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1.
Chinese Journal of Microbiology and Immunology (China) ; 42(3):171-177, 2022.
Article in Chinese | EMBASE | ID: covidwho-1928712

ABSTRACT

SARS-CoV-2, the pathogen of the COVID-19 pandemic, causes serious damage to human health and social stability.In severe COVID-19 cases, the infection triggers cytokine storm, resulting in multi-organ excessive inflammatory responses and even failure, which eventually leads to death.Recent studies have shown the activation of nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome plays an essential role in the pathogenesis of COVID-19.SARS-CoV-2 can activate NLRP3 inflammasome through several pathways, thereby inducing the release of a large number of pro-inflammatory cytokines.This article reviews the activation of NLRP3 inflammasome caused by SARS-CoV-2 infection and the possible molecular mechanisms, and summarizes the progress in targeted inhibition of NLRP3 inflammation aiming to provide a new strategy for the treatment of SARS-CoV-2 infection.

2.
Zhonghua Jie He He Hu Xi Za Zhi ; 45(7): 706-711, 2022 Jul 12.
Article in Chinese | MEDLINE | ID: covidwho-1911763

ABSTRACT

Coronavirus Disease-2019 (COVID-19) has been a major public health issue all over the world, placing a significant burden on available healthcare resources. The most common types of COVID-19 are the mild and common forms. Although the proportion of the severe-critical types is smaller, the rate of death is significantly higher and the medical resources required tend to be greater. Thus, a variety of scores based on other disease and COVID-19 were used to assess the risk of poor prognosis on the COVID-19, including the common scores for community-acquired pneumonia, sepsis and viral pneumonia. Unfortunately, the above scores often lacked an adequate description of the applicable population or were at high risk of bias with unknown applicability. Therefore, the article summarized the existing scores, aiming to provide a reference for clinical prognostic risk assessment.


Subject(s)
COVID-19 , Pneumonia, Viral , Humans , Pneumonia, Viral/diagnosis , Pneumonia, Viral/epidemiology , Prognosis , Risk Assessment , SARS-CoV-2
3.
2021 International Conference on Computing in Civil Engineering, I3CE 2021 ; : 1000-1007, 2021.
Article in English | Scopus | ID: covidwho-1908372

ABSTRACT

The pandemic of COVID-19 has caused severe disruptions in urban lives. Understanding and quantifying these disruptions is important to inform the development of targeted and effective measures to control the pandemic and its impact. One way of achieving this object is to measure the urban mobility perturbation caused by the pandemic. In this study, we built mobility-based networks for seven major metropolitan statistical areas (MSAs) across the United States in the years of 2019 and 2020, respectively. We quantified the disruptions of urban mobility by computing and comparing a set of network-based metrics before and during the pandemic. The proposed approach is able to uncover the impact of COVID-19 in cities and provides new insights into the resilience of cities when facing large-scale disasters. © 2021 Computing in Civil Engineering 2021 - Selected Papers from the ASCE International Conference on Computing in Civil Engineering 2021. All rights reserved.

4.
Integrated Optics: Devices, Materials, and Technologies XXVI 2022 ; 12004, 2022.
Article in English | Scopus | ID: covidwho-1891706

ABSTRACT

Interferometric scattering microscopy is a newly emerging alternative to fluorescence microscopy in biomedical research and diagnostic testing due to its ability to detect nano-objects such as individual proteins, extracellular vesicles, and virions individually through their intrinsic elastic light scattering. To improve the signal-to-noise ratio, we developed photonic resonator interferometric scattering microscopy (PRISM) in which a photonic crystal (PC) resonator is used as the sample substrate. The scattered light is amplified by the PC through resonant near-field enhancement, which then interferes with the <1% transmitted light to create intensity contrast. Importantly, the scattered photons assume the wavevectors defined by PC's photonic band structure, resulting in the ability to utilize a non-immersion objective without significant loss at illumination density as low as 25 W/cm2. We demonstrate virus and protein detection, including highly selective capture and counting of intact pseudotype SARS-CoV-2 from saliva with sensitivity equivalent to conventional nucleic acid tests. The results showcase the promise of nanophotonic surfaces in the development of resonance-enhanced interferometric microscopies, and as a single step, room temperature, and rapid viral detection technology. © 2022 SPIE.

5.
Psychosomatic Medicine ; 84(5):A40-A40, 2022.
Article in English | Web of Science | ID: covidwho-1885175
6.
Science of Advanced Materials ; 14(2):408-413, 2022.
Article in English | English Web of Science | ID: covidwho-1883369

ABSTRACT

The management of breast cancer patients in the current COVID-19 outbreak is challenging. Myelosuppres-sion associated with cancer treatment may increase the risk of infection in both hospitals and at home. We implemented the following strategy to reduce myelosuppression of adjuvant chemotherapy during the COVID-19 pandemic: (1) changing the original regimen of AC x 4-* wT x 12 to wT x 12-* AC x 4. (2) substitution of standard paclitaxel with nanoparticle albumin-bound (nab)-paclitaxel (nab-paclitaxel). For 43 patients who com-IP: 14.98.160.66 On: Fri, 13 May 2022 09:27:55 pleted nab-paclitaxel treatment, the compliance rate was 100%, without interruption or delay of nab-paclitaxel Copyright: American Scientific Publishers Delivered by Ingenta treatment. Dose reduction was necessary in 2 patients (4.6%) due to peripheral neuropathy. Thus, 98.6% of the planned doses were administered. As expected, the adjusted adjuvant regimen was safe and well toler-ated. Therefore wT x 12-* AC x 4 treatment procedure may be considered for breast cancer patients during COVID-19 pandemic.

7.
Journal of Bio-X Research ; 5(1):27-34, 2022.
Article in English | EMBASE | ID: covidwho-1816311

ABSTRACT

Objective: The coronavirus disease 2019 (COVID-19) epidemic resulting from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has still spread globally. The occurrence of the Delta variant, which is more infectious and spreads faster than earlier forms of the virus that causes COVID-19, makes infection prevention more challenging. Therefore, this study aimed to gain a comprehensive insight into the transmission routes of SARS-CoV-2 for curbing the propagation of SARS-CoV-2 in human populations. Methods: We studied a prospective cohort of 576 patients admitted consecutively to the First Affiliated Hospital of Guangzhou Medical University from January 21 to June 8, 2020. These patients were chosen based on their similar clinical phenotypes or imaging findings. There were 21 (3.6%) laboratory-confirmed COVID-19 patients (16 severe and 5 mild cases) and 555 non-COVID-19 patients. The antibody response and routes and duration of viral shedding were systematically evaluated in serial clinical specimens. Moreover, SARS-CoV-2 RNA was also detected in a mouth rinse, urine, and tear samples. This study was approved by the Medical Ethical Committee of The First Affiliated Hospital of Guangzhou Medical University (approval No. 2020-77). Results: SARS-CoV-2 mainly existed in sputum, nasal and throat swabs, and feces samples. Virus latency was longer in sputum and feces samples than in nasopharyngeal samples. IgG antibody response in respiratory samples was related to disease severity. Although droplets and aerosols are the major transmission routes for COVID-19, covert routes of transmission from asymptomatic patients, contaminated surfaces, and wastewater are also of interest. Conclusion: Our findings provide a solid foundation for developing prophylactic measures against SARS-CoV-2.

8.
2021 Abu Dhabi International Petroleum Exhibition and Conference, ADIP 2021 ; 2021.
Article in English | Scopus | ID: covidwho-1789274

ABSTRACT

Affected by the Covid-19 pandemic and low oil prices, OPEC members were forced to curtail production. The H oilfield in Iraq commenced production curtailment in early March 2020 and then oil production gradually decreased. By the end of 2020, production was less than one-third of the rate before curtailment. There are multiple sets of oil-bearing formations in the H Oilfield vertically. The developed oil reservoirs have a total of more than three hundreds development wells. The reservoir types are diverse, the relationship among multiphase fluids is complex, and the development methods are different. The reduction of the daily production will inevitably require a comprehensive strategy adjustment to cope with the new situation. Any intentional or unintentional shut-in has a price. Therefore, the key is how to reasonably control the production in many oil reservoirs and re-adjust the oil reservoir development plan at the minimum cost while meeting the overall changing production restriction target for each oil reservoir. In this study, the author established a simple and fast process for judging open and closed wells through years of experience in reservoir dynamic analysis and field management. Step 1: Wells are classified according to production characteristics. For pre-selected wells, some wells with unique functions that need to be opened and those that need to be closed for objective reasons should be excluded. Step 2: Conduct single well cost analysis with reference to production status. Respectively evaluate the performance of the production well under the state of opening and closing. Step 3: Establish the model with economic indicators as the objective function. According to different goals, the model established is slightly different. Step 4: Optimize the best solution based on actual needs. Solve the optimal solution under the target and optimize the number of reasonably configured wells in each reservoir. Through this process, combined with historical and current actual production conditions, different types of oil wells in all reservoirs are classified. Their priorities of reopening are evaluated to meet the needs of other production restriction targets and ensure the smooth transition of oilfield development. © Copyright 2021, Society of Petroleum Engineers

9.
5th International Conference on Crowd Science and Engineering, ICCSE 2021 ; : 61-67, 2021.
Article in English | Scopus | ID: covidwho-1774997

ABSTRACT

The distributed accounting method of blockchain, together with its decentralized and tamper proof characteristics, can solve the problem of lack of food safety traceability data and low credibility, which enable the traceability requirements of food chain traceability, problem food recall, food circulation information query. It also improves the food flow mode, and establishes a new food safety ecosystem. This paper innovatively integrates the principle of blockchain into the traceability and circulation process of Hebei cold chain food. In order to find the proportion and distribution of various types of commodities in the circulation of imported and domestic cold chain food in Hebei Province, the combination of qualitative and quantitative analysis methods, chi square test, association rules and other analysis methods are used. The results show that the demand for cold chain food in Hebei Province is mainly domestic food and supplemented by imported food. Cold chain poultry is the main need and other cold chain food is supplement. The flow of imported cold chain food is mainly from the surrounding provinces and cities. Furthermore, in the process of tracing the positive commodities, it is found that there are four main modes of commodity circulation in Hebei Province, namely, family model from farmer, wholesale market, new retail and multi-level sales model. The new retail and multi-level sales model fill the gap in the distribution and circulation of cold chain goods in Hebei Province. © 2021 ACM.

10.
6th International Conference on Electromechanical Control Technology and Transportation, ICECTT 2021 ; 12081, 2022.
Article in English | Scopus | ID: covidwho-1731248

ABSTRACT

With the promotion of electrification of transportation, fuel cell electric vehicles (FCEVs) begin to flourish in recent years. FCEVs operate with zero emission and excellent fuel economy, but high cost and incomplete infrastructure hinder the popularization further. Targeting resources are poured into this area by some governments worldwide. To foster the development, it is essential to study the use of FCEVs. Based on the Service and Management center for EVs (SMC-EV), this work conducts a statistical analysis of the market scales, the operation conditions, such as user login statistics, driving distance and refueling behavior and the impact of the occurrence of the Covid-19 pandemic. The analysis results provide essential support to predict the subsequent development of FCEVs and guide the policymaking and the construction of hydrogen refueling stations. © 2022 SPIE. All rights reserved.

11.
Journal of Acute Disease ; 11(1):1-11, 2022.
Article in English | EMBASE | ID: covidwho-1699574

ABSTRACT

Objective: To systematically evaluate the incidence of adverse reactions to coronavirus disease 2019 (COVID-19) vaccination. Methods: We systematically searched PubMed, Embase, The Cochrane Library, Web of Science, CNKI, WanFang Data, and VIP Database from the inception of each database to August 31, 2021. Randomized controlled clinical trials (RCTs) on the safety of different types of COVID-19 vaccines were retrieved and analyzed. A random or fixed-effects model was used with an odds ratio as the effect size. The quality of each reference was evaluated. The incidence of the adverse reactions of the placebo group and the vaccination group was compared. Heterogeneity and publication bias were taken care of by meta-regression and sub-group analyses. Results: A total of 13 articles were included, with 81 287 subjects. Compared with the placebo group, the vaccination group showed a higher combined risk ratio (RR) of total adverse reactions (RR=1.67, 95% CI: 1.46-1.91, P<0.01), local adverse reactions (RR=2.86, 95% CI: 2.11-3.87, P<0.01), systemic adverse reactions (RR=1.25, 95% CI: 0.92-1.72, P=0.16), pain (RR=2.55, 95% CI: 1.75-3.70, P<0.01), swelling (RR=4.16, 95% CI: 1.71-10.17, P=0.002, fever (RR=2.34, 95% CI: 1.84-2.97, P<0.01), fatigue (RR=1.36, 95% CI: 1.32-1.41, P<0.01) and headache (RR=1.22, 95% CI: 1.18-1.26, P<0.01). The subgroup analysis showed the incidence of adverse reactions of the vaccination group after injection of the three COVID-19 vaccines (inactivated viral vaccines, mRNA vaccines and adenovirus vector vaccines) was higher than that of the placebo group, and the difference between the placebo group and the vaccination group in the mRNA vaccine subgroup and the adenovirus vector vaccine subgroup was statistically significant (P<0.01). The incidence of adverse reactions after injection of COVID-19 vaccine in subgroups of different ages was significantly higher than that in the placebo group (P<0.01). Conclusions: COVID-19 vaccines have a good safety, among which adenovirus vector vaccine has the highest incidence of adverse reactions. Both adolescents and adults vaccinated with novel coronavirus vaccine have a certain proportion of adverse reactions, but the symptoms are mild and can be relieved by themselves. Our meta-analysis can help boost global awareness of vaccine safety, promote mass vaccination, help build regional and global immune barriers and effectively curb the recurrency of COVID-19.

12.
Chinese General Practice ; 25(4):424-431, 2022.
Article in Chinese | Scopus | ID: covidwho-1698661

ABSTRACT

Background: Under the conditions of regular containment of COVID-19 epidemic, the levels of core competencies in emergency management of community public health emergency responders are directly associated with the effectiveness of management of public health emergencies. However, there are few studies on core competencies in emergency management of public health emergencies and areas in demand for improvement in community public health emergency responders.Objective: To examine the core competencies in emergency management of COVID-19 pandemic, and associated factors as well as areas in demand for improvement within community public health emergency responders from Zhejiang Province. Methods: Using the Core Response Competence Index System for Infectious Disease Emergencies among Medical Staff as a reference, we developed a questionnaire consisting of three parts: demographic and COVID-19 containment status, Core Competencies for Emergency Management of Public Health Emergencies(CCEMPHE), and areas in demand for improvement, and used it to conduct an online survey with 749 community public health emergency responders selected from six counties(districts) of Zhejiang using stratified cluster sampling in September 2020. Results: The survey achieved a response rate of 93.3%(699/749). The average score of CCEMPHE for the respondents was(118.38±27.60), with a scoring rate of 62.3%. The scoring rates of three dimensions of the CCEMPHE from high to low were prevention ability(66.4%), preparedness ability(63.7%) and rescue ability(62.0%). Multiple linear regression analysis showed that education background(b=4.55), physical quality for emergency work(b=9.26), experiences of participating in developing emergency plan/technical proposal(b=6.43), attending emergency training(b=6.35), field epidemiology training(b=4.62), on-site emergency disposal experience(b=5.32), the number of theoretical trainings related to COVID-19(b=4.29), and the number of COVID-19 containment projects involved in(b=1.16), were associated with the core competencies in emergency management of COVID-19 pandemic in community public health emergency responders(P< 0.05). In terms of areas in demand for improvement, the knowledge related to health emergency response and management(4.09±0.86)was in highest demand, on-site guidance(4.17±0.84)was the most popular training form and short-term training(3.93±0.92)was the most suitable training method. Conclusion: The community public health emergency responders in Zhejiang Province had lower intermediate CCEMPHE, and a high demand for improvement. To improve the core competencies in emergency management of infectious disease emergencies of community public health emergency responders, it is suggested to health administrators to strengthen practice trainings for these responders based on their needs, especially on-site practice trainings, with a focus on practical skill training. Copyright © 2022 by the Chinese General Practice.

13.
2021 ASEE Virtual Annual Conference, ASEE 2021 ; 2021.
Article in English | Scopus | ID: covidwho-1695907

ABSTRACT

The shift to distance learning in response to the COVID-19 pandemic has presented teachers and students with several challenges. Teachers have found themselves quickly creating distance learning materials to provide equal or greater educational opportunity and engagement as in-person instruction. This shift is met with parallel increased demand on students to independently manage their learning and coursework with the absence of in-person supervision, support, and peer interaction. In this work, we describe our approach and observations in transitioning Discovery, a secondary student science, technology, engineering, and mathematics (STEM) education program, to a virtual platform. Developed by graduate students in 2016, Discovery was designed to engage secondary students in semester-long inquiry-based projects within the context of biomedical engineering. Projects are designed to foster and reinforce critical thinking skills required for post-secondary study. Throughout the semester, students design and execute experiments within post-secondary laboratories with instructional support from both their teachers and graduate student volunteers. In response to university teaching space closures in early 2020, we developed and delivered a virtual offering of Discovery. In contrast to in-person delivery, this initial virtual offering placed greater emphasis upon quantitative analysis rather than experimental design and execution. Access to virtual laboratory simulations was provided as a substitute for in-laboratory skill development. While overall assessment of student (survey instrument) and teacher (interviews) experiences revealed a highly positive perception of the program experience, areas for improvement were also highlighted. Many students reported struggling with motivation to keep up with course materials and soft deadlines (60%) as well as the lack of guidance provided by in-person mentor and teacher interactions (50%). Teacher interviews echoed quantified student perceptions, but further identified lamentation at the loss of student-driven, open-ended, and iterative problem-solving opportunities typically afforded by Discovery. Consequently, we developed an adjusted virtual program for the Fall 2020 term. The redesigned program reintroduced the open-ended aspect of previous in-person projects, and rather than including access to commercially available virtual laboratory simulation, greater focus was placed on design of experimental procedures that were evaluated and simulated by graduate students. Additionally, greater care was taken to discretize project components and deliverable deadlines to provide enhanced structure and guidance for students. We observed this updated program structure to similar outcomes of in-person offerings. A slight majority (51.4%) of Fall 2020 students achieved higher grades for Discovery deliverables than other class assessments. In post-program surveys, ~49% of students indicated they are more likely to pursue STEM courses, ~89% would participate in the program again, and ~78% responded that the experience made them more comfortable with completing university or college level laboratory work. While these results were encouraging, comparisons to previous in-person outcomes and analysis of teacher experiences (interviews) highlighted persistent gaps in student experience while completing the program virtually. © American Society for Engineering Education, 2021

14.
10th International Conference on Frontier Computing, FC 2020 ; 747:1337-1344, 2021.
Article in English | Scopus | ID: covidwho-1626477

ABSTRACT

In order to “keep learning when class suspended” during the epidemic caused by coronavirus disease (COVID-19), the teaching team of clinical microbiology course makes full use of information technology to innovate the teaching mode and introduce the PDCA circulation in the field of quality management into online teaching. The teaching design is made from the four stages of plan, do, check and act. This method advocates that students should learn by themselves before class, actively discuss in class, expand thinking after class and show their learning achievements in various ways, so as to implement the “student-centered” concept. The teaching team can achieve online knowledge transfer on the basis of closed-loop integrity and continuity circulation, which provides a reference for improving the information technology teaching ability of the teaching team. © 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

15.
Epidemiology and Infection ; 2021.
Article in English | EMBASE | ID: covidwho-1586095

ABSTRACT

COVID-19 elicits a range of different responses in patients and can manifest into mild to very severe cases in different individuals, depending on many factors. We aimed to establish a prediction model of severe risk in COVID-19 patients, to help clinicians achieve early prevention, intervention, and aid them in choosing effective therapeutic strategy. We selected confirmed COVID-19 patients who admitted to First Hospital of Changsha city between January 29 and February 15, 2020 and collected their clinical data. Multivariate logical regression was used to identify the factors associated with severe risk. These factors were incorporated into the nomogram to establish the model. The ROC curve, calibration plot and decision curve were used to assess the performance of the model. 228 patients were enrolled and 33 (14.47%) patients developed severe pneumonia. Univariate and multivariate analysis showed that shortness of breath, fatigue, creatine kinase, lymphocytes and h CRP were independent factors for severe risk in COVID-19 patients. Incorporating age, COPD and these factors, the nomogram achieved good concordance indexes of 0.89 (95% CI: 0.832-0.949), and well-fitted calibration plot curves (Hosmer-Lemeshow test: P=0.97). The model provided superior net benefit when clinical decision thresholds were between 15-85% predicted risk. Using the model, clinicians can intervene early, improve therapeutic effects and reduce the severity of COVID-19, thus ensuring more targeted and efficient use of medical resources.

17.
Biotechnology Law Report ; 40(5):334-338, 2021.
Article in English | Web of Science | ID: covidwho-1532405

ABSTRACT

A novel coronavirus pneumonia broke out in early 2020 in China. In order to find a certain cure, China has turned its attention to Remdesivir, which is produced by Gilead. At the initial stage, China placed high expectations on this drug, and urgently approved phase III clinical trial applications. As the epidemic in China slowed, the development of Remdesivir clinical trials also encountered the problem of insufficient number of participants, and some trials were forced to terminate early. The recent clinical trial results show that the efficacy of Remdesivir is uncertain, which has made the Chinese government's attitude towards approving the marketing authority of Remdesivir become cautious. Based on this information, we expect that it will be difficult for Remdesivir to successfully list in China in the future, and there are also some competitors try to enter the Chinese market as imported drugs. But in other ways, China can cooperate with Gilead and other manufacturing companies to solve global public health problems.

18.
Zhonghua Shao Shang Za Zhi ; 37(11): 1070-1077, 2021 Nov 20.
Article in Chinese | MEDLINE | ID: covidwho-1526870

ABSTRACT

Objective: To observe the application effects of a standard communication system-based continuous home remote visit mode in the management of visits to severely burned patients in the post-pandemic era of coronavirus disease 2019 (hereinafter referred to as post-pandemic era). Methods: A retrospective cohort study was conducted. A total of 69 severely burned patients who met the inclusion criteria and were admitted to the First Affiliated Hospital of Army Medical University (the Third Military Medical University) from February to December, 2020 and their 69 family members were recruited into this study. According to the difference of visit model, 33 severely burned patients who were admitted into burn intensive care unit (BICU) from February to June, 2020 and received completely restricted visits according to the requirements for epidemic prevention and control and their corresponding 33 family members were included into conventional visit group; 36 severely burned patients who were admitted into BICU from July to December, 2020 and received the standard communication system-based continuous home remote visits and their 36 corresponding family members were recruited into remote visit group. The family members in conventional visit group could only communicate with the primary nurses by telephone, while the patients and family members in remote visit group could communicate with the primary nurses, responsible doctors, rehabilitation therapists, and nutrition therapists through WeChat video call. The survey results of general information questionnaire and Hamilton Anxiety Scale (HAMA) scores of two groups of patients and their family members at BICU admission of patients, HAMA scores of the two groups of patients and their family members in the second week of BICU admission and at discharge from BICU of patients, the scores of the Visiting Effect Evaluation Scale of the two groups of patients and their family members and the scores of Chinese version of Critical Care Family Satisfaction Survey (C-CCFSS) of the two groups of family members at discharge from BICU, and the scores of Satisfaction Survey and Evaluation Scale During Hospitalization of patients within the first week after the discharge of patients from BICU were compared. Data were statistically analyzed with chi-square test, Fisher's exact probability test, and Mann-Whitney U test. Results: In remote visit group, there were 29 males and 7 females in patients, aged 48 (34, 53) years, and 15 males and 21 females in family members, aged 45 (30, 48) years. In conventional visit group, there were 24 males and 9 females in patients, aged 49 (38, 54) years, and 9 males and 24 females in family members, aged 44 (35, 48) years. At BICU admission of patients, the HAMA scores of the two groups of patients and family members were both similar (P>0.05). The total HAMA scores of patients and family members in remote visit group were significantly lower than those in conventional visit group in the second week when the patients were admitted to BICU (Z=-3.195, -3.018, P<0.01) and discharged from BICU (Z=-2.118, -2.380, P<0.05). At discharge from BICU of patients, the scores of each dimension in Visiting Effect Evaluation Scale of the patients in the two groups were similar (P>0.05); while scores of 3 dimensions including patient safety information, diagnosis and treatment quality information, and psychological support information in Visiting Effect Evaluation Scale of family members in remote visit group were significantly higher than those in conventional visit group (Z=-2.372, -2.209, -2.174, P<0.05), and only the scores of visit perception of family members were close to those in conventional visit group (P>0.05). At discharge from BICU of patients, the C-CCFSS scores of the family members in remote visit group was 99 (98, 108), which were significantly higher than 98 (97, 100) in conventional visit group (Z=-2.545, P<0.05). Within the first week after the discharge of patients from BICU, the scores of Satisfaction Survey and Evaluation Scale During Hospitalization of patients in remote visit group were 99 (98, 100), which were significantly higher than 96 (94, 98) in conventional visit group (Z=-5.213, P<0.01). Conclusions: In the management of visits to severely burned patients in the post-pandemic era, application of the standard communication system-based continuous home remote visit mode can improve the visit effect and satisfaction, and effectively alleviate the anxiety of patients and their family members.


Subject(s)
COVID-19 , Pandemics , Communication , Female , Humans , Male , Retrospective Studies , SARS-CoV-2
19.
IEEE Transactions on Automation Science and Engineering ; 2021.
Article in English | Scopus | ID: covidwho-1515167

ABSTRACT

During the outbreak of epidemics such as coronavirus disease (COVID-19), the local hospitals often withstand a sharp increase of patient influx, which renders the healthcare system on the verge of collapse. To alleviate the situation, the effective allocation of scarce medical resources during the pandemic plays a vital role. The essence of the healthcare system in time of emergency is to stay functional, and to be able to diagnose and hospitalize as many patients as possible. Fangcang shelter hospital, as a novel way to temporarily increase the capacity of the local healthcare system, is proven to be effective against the COVID-19 pandemic. To improve the performance of the healthcare system with Fangcang, many practical factors need to be taken into account, such as the patient deterioration during waiting to be admitted, the referral mechanism according to the severity of the patients, and the selective admission regulations. To address the high volatility and time-varying feature of the COVID-19, a multistage and multi-type medical service network model is established, and a dynamic allocation strategy of the medical resources at each stage is proposed based on a stochastic optimization problem, which is then solved via the fluid queueing approximation. Combined with the real data collected from Wuhan, it is revealed that the proposed algorithm could help with the allocation of medical resources during the outbreak of epidemics. Even with limited medical resources available, the method could still maintain a guaranteed service level while keeping the healthcare system operational. Furthermore, the simulation analysis validates that our method can effectively allocate medical resources at each stage, so as to stabilize the system performance and fulfill the medical demand for multiple types of patients. IEEE

20.
6th International Congress on Information and Communication Technology, ICICT 2021 ; 235:735-743, 2022.
Article in English | Scopus | ID: covidwho-1469676

ABSTRACT

Pandemics like COVID-19 confine and isolate people due to the necessary physical distancing, lockdown or quarantine countermeasure, which can in particular deteriorate the social environment for older people. Chatbots are a significant part of COVID-19 countermeasures for providing digital mental health services to older people in order to ‘keep them alive’ during the fight against this pandemic. This study performs a critical assessment of the state of the art and the research gaps regarding the topic and proposes high-level, strategic solutions to help researchers and practitioners speed up the corresponding project planning and mitigate the potential development risks. The design of mental health chatbots is grounded in the fields of psychology and culture and utilizes the most advanced information and communication technologies including conversational interfaces, Artificial Intelligence, Machine Learning and Natural Language Processing. A strong interdisciplinary and intercultural collaboration is essential to better understand the mental hardships of older people during such times and take effective measures to alleviate their suffering. Research in this field provides long-term, sustainable value to our society. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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