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Adv Respir Med ; 89(1): 72-74, 2021.
Article in English | MEDLINE | ID: covidwho-1143743

ABSTRACT

A COVID-19 diagnosis is usually based on PCR detection of viral RNA in airway specimens in a patient with typical clinical fea-tures. Histological features of the COVID-19 lung disease are reported from autopsies. Transbronchial cryobiopsy (TBCB) is an evolving technique usually performed in the diagnosis of interstitial lung disease. We report a TBCB in a 76-year-old female patient who had repeatedly tested negative for SARS-CoV-2 infection. The pathological examination revealed the presence of interstitial pneumonia with lymphocytic infiltration. The qRT-PCR against SARS-CoV-2 from a pharyngeal swab was positive after performing the TBCB.


Subject(s)
Bronchoscopy/methods , COVID-19 Testing/methods , Cryosurgery/methods , SARS Virus/isolation & purification , Aged , Biopsy/methods , Clinical Laboratory Techniques , Female , Humans
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