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Practice Nursing ; 33(Sup7):S5-S9, 2022.
Article in English | CINAHL | ID: covidwho-1912187


In the last 2 years, rates of influenza have been unseasonably low, as measures to limit the spread of SARS-CoV-2 virus have reduced the spread of many respiratory infections. The removal of domestic restrictions is leading to increased incidence of many respiratory infections and the threat of morbidity and mortality from influenza viruses remains. Practice nurses have a key role to play in ensuring their eligible practice population are protected by promoting high uptake of influenza vaccination.

Euro Surveill ; 27(15)2022 04.
Article in English | MEDLINE | ID: covidwho-1869325


BackgroundHouseholds appear to be the highest risk setting for COVID-19 transmission. Large household transmission studies in the early stages of the pandemic in Asia reported secondary attack rates ranging from 5 to 30%.AimWe aimed to investigate the transmission dynamics of COVID-19 in household and community settings in the UK.MethodsA prospective case-ascertained study design based on the World Health Organization FFX protocol was undertaken in the UK following the detection of the first case in late January 2020. Household contacts of cases were followed using enhanced surveillance forms to establish whether they developed symptoms of COVID-19, became confirmed cases and their outcomes. We estimated household secondary attack rates (SAR), serial intervals and individual and household basic reproduction numbers. The incubation period was estimated using known point source exposures that resulted in secondary cases.ResultsWe included 233 households with two or more people with 472 contacts. The overall household SAR was 37% (95% CI: 31-43%) with a mean serial interval of 4.67 days, an R0 of 1.85 and a household reproduction number of 2.33. SAR were lower in larger households and highest when the primary case was younger than 18 years. We estimated a mean incubation period of around 4.5 days.ConclusionsRates of COVID-19 household transmission were high in the UK for ages above and under 18 years, emphasising the need for preventative measures in this setting. This study highlights the importance of the FFX protocol in providing early insights on transmission dynamics.

COVID-19 , Adolescent , Family Characteristics , Humans , Pandemics , SARS-CoV-2 , United Kingdom/epidemiology
Practice Nursing ; 32:S10-S14, 2021.
Article in English | ProQuest Central | ID: covidwho-1704020


The influenza immunisation season of 2020/21 was very challenging for practice nurses involved in delivering the programme. The main challenge was delivering the programme while coping with the difficulties of ensuring venues and practices were operating safely with the aim of reducing the risk of transmission of the SARS-CoV-2 virus. There has been comprehensive guidance from the Department of Health and Social Care (DHSC), Public Health England (PHE) and the Royal Colleges to support vaccination providers this year. Additionally, the vaccination programme was expanded to include more patients who are at risk of severe disease from influenza and SARS-CoV-2. This expanded programme is likely to continue in 2021/22 and guidance and directives on influenza vaccines for use in the programme are expected soon.

Bull World Health Organ ; 99(3): 178-189, 2021 Mar 01.
Article in English | MEDLINE | ID: covidwho-1256313


OBJECTIVE: To describe the clinical presentation, course of disease and health-care seeking behaviour of the first few hundred cases of coronavirus disease 2019 (COVID-19) in the United Kingdom of Great Britain and Northern Ireland. METHODS: We implemented the World Health Organization's First Few X cases and contacts investigation protocol for COVID-19. Trained public health professionals collected information on 381 virologically confirmed COVID-19 cases from 31 January 2020 to 9 April 2020. We actively followed up cases to identify exposure to infection, symptoms and outcomes. We also collected limited data on 752 symptomatic people testing negative for COVID-19, as a control group for analyses of the sensitivity, specificity and predictive value of symptoms. FINDINGS: Approximately half of the COVID-19 cases were imported (196 cases; 51.4%), of whom the majority had recent travel to Italy (140 cases; 71.4%). Of the 94 (24.7%) secondary cases, almost all reported close contact with a confirmed case (93 cases; 98.9%), many through household contact (37 cases; 39.8%). By age, a lower proportion of children had COVID-19. Most cases presented with cough, fever and fatigue. The sensitivity and specificity of symptoms varied by age, with nonlinear relationships with age. Although the proportion of COVID-19 cases with fever increased with age, for those with other respiratory infections the occurrence of fever decreased with age. The occurrence of shortness of breath also increased with age in a greater proportion of COVID-19 cases. CONCLUSION: The study has provided useful evidence for generating case definitions and has informed modelling studies of the likely burden of COVID-19.

COVID-19/epidemiology , COVID-19/physiopathology , Adolescent , Adult , Age Distribution , Aged , Child , Child, Preschool , Dyspnea/epidemiology , Female , Humans , Infant , Male , Middle Aged , Respiratory Tract Infections/epidemiology , SARS-CoV-2 , Travel , United Kingdom/epidemiology , Young Adult