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Lrec 2022: Thirteen International Conference on Language Resources and Evaluation ; : 3407-3416, 2022.
Article in English | Web of Science | ID: covidwho-2307697
Journal of Public Health in Africa ; 13(s2) (no pagination), 2022.
Article in English | EMBASE | ID: covidwho-2163855
35th International Florida Artificial Intelligence Research Society Conference, FLAIRS-35 2022 ; 35, 2022.
Article in English | Scopus | ID: covidwho-1879808
Chinese Journal of Pharmaceutical Biotechnology ; 28(4):395-399, 2021.
Article in Chinese | Scopus | ID: covidwho-1566895
2020 Ieee International Conference on Bioinformatics and Biomedicine ; : 1063-1067, 2020.
Article in English | Web of Science | ID: covidwho-1354403
International Journal of Chinese & Comparative Philosophy of Medicine ; 18(2):109-113, 2020.
Article in Chinese | Web of Science | ID: covidwho-1022890
New Microbes New Infect ; 39: 100814, 2021 Jan.
Article in English | MEDLINE | ID: covidwho-988948


Coronavirus disease 2019 (COVID-19) is still a global epidemic. Several studies of individuals with severe COVID-19 regard convalescent plasma (CP) transfusion as an effective therapy. However, no significant improvements are found in randomized clinical trials of CP treatment. Until now, data for individuals with mild COVID-19 transfused CP were lacking. This study recruited eight individuals with mild COVID-19 who received at least one dose of CP transfusion. After CP therapy, the clinical symptoms of all individuals improved. Lymphocyte counts tended to increase, and lactate dehydrogenase, creatine kinase and aspartate aminotransferase tended to decrease. However, C-reactive protein increased transiently in three individuals. The median time for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid test to become negative was 2.5 days after CP transfusion. The study shows the potential benefits of CP. Meanwhile, CP probably enhances the inflammatory response to SARS-CoV-2 temporarily in people with insufficient antiviral immunity. However, the effects of CP are not permanent.

Epidemiol Infect ; 148: e141, 2020 07 06.
Article in English | MEDLINE | ID: covidwho-633492


The pandemic of coronavirus disease 2019 (COVID-19) has posed serious challenges. It is vitally important to further clarify the epidemiological characteristics of the COVID-19 outbreak for future study and prevention and control measures. Epidemiological characteristics and spatial-temporal analysis were performed based on COVID-19 cases from 21 January 2020 to 1 March 2020 in Shandong Province, and close contacts were traced to construct transmission chains. A total of 758 laboratory-confirmed cases were reported in Shandong. The sex ratio was 1.27: 1 (M: F) and the median age was 42 (interquartile range: 32-55). The high-risk clusters were identified in the central, eastern and southern regions of Shandong from 25 January 2020 to 10 February 2020. We rebuilt 54 transmission chains involving 209 cases, of which 52.2% were family clusters, and three widespread infection chains were elaborated, occurring in Jining, Zaozhuang and Liaocheng, respectively. The geographical and temporal disparity may alert public health agencies to implement specific measures in regions with different risk, and should attach importance on how to avoid household and community transmission.

Coronavirus Infections/epidemiology , Coronavirus Infections/transmission , Pneumonia, Viral/epidemiology , Pneumonia, Viral/transmission , Adult , COVID-19 , China/epidemiology , Contact Tracing , Female , Geographic Information Systems , Humans , Male , Middle Aged , Pandemics , Time Factors