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1.
Advances in Human Biology ; 12(1):22-26, 2022.
Article in English | Web of Science | ID: covidwho-1917944

ABSTRACT

Introduction: Platelet-rich fibrin (PRF) is a term for autologous platelet concentrates generated from the patient's own blood (PRF). PRF and its derivatives (L-PRF, A-PRF, i-PRF) have been used for delicate tissue restoration in a variety of dental procedures. The quantity of leucocytes and other growth factors in PRF of healthy and post-COVID-19 people differs, according to the literature, and these influence wound tissue healing. Materials and Methods: Thirty healthy volunteers and 30 post-COVID-19 volunteers (age range 24-60 years). For PRF preparation, a REMI PR-23 table centrifuge and a blood collection kit consisting of a 19G needle and 10 ml blood collection tubes were used. The analysis was performed by dividing the subject groups into three test groups (Group 1 - post-COVID-19, 0-30 days;Group 2 - post-COVID-19, 31-90 days;Group 3 - normal patients). Group 1, 2 and 3 consisted of 23, 7 and 30 patients, respectively. Results: The result was statistically significant between the normal and posted COVID-19 patient groups (P = 0.00). Not much statistical significance was found between post-COVID-19 patients from 0-30 days to 31-90 days (P = 0.370). Considering the limitations of the study, our findings imply that typical patients' PRF clots or membranes comprise the majority of platelets and half of the leucocytes present in the first blood collection. Conclusion: Within the fibrin network, platelet growth factors are stuck, but the PRF clot or membrane of the post-COVID-19 patients contains a reduced/negligible number of leucocytes. Thus, the growth factors which is released are also less. Therefore, usage of PRF in post-COVID-19 patients for periodontal regenerative therapies should be avoided, at least for the first 60 days, to replenish the reduced leucocyte count and growth factors in the blood.

2.
Global Mental Health ; 2022.
Article in English | EMBASE | ID: covidwho-1882692

ABSTRACT

Objectives: In addition to risking their physical well-being, frontline physicians are enduring significant emotional burden both at work and home during the COVID-19 pandemic. This study aims to investigate the levels of anxiety and depressive symptoms and to identify associated factors among Bangladeshi physicians during the COVID-19 outbreak. Methods and design: A cross-sectional study using an online survey following a convenience sampling technique was conducted between April 21 and May 10, 2020. Outcomes assessed included demographic questions, COVID-19 related questions, and the Hospital Anxiety and Depression Scale (HADS). Results: The survey was completed by 412 Bangladeshi physicians. The findings revealed that, in terms of standardized HADS cut-off points, the prevalence of anxiety and depressive symptoms among physicians was 67.72% and 48.5% respectively. Risk factors for higher rates of anxiety or depressive symptoms were: being female, physicians who had experienced COVID-19 like symptoms during the pandemic, those who had not received incentives, those who used self-funded personal protective equipment (PPE), not received adequate training, lacking perceived self-efficacy to manage COVID-19 positive patients, greater perceived stress of being infected, fear of getting assaulted/humiliated, being more connected with social media, having lower income levels to support the family, feeling more agitated, less than 2 hours of leisure activity per day and short sleep duration. All these factors were found to be positively associated with anxiety and depression in unadjusted and adjusted statistical models. Conclusions: This study identifies a real concern about the prevalence of anxiety and depressive symptoms among Bangladeshi physicians and identifies several associated factors during the COVID-19 pandemic. Given the vulnerability of the physicians in this extraordinary period whilst they are putting their own lives at risk to help people infected by COVID-19, health authorities should address the psychological needs of medical staff and formulate effective strategies to support vital frontline health workers.

3.
Bangladesh Journal of Infectious Diseases ; 8(2):57-63, 2021.
Article in English | CAB Abstracts | ID: covidwho-1865446

ABSTRACT

Background: IPC knowledge and practice can shield HCWs from being infected or even worse.

4.
International Management Conference, IMC 2021 ; : 101-116, 2022.
Article in English | Scopus | ID: covidwho-1826310

ABSTRACT

COVID-19 has made a big impact worldwide due to its tendency to rapidly spread. All nations across the world have taken all possible measures to minimize its effect and to bring life back to normal. Vaccine for COVID-19 has come into the market but the hunt for a better vaccine is still going on. The community is showing mixed responses towards the acceptance of the vaccine despite the unprecedented efforts that are being taken globally to develop a vaccine against COVID-19. Since the advent of COVID-19 and till the vaccine is being given to the people, social media has been on the forefront of spreading news related to COVID-19 and vaccination. Social media has created the perception among people related to every situation during the pandemic, therefore the current study reveals the impact of social media on people and their reaction to the situation. The objective of the study was to assess the influence of social media with respect to the awareness and behavioural change among people and also examining the influence on acceptance of the vaccine. The data was collected from social media platforms and using quantitative methods. It was suggested that social media can encourage positive behavioural changes and it can also be used as powerful media tool to address social concern and to remove social dogma among people with regards to vaccination. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

5.
PubMed; 2020.
Preprint in English | PubMed | ID: ppcovidwho-333632

ABSTRACT

OBJECTIVES: In addition to risking their physical well-being, frontline physicians are enduring significant emotional burden both at work and home during the COVID-19 pandemic. This study aims to investigate the levels of anxiety and depressive symptoms and to identify associated factors among Bangladeshi physicians during the COVID-19 outbreak. METHODS AND DESIGN: A cross-sectional study using an online survey was conducted between April 21 and May 10, 2020. Outcomes assessed included demographic questions, COVID-19 related questions, and the Hospital Anxiety and Depression Scale (HADS). RESULTS: The survey was completed by 412 Bangladeshi physicians. The findings revealed that, in terms of standardized HADS cut-off points, the prevalence of anxiety and depressive symptoms among physicians was 67.72% and 48.5% respectively. Risk factors for higher rates of anxiety or depressive symptoms were: being female, physicians who had experienced COVID-19 like symptoms during the pandemic, those who had not received incentives, those who used self-funded PPE, not received adequate training, lacking perceived self-efficacy to manage COVID -19 positive patients, greater perceived stress of being infected, fear of getting assaulted/humiliated, being more connected with social media, having lower income levels to support the family, feeling more agitated, less than 2 hours of leisure activity per day and short sleep duration. All these factors were found to be positively associated with anxiety and depression in unadjusted and adjusted statistical models. CONCLUSIONS: This study identifies a real concern about the prevalence of anxiety and depressive symptoms among Bangladeshi physicians and identifies several associated factors during the COVID-19 pandemic. Given the vulnerability of the physicians in this extraordinary period whilst they are putting their own lives at risk to help people infected by COVID-19, health authorities should address the psychological needs of medical staff and formulate effective strategies to support vital frontline health workers. STHRENGHTS & LIMITATIONS OF THE STUDY: This study reports a novel and concerning findings on the prevalence of anxiety and depression symptoms with identification of several important associated factors among Bangladeshi physicians during the COVID-19 pandemic. The cross-sectional nature of the study design could not establish causal relationship between the dependent and independent variables. This study was carried out by conducting a web-based survey, which might generate sampling bias by excluding the physicians who do not have access to internet or inactive in social medias, and thus limit the generalizability of the findings.

6.
ICIC Express Letters ; 16(2):109-115, 2022.
Article in English | Scopus | ID: covidwho-1732607

ABSTRACT

This research aims to evaluate factors that could influence the intention of using video conferencing applications during the COVID-19 pandemic as a means for workers to work from home. The research model used in this study is the UTAUT model, with perceived risk and trust as extended variables. Data collection was carried out by distributing questionnaires. A total of 212 samples were then collected and analyzed using SEM-PLS. The results show that risk perception negatively affects intention to use but is not significant enough to inhibit actual use. It was also revealed that the influence of behavioral intention on the user behavior variable is the most positive and significant. © 2022 ICIC International. All rights reserved.

7.
Population Medicine ; 4(January), 2022.
Article in English | Scopus | ID: covidwho-1700662

ABSTRACT

INTRODUCTION Effective pandemic management requires understanding the level of community knowledge, attitudes of people, and preparedness towards COVID-19. This study aimed to assess gender differences regarding knowledge, attitudes and preparedness toward the COVID-19, among Bangladeshi adults. METHODS A cross-sectional survey was conducted March– April 2020 among 1050 Bangladeshi adults. A convenience sampling strategy was utilized, and the data were collected online through a self-administered questionnaire. Chisquared tests were used to identify the gender differences regarding knowledge, attitudes and preparedness towards COVID-19. RESULTS Respondents predominately used social media to inform themselves about COVID-19 (68.1%), and females used social media more than males (p<0.001). Females had higher levels of correct knowledge about staying home with sickness and symptoms to prevent the COVID-19 transmission (p=0.02). Males had a more negative attitude about staying out during the pandemic than females (p<0.001);men were less likely to take preventative measures than their female counterparts. Some people believed in misinformation like ‘COVID-19 can transmit via mosquitos’ (9.1%), and males had more incorrect knowledge regarding this (p<0.001). Moreover, 17.8% of the respondents thought that COVID-19 could spread in warm weather. CONCLUSIONS Males showed a higher tendency to believe the myths about COVID-19 than their female counterparts, which is alarming. Awareness programs should be emphasized, focusing on gender-specific pertinent information to ensure effective preventative measures. © 2022 Sultana M. S. et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non Commercial 4.0 International License. (http://creativecommons.org/licenses/by-nc/4.0)

8.
Jcpsp-Journal of the College of Physicians and Surgeons Pakistan ; 31(7):S152-S154, 2021.
Article in English | Web of Science | ID: covidwho-1573101

ABSTRACT

Review of literature on effectiveness of vitamin D in COVID-19 infection demonstrated a positive effect in COVID-19 patients. However, the studies are limited either due to small sample size or are conducted in a select subset of patients. Gaps on proofof-concept or a cause-effect relationship related to the use of vitamin D in COVID-19 infection still exist. COVID-19 related benefits of vitamin D have not been validated and are still hypothetical. Administration of high amounts of vitamin D, without clinical indication, could result in toxicity and harmful consequences. Large, multi-centre, placebo-controlled clinical trials in patients with varying severity of COVID-19 infection are needed to establish the role of vitamin D supplementation as an inexpensive therapeutic tool to fight the ongoing pandemic. Administration of vitamin D in already sufficient population should be held until concrete evidence is being established.

9.
Pakistan Journal of Medical and Health Sciences ; 15(10 October):2503-2505, 2021.
Article in English | EMBASE | ID: covidwho-1554433
10.
Infosys Science Foundation Series in Mathematical Sciences ; : 377-408, 2021.
Article in English | Scopus | ID: covidwho-1491039

ABSTRACT

In this work an attempt has been made to review the current state of arts in epidemiological modeling, assessment of predictive models as well as forecasting of new pathogen. The primary concern is the containment of the outbreak from wide spread of the disease among the whole population. This article also focuses for the development of management tools and techniques in decision making for policy makers that are based on scientific evidence. Moreover, the identification, detection and reporting for outbreak of an infectious disease particularly a new pathogen in timely manner is quite challenging and tedious. Apparently understanding and reporting of such events are commonly rely on statistical and mathematical tools and both these approaches commonly depend upon a priory estimates as well as some reliable data. For example: statistical models requires a sizable number of events to develop predictive models, which is impossible at the outset of an outbreak of the disease to collate enough number of samples. Whereas, the mathematical models are reliable as well as have better predictive behavior, but they also require better initial guess apart from some rigid constraints to fully satisfy the model’s assumptions. Apart from these issues, the other important features to study in epidemiology of the disease is how fast and quickly the scientific community promptly can pinpoint and able to address any causal factor which may suffice to account for the magnitude and severity of the epidemics of new pathogen that may have been taken place to any geographic locations. Hence in this work, first of all the SIR model (susceptible: S, infected: I, and recovered: R) will be outlined, as it is the most commonly used model in epidemiology of infectious diseases. Moreover, the applicability and utilization of R0 in public health domain especially adaptive policy with management tools will be developed for the healthcare workers as well as the higher management of healthcare facility. © 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

11.
Malaysian Journal of Medicine and Health Sciences ; 17(3):149-158, 2021.
Article in English | Scopus | ID: covidwho-1459764

ABSTRACT

Introduction: Coronavirus disease-2019 (COVID-19) was declared a global pandemic in March 2020, with 15 million people have been infected worldwide, and this number is increasing. Our study sought to assess the knowledge and practice of healthcare workers (HCWs) in a teaching hospital in Malaysia. Methods: This cross-sectional study was undertaken using online Google form links among HCWs. Knowledge and practice were assessed using a validated questionnaire. The analysis was performed with SPSS version 26. Factors associated with poor knowledge were analysed using multivariate analysis. Results: A total of 193 HCW responded to our online survey. Majority of our HCWs were female (74.1%) with a mean age of 32.5 years. We found 53 (27.5%) and 134 (69.4%) of our HCWs had good knowledge and good practice on COVID-19, respectively. Knowledge gap was identified in the symptomatology, investigation methods and management. Based on multiple logistic regression, determinants of poor knowledge scores were those work as medical attendants (aOR = 3.626;95% CI = 1.489, 8.834) and nurses (aOR = 4.107;95% CI = 1.175, 14.358). Conclusion: Around one-third and 70% of our HCWs have good knowledge and practice of COVID-19 infection respectively. Continuous, specifically targeted and updated medical education, need to be carried out to improve the knowledge and practice among our HCWs in order to keep abreast of the fast-moving pace of COVID-19 knowledge development. © 2021 UPM Press. All rights reserved.

12.
2021 ACM Designing Interactive Systems Conference: Nowhere and Everywhere, DIS 2021 ; : 1748-1764, 2021.
Article in English | Scopus | ID: covidwho-1327754

ABSTRACT

The global education landscape continues to be disrupted by COVID-19. The unique circumstances created by this crisis has led to unexpected opportunities to leverage innovative uses of technologies that can radically innovate education service delivery. We map out the context of Pakistan - a country where challenges pertaining to both access to education and quality learning predate the pandemic. A context largely under explored in design and HCI research. This paper presents insights from conversations with 21 stakeholders across 15 design activities, that were structured around speculative design proposals to collaboratively envision the future of education in Pakistan. The paper offers directions for the design of EdTech through a plural, and culturally rooted speculative discussion, highlighting (1) opportunities and considerations for localising design for education, and (2) reframing the value of education in Pakistan. © 2021 ACM.

13.
Journal of Clinical and Diagnostic Research ; 15(5):OD03-OD05, 2021.
Article in English | EMBASE | ID: covidwho-1227176

ABSTRACT

The current pandemic of Coronavirus Disease 2019 (COVID-19) has posted unprecedented challenges to the community of clinicians in various aspects, ranging from prompt and early diagnosis to preventing complications. What makes the challenge even tougher is to be able to distinguish between diseases presenting with similar complaints, especially in tropical regions, and yet be able to treat judiciously and give a targeted treatment. The level of difficulty escalates when a patient with Solid-Organ Transplant (SOT) on immunosuppressive therapy presents to the clinician as suspected COVID-19 along with a co-infection. Incidences like these carry an increased burden of higher morbidity and mortality, with or without immunosuppression, if not timely diagnosed and judiciously treated, thus heralding the need to be vigilant in the current pandemic. Thus, to the best of our knowledge, this was the first documented and successfully treated case of a patient with past history of Liver Transplant (LT) with Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pneumonia with co-existing Plasmodium vivax (P.vivax) malaria.

14.
Journal of Medicine ; 22(1):69-71, 2021.
Article in English | ProQuest Central | ID: covidwho-1060535

ABSTRACT

There are a number of gastrointestinal symptoms and complications of COVID-19. Asymptomatic increase in pancreatic enzymes and rarely symptomatic pancreatitis are observed in this disease. This article describes a 37-year-old male suffering from mildly symptomatic COVID-19 infection, who received tablet favipiravir for his management. His condition was improving, when he developed acute pancreatitis, diagnosed clinically, biochemically and also with help of abdominal ultrasound. When he developed this, all typical symptoms of COVID-19 were improved. As a result, role of favipiravir in the development of this pancreatitis was suspected.

15.
Journal of the American Society of Nephrology ; 31:306, 2020.
Article in English | EMBASE | ID: covidwho-984274

ABSTRACT

Background: During the initial phase of the SARS CoV-2 pandemic our institution had high rates of acute kidney injury (AKI) requiring renal replacement therapy (RRT). Nephrocheck (NC), a renal biomarker, indicating renal stress was the basis of a continuous quality improvement (CQI) program to identify patients at risk for AKI & RRT. Methods: Patients admitted from 4/17-5/15/2020 were all tested for SARS CoV-2. All positive patients ≥ 18 years old & with a creatinine <2.0 mg were tested with NC. Values ≥ 0.7 led to nephrology consults & utilization of a renal-protective strategy including monitoring volume status, scrutinizing nephrotoxic medications & urine studies. A 'Plan-Do-Study-Act' approach was used to increase utilization of NC and the resulting protocol for positive results. Intervention was biphasic with a follow up maintenance phase, each lasting 10 days. Phase 1 was adding NC to the SARS CoV2 admission order set & Phase 2 was educating hospitalist providers about using and interpreting NC to increase appropriate nephrology consults. Education was reinforced with protocol cards & reminders via encrypted text services. Additionally, intervention team members reviewed charts daily & reminded providers in real time. Results: In Phase 1, 58% of the SARS CoV-2 positive patients had a NC but only 48% of NC positive patients had a renal consult. In Phase 2, 79% of SARS CoV-2 positive patients had a NC with 80% of positive patients getting a renal consult. In the maintenance phase, 67% of SARS CoV-2 positive patients had NC with 59% of NC positive patients getting a renal consult. Conclusions: During our CQI project, efforts to mitigate severe AKI by using a biomarker-based alert for nephrology consultation saw the number of SARS CoV2 positive patients screened with NC & the number of positive NC patients seen by nephrologists rise significantly. Barriers to implementation included the weekly turn-over of house staff & a reliable alert system to ensure adequate screening. The multidisciplinary team reviewing charts and reminding hospitalists of the protocol also helped significantly but was difficult to sustain.

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