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1.
Front Psychiatry ; 13: 883590, 2022.
Article in English | MEDLINE | ID: covidwho-1855449

ABSTRACT

Background: A number of studies have documented that coronavirus disease 2019 (COVID-19) brought more negative impact on the physical and psychological functioning of frontline healthcare workers. Especially, sleep quality was focused. This study aimed to investigate the sleep quality of frontline healthcare workers, risk factors for sleep quality, and the effect of Tai Chi training. Methods: A total of 98 frontline healthcare workers were recruited, coming from the infection department, fever clinic, laboratory, and medical imaging department in a COVID-19-designated hospital in Shanghai. Of them, 50 participated in a 2-week intervention and were randomized to receive a Tai Chi training or relaxation training. Participants were assessed at baseline, 7 and 14 days after participation. Demographic information, sleep quality, and anxiety were measured by using the demographic questionnaire, Pittsburgh Sleep Quality Index (PSQI) and Beck Anxiety Inventory (BAI). Results: 13.3% participants were above the cut-off score (>10) for the PSQI. Regression analysis showed gender, age, working years, and job category had effect on sleep quality. Compared to the control group, participants in the Tai Chi training group had lower scores on both PSQI (p < 0.05) and BAI (p < 0.01) after the 2-week intervention. Conclusion: It was demonstrated that poor sleep quality existed in the frontline healthcare workers, which was related to gender, age, working years, and job category. Tai Chi training can dramatically improve their sleep quality and reduce anxiety symptoms.

2.
Transl Psychiatry ; 12(1): 180, 2022 05 03.
Article in English | MEDLINE | ID: covidwho-1821577

ABSTRACT

The long-term health consequences of the COVID-19 pandemic on health care workers (HCWs) are largely unclear. The purpose of the present study was to investigate the development of posttraumatic stress disorder (PTSD) in HCWs in a longitudinal manner. Additionally, we further explored the role of risk perception in the evolution of PTSD over time based on a one-year follow-up study. HCWs were recruited from hospitals in Guangdong, China. Demographic information, the PTSD checklist for DSM-5 (PCL-5) and the risk perception questionnaire were obtained online at two different time points: May to June 2020 (T1), with 317 eligible responses, and June 2021 (T2), with 403 eligible responses. Seventy-four HCWs participated in the survey at both T1 and T2. The results revealed that (1) the PTSD prevalence rate in the HCWs (cut-off = 33) increased from 10.73% at T1 to 20.84% at T2, and the HCWs reported significantly higher PTSD scores at T2 than at T1 (p < 0.001); (2) risk perception was positively correlated with PTSD (p < 0.001); and (3) PTSD at T1 could significantly positively predict PTSD at T2 (ß = 2.812, p < 0.01), and this longitudinal effect of PTSD at T1 on PTSD at T2 was mediated by risk perception at T2 (coefficient = 0.154, 95% CI = 0.023 to 0.297). Our data provide a snapshot of the worsening of HCWs' PTSD along with the repeated pandemic outbreaks and highlight the important role of risk perception in the development of PTSD symptoms in HCWs over time.


Subject(s)
COVID-19 , Stress Disorders, Post-Traumatic , Follow-Up Studies , Health Personnel , Humans , Pandemics , Perception , Stress Disorders, Post-Traumatic/diagnosis , Stress Disorders, Post-Traumatic/epidemiology
3.
BMJ Open ; 12(3): e049749, 2022 03 30.
Article in English | MEDLINE | ID: covidwho-1769910

ABSTRACT

OBJECTIVE: The COVID-19 pandemic is not only a traumatic event, but a collective stressor unfolding over time, causing devastating implications for the mental health. This study aimed to shed light on the mental health status of patients with rheumatic disease (RD) during the massive outbreak of COVID-19 in China, especially the prevalence and severity of post-traumatic stress disorder (PTSD) compared with healthy individuals. METHODS: A total of 486 patients with RD and 486 age-matched and sex-matched healthy individuals were recruited into the study. For each participant, we collected demographic and clinical characteristics data. The PTSD Checklist for DSM-5 (PCL-5) and four items from the Pittsburgh Sleep Quality Index (PSQI) were used to investigate the prevalence and severity of PTSD and sleep quality, respectively. RESULTS: Compared with healthy control subjects (n=486), patients with RD (n=486) had a higher prevalence of PTSD (12.1% vs 4.1%; p<0.001). Higher total scores on the PCL-5 and on all four items from the PSQI (p≤0.001) were also observed. Female, old age, poor sleep quality, long duration of RD, poor subjective evaluation of the disease and pessimistic subjective perception of the epidemic were identified as risk factors of PTSD in patients with RD during the COVID-19 epidemic. CONCLUSION: During the COVID-19 outbreak, patients with RD presented a higher prevalence and severity of PTSD and showed more sleep disturbances. Our findings confirm the importance of psychological assessment and mental healthcare out of regular clinical care for patients with RD during the pandemic.


Subject(s)
COVID-19 , Rheumatic Diseases , Stress Disorders, Post-Traumatic , COVID-19/epidemiology , Case-Control Studies , China/epidemiology , Cross-Sectional Studies , Female , Humans , Pandemics , Rheumatic Diseases/complications , Rheumatic Diseases/epidemiology , Stress Disorders, Post-Traumatic/epidemiology , Stress Disorders, Post-Traumatic/etiology , Stress Disorders, Post-Traumatic/psychology
4.
EuropePMC; 2020.
Preprint in English | EuropePMC | ID: ppcovidwho-315662

ABSTRACT

The outbreak of Coronavirus Disease 2019 (COVID-19) pandemic is leading to widespread emotional distress such as post-traumatic stress disorder (PTSD). Our objective was to investigate the gender differences in PTSD symptoms (PTSS) among COVID-19 symptomatic patients over time caused by delayed medical visit. We investigated 258 confirmed cases of COVID-19 from two designated hospitals in Wuhan from 26 February to 16 March. PTSS was measured by PTSD Checklist for DSM-5 (PCL-5). Demographics and time interval from symptom onset to the first medical visit were also collected. The results show that 48 of 258 participants (18.6 %) met the criteria of PTSD symptoms. Males had significantly higher PCL-5 scores when time interval was 7 days or more compared with less than 7 days (22.18 vs. 15.11, t=-2.280, P<0.05), whereas no such significant time effect was found in females, regardless of the severity of the disease. The present study emphasizes the significant effect of time course on PTSS only in male. It is suggested that policy makers and health services should pay more attention to PTSD in male, and call on male to seek medical treatment as soon as developing symptoms of coronavirus disease if local medical conditions permitted.

5.
EuropePMC; 2020.
Preprint in English | EuropePMC | ID: ppcovidwho-324167

ABSTRACT

Background: The COVID-19 pandemic is not only a traumatic event, but a collective stressor unfolding over time, causing alarming implications for the mental health. This study aims to shed light on the mental health status of patients with rheumatic disease (RD) during the massive outbreak of COVID-19 in China, especially the prevalence and severity of post-traumatic stress disorder (PTSD) compared with the levels in healthy people. Methods: A questionnaire survey was conducted in a cross-sectional study of 486 RD patients and 486 healthy control subjects. We collected participants’ demographic and clinical characteristics and surveyed the prevalence and severity of PTSD and sleep quality in the samples using the PTSD Checklist for DSM-5 (PCL-5) and 4 items from the Pittsburgh Sleep Quality Index (PSQI). Findings: Compared with healthy control subjects (n=486), RD patients (n=486) had a higher prevalence of PTSD (12·1% vs. 4·1%;p<0·001). They also had higher total scores on the PCL-5 and on all four items from the PSQI (p≤ 0·001). Female gender, old age, poor sleep quality, long duration of RD, poor subjective evaluation of the disease and pessimistic subjective perception of the epidemic were identified as risk factors for PTSD in RD patients during the COVID-19 epidemic. Interpretation: During the COVID-19 outbreak, RD patients presented a higher prevalence and severity of PTSD and more sleep disturbances. Our findings confirm the importance of psychological assessment and mental health care in addition to regular clinical care for RD patients during the pandemic. Funding: National Natural Science Foundation of China, China Ministry of Science and Technology, Shanghai Municipal Key Clinical Specialty Fund.Declaration of Interests: The authors declare no competing interests.Ethics Approval Statement: This study was approved by the Human Research Ethics Committee of Changzheng Hospital, and informed consent was obtained from all participants.

6.
Nat Sci Sleep ; 13: 1519-1531, 2021.
Article in English | MEDLINE | ID: covidwho-1435685

ABSTRACT

BACKGROUND: The outbreak of COVID-19 has developed into a pandemic. Data are required that specifically address the psychological consequences in COVID-19 confirmed patients. This study mainly aimed to examine posttraumatic stress disorder (PTSD) symptoms and sleep quality among COVID-19 confirmed patients during hospitalization. METHODS: An observational study was conducted in two designated hospitals in Wuhan, China. Data were collected from 190 patients hospitalized with laboratory-confirmed COVID-19 infection between February 10, 2020 and March 13, 2020. RESULTS: The mean age of the 190 confirmed patients was 55.7 years (SD = 13.7), of which 96 (50.5%) were female and 88 (46.3%) had family members or acquaintances infected with COVID-19. Lymphocytopenia was presented in 62 (32.6%) patients and 25 (13.2%) patients showed oxygen desaturation. The prevalence of high PTSD symptoms was 22.6% among the 190 patients. The median time from symptom onset to first medical visit and hospitalization was 2 days (IQR, 1-5) and 16 days (IQR, 10-27), respectively. Patients' PTSD symptoms were positively related to the time from symptom onset to first medical visit (r = 0.156, p < 0.05) and hospitalization (r = 0.181, p < 0.01). There were significant correlations between sleep quality and PTSD symptoms (r = 0.312-0.547, p < 0.01). CONCLUSION: The prevalence of high PTSD symptoms was 22.6% among hospitalized COVID-19 patients. Early diagnosis and treatment of COVID-19 symptoms are beneficial to infected patients both physically and psychologically. With the recovery of physical symptoms, psychological intervention is desired to promote the trauma recovery in COVID-19 patients.

7.
Front Psychiatry ; 12: 560602, 2021.
Article in English | MEDLINE | ID: covidwho-1259393

ABSTRACT

Background: COVID-19 has taken a huge toll on medical resources and the economy and will inevitably have an impact on public mental health. Post-traumatic stress disorder (PTSD), as the most common mental illness after an epidemic, must be seriously addressed. This study aimed to investigate the subjective fear of the Chinese general public during COVID-19 and to explore how it affected the development of PTSD. Methods: An online questionnaire survey was conducted among 1,009 people from January 30 to February 14, 2020 (about 1 month after the COVID-19 outbreak). The subjective fear was measured by a self-reported single-choice question. Four items from the Pittsburgh Sleep Quality Index (PSQI) were selected to measure the subjects' sleep quality. Their post-traumatic stress symptoms (PTSS) were measured by the PTSD Checklist for DSM-5 (PCL-5). Pearson correlation, hierarchical multivariate regression analysis, multiple mediator model, and bootstrapping were used in statistical analyses. Results: Different people showed different levels of subjective fear in response to the outbreak. There was a significant positive correlation between subjective fear and the total score of PCL-5 (R = 0.513, P < 0.01), meaning that the higher the degree of subjective fear, the more severe the symptoms of post-traumatic stress are. Subjective fear was an important predictor of PTSS, accounting for 24.3% of the variance. The total effect of subjective fear on PCL-5 scores was significant (total effect = 7.426, SE = 0.405, 95% CI = 6.631-8.221). The total indirect effect of subjective fear on PCL-5 scores through sleep quality was also significant (total indirect effect = 1.945, SE = 0.258, 95% CI = 1.436-2.470). Conclusions: Subjective fear has an important predictive effect on PTSS. In addition to the direct effect, our findings firstly demonstrate the mediating role of sleep quality in the relationship between subjective fear and PTSS.

8.
Clin Psychol Psychother ; 28(5): 1146-1159, 2021 Sep.
Article in English | MEDLINE | ID: covidwho-1085672

ABSTRACT

The aim of current study was to investigate risk perception of COVID-19 pandemic, sleep quality and time change of leisure activity and their correlations with posttraumatic stress disorder (PTSD) in healthcare workers (HCWs) from four designated hospitals in China. Medical staffs (n = 317) from three designated hospitals in Guangdong Province and one designated hospital in Guangxi Province were surveyed on their demographic information, sleep quality and time change of leisure activity, risk perception of pandemic and PTSD symptoms (by using PTSD checklist for DSM-5 (PCL-5)). Hierarchical regression and structural equation model (SEM) were used to examine the correlated factors of PTSD. The prevalence of high level of PTSD symptoms (PCL-5 > =33, a probable diagnosis of PTSD) was 10.7%. Regression analysis found that risk perception (dread: ß = 0.142, p < 0.01; familiarity: ß = 0.203, p < 0.01), sleep quality (ß = 0.250, p < 0.001), time change of leisure activity (ß = -0.179, p < 0.01), were independently correlated with PTSD severity, which was further confirmed by SEM. Locations of COVID-19-related hazards were significant different in cognitive map of risk perception between groups with high and low levels of PTSD symptoms. Risk perception of COVID-19 pandemic influenced PTSD symptoms in HCWs. Adequate time for leisure activity and good sleep quality protected some HCWs against PTSD symptoms under the influence of pandemic. More researches were warranted to understand the path from pre-factors of risk perception to its psychological consequences among HCWs.


Subject(s)
COVID-19 , Stress Disorders, Post-Traumatic , China/epidemiology , Cross-Sectional Studies , Health Personnel , Hospitals , Humans , Pandemics , Perception , SARS-CoV-2 , Stress Disorders, Post-Traumatic/epidemiology
9.
J Affect Disord ; 283: 123-129, 2021 03 15.
Article in English | MEDLINE | ID: covidwho-1051729

ABSTRACT

BACKGROUND: To examine the prevalence of and risk factors for acute posttraumatic stress disorder (PTSD) shortly after the massive outbreak of COVID-19 in China. METHODS: An online anonymous survey was conducted between 30 January and 3 February, 2020. The survey included two self-administered questionnaires: one collected personal information (gender, age, education background), current location, recent epidemic area contact history, the classification of population, and subjective sleep quality; the other was the PTSD Checklist for DSM-5 (PCL-5). RESULTS: A total of 2091 Chinese participated in the current study. The prevalence of PTSD among the Chinese public one month after the COVID-19 outbreak was 4.6%. Multiple linear regression analysis revealed that gender (p < 0.001), epidemic area contact history (p = 0.047), classification of population (p < 0.001), and subjective sleep quality (p < 0.001) could be regarded as predictors for PTSD. LIMITATIONS: First, the majority of participants in this study were the general public, with confirmed or suspected patients being a small part. Second, the measurement of PTSD in this study might be vulnerable to selection bias because of an online self-report study, such as participants' recruitment. Third, the prevalence of PTSD in this study was estimated by an online questionnaire rather than a clinical interview. CONCLUSIONS: The results suggested that some Chinese showed acute PTSD during the COVID-19 outbreak. Therefore, comprehensive psychological intervention needs further implementation. Furthermore, females, people who had recent epidemic area contact history, those at high risk of infection or with poor sleep quality deserve special attention.


Subject(s)
COVID-19 , Stress Disorders, Post-Traumatic , China/epidemiology , Cross-Sectional Studies , Disease Outbreaks , Female , Humans , Prevalence , Risk Factors , SARS-CoV-2 , Stress Disorders, Post-Traumatic/epidemiology , Surveys and Questionnaires
10.
Sci Rep ; 10(1): 22463, 2020 12 31.
Article in English | MEDLINE | ID: covidwho-1003322

ABSTRACT

The impact of 2019 coronavirus disease (COVID-19) outbreak on mental health was of widespread concern recently. The present study aimed to exam sleep quality and posttraumatic stress symptoms (PTSS) and potential influence factors in the first phases of COVID-19 massive outbreak in China. A snowball sampling technique was used and a total of 2027 Chinese participated in the present study. Demographic information, epidemic area contact history, sleep quality and PTSS data were collected with an internet-based cross-sectional survey. Results suggested that 59.7% participants were not fully satisfied with their sleep quality, and 50.9% participants had various degrees of short sleep duration problems. 44.1% and 33.0% participants had sleep disturbance and sleep onset latency problems. Also, the prevalence of PTSS reached 4.7% in the self-rating survey. Epidemic area contact history affected PTSS and latency onset of sleep under the influence of COVID-19. Epidemic area contact history and sleep quality had interaction effects on PTSS. The present study was one of the first to evaluate acute psychological responses and possible risk factors during the peak of COVID-19 in China and results indicate that keeping good sleep quality in individuals with pandemic exposure experiences is a way to prevent PTSS.


Subject(s)
COVID-19/pathology , COVID-19/psychology , Sleep Initiation and Maintenance Disorders/epidemiology , Stress Disorders, Post-Traumatic/epidemiology , Adult , Anxiety/epidemiology , China/epidemiology , Cross-Sectional Studies , Depression/epidemiology , Female , Humans , Male , Mental Health/statistics & numerical data , Middle Aged , SARS-CoV-2 , Sleep/physiology , Surveys and Questionnaires , Young Adult
11.
Gen Psychiatr ; 33(6): e100297, 2020.
Article in English | MEDLINE | ID: covidwho-955447
12.
Academic Journal of Second Military Medical University ; 41(3):303-306, 2020.
Article in Chinese | CAB Abstracts | ID: covidwho-829625

ABSTRACT

Coronavirus disease 2019 (COVID-19) was first reported in late December 2019, and then erupted in China. COVID-19 is characterized by strong infectivity and a high mortality rate. The public and medical staff are under great psychological pressure. Scholars at home and abroad have carried out researches on mental health during the outbreak of COVID-19. This article summarizes the current researches on mental health related to COVID-19 from three aspects: mental health policy, mental intervention measures and mental health of key population.

13.
Clin Psychol Psychother ; 27(3): 384-395, 2020 May.
Article in English | MEDLINE | ID: covidwho-626959

ABSTRACT

Corona virus disease 2019 (COVID-19) outbreak has attracted worldwide attention. The COVID-19 outbreak is unique in its rapid transmission and results in heavy stress for the front-line health care workers (HCWs). The current study aimed to exam posttraumatic stress symptoms (PTSSs) of HCWs fighting for the COVID-19 and to evaluate their sleep quality after 1-month stressful suffering. Three hundred seventy-seven HCWs working in different provinces of China participated in the survey between February 1 and 5. The demographic information was collected first. Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5) and the Pittsburgh Sleep Quality Index (PSQI) were selected to measure PTSSs and sleep quality. Results showed that 1 month after the outbreak, the prevalence of PTSSs was 3.8% in HCWs. Female HCWs were more vulnerable to PTSSs with hazard ratio of 2.136 (95% CI = 1.388-3.286). HCWs with higher exposure level also significantly rated more hyperarousal symptoms (hazard ratio = 4.026, 95% CI = 1.233-13.140). There was a significant difference of sleep quality between participants with and without PTSSs (z value = 6.014, p < .001) and among different groups with various contact frequencies (chi-square = 7.307, p = .026). Path analysis showed that there was a significant indirect effect from exposure level to PTSSs through sleep quality (coefficient = 1.750, 95% CI of Boostroop test = 0.543-2.998). In summary, targeted interventions on sleep contribute to the mental recovery during the outbreak of COVID-19. Understanding the mental health response after a public health emergency might help HCWs and communities prepare for a population's response to disaster.


Subject(s)
Coronavirus Infections/psychology , Health Personnel/psychology , Health Personnel/statistics & numerical data , Pneumonia, Viral/psychology , Stress Disorders, Post-Traumatic/epidemiology , Stress Disorders, Post-Traumatic/prevention & control , Adolescent , Adult , Betacoronavirus , COVID-19 , China/epidemiology , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Pandemics , SARS-CoV-2 , Young Adult
15.
Psychol Trauma ; 12(S1): S3-S5, 2020 Aug.
Article in English | MEDLINE | ID: covidwho-598503

ABSTRACT

The study investigated the quarantine of COVID-19 and its impact on mental health. The results showed that there was a significant difference in PTSD Checklist for DSM-5 scores between the quarantine group and the non-quarantine group. As a result, the mental health of residents in mandatory quarantine zones urgently requires intervention. (PsycInfo Database Record (c) 2020 APA, all rights reserved).


Subject(s)
Coronavirus Infections , Fear , Pandemics , Pneumonia, Viral , Quarantine , Sleep Wake Disorders , Stress Disorders, Post-Traumatic , Adult , COVID-19 , China/epidemiology , Coronavirus Infections/prevention & control , Coronavirus Infections/psychology , Fear/psychology , Health Surveys , Humans , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Pneumonia, Viral/psychology , Quarantine/psychology , Quarantine/statistics & numerical data , Severity of Illness Index , Sleep Wake Disorders/epidemiology , Sleep Wake Disorders/etiology , Sleep Wake Disorders/psychology , Stress Disorders, Post-Traumatic/epidemiology , Stress Disorders, Post-Traumatic/etiology , Stress Disorders, Post-Traumatic/psychology
16.
Biodes Manuf ; : 1-4, 2020 May 11.
Article in English | MEDLINE | ID: covidwho-232677

ABSTRACT

We present an example of applying 'need-driven' product design principle to the development of a rapid test kit to detect SARS-COV-2 (COVID-19). The tests are intended for use in the field and, longer term, for home use. They detect whether a subject is currently infected with the virus and is infectious. The urgent need for large numbers of tests in field setting imposes constraints such as short test time and lack of access to specialist equipment, laboratories and skilled technicians to perform the test and interpret results. To meet these needs, an antigen test based on RT-LAMP with colorimetric readout was chosen. Direct use of swab sample with no RNA extraction was explored. After extensive experimental study (reported elsewhere), a rapid test kit has been fabricated to satisfy all design criteria.

17.
Psychiatry Res ; 287: 112921, 2020 05.
Article in English | MEDLINE | ID: covidwho-8728

ABSTRACT

The outbreak of COVID-19 in China in December 2019 has been identified as a pandemic and a health emergency of global concern. Our objective was to investigate the prevalence and predictors of posttraumatic stress symptoms (PTSS) in China hardest-hit areas during COVID-19 outbreak, especially exploring the gender difference existing in PTSS. One month after the December 2019 COVID-19 outbreak in Wuhan China, we surveyed PTSS and sleep qualities among 285 residents in Wuhan and surrounding cities using the PTSD Checklist for DSM-5 (PCL-5) and 4 items from the Pittsburgh Sleep Quality Index (PSQI). Hierarchical regression analysis and non-parametric test were used to analyze the data. Results indicated that the prevalence of PTSS in China hardest-hit areas a month after the COVID-19 outbreak was 7%. Women reported significant higher PTSS in the domains of re-experiencing, negative alterations in cognition or mood, and hyper-arousal. Participants with better sleep quality or less frequency of early awakenings reported lower PTSS. Professional and effective mental health services should be designed in order to aid the psychological wellbeing of the population in affected areas, especially those living in hardest-hit areas, females and people with poor sleep quality.


Subject(s)
Coronavirus Infections/psychology , Pneumonia, Viral/psychology , Stress Disorders, Post-Traumatic/etiology , Adult , Betacoronavirus , COVID-19 , China/epidemiology , Coronavirus Infections/epidemiology , Disease Outbreaks , Female , Humans , Male , Pandemics , Pneumonia, Viral/epidemiology , Prevalence , SARS-CoV-2 , Sex Factors , Sleep Initiation and Maintenance Disorders/epidemiology , Surveys and Questionnaires , Young Adult
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