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1.
Pakistan Armed Forces Medical Journal ; 71(5):1732-1735, 2021.
Article in English | Scopus | ID: covidwho-1515776

ABSTRACT

Objective: To explore the use of therapeutic plasma exchange as adjunctive therapy in COVID-19 patients with and without diabetes mellitus. Study Design: Prospective, observational study. Place and Duration of Study: Pakistan Emirates Military Hospital Rawalpindi, from Jan to Feb 2021. Methodology: A total of 90 male patients with laboratory-confirmed coronavirus infection were selected based on our inclusion criteria and their management and outcomes were recorded. The data were analyzed using SPSS-22 and Microsoft Excel. Results: The mortality rate was lower in patients who received 1 or more sessions of plasma exchange compared to those who did not receive plasma exchange (7.5% vs 12%). A lower mortality rate was seen in patients without diabetes who received therapeutic plasma exchange in addition to standard therapy compared to patients who received standard therapy alone (0 vs 14.82%, p=0.112). In patients with diabetes, a higher mortality rate was found in the group that had received therapeutic plasma exchange in addition to standard therapy instead of standard therapy alone (20% vs 8.7%, p=0.365). Conclusion: Overall our study supports the use of therapeutic plasma exchange in COVID-19 patients. However, although statistically insignificant, there appears to be a higher mortality rate in patients with diabetes who received therapeutic plasma exchange in addition to standard therapy. As such, we recommend further investigation of this aspect. © 2021, Army Medical College. All rights reserved.

2.
Open Access Macedonian Journal of Medical Sciences ; 9(A):532-534, 2021.
Article in English | EMBASE | ID: covidwho-1362637

ABSTRACT

BACKGROUND: COVID-19 is resulted from severe acute respiratory syndrome coronavirus 2, which initiated in China in December 2019. Parasites are efficient immune modulators because their ability to stimulate an immune response in infected persons. AIM: This study aims to detect if there is a probable relationship between intestinal parasitic infections and COVID-19. METHODS: Ninety patients consulted at Al-Kindy Teaching Hospital (Al-Shifa center) from October 2020 till April 2021, confirmed infection with COVID-19 by PCR. Stool examination was done for detecting intestinal parasites. RESULTS: From 90 patients, males were 63 (70%), with median age 32 years, while females were 27 (30%), with age 24–44 years. Asymptomatic patients were 8.1 (9%), patients with moderate symptoms 22.5 (25%) cases, while the rest were 59.4 (66%) cases who required enter to the intensive care unit, with symptoms including cough (80%), dyspnea (74%), fever (56%), headache (43%), chest pain (37%), sore throat (35%), myalgia (32%), diarrhea (27%), and hemoptysis (3%). CONCLUSION: There is inverse relationship between parasitic infection and COVID-19 infections, and it is significant to understand the action between parasites and microbiome, also its function in COVID-19 pathogenicity.

3.
13th ACM SIGCHI Symposium on Engineering Interactive Computing Systems, EICS 2021 ; : 6-11, 2021.
Article in English | Scopus | ID: covidwho-1280489

ABSTRACT

Mental health conditions pose a major challenge for individuals, healthcare systems and society-and the COVID-19 pandemic has likely worsened this issue. According to the Mental Health Foundation of New Zealand, one in five people will develop a serious mood disorder, including depression, at some time in their life. Co-designed solutions to increase resilience and well-being in young people have specifically been recognised as part of the National Suicide Prevention Strategy and the New Zealand Health Strategy. Virtual Reality (VR) in mental health is an innovative field. Recent studies support the use of VR technology in the treatment of anxiety, phobia, and pain management. However, there is little research on using VR for supporting, treating and preventing depression. There is also very little work done in offering an individualised VR experience to improve mental health. In our earlier work, we presented iVR, a novel individualised VR experience for enhancing peoples' self-compassion, and in the long run, their mental health, and described its design and architecture. In this paper, we outline the results of a feasibility study conducted recently. Most participants believed introducing elements of choice within iVR enhanced their user experience and that iVR had the potential to enhance people's self-compassion. We also approached seven mental health professionals for feedback, who felt that introducing elements of choice within iVR would increase their knowledge of clients. Our contribution can pave the way for large-scale efficacy testing, clinical use, and cost-effective delivery of intelligent individualised VR technology for mental health therapy in future. © 2021 ACM.

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