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Canadian Liver Journal ; 2022.
Article in English | Web of Science | ID: covidwho-2005842


BACKGROUND: Infection with chronic hepatitis C virus is a global public health concern. A recent study concluded that Canada is on track to achieve hepatitis C elimination goals set by the World Health Organization if treatment levels are maintained. However, recently a falling temporal trend in treatments in Canada was observed, with most provinces seeing a decrease before the global coronavirus pandemic. This study assesses the timing of elimination of hepatitis C in the 10 provinces of Canada. METHODS: Previously published disease and economic burden model of hepatitis C infection was populated with the latest epidemiological and cost data for each Canadian province. Five scenarios were modelled: maintaining the status quo, decreasing diagnosis and treatment levels by 10% annually, decreasing diagnosis and treatment levels by 20% annually, increasing them by 10% annually, and assuming a scenario with no post-coronavirus pandemic recovery in treatment levels. Year of achieving hepatitis C elimination, necessary annual treatments for elimination, and associated disease and economic burden were determined for each province. RESULTS: If status quo is maintained, Manitoba, Ontario, and Quebec are off track to achieve hepatitis C elimination by 2030 and would require 540, 7,700, and 2,800 annual treatments, respectively, to get on track. Timely elimination would save 170 lives and CAD$122.6 million in direct medical costs in these three provinces. CONCLUSIONS: Three of Canada's provinces-two of them most populous in the country-are off track to achieve the hepatitis C elimination goal. Building frameworks and innovative approaches to prevention, testing, and treatment will be necessary to achieve this goal.

Revista Cientifica Multidisciplinar RECIMA21 ; 2(8), 2021.
Article in Portuguese | CAB s | ID: covidwho-1548015


Objective: To list studies that show the relationship of long-term damage to the sense of smell in adult patients with COVID-19 (coronovirus disease), in order to facilitate access to information on the management of this sequel and thus address the problem. COVID-19, caused by SARS-CoV-2, emerged in the East Asian region and became a pandemic causing the death of millions of individuals. Fever, dyspnea, cough, arthralgia, myalgia, headache, rhinorrhea and diarrhea are the most prevalent symptoms, in addition to olfactory and taste changes, which commonly cause anosmia and dysgeusia. This literature review aims to list the relationships between long-term damage to smell in patients with Covid-19 and its possible treatment. Thus, we carried out a narrative review of the literature in the PUBMED database with the following keywords: "smell of loss";"Covid-19";"Chronic damage". Thus, we found seven articles, and two articles were discarded, the first for relating olfaction loss by COVID-19 in children only, a rare fact in this age group. And the second, for escaping the topic.

Revista Cientifica Multidisciplinar RECIMA21 ; 2(9), 2021.
Article in Portuguese | CAB Abstracts | ID: covidwho-1535202


Myopia is an ophthalmological abnormality prevalent among human beings, it is characterized by the formation of an image anteriorly to the retina, with the ciliary muscle at rest. We can list genetics and environment as conditioning factors of this pathology;in the meantime, this last factor has acquired great importance nowadays, in view of the growing exponential increase in the use of electronic screens. This literature review aims to list the relationships between myopia and the overuse of screens. In this context, it is necessary to review the main international publications on this health problem in children under 4 years of age. Thus, we carried out a literature review in the PUBMED database with the following keywords: "Myopia";"Use of Digital Devices";"children", "computer", "covid". Although the relationship between the pandemic and the repercussions for ophthalmic health proposed in this work is an extremely relevant topic, it is known that there is still a need for further studies.