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1.
European Journal of Public Health ; 31, 2021.
Article in English | ProQuest Central | ID: covidwho-1515083

ABSTRACT

Introduction Physical activity (PA) is a modifiable lifestyle factor which contributes to improve pregnancy and perinatal outcomes. Therefore, pregnant women (PW) without contraindications should practice 150 minutes of moderate PA per week, according to the World Health Organization (WHO) guidelines. Nevertheless, a reduction of PA throughout the gestational period appears to be worryingly common. The aim of this survey was to analyse the feasibility of the WHO recommendations, investigating PW and midwives' perceptions towards PA during pregnancy, in a view to enhance future PA interventions. Methods A total number of 4 focus groups, involving 10 midwives (aged 43-61) and 10 PW (aged 30-46), recruited at the University Hospital of Bologna, were carried out between July 2020 and April 2021. Due to SARS-CoV-2 restrictions, all meetings were held online, recorded, transcribed and then analysed using the COM-B model. Results WHO recommendations were deemed feasible by both midwives and PW when time management skills and capabilities to adapt PA to individual needs were present. Clearly, women with a background in PA practice tend to be highly motivated thereby maintaining the PA routine also during pregnancy. Both groups reported that PA represents a positive element for the mother's and baby's well-being, triggering a virtuous circle and increasing motivation. Being able to access and perform simple, structured, evidence-based activities, family support, and using every opportunity to be less sedentary were reported as key aspects amongst opportunities to improve PA levels. Conclusions Positive perception regarding feasibility of the recommendations was similar between groups;nevertheless, midwives perceived pregnancy as an opportunity to change PA routines, while PW considered pregnancy a less dynamic period. Therefore, implementing PA promotion involving midwives might represent a good strategy given their central role during this woman' unique period. Key messages WHO physical activity recommendations are overall deemed feasible, but tailored opportunities and strategies tackling everyday obstacles and lack of information need to be provided. Enhancing PA is a key challenge for pregnant women in a view of their own and baby's health. The COM-B model can be used to implement new strategies involving midwives to reach the goal.

2.
European Journal of Public Health ; 31, 2021.
Article in English | ProQuest Central | ID: covidwho-1514607

ABSTRACT

Background The COVID-19 outbreak has forcibly overshadowed the physical well-being of children and adolescents, of which we will see the consequences in near future. The programs to contain the spread of Sars-CoV-2 resulted in prolonged lockdown periods, discontinuity of educational services and a possible decrease in physical activities (PA) among the youngest. In the local reality of the Metropolitan City of Bologna children and adolescents underwent a radical change in habits and lifestyle, overall predisposing sedentariness and unhealthy behaviors. Our project, “Come te la passi?”, aims to acknowledge lifestyle variations (concerning diet, PA, sleep behavior/quality) to design, in second-phase interventions, individualized school-based educational programs. Methods This ongoing study is being conducted using an on-line anonymous questionnaire targeting parents/guardian of children and adolescents aged 6-17 recruited from 26th to 28th of April in Bologna, a city in Northern Italy. Results Preliminary data suggested that among adolescents (n = 124) 91.2% used to do PA 2 or more times a week before lockdown, while during lockdown this percentage decreased, reaching 41.1%. In children (n = 38) we observed an even more pronounced difference, with PA decreasing from 89.5% to 26.3%. In children 29% of the participants also reported a weight gain, while 65.8% did not report any variation and only 5.2% reported a weight loss. For the majority of both children's and adolescents' parents (n = 162), the strategies to address the reduction in PA were predominantly having school time dedicated only to PA (53.1%) and being more educated about simple physical exercises (14.5%). Conclusions Our preliminary findings suggest that the current pandemic had a strong impact on the well-being of children and adolescents;“Come te la passi?” second-phase interventions could be crucial in addressing the youngest' needs, to educate and promote healthier lifestyles through school-based programs. Key messages Children’s and adolescents’ lifestyle behaviors were strongly affected by the current pandemic, with physical activity frequency more than halved. “Come te la passi?” objectives are to frame the major critical issues detected and to shape educational school programs based on identified needs.

3.
In_Bo ; 11(15):16-19+140, 2020.
Article in Italian | Scopus | ID: covidwho-1502737

ABSTRACT

The narrative of the journey has reconfirmed itself as a fundamental tool for narrating spaces, gaining new forms during the global pandemic. In a parallel between cinema, architecture and literature, the essay approaches some forms of travel through five paragraphs, making a scalar journey that from the unknown extraterrestrial magnifies the city and the territory, and then focuses on the domestic space. Between these heterogeneous cases, it emerges a common point, namely the dual nature of real or fictitious, introverted or extroverted, which characterizes the narrative of a contradictory coexistence of opposites. Thus, understood as a recording of a place, the journey could not be just a trajectory that crosses territories, but a non-linear path characterized by flashbacks and fast-forwards. The destination seems often absent or uncertain, resembling the indefinite and unknown situation of the current scenario of the global pandemic of the Covid-19. The state of emergency has suspended and altered the city's narratives, subverting the narrative of urban and domestic space and witnessing a radical mutation of the known relations, scales and dimensions. Surrounded by a collective pandemic narrative, we now live introspective and individual journeys. If the conditions for the fruition of space are now compromised, the desire to travel to new unknown worlds continue, precisely through the narratives, stories of territories that have not been known physically. © In_Bo 2020.

4.
Genetic Epidemiology ; 45(7):785, 2021.
Article in English | EMBASE | ID: covidwho-1458017

ABSTRACT

Molecular data analysis is invaluable in understanding the overall behavior of a rapidly spreading virus population when epidemiological surveillance is problematic. It is also particularly beneficial in describing subgroups within the population, often identified as clades within a phylogenetic tree, that represent individuals connected via direct transmission or transmission via differing risk factors in viral spread. However, transmission patterns or viral dynamics within these smaller groups should not be expected to exhibit homogeneous behavior over time. As such, standard phylogenetic approaches that identify clusters based on summary statistics (e.g., median genetic distance over the clade) would not be expected to capture dynamic clusters of transmission. For this purpose, we have developed DYNAMITE (DYNAMic Identification of Transmission Epicenters), a cluster identification algorithm based on a branchwise (rather than traditional cladewise) search for cluster criteria, allowing partial clades to be recognized as chains of transmission linked individuals. Using simulated viral outbreaks with varying cluster types and dynamics, as well as a SARS-CoV-2 South African dataset including the variant of concern B.1.351, we show that DYNAMITE is consistently more sensitive than existing tools in detecting both static and dynamic transmission clusters of epidemiological relevance. DYNAMITE has been implemented in R and released as open source at: github.com/ProsperiLab/DYNAMITE.

5.
Annals of Oncology ; 32:S1151, 2021.
Article in English | EMBASE | ID: covidwho-1432904

ABSTRACT

Background: By the end of 2020, coronavirus disease 2019 (COVID-19) would have indelibly marked the cancer care setting. With Italy at the forefront of pandemic, unprecedented measures were adopted to tackle the quality care issue. As a result of pausing screening programs, diagnostic delays might affect the years to come. Aim of our multicenter Italian study is to evaluate whether the COVID-19 outbreak has impacted on likelihood of receiving timely diagnosis, staging and treatment for colorectal cancer (CRC) patients (pts) after March 2020 compared to pre-pandemic time. Methods: Medical records of all consecutive newly diagnosed CRC pts referred to 4 Italian Oncology Departments between March and December 2020 were examined. Access rate (number of pts/days) and temporal intervals between date of symptoms onset, radiological and cytohistological diagnosis, treatment start and first radiological evaluation were analyzed and compared with the same months of 2019. Differences between the two years were evaluated using Fisher’s exact test or chi-square test for categorical variables and unpaired Student t test, or the Mann-Whitney U test for continuous variables. Results: A reduction (20%) in newly diagnosed CRC cases was seen when compared with 2019 (214 vs 268). The decline was greater in the lockdown period compared to the other months (percentage drop 40 % vs 12%). Newly CRC pts in 2020 were less likely to be diagnosed with early stage (stage I-II-III) CRC (67% vs 72%). Other clinical and tumor characteristics were similar regardless of the year. Looking at pts management, no differences emerged in terms of interval between symptom onset and radiological diagnosis (median 19 days in 2020 vs 28 days in 2019, p = 0.88), symptom onset and cytohistological diagnosis (25 vs 36 days, p = 0.27), symptom onset and treatment start (median 86 vs 100 days, p = 0.79). However, less CRC were discussed in multidisciplinary tumor meetings during the 2020 (45% vs 54%, p = 0.07). Conclusions: While COVID-19 repercussions will be likely felt for decades to come, our data suggest an alarming drop in early-stage CRC diagnoses during the first pandemic year. Conversely, our study draws the attention on the efforts made to ensure diagnostic-therapeutic pathways proper operation. Legal entity responsible for the study: The authors. Funding: Has not received any funding. Disclosure: All authors have declared no conflicts of interest.

6.
European Psychiatry ; 64(S1):S297, 2021.
Article in English | ProQuest Central | ID: covidwho-1357243

ABSTRACT

IntroductionAffective flattening is one of the main symptoms in Schizophrenia, several studies highlighted the importance of social skills training in improving negative symptoms. However, Covid-19 pandemic is changing our life with limitations in social contacts and in psychosocial rehabilitation;pre COVID-19 strategies should be implemented with new ones.ObjectivesTo evaluate the practicability of a narrative method in improving affective flattening, general social skills in stable outpatients with a diagnosis for schizophrenia during Italian lockdown in March – April 2020MethodsOutpatients with a stable psychopathology have been involved in a narrative project during lockdown. We asked to patients to write daily a story telling about their experience and emotions and send us their diary. Every week the diary has been used to discuss their story telling in group in a web conference. At end of the experience we administered a survey about the enjoyment and the subjective benefits.ResultsFrom ten people with a known psychopathology we recruited six patients. All participants completed the project and all of them referred for a subjective benefit as to feel more reassured by the contact with their psychiatrist. Four patients explicated initial discomfort about share their experiences in group. One patient started to share his own thoughts about mental disease on social media.ConclusionsNarrative Psychiatry might be a pragmatic opportunity to implement conventional strategies to contrast affective flattening and negative symptoms in Schizophrenia. Sharing digital story telling is a useful method in lockdown and general social restriction condition.

7.
J Biol Regul Homeost Agents ; 34(3): 757-766, 2020.
Article in English | MEDLINE | ID: covidwho-401296

ABSTRACT

The aim of the multicentre study promoted by Nuova FIO is to evaluate the beneficial effects of the systemic Oxygen-Ozone (O2O3) therapy in patients suffering from SARS COV-2 disease in the early phases of the disease, before worsening, up to the need of tracheal intubation. The study is based on the rationale on that the systemic oxygen-ozone treatment could be effective, positively influencing the disease evolution and/or being able to mitigate the onset of the cytokine storm syndrome at least partially.


Subject(s)
Coronavirus Infections/therapy , Oxygen/therapeutic use , Ozone/therapeutic use , Pneumonia, Viral/therapy , Betacoronavirus , COVID-19 , Humans , Pandemics , SARS-CoV-2
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