analyzed serum-specific antibodies for SARS-CoV-2 and patients’ background information.Findings: A total of 783 samples (560 upper GIE and 223 lower GIE samples) were analyzed. Polymerase chain reaction (PCR) on saliva samples did not show any positive results in either upper or lower GIE samples. However, 2.0% (16/783) of gastrointestinal fluid samples tested positive for SARS-CoV-2. No significant differences in age, sex, purpose of endoscopy, medication, or rate of antibody test positivity were found between PCR positive and PCR negative cases.Interpretation: Asymptomatic patients, even those with no detectable virus in their saliva, had SARS-CoV-2 in their gastrointestinal tract. Endoscopy medical staff should be aware of infection when performing procedures.Trial Registration: The study was registered in the University Hospital Medical Information Network Clinical Trials Registry as UMIN000040587. Funding: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.Declaration of Interests: The authors declare that they have no conflicts of interests.Ethics Approval Statement: The institutional review board at YCU Hospital approved this prospective study on May 17, 2020 (approval number: B200500054). Written consent for participation in the study was obtained from all patients.

2.
Journal of Information Systems & Operations Management ; 15(2):156-164, 2021.
Article in English | ProQuest Central | ID: covidwho-1678825

ABSTRACT

One of the largest real estate developers in Japan, Mitsubishi Real Estate Co., Ltd. has been going through a series of transformation initiatives in talent operations and organizational architecture. This paper illustrates the organizational efforts behind the corporate initiatives of developing a learning culture sustained by cognitive technology across the business. Furthermore, the authors have analyzed the organizational impact of various initiatives geared at enhancing organizational agility at Mitsubishi Real Estate Co., Ltd. during the Covid-19 pandemic in Japan.

3.
Revista de Management Comparat International ; 22(2):193-203, 2021.
Article in English | ProQuest Central | ID: covidwho-1335532

ABSTRACT

The negative impact of the Covid-19 pandemic on the world economy has been broadly researched and documented. In Japan, however, the Covid-19 pandemic brought along a series of transformation opportunities to corporates, government, and public education. This paper illustrates the organizational efforts of transforming legacy talent operations and organizational architecture at one of Japan 's largest software development businesses, Intec Inc. throughout the Covid-19 pandemic. Furthermore, the authors have also analyzed the impact of cognitive technology on organizational culture and global talent operations.

4.
Dig Endosc ; 34(1): 96-104, 2022 Jan.
Article in English | MEDLINE | ID: covidwho-1132881

ABSTRACT

OBJECTIVES: Gastrointestinal endoscopy (GIE) is useful for the early detection and treatment of many diseases; however, GIE is considered a high-risk procedure in the coronavirus disease 2019 (COVID-19) pandemic era. This study aimed to explore the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positivity in saliva and gastrointestinal fluids to which endoscopy medical staff are exposed. METHODS: The study was a single-center cross-sectional study. From June 1 to July 31, 2020, all patients who underwent GIE at Yokohama City University Hospital were registered. All patients provided 3 mL of saliva. For upper GIE, 10 mL of gastric fluid was collected through the endoscope. For lower GIE, 10 mL of intestinal fluid was collected through the endoscope. The primary outcome was the positive rate of SARS-CoV-2 in saliva and gastrointestinal fluids. We also analyzed serum-specific antibodies for SARS-CoV-2 and patients' background information. RESULTS: A total of 783 samples (560 upper GIE and 223 lower GIE samples) were analyzed. Polymerase chain reaction (PCR) on saliva samples did not show any positive results in either upper or lower GIE samples. However, 2.0% (16/783) of gastrointestinal fluid samples tested positive for SARS-CoV-2. No significant differences in age, sex, purpose of endoscopy, medication, or rate of antibody test positivity were found between PCR positive and PCR negative cases. CONCLUSIONS: Asymptomatic patients, even those with no detectable virus in their saliva, had SARS-CoV-2 in their gastrointestinal tract. Endoscopy medical staff should be aware of infection when performing procedures. The study was registered as UMIN000040587.


Subject(s)
COVID-19 , SARS-CoV-2 , Cross-Sectional Studies , Endoscopy, Gastrointestinal , Humans , Japan/epidemiology , Prevalence , Prospective Studies , Saliva
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