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J Chest Surg ; 2022.
Article in English | PubMed | ID: covidwho-2155636


BACKGROUND: Coronavirus disease 2019 (COVID-19) has been found to cause life-threatening respiratory failure, which can progress to irreversible lung damage. Lung transplantation can be a life-saving treatment in patients with terminal lung disease (e.g., acute respiratory distress syndrome caused by infection). This study aimed to present the clinical course and results after initial lung transplantation in patients with severe COVID-19 who did not recover even with optimal medical care. METHODS: From August 2019 to February 2022, this study enrolled 10 patients with COVID-19 (5 men;median age, 55.7 years) who underwent lung transplantation at a single center in Korea. All patients' characteristics, clinical pathway, overall survival, complications, and operative data were collected and analyzed. RESULTS: Veno-venous extracorporeal membrane oxygenation or an oxygenator in a right ventricular assist device circuit was applied to 90% of the patients, and the median length of extracorporeal life support before operation was 48.5 days. There were no cases of mortality after a median follow-up of 372.8 days (interquartile range, 262.25-489 days). The major complications included the requirement for postoperative extracorporeal membrane oxygenation support in 2 cases (20%), re-transplantation in 1 case (10%), and re-exploration due to bleeding in 2 cases (20%). During the follow-up period, 3 out of 10 patients died. CONCLUSION: Excellent early outcomes were observed for patients who underwent lung transplantation. Thus, lung transplantation can be an effective and feasible treatment for patients with end-stage lung disease caused by COVID-19.

Journal of the Architectural Institute of Korea ; 38(8):3-14, 2022.
Article in Korean | Scopus | ID: covidwho-2056134


Working from home is increasing worldwide due to the spread of COVID-19, and the sudden telecommuting environment in existing residential spaces has caused a lot of inconvenience. This study deals with the variable system and space developed to support working from home in existing residences. The purpose of this study is to find a way to secure a flexible independent working from home space at any time, and to design a housing model using smart wall system. To achieve this, 1) Problem analyzed and requirements were derived of residential spaces for working from home, 2) A smart wall system was built for the realization of a flexible teleworking space at any time, and a plan was sought for its utilization. 3) A variable space was designed using a smart wall that varies in various ways. The smart wall presented in this study is a system that secures variable performance, IoT communication easiness, and information display performance while including furniture and devices so that a telecommuting space can be newly constructed. By using this, it was designed on a basic floor plan of an apartment of 84㎡, the size of a national house, and 5 ways to use it were derived, designed and simulated based on the scenarios for each space. In addition, in order to realize various variable spaces, it has implications that the variable space of a columnar structure should be a base structure. © 2022 Architectural Institute of Korea.