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1.
Journal of Clinical Oncology ; JOUR(16):E18570-E18570, 40.
Article in English | Web of Science | ID: covidwho-2092662
2.
6th International Conference on Medical and Health Informatics, ICMHI 2022 ; JOUR: 309-314,
Article in English | Scopus | ID: covidwho-2088925

ABSTRACT

This study focused on the two health education effects of frequent handwashing with soap and wearing masks that can be maintained by individuals. According to the World Health Organization (WHO), as of March 13, 2022, the number of confirmed cases of new coronary pneumonia has exceeded 452 million, and the number of deaths due to the infection has exceeded 6 million. In addition to vaccine administration and new drug research and development, the implementation of health education is a comprehensive and important epidemic prevention policy. As the Covid-19 virus continues to mutate, the world is still under the threaten of the epidemic. This study takes Kampala, the capital of Uganda, Africa as the research object, to explore the effectiveness of the Ugandan government's health education on preventing the spread of COVID-19 in primary schools. © 2022 ACM.

4.
Pharmacoepidemiology and Drug Safety ; JOUR:626-626, 31.
Article in English | Web of Science | ID: covidwho-2083837
5.
Annals of Neurology ; JOUR:S183-S183, 92.
Article in English | Web of Science | ID: covidwho-2083836
6.
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10.
Chest ; 162(4):A1167, 2022.
Article in English | EMBASE | ID: covidwho-2060784

ABSTRACT

SESSION TITLE: COVID-19 Infections: Issues During and After Hospitalization SESSION TYPE: Original Investigations PRESENTED ON: 10/17/2022 01:30 pm - 02:30 pm PURPOSE: We present a retrospective study at one of the largest public, safety-net hospitals in the United States to highlight the importance of codifying the impact of COVID-19 disparities in marginalized populations. We used the following metrics to draw conclusions: patient demographics, vaccination status, comorbid conditions, length of stay (LOS), readmission rates, and clinical outcome. METHODS: For this retrospective study, we used Slicer Dicer software (Epic Verona, WI), an Epic self-service reporting tool, to query clinical data and identified a cohort of 9,040 patients ≥ 18 years old diagnosed with COVID-10 at Grady Memorial Hospital in Atlanta from 1/1/21 to 12/31/21. Statistical significance was defined as p<0.05. RESULTS: Of the 9,040 patients, 54.7% were female (4,942) and 45.3% were male (4,096). The cohort median age was 51 (range 18 – 100) and 80.5% were African American (7,278/9,040). Double-dose vaccination rate was only 24.5% (2,215/9,040). 38.3% of patients diagnosed with COVID-19 were admitted (3,467/9,040) and among these patients 3.0% were re-admitted (107/3,467). The most prevalent comorbidities were essential hypertension (45.2%), diabetes (21.7%), and asthma (13.2%). Patients with these comorbidities were more likely to be discharged as opposed to being admitted. Patients with the following comorbidities were more likely to be admitted: Pulmonary hypertension (70% admission rate), COPD (64.9%), heart failure (61.0%), cancer (60.8%), atrial fibrillation (57.1%). Median LOS from admission was 4 days and there was no statistical difference among different comorbidities. We found higher mortality in COVID-19 patients with cancer (12.9%), atrial fibrillation (12.6%), heart failure (11.1%), pulmonary hypertension (10.1%) and COPD (9.1%) compared to patients with diabetes (7.5%), hypertension (6.7%), HIV (4.8%), DVT/PE (4.6%), or asthma (2.7%). When examining overall mortality based on self- reported race, we found that African American patients had a statistically significant higher mortality compared to Caucasian patients (p-value= 0.00454). CONCLUSIONS: Current retrospective study, which included COVID-19 patients with different comorbidities showed that COVID-19 patients with pulmonary hypertension have worse clinical outcomes compared to other comorbid conditions. CLINICAL IMPLICATIONS: Our findings suggest the importance of investigating COVID-19 disparities in marginalized populations to better understand the impact in these communities. All individuals should be encouraged to get vaccinated against COVID-19, especially those found to be at high risk of severe illness such as pulmonary hypertension. In this retrospective study, we found higher hospital admission rate and worse outcomes in patients with cancer, atrial fibrillation, heart failure, and pulmonary hypertension, as well as higher mortality among the African American patient population. DISCLOSURES: No relevant relationships by nicolas bakinde No relevant relationships by Suvrat Chandra No relevant relationships by Michelle Lee no disclosure on file for Mario Ponce;

11.
Investigative Ophthalmology and Visual Science ; 63(7):2659, 2022.
Article in English | EMBASE | ID: covidwho-2057987

ABSTRACT

Purpose : Charles Bonnet syndrome (CBS) is characterised by visual hallucinations secondary to sight loss. Aside from sight loss, other risk factors associated with CBS include social isolation, loneliness, and post-traumatic stress. The health and lifestyle circumstances of visually impaired military veterans place this profile at an increased risk of developing CBS. The purpose of this study was to estimate the prevalence of CBS through an analysis of health records for members of a UK sight loss charity (Blind Veterans UK) and report experiences of CBS during the COVID-19 pandemic. Methods : A retrospective analysis and screening/filtering of military veterans' electronic membership records at Blind Veterans UK. Text analysis was used to identify CBS cases. A cross sectional survey of individuals with active CBS was used to measures patientreported features of hallucinatory experiences during the COVID-19 pandemic and perceived episode triggers. Results : Analysis was conducted on 4109 members of Blind Veterans UK. Following screening and exclusion of members with non-sight loss related hallucination risk factors (e.g., Alzheimer's disease), 532 members were identified as CBS cases, representing 12.9% (95% CI: 11.1%-14.7%) of the cohort. Forty-five individuals with CBS completed the survey. Loneliness during the pandemic was associated with changes in the nature of visual hallucinations (p=0.04). Individuals experiencing greater loneliness were, on average, older than those with no changes to their feelings of loneliness (p=0.03). Despite experiencing greater feelings of loneliness (67%), most individuals had not accessed support services. Conclusions : The relative high prevalence of CBS among visually impaired military veterans indicates that this cohort may be at greater risk of the condition. Approximately half of survey respondents experienced exacerbation of visual hallucinations during the COVID-19 pandemic, which may partly be explained by loneliness and/or environmental triggers.

12.
Taiwan Journal of Public Health ; 41(3):301-311, 2022.
Article in Chinese | Scopus | ID: covidwho-2056211

ABSTRACT

Objectives: The severity of the COVID-19 epidemic in 2021 in Taiwan doubled the workload of first-line acute- and critical-care nurses and increased their risk of infection. This study explored such nurses' work and personal lives to help hospitals develop auxiliary measures. Methods: This qualitative study interviewed fifteen nurses working in acute- and critical-care units. Results: Three themes were regarding the meaning of the nurses' work during the pandemic were identified: (a) keeping life stable, (b) fulfilling duties, and (c) recognizing self-worth. Four themes regarding the meaning of the nurses' personal lives were identified: (a) caring for families, (b) the impermanence of life and death, (c) doing good, and (d) seizing the day. Conclusions: During the pandemic, the nurses faced challenges at with a positive attitude, which helped them find meaning in their lives. In the limited life course, he left behind a great historical track of defending the health of the Chinese people. This study provides insight into the professional and personal lives of nurses in acute- and critical-care units during the pandemic in Taiwan, and the findings can help policymakers plan for future pandemics. © 2022 Chinese Public Health Association of Taiwan. All rights reserved.

13.
Education Sciences ; 12(9), 2022.
Article in English | Scopus | ID: covidwho-2055170

ABSTRACT

This study explores undergraduate engineering and education students’ perspectives on their interdisciplinary teams throughout the rapid transition to online learning and instruction from a face-to-face to a virtual format. In this qualitative study, students’ reflections and focus groups from three interdisciplinary collaborations were analyzed using the lens of Social Cognitive Theory. COVID-19 created a dramatic change in the environment such that the most immediate and direct impact on students’ experiences was on the environmental aspects of Bandura’s triadic reciprocal determinism model, which then triggered behavioral and personal responses to adapt to the new environment. Subsequent evidence of reciprocal effects between environmental, behavioral, and personal factors took place as students continued to adapt. Results suggest that the modifications made to transition the project fully online were meaningful experiences for students’ learning and teaching of engineering through teams. This interdisciplinary partnership provided both pre-service teachers and undergraduate engineering students with the opportunity to learn and practice content and professional skills that will be essential for success in future work environments. © 2022 by the authors.

14.
J Hosp Infect ; 129: 22-30, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-2049480

ABSTRACT

BACKGROUND: Hospital infection control measures against coronavirus disease 2019 (COVID-19) are often based on expert discretion due to the lack of detailed guidelines. AIM: To survey the current strategies for preventing the transmission of COVID-19 in medical institutions. METHODS: Thirteen key issues related to the prevention of COVID-19 transmission within medical institutions were selected via discussion among infectious diseases specialists, and related critical questions were obtained following a review of national-level guidelines in government databases. Six hospitals had an open survey between 11th and 25th August 2020 to provide responses to these topics. An online questionnaire developed from these data was sent to infection control teams at 46 hospitals in South Korea between 31st January 2021 and 20th February 2021. FINDINGS: All 46 hospitals responded to the survey. All operated screening clinics, but 89.1% (41/46) allowed symptomatic patients without COVID-19-associated symptoms to visit general outpatient clinics. Most hospitals (87.2%, 34/39) conducted polymerase chain reaction (PCR) tests for all hospitalized patients. Of 35/46 (76.1%) hospitals with pre-emptive isolation policies for hospitalized patients, 31 (88.6%) released patients from isolation after a single negative PCR test, while most (76.9%, 20/26) allowed shared-room accommodation for patients meeting the national criteria for release from isolation despite positive PCR results with above cycle threshold values (34.6%, 9/26), or after a certain period that satisfied the national criteria (26.9%, 7/26). CONCLUSION: Individual hospitals in South Korea are currently relying on experience to frame relevant guidelines, and responded differently to some infection control issues on hospital settings during the COVID-19 pandemic.


Subject(s)
COVID-19 , Humans , COVID-19/prevention & control , Pandemics/prevention & control , SARS-CoV-2 , Republic of Korea/epidemiology , Hospitals , Surveys and Questionnaires
15.
129th ASEE Annual Conference and Exposition: Excellence Through Diversity, ASEE 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2045824

ABSTRACT

This work-in-progress paper describes engineering students' experiences in an NSF-funded project that partnered undergraduate engineering students with pre-service teachers to plan and deliver robotics lessons to fifth graders at a local school. This project aims to address an apparent gap between what is taught in academia and industry's expectations of engineers to integrate perspectives from outside their field to solve modern societal problems requiring a multidisciplinary approach. Working in small teams over Zoom, participating engineering, education, and fifth grade students designed, built, and coded bio-inspired COVID companion robots. The goal for the engineering students was to build new interprofessional skills, while reinforcing technical skills. The collaborative activities included: (1) training with Hummingbird BitTM hardware (e.g. sensors, servo motors) and coding platform, (2) preparing robotics lessons for fifth graders that explained the engineering design process (EDP), and (3) guiding the fifth graders in the design of their robots. Additionally, each undergraduate engineering student designed a robot following the theme developed with their preservice teacher and fifth grade partners. The intervention took place in Spring 2021 amidst the COVID-19 pandemic, necessitating the investigators to make critical decisions to address challenges of implementing the intervention in an online setting. This paper describes those decisions as it investigates how the cross-disciplinary, mixed-aged collaboration with preservice teachers and fifth graders impacted undergraduate engineering students' learning and investment during the design process of their robots. Preliminary results of a regression analysis revealed a relationship between the engineering students' robot rankings and post-scores on the design process knowledge survey (r = 0.92). Consistencies and a few anomalies in this pattern were explained using qualitative reflections which were analyzed to determine students' level of investment in the project, overall perceptions, and the extent to which they focused on the fifth graders' ideas in their designs. In general, robot quality was linked to both undergraduate engineering students' level of investment and whether they focused on the fifth graders' ideas in their designs. Engineering students' overall perceptions of the project were generally positive, appreciating the role of cross-disciplinary and mixed-aged collaborations in their learning to brainstorm innovative solutions and interact effectively with professionals outside of engineering as they embark on tackling societal problems in the real world. © American Society for Engineering Education, 2022.

16.
J Med Internet Res ; 24(8): e30902, 2022 08 23.
Article in English | MEDLINE | ID: covidwho-2022319

ABSTRACT

BACKGROUND: Care coordination is challenging but crucial for children with medical complexity (CMC). Technology-based solutions are increasingly prevalent but little is known about how to successfully deploy them in the care of CMC. OBJECTIVE: The aim of this study was to assess the feasibility and acceptability of GoalKeeper (GK), an internet-based system for eliciting and monitoring family-centered goals for CMC, and to identify barriers and facilitators to implementation. METHODS: We used the Consolidated Framework for Implementation Research (CFIR) to explore the barriers and facilitators to the implementation of GK as part of a clinical trial of GK in ambulatory clinics at a children's hospital (NCT03620071). The study was conducted in 3 phases: preimplementation, implementation (trial), and postimplementation. For the trial, we recruited providers at participating clinics and English-speaking parents of CMC<12 years of age with home internet access. All participants used GK during an initial clinic visit and for 3 months after. We conducted preimplementation focus groups and postimplementation semistructured exit interviews using the CFIR interview guide. Participant exit surveys assessed GK feasibility and acceptability on a 5-point Likert scale. For each interview, 3 independent coders used content analysis and serial coding reviews based on the CFIR qualitative analytic plan and assigned quantitative ratings to each CFIR construct (-2 strong barrier to +2 strong facilitator). RESULTS: Preimplementation focus groups included 2 parents (1 male participant and 1 female participant) and 3 providers (1 in complex care, 1 in clinical informatics, and 1 in neurology). From focus groups, we developed 3 implementation strategies: education (parents: 5-minute demo; providers: 30-minute tutorial and 5-minute video on use in a clinic visit; both: instructional manual), tech support (in-person, virtual), and automated email reminders for parents. For implementation (April 1, 2019, to December 21, 2020), we enrolled 11 providers (7 female participants, 5 in complex care) and 35 parents (mean age 38.3, SD 7.8 years; n=28, 80% female; n=17, 49% Caucasian; n=16, 46% Hispanic; and n=30, 86% at least some college). One parent-provider pair did not use GK in the clinic visit, and few used GK after the visit. In 18 parent and 9 provider exit interviews, the key facilitators were shared goal setting, GK's internet accessibility and email reminders (parents), and GK's ability to set long-term goals and use at the end of visits (providers). A key barrier was GK's lack of integration into the electronic health record or patient portal. Most parents (13/19) and providers (6/9) would recommend GK to their peers. CONCLUSIONS: Family-centered technologies like GK are feasible and acceptable for the care of CMC, but sustained use depends on integration into electronic health records. TRIAL REGISTRATION: ClinicalTrials.gov NCT03620071; https://clinicaltrials.gov/ct2/show/NCT03620071.


Subject(s)
Patient Portals , Adult , Child , Feasibility Studies , Female , Humans , Male , Parents , Surveys and Questionnaires , Technology
17.
19th International Conference on Ubiquitous Robots, UR 2022 ; : 243-247, 2022.
Article in English | Scopus | ID: covidwho-2019017

ABSTRACT

With the COVID-19 outbreak, people with disabilities have faced difficulties in managing their health owing to restrictions on medical access and use. Therefore, this study aimed to develop an Internet of Things-based health information-sharing mobile app for the disabled and their caregivers and evaluate its usability in maintaining access to health care services. As a first step, 19 user needs were evaluated through the Daily Health app 1.0, developed for the disabled by the National Rehabilitation Center. Based on these needs, the study participants proceeded with mind maps and personas to derive the User Interface. Subsequently, the Daily Health 2.0 program was designed, and heuristic and usability evaluations were conducted by experts. The Daily Health app 2.0 beta version was developed by modifying the detailed functions and design of the app based on the results of experts' opinions. Finally, a usability evaluation was conducted for app users. The app developed in this study will contribute to the efficient health management of people with disabilities in non-face-to-face situations. When combined with robot technology, it is expected that more effective health management will be possible by replacing physical functions that are difficult for people with disabilities. © 2022 IEEE.

18.
Blood Cancer Discov ; 3(6): 481-489, 2022 11 02.
Article in English | MEDLINE | ID: covidwho-2020565

ABSTRACT

The anti-spike T-cell and antibody responses to SARS-CoV-2 mRNA vaccines in patients with B-cell malignancies were examined in a real-world setting. A next-generation sequencing (NGS)-based molecular assay was used to assess SARS-CoV-2-specific T-cell responses. After the second dose, 58% (166/284) of seropositive and 45% (99/221) of seronegative patients display anti-spike T cells. The percentage of patients who displayed T-cell response was higher among patients receiving mRNA-1273 vaccines compared with those receiving BNT162b2 vaccines. After the third vaccination, 40% (137/342) of patients seroconverted, although only 22% displayed sufficient antibody levels associated with the production of neutralizing antibodies. 97% (717/738) of patients who were seropositive before the third dose had markedly elevated anti-spike antibody levels. Anti-spike antibody levels, but not T-cell responses, were depressed by B cell-directed therapies. Vaccinated patients with B-cell malignancies with a poor response to SARS-CoV-2 vaccines may remain vulnerable to COVID-19 infections. SIGNIFICANCE: This study represents the first investigation of SARS-CoV-2-specific immune responses to vaccination in a patient registry using an NGS-based method for T-cell receptor repertoire-based analysis combined with anti-spike antibody assessments. Vaccinated patients with B cell-derived hematologic malignancies are likely at higher risk of infection or severe COVID-19. This article is highlighted in the In This Issue feature, p. 476.


Subject(s)
COVID-19 , Hematologic Neoplasms , Humans , Antibody Formation , COVID-19 Vaccines , SARS-CoV-2 , Spike Glycoprotein, Coronavirus , T-Lymphocytes , Antibodies, Viral , BNT162 Vaccine
20.
Journal of Clinical Oncology ; 40(16), 2022.
Article in English | EMBASE | ID: covidwho-2009589

ABSTRACT

Background: Complicating the pandemic are the healthcare disparities experienced by ethnic minorities, including Black and Hispanic Americans. This is further exacerbated in those ethnic subgroups, especially if they have comorbidities, including cancer. With the introduction of COVID-19 vaccines, the shift is now focused on promoting vaccination. However, vaccine hesitancy and motives of why ethnic minority cancer patients receive or do not receive vaccines have not been explored and are the focus of this study. Methods: A cross-sectional survey was administered among cancer patients to understand the knowledge and attitude towards COVID-19 vaccines at a single institution in a predominantly ethnic minority population between February 1-June 30, 2021. The participant's inclusion criteria were >18 years old and diagnosed with solid or hematologic malignancy. Descriptive statistics were used to summarize the patient characteristics, COVID-19 vaccine knowledge, and uptake motives. A composite score of COVID-19 and vaccine knowledge was derived and its role on vaccination status was assessed using a multivariable logistic regression model. Results: Of 52 patients surveyed, COVID-19 vaccination prevalence during the survey was 40.4% (95% CI: 27, 54.9). Participants' average (sd) age was 63.5 (13.6) years;42% were male, 36% were Black, and 30% Hispanic;65% were receiving active treatment for their cancer. Seventy-nine percent believed COVID-19 infection to be dangerous or harmful to them, 61% were concerned about the side effects of the COVID-19 vaccine, yet 65% considered vaccines safe. Those refusing the vaccine (n=7) cited side effects (71%) or believed that the vaccine was not needed (57%). Of those who were unvaccinated (n=31), 48.4% (n=15) got vaccinated post-survey. The odds of vaccination was 3.79 (1.63, 8.82) times higher with a 1 unit increase in COVID-19 knowledge score but was not significant in the multivariable model. The final model suggested that the odds of vaccination increased 2.9 times more for a 1 unit increase in vaccine knowledge score;Blacks were two times more likely to get vaccinated and those with more than high school education had a five-fold increase in vaccination. The model results are presented in Table. Conclusions: This exploratory study has demonstrated that there are multiple reasons why an ethnic minority cancer patient would be vaccinated and possible reasons why they would not. This information will become important in improving vaccine campaigns targeting these populations and ensuring their safety and protection against COVID-19.

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