Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 8 de 8
American Journal of Respiratory and Critical Care Medicine ; 205:2, 2022.
Article in English | English Web of Science | ID: covidwho-1880122
British Journal of Surgery ; 108:1, 2021.
Article in English | Web of Science | ID: covidwho-1539394
British Journal of Surgery ; 108:216-216, 2021.
Article in English | Web of Science | ID: covidwho-1539381
Critical Care Medicine ; 49(1):97-97, 2021.
Article in English | Web of Science | ID: covidwho-1326437
British Journal of Surgery ; 108(SUPPL 2):ii21, 2021.
Article in English | EMBASE | ID: covidwho-1254452


Background: The United Kingdom now has one of the highest death rates from COVID 19, with over 40,000 deaths (1). It has been posited that the identification of care workers with immunity or increased resistance could be important in developing future strategies. Method: This was a retrospectively conducted survey of general surgical staff at a tertiary surgical unit. Results: We surveyed 215 staff that had undergone antibody testing. Of the 175/215 who reported contact with COVID-19 positive patients, 6/ 215 had a positive PCR result and 15/215 reported a positive antibody test. Only 3/6 that had a positive PCR test demonstrated antibodies. Conclusions: Our immunity rate of 7% is extremely low and is concerning especially in respect of the anticipated herd immunity which would mitigate many of the issues presently being confronted and it is likely to be many months at least before this makes realistic contribution. Continued testing for the presence of COVID-19 antibodies will contribute to crucial seroprevalence data that can be used by public health bodies whose advice will necessarily evolve as increasing data sets become available.

Critical Care Medicine ; 49(1 SUPPL 1):97, 2021.
Article in English | EMBASE | ID: covidwho-1193910


INTRODUCTION: Coronavirus disease 2019 (COVID-19) is a multisystem disease. It can affect the central and peripheral nervous systems. Neurological manifestations at the time of disease presentation may have severe outcomes of COVID-19. The objective of our study is to evaluate the outcomes of hospitalized COVID-19 patients admitted in the intensive care unit who presented with neurological symptoms. METHODS: This is a multi-center, retrospective, and observational study of hospitalized COVID-19 patients in the city of Louisville, Kentucky, and southern Indiana region from March 10, 2020 to June 20, 2020. Patients were included in this analysis if they were: tested positive for COVID-19 by reverse transcriptase-polymerase chain reaction and admitted to the intensive care unit (ICU) in one of the nine hospitals in Louisville, Kentucky. Patients were considered to have a neurological symptom if one of the following clinical features was present during admission: 1) headache 2) dizziness 3) confusion 4) anosmia 5) ageusia and 6) altered mental status. Baseline characteristics and outcomes were compared using t-tests of means for continuous data, and t-test of proportions for categorical data. P-values < 0.05 was considered statistically significant. RESULTS: Out of 700 hospitalized COVID-19 patients in the study, 231 were admitted to ICU. Among 231 ICU patients, 92 (39.82%) patients had neurological symptoms at the presentation. Among the patients admitted to ICU, those who presented with neurological symptoms have higher mortality than those who had no neurological symptoms at presentation (50% vs 30%, p=0.003). In addition, ICU patients who presented with neurological symptoms had a higher rate of cardiac arrest (16% vs 2%, p<0.001) and cerebrovascular accident (7% vs 1%, p=0.034) during hospitalization in comparison to ICU patient without neurological symptoms at presentation. CONCLUSIONS: Our study demonstrated that among the patients admitted in ICU, patients who presented with neurological symptoms have higher mortality than those without neurological symptoms. In addition, ICU patients have a higher rate of cardiac arrest and cerebrovascular accidents if they presented with neurological symptoms.