Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 58
Filter
Add filters

Year range
1.
Rev Esp Quimioter ; 2022 Nov 02.
Article in English | MEDLINE | ID: covidwho-2101032

ABSTRACT

We do not know the precise figure for solid organ tumors diagnosed each year in Spain and it is therefore difficult to calculate whether there has been a decrease in cancer diagnoses as a consequence of the pandemic. Some indirect data suggest that the pandemic has worsened the stage at which some non-hematological neoplasms are diagnosed. Despite the lack of robust evidence, oncology patients seem more likely to have a poor outcome when they contract COVID-19. The antibody response to infection in cancer patients will be fundamentally conditioned by the type of neoplasia present, the treatment received and the time of its administration. In patients with hematological malignancies, the incidence of infection is probably similar or lower than in the general population, due to the better protective measures adopted by the patients and their environment. The severity and mortality of COVID-19 in patients with hematologic malignancies is clearly higher than the general population. Since the immune response to vaccination in hematologic patients is generally worse than in comparable populations, alternative methods of prevention must be established in these patients, as well as actions for earlier diagnosis and treatment. Campaigns for the early diagnosis of malignant neoplasms must be urgently resumed, post-COVID manifestations should be monitored, collaboration with patient associations is indisputable and it is urgent to draw the right conclusions to improve our preparedness to fight against possible future catastrophes.

3.
Revista Ciencias de la Salud ; 20(2), 2022.
Article in Spanish | CAB Abstracts | ID: covidwho-2080962

ABSTRACT

Introduction: We are currently experiencing an extremely complex situation worldwide, due to the covid-19 pandemic caused by the SARS-CoV-2 virus, and the use of social marketing in health management has been indispensable as a tool, since it enables changes in the behavior and conduct of individuals or groups in a political, social and economic environment. Development: Marketing in its social approach is a discipline that has multiple applications in health activities, however, through health promotion it acts as a transversal component and is a tool to prevent, promote and improve the quality of life of individuals through social action. During the covid-19 pandemic it has been necessary to implement strategies for behavioral change in users, as well as in health institutions and its evaluation has achieved a positive positioning of ideas and practices among the population. Conclusions: the use of social marketing during this pandemic has been a powerful tool that has helped to control the pandemic through prevention and control, and it is essential that all health professions have the knowledge of social marketing to solve current problems that every day faces public health worldwide.

4.
American Journal of Transplantation ; 22(Supplement 3):1069, 2022.
Article in English | EMBASE | ID: covidwho-2063450

ABSTRACT

Purpose: Increasing mismatch between kidneys available for transplant and the number of patients on the transplant wait list has led to research into novel sources of organs. One such source is kidneys from hepatitis C NAT positive deceased donors. This was previously deemed unforbidden territory due to the risk of disease transmission;however, with the development of direct-acting antiviral agents for effective treatment of Hepatitis C, this organ pool is now usable. Method(s): A retrospective analysis of outcomes of Hepatitis C NAT positive kidney transplants into Hepatitis C seronegative recipients was conducted at newly opened Appalachian transplant center. Due to insurance constraints, the criteria to initiate hepatitis C therapy was seroconversion to positive Hepatitis C PCR. Outcomes examined include median creatinine, glomerular filtration rate (GFR), liver function tests, recipient Hepatitis C seroconversion, concomitant Ebstein Barr virus (EBV), Cytomegalovirus (CMV) or polyoma hominis (BK) activation, morbidities and mortality. Result(s): Six transplants (of 15 total kidney transplants) from Hepatitis C NAT positive donors were performed in the first year of establishment. Male to female ratio was 2:1 and median patient age was 55.7 years (Range 42-73 years). Median follow-up was 10 months (Range 2-12 months). Diabetes and hypertensive nephrosclerosis were the most common causes of end stage renal disease at 40%. The average time on dialysis was 2.9 years (Range 1-6 years), the most common type being hemodialysis (67%) followed by peritoneal dialysis (33%). Average time on transplant waitlist was 5.57 months (Range 1.2-13.2 months). All patients seroconverted but with treatment, by 24 weeks all patients maintained undetectable viral loads. Patient survival rate was 83% with a death censored graft survival rate of 100%. One patient died due to respiratory failure from COVID-19 infection. Median creatinine and GFr were 1.96 mg/dL (Range 1.8 - 2.6 mg/dL) and 41.3 (Range 35.3 - 50) respectively. One case each of acute antibody and T cell mediated rejection was seen (6.7%), which were treated successfully. CMV, BK and EBV virus reactivation were seen in one patient each (6.7%). The most common complication was COVID-19 infection (50%) followed by neutropenia (33%). Conclusion(s): With the development of direct-acting antiviral agents offering complete cure of Hepatitis C, kidneys from Hepatitis C positive donors can be used for transplantation with excellent outcomes.

5.
American Journal of Transplantation ; 22(Supplement 3):1110, 2022.
Article in English | EMBASE | ID: covidwho-2063405

ABSTRACT

Purpose: Kidney transplantation has become the optimal treatment for end stage renal disease (ESRD), allowing dialysis free survival. Despite widespread availability of transplant programs;rural patients have limited access to transplantation due to several barriers including increased travel time and financial burden. We report outcomes after establishment of a kidney transplant program serving rural West Virginia. Method(s): A retrospective review of the first 15 kidney transplants performed at a newly established Appalachian transplant program was conducted. Primary outcomes measured were graft survival and function. Other outcomes included graft rejection, patient survival and complications. Data related to patient demographics, etiology of ESRD, type of renal replacement therapy, time on transplant waitlist and average travel to transplant center were also collected. Result(s): The first 15 kidneys transplanted had an overall death censored graft survival rate of 100%. Median patient age was 53 (Range 31- 73 years) and a median follow-up of 6 months (Range 1-13 months). The average time on dialysis for this cohort was 4 years (n=13, Range 1-6 years) and average time on waitlist was 4.06 months (Range 0.4-13.2 months). The most common type of dialysis was hemodialysis (77%) followed by peritoneal dialysis (15%). Two patients were predialysis. Diabetes with hypertension (20%), IgA nephropathy (13%) and diabetes without hypertension (13%) were the most common causes of ESRD. Median graft creatinine was 1.51 mg/dL (Range 1.26 - 1.83 mg/dL) with a glomerular filtration rate (GFR) at 51.38 (Range 41.86-70) at one year. One patient developed acute antibody mediated rejection and one developed borderline T cell mediated rejection (13.3%), which were successfully treated with steroids, plasmapheresis and immune globulin therapy. Two patients died (13.3 %);one from acute respiratory failure following coronavirus (COVID-19) infection and one from cardiac arrest secondary to myocarditis (possible COVID-19). Patients experienced COVID-19 infection at a rate of 13.3 %. The average distance patients had to travel was 94 miles (Range 12 - 164 miles) with a travel time of 1 hour and 52 minutes on average (Range 20 minutes - 2.5 hours) to reach the transplant center. Conclusion(s): We report comparable outcomes from our new rural transplant program despite several barriers to delivery of quality care to our population.

6.
American Journal of Lifestyle Medicine ; 16(3):399-407, 2022.
Article in English | CAB Abstracts | ID: covidwho-2053610

ABSTRACT

The study tested the effects of a vegan diet on cardiometabolic outcomes and quality of life among healthcare employees during the COVID-19 pandemic. Overweight hospital employees were enrolled and randomly assigned (in a 1:1 ratio) to an intervention group, which was asked to follow a low-fat vegan diet, or a control group, asked to make no diet changes. However, due to COVID-19 disruptions, all participants remained on their usual diets from March to June (12 weeks), creating a de facto control period, and all (n = 12) started the vegan diet with online classes in June, which continued for 12 weeks. Nine participants completed all final assessments. A crossover ANOVA was used for statistical analysis of differences in cardiovascular health during the control period and during the intervention. Despite the ongoing crisis, body weight decreased (treatment effect -5.7 kg [95% CI -9.7 to -1.7];P = .01);fasting plasma glucose decreased (-11.4 mg/dL [95% CI -18.8 to -4.1];P = .007);total and LDL-cholesterol decreased (-30.7 mg/dL [95% CI -53.8 to -7.5];P = .02;and -24.6 mg/dL [-44.8 to -4.3];P = .02, respectively);diastolic blood pressure decreased (-8.5 mm Hg [95% CI -16.3 to -.7];P = .03);and quality of life increased (P = .005) during the intervention period, compared with the control period. A vegan diet improved cardiometabolic outcomes and quality of life in healthcare workers at the height of the COVID-19 pandemic.

7.
Journal of Clinical Oncology ; 40(16), 2022.
Article in English | EMBASE | ID: covidwho-2005653

ABSTRACT

Background: Inflammation and neutrophils play a central role in severe Covid-19 disease. In previous data, we showed that the FLARE score, combining both tumor and Covid-19-induced proinflammatory status (proinflamstatus), predicts early mortality in cancer patients (pts) with Covid-19 infection. We aimed to assess the impact of this score in a larger cohort and characterize the immunophenotype (IF) of circulating neutrophils. Methods: Multicenter retrospective cohort (RC) of pts with cancer and Covid-19 infection across 14 international centers. Circulating inflammatory markers were collected at two timepoints: baseline (-15 to -45d before Covid-19 diagnosis) and Covid-19 diagnosis. Tumor-induced proinflam-status was defined by high dNLR (neutrophils/(leucocytes-neutrophils)> 3) at baseline. Covid-19-induced proinflam-status was defined by +100% increase of dNLR between both timepoints. We built the FLARE score combining both Tumor and Infection-induced inflammation: T+/I+ (poor), if both proinflam-status;T+/I- (T-only), if inflammation only due to tumor;T-/I+ (I-only), if inflammation only due to Covid;T-/I- (favorable), if no proinflam-status. The IF of circulating neutrophils by flow cytometry was determined in a unicenter prospective cohort (PC) of pts with cancer during Covid-19 infection and in healthy volunteers (HV). Primary endpoint was 30-day mortality. Results: 524 pts were enrolled in the RC with a median follow- up of 84d (95%CI 78-90). Median age was 69 (range 35-98), 52% were male and 78% had baseline PS <1.Thoracic cancers were the most common (26%). 70% had active disease, 51% advanced stage and 57% were under systemic therapy. dNLR was high in 25% at baseline vs 55% at Covid-19 diagnosis. The median dNLR increase between both timepoints was +70% (IQR: 0-349%);42% had +100% increase of dNLR. Pts distribution and mortality across FLARE groups is resumed in the Table. Overall mortality rate was 26%. In multivariate analysis, including gender, stage and PS, the FLARE poor group was independently associated with 30-day mortality [OR 5.27;1.37-20.3]. 44 pts were enrolled in the PC. Median circulating neutrophils were higher in pts with cancer (n=10, 56.7% [IQR: 39-78.4%]) vs HV (n=6, 35.8% [IQR: 25.6-21%]), and particularly higher in pts with cancer and severe Covid-19 infection (n=7, 88.6% [IQR: 80.9-94%] (p=0.003). A more comprehensive characterization of the IF of circulating neutrophils, including Lox1/CD62/CD64, will be presented at ASCO. Conclusions: The FLARE score, combining tumor and Covid-19-induced proinflam-status, can identify the population at higher risk for mortality. A better characterization of circulating neutrophils may help improve the prediction of Covid-19 outcomes in pts with cancer. (Table Presented).

8.
Gastroenterology ; 162(7):S-186-S-187, 2022.
Article in English | EMBASE | ID: covidwho-1967255

ABSTRACT

Background: High no-show rates for colonoscopy have been previously associated with poor clinical outcomes, decreased operational efficiency, and diminished utilization of resources. Studies have suggested that addressing barriers like poor health literacy, logistical challenges, and psycho-emotional issues could reduce no-show rates for colonoscopies. Recently, digital navigation tools designed to eliminate such barriers are an emerging trend with promising results leading to better outcomes for patients undergoing colonoscopy. Objective: The goal of this study was to examine the feasibility of an automated, text message-based digital navigation program and determine the impact on no-show rates for patients undergoing colonoscopies. Methods: Rx.Health developed a Digital Navigation Pathway (DNP) that consisted of bowel-prep instructions, appointment reminders, driving instructions, microlearning videos, and educational messaging. Providers at the Gastroenterology (GI) clinic of NYC Health + Hospitals/Lincoln Medical Center prescribed this pathway through RxUniverse, a digital medicine unification platform, to the patients' smartphones. The sample included patients scheduled for colonoscopy between October 2019 to March 2020 (pre-intervention) and October 2020 to March 2021 (post-intervention). Through a year over year analysis, the mean no-show rates and the number of scheduled colonoscopies at the GI clinic were compared between the pre-intervention and post-intervention groups. Furthermore, as a part of the pre/post program implementation analysis, the colonoscopy utilization patterns at the GI clinic were compared. Results: There were 567 colonoscopies scheduled during the pre-intervention period and 381 scheduled colonoscopies in the post-intervention period. The average no-show rate in the pre-intervention group was 27.81 percent compared to 4.46 percent (p<0.00001)* in the post-intervention group, which translated into an 83.9 percent reduction in no-show rates at the GI clinic. Furthermore, this resulted in 23.7 colonoscopies saved per 100 scheduled colonoscopies in the post-intervention group. Conclusion: Patients that were enrolled in the digital navigation program were more likely to show up to their scheduled colonoscopy appointment compared to patients in the preintervention group. Given the pre-/post implementation study design and COVID-19 pandemic that occurred during the intervention period, future cluster randomized controlled trials should be conducted to examine if there is an association between digital navigation programs and no-show rates for patients undergoing colonoscopies. (Figure Presented) Figure 1. Colonoscopy Bowel Preparation Digital Navigation Pathway (Figure Presented) Figure 2. The Effect of DNPs on No-Show Rates during the Pre- and Post-intervention Period (p < 0.00001) *

9.
Neurology ; 98(18 SUPPL), 2022.
Article in English | EMBASE | ID: covidwho-1925439

ABSTRACT

Objective: To evaluate clinical, laboratory, and epidemiological features of acute neuroinflammatory disorders (ANIDs) that followed the 2016 Zika epidemic in Colombia. Background: The outbreak of Zika virus infection in Colombia in 2015-2016, produced an increased incidence of Guillain-Barré Syndrome (GBS) and other ANID cases. The Neuroviruses Emerging in the Americas Study (NEAS) network was established in 2016 as a multicenter-based observatory of ANIDs to investigate the role of emerging pathogens in neuroinflammatory diseases. Design/Methods: NEAS serves as a multi-center study based on 13 hospitals in 7 cities in Colombia which study all newly diagnosed patients who fulfill established criteria for GBS, encephalitis, myelitis, meningoencephalitis, or cranial nerve disorders as part of an observational cohort. We analyzed the clinical and epidemiological features of all cases evaluated between January 2016 and September 2021. Results: An observational cohort of 825 patients with ANIDs were recruited during the study period. 58.8% of cases were male with a median age of 43 (IQR 25-58) years. The most frequent ANIDs were GBS (46.1%) and facial nerve palsy (28.7%). The diagnosis of encephalitis (9.5%), myelitis (6.5%), and optic neuritis (5.9%) were less frequent. Patients with GBS were predominantly male (70.6%) and had a median age of 49 (IQR 32-60) years. Interestingly, there was an increase incidence of GBS in 2019. Conclusions: The outbreak of Zika in Colombia produced a marked increase in the incidence of GBS in 2016. Although cases of GBS and other ANIDs continued to emerge after the incidence of Zika infection decreased in July 2016, the recent SARS-CoV-2 pandemic has not produced any significant increase in the incidence of GBS in Colombia.

10.
Glob Health Promot ; 29(2): 78-87, 2022 06.
Article in English | MEDLINE | ID: covidwho-1902322

ABSTRACT

Studies evaluating the influence of health literacy on patient behavior and outcomes suggest a positive relationship between health literacy and health knowledge, health behaviors, and health status. In Latin American countries, studies assessing health literacy are few, regional, and demonstrate considerable variation, with reported rates of adequate health literacy ranging from 5.0% to 73.3%. In this paper, we examine and explore the state of health literacy and efforts to promote it in Latin America. Key challenges to those efforts include socioeconomic inequality, social/geographic isolation, and cultural-, language-, and policy-related barriers, many of which disproportionately affect indigenous populations and others living in rural areas. Greater use of infographics, videos, and mobile apps may enhance health literacy and patient empowerment, especially when language barriers exist. This paper provides strategies and tools for tailored programming, examples of successful health literacy interventions, and policy recommendations to improve health literacy in Latin America, intending to spur additional discussion and action. Centrally organized collaboration across multiple sectors of society, with community involvement, will enhance health literacy and improve health and well-being across Latin America.


Subject(s)
Health Literacy , Community Participation , Humans , Latin America
11.
Revista Espanola de Salud Publica ; 95(e202110189), 2021.
Article in Spanish | GIM | ID: covidwho-1870992

ABSTRACT

Background: The mobility of workers to other countries in a globalized work world has posed an added risk in the current pandemy of COVID-19 and can carry with it an increased risk of spread and transmission of the disease. The collaboration of the Occupational Health Units of the companies and the Health Authorities has been fundamental in the investigation of COVID-19 outbreaks secondary to international travel of workers on mission. The objective of this study was to describe the process of detection and follow-up of cases in an outbreak of COVID-19 in repatriated workers after a six-month mission in a factory of aircraft components in Poland.

12.
Revista de la Asociacion Espanola de Especialistas en Medicina del Trabajo ; 30(2):239-243, 2021.
Article in Spanish | EMBASE | ID: covidwho-1848487

ABSTRACT

It is described a case of a 30-year-old health worker who presents a clinical state compatible with reinfection by SARS-CoV-2 or with a false positive diagnostic test for active infection. The temporal sequence of tests performed and symptoms presented are described. The first cases of SARS-CoV-2 disease were reported in December 2019 and to date, knowledge of the diagnostic tests is under continuous review.

13.
Ginecologia y Obstetricia de Mexico ; 90(1):8-20, 2022.
Article in Spanish | Scopus | ID: covidwho-1848036

ABSTRACT

OBJECTIVE: To determine the prevalence of postpartum depression during the CO-VID-19 pandemic and the factors associated with infection. MATERIALS AND METHODS: Observational, analytical and cross-sectional study and carried out in patients attended at Hospital Dr. José Eleuterio González from February to May 2021 after 24 to 48 hours of puerperium. The Edinburgh Scale was applied in writing. Positive screening was considered for postpartum depression with a score greater than 10. Two groups were compared: patients with a history of positive COVID-19 test and those without. Patients with chronic degenerative diseases, rheumatic diseases, pregnancy with death or malformations were excluded. RESULTS: A total of 116 patients were studied: 56 positive for COVID-19 and 60 with no history of disease. The prevalence of depression was 15%. A history of COVID-19 added 2 positive points to the Edinburgh Scale, although it did not result in a factor associated with depression. Factors associated with a score greater than 10 were: junior high and high school education, and male sex of the newborn. Newborn sex resulted in similar percentages in both groups. CONCLUSIONS: COVID-19 contingency and history of SARS CoV-2 infection showed no association with depression. Higher schooling and male birth were observed in women with Edinburgh Scale score greater than 10. © 2022 Asociacion Mexicana de Ginecologia y Obstetricia. All rights reserved.

14.
Revista de Filosofia (Venezuela) ; 39(Especial):787-796, 2022.
Article in Spanish | Scopus | ID: covidwho-1841645

ABSTRACT

Educational feedback allows the open expression of opinions, judgments, recommendations, etc., about the teaching process to correct errors and weaknesses;affirm successes and strengths, while allowing the development of better skills in practicing teachers during daily interaction with their students. Therefore, this research is carried out with the aim of demonstrating the influence of feedback in the systematization of successful educational practices that are carried out at a distance due to the COVID-19 pandemic. The sample consisted of 50 students from two different sections (25 for the control group and 25 for the experimental group) of the ninth cycle of the Early Childhood specialty of the Faculty of Initial Education (FEI) of a Public University. For the data collection, an ad hoc educational experience or good practice systematization file was prepared, which evaluates the pedagogical development in four aspects of the practice: objectives, processes, results, and achievements. The results revealed that the more presence the feedback has, the better the results in the elaboration of the systematization of the educational experience. It is concluded, therefore, that remote feedback is a viable strategy to achieve academic purposes that involve developing more complex cognitive activities by university students. © 2022, Universidad del Zulia. All rights reserved.

15.
Computacion Y Sistemas ; 26(1):473-484, 2022.
Article in English | Web of Science | ID: covidwho-1811410

ABSTRACT

The evaluation problem in educational environments has been a constant, even today due to the current contingency generated by the COVID-19 pandemic, education has had to migrate to the virtual environment and the difficulty of evaluation persists. The purpose of this work is present comprehensively the efforts made in the construction of an intelligent system for the customization of evaluation activities implemented in virtual learning environments. The system architecture consists of three modules. In previous works, an architecture of a strategic learning meta-model has been designed that is divided into three layers, the intelligent layer where an ontological model was designed, the infrastructure layer has been designed with a cloud computing solution and the reactive layer that contains the architecture of the regulation model. Each of these layers corresponds to a module of the system. This work presents the results of three stages of experiments and shows a continuous increase in the approval rate trend.

16.
Handbook of Research on Supporting Social and Emotional Development Through Literacy Education ; : 50-72, 2021.
Article in English | Scopus | ID: covidwho-1810527

ABSTRACT

An exploratory and descriptive case study of the experiences of secondary learners at a community-based learning center on the Caribbean coast in Latin America, this study explores how the Casa Morpho Community of Learners (CoL) model met the socio-emotional (SEL) and literacy needs of adolescents within various virtual environments during the quarantine in Costa Rica. Using lesson plans, teachers' reflective notes, and a developed Learners reflective survey, the following questions were addressed: 1) How did Casa Morpho's curriculum support learners in virtual environments, and with their SEL and literacy needs during the COVID-19 pandemic? 2) What practices were used and how do learners perceive those experiences?. © 2021, IGI Global.

17.
Journal of Allergy and Clinical Immunology ; 149(2):AB57-AB57, 2022.
Article in English | Web of Science | ID: covidwho-1798241
18.
Urvio-Revista Latinoamericana De Estudios De Seguridad ; - (32):27-41, 2022.
Article in Spanish | Web of Science | ID: covidwho-1727034

ABSTRACT

Human mobility has become an extremely complex phenomenon in Mexico, especially the undocumented transit of people from Central American countries to the United States, due to changes in patterns, dynamics of flows and the response of the State. The objective of this article is to describe the main state policies of border and migration control in Mexico that have been consolidated in the last ten years. With a highly restrictive component, these policies have been based on securitization, displacing the relevance of human security. A critical analysis of the influences of the national security paradigm over the representation of migration as a threat in the context of the COVID-19 pandemic is presented. It is concluded that the pandemic allowed to justify the state's indifference to people in an irregular situation in the country, but also to continue implementing immigration containment measures.

SELECTION OF CITATIONS
SEARCH DETAIL