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1.
Medicinal Plant ; 13(1):84-94, 2022.
Article in English | CAB Abstracts | ID: covidwho-2026016

ABSTRACT

Post-traumatic stress disorder(PTSD) is a kind of mental disorder caused by severe traumatic events. It has a high incidence, a serious of impacts on the physical and mental health of patients. Especially in the current situation of COVID-19, the researches on PTSD are particularly important, but the choice of drugs available for PTSD is limited and it is often accompanied by adverse reactions. In the field of acupuncture, there are many clinical research evidences suggested that PTSD is a predominant disease of acupuncture. However, its action mechanisms have not been fully elucidated, so the possible mechanisms of acupuncture in treating PTSD were discussed.

2.
J Clean Prod ; 368: 132994, 2022 Sep 25.
Article in English | MEDLINE | ID: covidwho-2015585

ABSTRACT

The Corona Virus Disease 2019 (COVID-19) has led to a decline in carbon emissions or an improvement in air quality. Yet little is known about how the pandemic has affected the "low-carbon" energy transition. Here, using difference-in-differences (DID) models with historical controls, this study analyzed the overall impact of COVID-19 on China's low-carbon power generation and examined the COVID-19 effect on the direction of the energy transition with a monthly province-specific, source-specific dataset. It was found that the COVID-19 pandemic increased the low-carbon power generation by 4.59% (0.0648 billion kWh), mainly driven by solar and wind power generation, especially solar power generation. Heterogeneous effects indicate that the pandemic has accelerated the transition of the power generation mix and the primary energy mix from carbon-intensive energy to modern renewables (such as solar and wind power). Finally, this study put forward several policy implications, including the need to promote the long-term development of renewables, green recovery, and so on.

3.
Diagnostics (Basel) ; 12(7)2022 Jun 21.
Article in English | MEDLINE | ID: covidwho-1963772

ABSTRACT

The associations of prognostic nutritional index (PNI) with disease severity and mortality in patients with coronavirus disease 2019 (COVID-19) remain unclear. Electronic databases, including MEDLINE, EMBASE, Google scholar, and Cochrane Library, were searched from inception to 10 May 2022. The associations of PNI with risk of mortality (primary outcome) and disease severity (secondary outcome) were investigated. Merged results from meta-analysis of 13 retrospective studies (4204 patients) published between 2020 and 2022 revealed a lower PNI among patients in the mortality group [mean difference (MD): -8.65, p < 0.001] or severity group (MD: -5.19, p < 0.001) compared to those in the non-mortality or non-severity groups. A per-point increase in PNI was associated with a reduced risk of mortality [odds ratio (OR) = 0.84, 95% CI: 0.79 to 0.9, p < 0.001, I2 = 67.3%, seven studies] and disease severity (OR = 0.84, 95% CI: 0.77 to 0.92, p < 0.001, I2 = 83%, five studies). The pooled diagnostic analysis of mortality yielded a sensitivity of 0.76, specificity of 0.71, and area under curve (AUC) of 0.79. Regarding the prediction of disease severity, the sensitivity, specificity, and AUC were 0.8, 0.61, and 0.65, respectively. In conclusion, this study demonstrated a negative association between PNI and prognosis of COVID-19. Further large-scale trials are warranted to support our findings.

4.
Int J Environ Res Public Health ; 19(13)2022 Jun 22.
Article in English | MEDLINE | ID: covidwho-1934030

ABSTRACT

Based on compensatory control theory, the aim of this study was to examine the effects of perceived control on people's acceptance of genetically modified (GM) foods by using both correlational and experimental methods. Compensatory control theory proposes that the lower an individual's perceived control, the higher their need for structure, order, and certainty. Therefore, based on beliefs about GM foods that make some people less certain that those foods are as safe as traditional foods, we hypothesized that individuals with lower levels of perceived control are more inclined to reject GM foods. The analysis of questionnaire responses in Study 1 revealed that individuals' sense of control negatively predicted their risk perception of GM foods, while the need for structure played a mediating role. In Study 2, using a between-subject design, we manipulated participants' perceived control (higher vs. lower) and subsequently measured their risk perception and purchasing preferences for GM foods. The results in Study 2 show that under lower control conditions, individuals recognize higher risks related to GM foods, which, in turn, decreases their willingness to purchase GM foods. These results not only suggest that perceived control is a potential influential personal factor of the acceptance of GM foods but also extend the scope of the application of compensatory control theory.


Subject(s)
Food, Genetically Modified , Consumer Behavior , Food , Humans , Intention , Plants, Genetically Modified
5.
Diagnostics (Basel) ; 12(7)2022 Jul 10.
Article in English | MEDLINE | ID: covidwho-1928517

ABSTRACT

Although the fibrinogen-to-albumin ratio (F/R ratio) has been used as an inflammation marker to predict clinical outcomes in patients with cardiovascular diseases, its association with the prognosis of patients with coronavirus disease 2019 (COVID-19) remains unclear. Electronic databases including EMBASE, MEDLINE, Google Scholar, and Cochrane Library were searched from inception to 20 June 2022. The associations of F/R ratio with poor prognosis (defined as the occurrence of mortality or severe disease) were investigated in patients with COVID-19. A total of 10 studies (seven from Turkey, two from China, one from Croatia) involving 3675 patients published between 2020 and 2022 were eligible for quantitative syntheses. Merged results revealed a higher F/R ratio in the poor prognosis group (standardized mean difference: 0.529, p < 0.001, I2 = 84.8%, eight studies) than that in the good prognosis group. In addition, a high F/R ratio was associated with an increased risk of poor prognosis (odds ratio: 2.684, I2 = 59.5%, five studies). Pooled analysis showed a sensitivity of 0.75, specificity of 0.66, and area under curve of 0.77 for poor prognosis prediction. In conclusion, this meta-analysis revealed a positive correlation between F/A ratio and poor prognostic outcomes of COVID-19. Because of the limited number of studies included, further investigations are warranted to support our findings.

6.
Remote Sens Appl ; 27: 100806, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-1914973

ABSTRACT

The COVID-19 pandemic has profoundly affected human society on a global scale. COVID-19 pandemic control measures have led to significant changes in nighttime light (NTL) and air quality. Four cities that were severely impacted by the pandemic and that implemented different pandemic control measures, namely, Wuhan (China), Delhi (India), New York (United States), and Rome (Italy), were selected as study areas. The Visible Infrared Imaging Radiometer Suite (VIIRS) and air quality data were used to study the variation characteristics of NTL and air quality in the four cities in 2020. NTL brightness in Wuhan, Delhi, New York, and Rome decreased by 8.88%, 17.18%, 8.21%, and 6.33%, respectively, compared with pre-pandemic levels; in the resumption phase Wuhan and Rome NTL brightness recovered by 13.74% and 3.38%, but Delhi and New York decreased by 16.23% and 4.99%. Nitrogen dioxide (NO2) concentrations in the lockdown periods of Wuhan, Delhi, New York, and Rome decreased by 65.07%, 68.75%, 55.59%, and 56.81%, respectively; PM2.5 decreased by 49.25%, 69.40%, 52.54%, and 66.67%. Air quality improved, but ozone (O3) concentrations increased significantly during the lockdown periods. The methods presented herein can be used to investigate the impact of pandemic control measures on urban lights and air quality.

7.
J Pharm Biomed Anal ; 215: 114793, 2022 Jun 05.
Article in English | MEDLINE | ID: covidwho-1895251

ABSTRACT

Glycyrrhiza uralensis is a popular medicinal plant worldwide. Its roots and rhizomes are used as the traditional Chinese medicine Gan-Cao. However, little is known on medicinal potential and chemistry of the other parts of the plant. In this work, the biological activities and chemical components of the roots, stems, leaves, and seeds of G. uralensis were investigated comparatively. The four parts exhibited different but noticeable biological activities. The chemicals in the four parts were globally characterized by liquid chromatography coupled with mass spectrometry (LC/MS) on a Thermo Vanquish UHPLC system connected to a Q-Exactive quadrupole Orbitrap mass spectrometer. By integrating molecular networking, compound spectral matching, MS2LDA-based substructure recognition, and reference standards comparison, a total of 1301 compounds were rapidly characterized. Three flavonoid C-glycosides were purified and their structures were identified by NMR spectroscopic analysis. Orthogonal partial least squares-discriminate analysis (OPLS-DA) further revealed 196 differential chemicals for the four parts. This work will promote the medicinal resource utilization of G. uralensis.


Subject(s)
Glycyrrhiza uralensis , Glycyrrhiza , Plants, Medicinal , Chromatography, High Pressure Liquid , Glycyrrhiza uralensis/chemistry , Medicine, Chinese Traditional , Plant Roots/chemistry , Rhizome/chemistry
8.
Diagnostics ; 12(7):1515, 2022.
Article in English | MDPI | ID: covidwho-1894012

ABSTRACT

The associations of prognostic nutritional index (PNI) with disease severity and mortality in patients with coronavirus disease 2019 (COVID-19) remain unclear. Electronic databases, including MEDLINE, EMBASE, Google scholar, and Cochrane Library, were searched from inception to 10 May 2022. The associations of PNI with risk of mortality (primary outcome) and disease severity (secondary outcome) were investigated. Merged results from meta-analysis of 13 retrospective studies (4204 patients) published between 2020 and 2022 revealed a lower PNI among patients in the mortality group [mean difference (MD): −8.65, p < 0.001] or severity group (MD: −5.19, p < 0.001) compared to those in the non-mortality or non-severity groups. A per-point increase in PNI was associated with a reduced risk of mortality [odds ratio (OR) = 0.84, 95% CI: 0.79 to 0.9, p < 0.001, I2 = 67.3%, seven studies] and disease severity (OR = 0.84, 95% CI: 0.77 to 0.92, p < 0.001, I2 = 83%, five studies). The pooled diagnostic analysis of mortality yielded a sensitivity of 0.76, specificity of 0.71, and area under curve (AUC) of 0.79. Regarding the prediction of disease severity, the sensitivity, specificity, and AUC were 0.8, 0.61, and 0.65, respectively. In conclusion, this study demonstrated a negative association between PNI and prognosis of COVID-19. Further large-scale trials are warranted to support our findings.

9.
BMC Nephrol ; 23(1): 175, 2022 05 06.
Article in English | MEDLINE | ID: covidwho-1892181

ABSTRACT

BACKGROUND: Coronavirus disease 2019 (COVID-19) is identified as the pneumonia and acute respiratory distress syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). The intravascular thrombotic phenomena related to the COVID-19 are emerging as an important complication that contribute to significant mortality. CASE PRESENTATION: We present a 62-year-old man with severe COVID-19 and type 2 diabetes. After symptomatic and supportive treatment, the respiratory function was gradually improved. However, the patient suddenly developed abdominal pain, and the enhanced CT scan revealed renal artery thrombosis. Given the risk of surgery and the duration of the disease, clopidogrel and heparin sodium were included in the subsequent treatment. The patient recovered and remained stable upon follow-up. CONCLUSIONS: Thrombosis is at a high risk in patients with severe COVID-19 pneumonia because of hypercoagulable state, blood stasis and endothelial injury. Thrombotic events caused by hypercoagulation status secondary to vascular endothelial injury deserves our attention. Because timely anticoagulation can reduce the risk of early complications, as illustrated in this case report.


Subject(s)
COVID-19 , Diabetes Mellitus, Type 2 , Thrombophilia , Thrombosis , COVID-19/complications , Diabetes Mellitus, Type 2/complications , Humans , Male , Middle Aged , RNA, Viral , Renal Artery/diagnostic imaging , SARS-CoV-2 , Thrombosis/diagnostic imaging , Thrombosis/etiology
10.
Int J Environ Res Public Health ; 19(12)2022 06 08.
Article in English | MEDLINE | ID: covidwho-1884176

ABSTRACT

(1) Aims: This study explored the mechanism by which exposure to different information sources on social media influences Chinese parents' intention to vaccinate their children against COVID-19. (2) Methods: We developed a research framework based on the Stimulus-Organism-Response (SOR) theory to illustrate how exposure to information sources on social media increases vaccine confidence and, as a result, parents' intentions regarding pediatric vaccination. The partial least square structural equation modeling (PLS-SEM) method was used to test the data collected through an online survey (687 valid samples). (3) Results: The government approval of vaccines fuels vaccination confidence and acts as a mediator between (a) mass media, government new media, and key opinion leaders, and (b) perceived effectiveness and side effects (safety) of vaccines. (4) Conclusions: The mass media, government new media, and key opinion leaders are crucial sources for encouraging parents to vaccinate their children since they boost the vaccination trust. The focus of COVID-19 vaccination promotion should be to strengthen parents' trust in the government, combined with publicizing the effectiveness and side effects (safety) of vaccines.


Subject(s)
COVID-19 Vaccines , COVID-19 , Health Knowledge, Attitudes, Practice , Parents , Vaccination , COVID-19/prevention & control , Child , China , Humans , Information Dissemination , Intention , Parents/psychology , Social Media , Trust , Vaccination/psychology
11.
Int J Environ Res Public Health ; 19(10)2022 05 18.
Article in English | MEDLINE | ID: covidwho-1862792

ABSTRACT

This study aims to explore the effects of personality traits on online rumor sharing during the novel coronavirus (COVID-19) pandemic and the mediating role of the fear of COVID-19 between them. We conducted this research using a web-based questionnaire distributed to 452 university students who were invited to fill it out. The partial least square structural equation modeling (PLS-SEM) method was used to test the data and model, with the yielded results demonstrating that three-extroversion, emotional instability, and conscientiousness-of the Big Five personality traits are positively related to a fear of COVID-19, with this fear positively affecting online rumor sharing. Moreover, fear of COVID-19 was found to act as a mediator between personality traits and online rumor sharing; thus, we can conclude that persons with high levels of extroversion, emotional instability, and conscientiousness are more likely to share rumors online due to a fear of COVID-19. This study furthers our understanding of the psychological mechanism by which personality traits influence online rumor sharing and provides references for anti-rumor campaigns taking place during the COVID-19 pandemic, as it identifies key groups and sheds light on the necessity of reducing people's fear of COVID-19.


Subject(s)
COVID-19 , COVID-19/epidemiology , Fear , Humans , Pandemics , Personality , Surveys and Questionnaires
12.
Biosens Bioelectron ; 207: 114169, 2022 Jul 01.
Article in English | MEDLINE | ID: covidwho-1748198

ABSTRACT

Isothermal amplification methods are a promising trend in virus detection because of their superiority in rapidity and sensitivity. However, the generation of false positives and limited multiplexity are major bottlenecks that must be addressed. In this study, we developed a multiplex Argonaute (Ago)-based nucleic acid detection system (MULAN) that integrates rapid isothermal amplification with the multiplex inclusiveness of a single Ago for simultaneous detection of multiple targets such as SARS-CoV-2 and influenza viruses. Owing to its high specificity, MULAN can distinguish targets at a single-base resolution for mutant genotyping. Moreover, MULAN also supports portable and visible devices with a limit of detection of five copies per reaction. Validated by SARS-CoV-2 pseudoviruses and clinical samples of influenza viruses, MULAN showed 100% agreement with quantitative reverse-transcription PCR. These results demonstrated that MULAN has great potential to facilitate reliable, easy, and quick point-of-care diagnosis for promoting the control of infectious diseases.


Subject(s)
Biosensing Techniques , COVID-19 , Orthomyxoviridae , COVID-19/diagnosis , Humans , Molecular Diagnostic Techniques/methods , Nucleic Acid Amplification Techniques/methods , Orthomyxoviridae/genetics , RNA, Viral/analysis , RNA, Viral/genetics , SARS-CoV-2/genetics , Sensitivity and Specificity
13.
Healthcare (Basel) ; 10(3)2022 Feb 22.
Article in English | MEDLINE | ID: covidwho-1702142

ABSTRACT

Football is a sport involving dynamic movements, and ankle sprains are common sports injuries experienced by football players. Ankle sprains exhibit a high recurrence rate, and rehabilitation training is effective; however, expert-supervised rehabilitation (SVR) at training centers is difficult due to the recent COVID-19 pandemic. This study investigated the effects of mobile-based rehabilitation (MBR) performed at home by high school football players. Sixty players (SVR: 30 and MBR: 30) with recurrent ankle sprains were analyzed. The rehabilitation program consisted of strength and balance training, and the training intensity was gradually increased from week 1 to week 8. The SVR group underwent training at the center with experts, and the BMR group were provided with programs and feedback using mobile devices. Ankle muscle strength was evaluated by measuring isometric eversion, inversion, plantarflexion, and dorsiflexion contraction using a hand-held dynamometer, and dynamic balance was assessed using the Y-balance test (YBT; anterior, posteromedial, and posterolateral); the Foot and Ankle Outcome Score (FAOS) was used for the subjective evaluation. Measurements were conducted at weeks 1, 4, and 8. The patients visited the clinic within 1 week after the injury, and the first test was conducted after consent to participate in the research. Patients underwent the second test at an average of 3.2 weeks after the first test, and the last test at an average of 4.4 weeks after the second test. Although only the SVR group exhibited improvement in strength (eversion and dorsiflexion), YBT and subjective satisfaction at week 4, these measurements improved in both the SVR and MBR groups at week 8. Therefore, mobile-based rehabilitation could be a suitable alternative for high school athletes with ankle sprains who cannot undergo supervised rehabilitation.

14.
EuropePMC; 2020.
Preprint in English | EuropePMC | ID: ppcovidwho-312700

ABSTRACT

Background: Coronavirus disease 2019 (COVID-19) is identified as the pneumonia and acute respiratory distress syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). The intravascular thrombotic phenomena related to the COVID-19 are emerging as an important complication that contribute to significant mortality. Case presentationWe present a 62-year-old man with severe COVID-19 and type 2 diabetes. After symptomatic and supportive treatment, the respiratory function was gradually improved. However, the patient suddenly developed abdominal pain, and the enhanced CT scan revealed acute left renal artery embolism. Given the risk of surgery and the duration of the disease, clopidogrel and heparin sodium were included in the subsequent treatment. Later, the abdominal pain and hypercoagulable state disappeared, and the effect was still satisfactory.ConclusionsThis report clarifies the challenges posed by embolism complications in the management of COVID-19 patients. Thrombosis is at a high risk in patients with severe COVID-19 pneumonia because of hypercoagulable state, blood stasis and endothelial injury. Thrombotic events caused by hypercoagulation status secondary to vascular endothelial injury deserves our attention. Because timely anticoagulation can reduce the risk of early complications, as illustrated in this case report.

15.
EuropePMC; 2020.
Preprint in English | EuropePMC | ID: ppcovidwho-315242

ABSTRACT

After fitting a topic model to 40,927 COVID-19-related paragraphs in 3,581 earnings calls over the period January 22 to April 30, 2020, we obtain firm-level measures of exposure and response related to COVID-19 for 2,894 U.S. firms. We show that despite the large negative impact of COVID-19 on their operations, firms with a strong corporate culture outperform their peers without a strong culture. Moreover, these firms are more likely to support their community, embrace digital transformation, and develop new products than those peers. We conclude that corporate culture is an intangible asset designed to meet unforeseen contingencies as they arise.

16.
Decis Support Syst ; : 113752, 2022 Feb 12.
Article in English | MEDLINE | ID: covidwho-1676707

ABSTRACT

This paper investigates how information timeliness and richness affect public engagement using text data from China's largest social media platform during times of the COVID-19 pandemic. We utilize a similarity calculation method based on natural language processing (NLP) and text mining to evaluate three dimensions of information timeliness: retrospectiveness, immediateness, and prospectiveness. Public engagement is divided into breadth and depth. The empirical results show that information retrospectiveness is negatively associated with public engagement breadth but positively with depth. Both information immediateness and prospectiveness improved the breadth and depth of public engagement. Interestingly, information richness has a positive moderating effect on the relationships between information retrospectiveness, prospectiveness, and public engagement breadth but no significant effects on immediateness; meanwhile, it has a negative moderating effect on the relationship between retrospectiveness and depth but a positive effect on immediateness, prospectiveness. In the extension analysis, we constructed a supervised NLP model to identify and classify health emergency-related information (epidemic prevention and help-seeking) automatically. We find that public engagement differs in the two emergency-related information categories. The findings can promote a more responsive public health strategy that magnifies the transfer speed for critical information and mitigates the negative impacts of information uncertainty or false information.

17.
Journal of Financial and Quantitative Analysis ; 56(7):2545, 2021.
Article in English | ProQuest Central | ID: covidwho-1527938

ABSTRACT

After fitting a topic model to 40,927 COVID-19–related paragraphs in 3,581 earnings calls over the period Jan. 22–Apr. 30, 2020, we obtain firm-level measures of exposure and response related to COVID-19 for 2,894 U.S. firms. We show that despite the large negative impact of COVID-19 on their operations, firms with a strong corporate culture outperform their peers without a strong culture. Moreover, these firms are more likely to support their community, embrace digital transformation, and develop new products than those peers. We conclude that corporate culture is an intangible asset designed to meet unforeseen contingencies as they arise.

18.
Journal of Accounting and Public Policy ; : 106920-106920, 2021.
Article in English | PMC | ID: covidwho-1509911
19.
Int J Gen Med ; 14: 6787-6793, 2021.
Article in English | MEDLINE | ID: covidwho-1470713

ABSTRACT

OBJECTIVE: To investigate the effect of comprehensive treatment on ocular surface function and the visual quality of online teachers with a mild-to-moderate dry eye condition during the early phase of coronavirus disease 2019 (COVID-19). METHODS: Secondary school online teachers diagnosed with a mild-to-moderate dry eye disease in our outpatient clinic from February to May 2020 were enrolled in this retrospective cross-section study, and all patients received dry eye comprehensive treatment. A questionnaire survey on eye-use habits, visual quality and dry eye-related indicators was collected before and after treatment (2 and 4 weeks). The changes and the correlations between indicators before and after treatment were compared. RESULTS: A total of 30 patients (15 females and 15 males) were included. After comprehensive treatment, patients had significantly higher central tear meniscus height (TMH), non-invasive first tear film breakup time (NIBUTf) and non-invasive average tear film breakup time (NIBUTav) than those before with statistical significance (P < 0.05). Lower ocular surface disease index (OSDI) and Meibomian gland scores were observed after treatment with statistical significance (P < 0.05). Objective scatter index (OSI), modulation transfer function (MTF) cutoff, strehl ratio (SR), and tear film objective scatter index (TF-OSI) were significantly improved after treatment (P < 0.05). Besides, TF-OSI was positively correlated with the changes in OSDI, Meibomian gland score, eye-use duration and OSI with statistical significance (P < 0.05), while it was negatively correlated with NIBUTf, NIBUTav, the TMH of the central lower eyelid, SR, sleep duration, conjunctival congestion and the MTF cutoff (P < 0.05), respectively. No correlation between TF-OSI and ciliary congestion was found (P > 0.05). CONCLUSION: Comprehensive treatment could effectively improve the symptoms and visual quality of online teachers with a mild-to-moderate dry eye condition during the early stage of COVID-19 pandemic.

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