Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
1.
Biomolecules ; 11(1)2020 12 24.
Article in English | MEDLINE | ID: covidwho-1067683

ABSTRACT

The medical burden caused by respiratory manifestations of influenza virus (IV) outbreak as an infectious respiratory disease is so great that governments in both developed and developing countries have allocated significant national budget toward the development of strategies for prevention, control, and treatment of this infection, which is seemingly common and treatable, but can be deadly. Frequent mutations in its genome structure often result in resistance to standard medications. Thus, new generations of treatments are critical to combat this ever-evolving infection. Plant materials and active compounds have been tested for many years, including, more recently, active compounds like flavonoids. Quercetin is a compound belonging to the flavonols class and has shown therapeutic effects against influenza virus. The focus of this review includes viral pathogenesis as well as the application of quercetin and its derivatives as a complementary therapy in controlling influenza and its related symptoms based on the targets. We also touch on the potential of this class of compounds for treatment of SARS-COV-2, the cause of new pandemic.


Subject(s)
COVID-19 , Disease Outbreaks , Influenza A virus/metabolism , Influenza, Human , Quercetin/therapeutic use , SARS-CoV-2/metabolism , COVID-19/drug therapy , COVID-19/epidemiology , COVID-19/metabolism , Humans , Influenza, Human/drug therapy , Influenza, Human/epidemiology , Influenza, Human/metabolism
2.
Biomolecules ; 11(1):10, 2021.
Article in English | ScienceDirect | ID: covidwho-984585

ABSTRACT

The medical burden caused by respiratory manifestations of influenza virus (IV) outbreak as an infectious respiratory disease is so great that governments in both developed and developing countries have allocated significant national budget toward the development of strategies for prevention, control, and treatment of this infection, which is seemingly common and treatable, but can be deadly. Frequent mutations in its genome structure often result in resistance to standard medications. Thus, new generations of treatments are critical to combat this ever-evolving infection. Plant materials and active compounds have been tested for many years, including, more recently, active compounds like flavonoids. Quercetin is a compound belonging to the flavonols class and has shown therapeutic effects against influenza virus. The focus of this review includes viral pathogenesis as well as the application of quercetin and its derivatives as a complementary therapy in controlling influenza and its related symptoms based on the targets. We also touch on the potential of this class of compounds for treatment of SARS-COV-2, the cause of new pandemic.

3.
Otolaryngol Pol ; 74(3): 1-5, 2020 Jun 30.
Article in English | MEDLINE | ID: covidwho-252801

ABSTRACT

Recommendations of the Main Board of the Polish Society of Otorhinolaryngologists, Head and Neck Surgeons for providing services during the COVID-19 pandemic constitute the guidance to outpatient and hospital practices in all cases where contact with a patient whose status of COVID-19 is unknown. They have been created based on world publications and recommendations due to the current state of the COVID-19 pandemic. Justification for suspension of planned provision of services in the first phase of a pandemic was presented. The indication of the best medical practices for the time of stabilization, but with the persistence of the risk of COVID-19 infection in the population are discussed. The possibility of providing services in the following months of the pandemic is important. We provide the rationale for launching medical activities and indicate optimal practices until the consolidation of SARS COV-2 prevention and treatment methods.


Subject(s)
Anesthesiology/standards , Coronavirus Infections , Disease Transmission, Infectious/prevention & control , Infection Control/standards , Otolaryngology/standards , Pandemics , Patient Care/standards , Pneumonia, Viral , Ambulatory Care/standards , COVID-19 , Coronavirus Infections/diagnosis , Coronavirus Infections/prevention & control , Coronavirus Infections/transmission , Hospitalization , Humans , Otorhinolaryngologic Diseases/therapy , Otorhinolaryngologic Surgical Procedures/standards , Pandemics/prevention & control , Personal Protective Equipment/standards , Pneumonia, Viral/diagnosis , Pneumonia, Viral/prevention & control , Pneumonia, Viral/transmission , Poland
SELECTION OF CITATIONS
SEARCH DETAIL