Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 22
Filter
1.
Enfermedades infecciosas y microbiologia clinica (English ed.) ; 2022.
Article in English | EuropePMC | ID: covidwho-1863858

ABSTRACT

Introduction In the present manuscript we describe the planning carried out in our hospital to adapt our diagnostic capability to perform large numbers of SARS-CoV-2 RT-PCR. Methods The analysis and prediction of workflow included the number of RT-PCR per week from the beginning of the pandemic, with a total of 31971 determinations. The planning phase was developed based on the different scenarios previously predicted. Results According to the predictions obtained, an automated custom solution was chosen, based on the use of the OT-2 open-source liquid-handling robots (Opentrons), to design a reproducible workflow that achieved a production capacity of 5640 samples/day, with a time of response of four hours per procedure. Conclusions The analysis and prediction of workflow, along with the use of the robotic platforms OT-2, provided a robust structure to deal with the high demand of determinations that this pandemic requires.

2.
EuropePMC; 2022.
Preprint in English | EuropePMC | ID: ppcovidwho-336818

ABSTRACT

Although the utility of Ecological Niche models (ENM) and Species Distribution models (SDM) has been demonstrated in many ecological applications, their suitability for modelling epidemics or pandemics, such as SARS-Cov-2, has been questioned. In this paper, contrary to this viewpoint, we show that ENMs and SDMs can be created that can describe the evolution of pandemics, both in space and time. As an illustrative use case, we create models for predicting confirmed cases of COVID-19, viewed as our target “species”, in Mexico through 2020 and 2021, showing that the models are predictive in both space and time. In order to achieve this, we extend a recently developed Bayesian framework for niche modelling, to include: i) dynamic, non-equilibrium “species” distributions;ii) a wider set of habitat variables, including behavioural, socio-economic and socio-demographic variables, as well as standard climatic variables;iii) distinct models and associated niches for different species characteristics, showing how the niche, as deduced through presence-absence data, can differ from that deduced from abundance data. We show that the niche associated with those places with the highest abundance of cases has been highly conserved throughout the pandemic, while the inferred niche associated with presence of cases has been changing. Finally, we show how causal chains can be inferred and confounding identified by showing that behavioural and social factors are much more predictive than climate and that, further, the latter is confounded by the former.

3.
Enferm Infecc Microbiol Clin (Engl Ed) ; 2022 May 13.
Article in English | MEDLINE | ID: covidwho-1850984

ABSTRACT

INTRODUCTION: In the present manuscript we describe the planning carried out in our hospital to adapt our diagnostic capability to perform large numbers of SARS-CoV-2 RT-PCR. METHODS: The analysis and prediction of workflow included the number of RT-PCR per week from the beginning of the pandemic, with a total of 31971 determinations. The planning phase was developed based on the different scenarios previously predicted. RESULTS: According to the predictions obtained, an automated custom solution was chosen, based on the use of the OT-2 open-source liquid-handling robots (Opentrons), to design a reproducible workflow that achieved a production capacity of 5640 samples/day, with a time of response of four hours per procedure. CONCLUSIONS: The analysis and prediction of workflow, along with the use of the robotic platforms OT-2, provided a robust structure to deal with the high demand of determinations that this pandemic requires.

4.
Sci Rep ; 12(1): 7397, 2022 05 05.
Article in English | MEDLINE | ID: covidwho-1821620

ABSTRACT

The main objective was to evaluate the viability of the SARS-CoV-2 viral particles excreted in stools. In addition, we aimed to identify clinical factors associated with the detection of SARS-CoV-2 RNA in feces, and to determine if its presence is associated with an unfavorable clinical outcome, defined as intensive care unit (ICU) admission and/or death. A prospective multicenter cohort study of COVID-19 adult patients, with confirmed SARS-CoV-2 infection by RT-PCR assay in nasopharyngeal (NP) swabs admitted to four hospitals in Spain, from March 2020 to February 2021. Sixty-two adult COVID-19 patients had stool samples collected at admission and/or during the follow up, with a total of 79 stool samples. SARS-CoV-2 RNA was detected in stool samples from 27 (43.5%) out of the 62 patients. Replicative virus, measured by the generation of cytopathic effect in cell culture and subsequent RT-PCR confirmation of a decrease in the Ct values, was not found in any of these stool samples. Fecal virus excretion was not associated with the presence of gastrointestinal symptoms, or with differences in the evolution of COVID-19 patients. Our results suggest that SARS-CoV-2 replicative capacity is null or very limited in stool samples, and thus, the fecal-oral transmission of SARS-CoV-2 as an alternative infection route is highly unlikely. In our study, the detection of SARS-CoV-2 RNA in feces at the beginning of the disease is not associated with any clinical factor nor with an unfavorable clinical outcome.


Subject(s)
COVID-19 , SARS-CoV-2 , Adult , COVID-19/diagnosis , Cohort Studies , Feces , Humans , Prospective Studies , RNA, Viral/genetics , SARS-CoV-2/genetics
5.
EuropePMC; 2020.
Preprint in English | EuropePMC | ID: ppcovidwho-320728

ABSTRACT

Background: Possible COVID-19 pneumonia (ppCOVID-19) patients generally overwhelmed EDs during the first COVID-19 wave. Home-confinement and primary care phone follow-ups was the first-level regional policy for preventing EDs to collapse. But when ppCOVID-19 needed x-rays assessment, the traditional outpatient workflow at the radiology department (RD) was inefficient and raised concerns about potential interpersonal infections. We aimed to assess the efficiency of a primary care high-resolution radiology service (pcHRRS) for ppCOVID-19 in terms of time consumed at hospital and decision’s reliability. Methods: We assessed 849 consecutive ppCOVID-19 patients, 418 appointed by general practitioners to the pcHRRS (home-confined ppCOVID-19 cases with negative –group-1- and positive -group-2- x-ray results) and 431 arriving the ED by themselves (group-3). The pcHRRS provided x-rays and oximetry in an only-one-patient agenda for home-confined ppCOVID-19 patients. Radiologists made next-step decisions (group-1: pneumonia-, home-confinement follow-up;group-2: pneumonia+, ED assessment) according to x-rays results. ANOVA and Bonferroni correction, t-student, Kruskal-Wallis, and Chi2 tests were used to analyse changes in the ED workload, time-to-decision differences between groups, and pcHRRS performance for discriminating need for admission. Results: The pcHRRS halved ED respiratory patients (49.2%), allowed faster decisions (group-1 vs. home-discharged group-2 and group-3 patients: 0:41±1:05h vs. 3:50±3:16h;group-1 vs. all group-2 and group-3 patients: 0:41±1:05h vs. 5:36±4:36h;group-2 vs. group-3 admitted patients: 5:27±3:08h vs. 7:42±5:02h;P <0.001) and prompted admission in most cases (84/93, 90.3%). Conclusions: A Radiology Department pcHRRS may be a more efficient entry-door for ppCOVID-19 by decreasing ED patients and making expedited decisions while guaranteeing social distance.

6.
Gigascience ; 10(12)2021 12 02.
Article in English | MEDLINE | ID: covidwho-1550549

ABSTRACT

BACKGROUND: The current SARS-CoV-2 pandemic has emphasized the utility of viral whole-genome sequencing in the surveillance and control of the pathogen. An unprecedented ongoing global initiative is producing hundreds of thousands of sequences worldwide. However, the complex circumstances in which viruses are sequenced, along with the demand of urgent results, causes a high rate of incomplete and, therefore, useless sequences. Viral sequences evolve in the context of a complex phylogeny and different positions along the genome are in linkage disequilibrium. Therefore, an imputation method would be able to predict missing positions from the available sequencing data. RESULTS: We have developed the impuSARS application, which takes advantage of the enormous number of SARS-CoV-2 genomes available, using a reference panel containing 239,301 sequences, to produce missing data imputation in viral genomes. ImpuSARS was tested in a wide range of conditions (continuous fragments, amplicons or sparse individual positions missing), showing great fidelity when reconstructing the original sequences, recovering the lineage with a 100% precision for almost all the lineages, even in very poorly covered genomes (<20%). CONCLUSIONS: Imputation can improve the pace of SARS-CoV-2 sequencing production by recovering many incomplete or low-quality sequences that would be otherwise discarded. ImpuSARS can be incorporated in any primary data processing pipeline for SARS-CoV-2 whole-genome sequencing.


Subject(s)
Genome, Viral , SARS-CoV-2 , Phylogeny , SARS-CoV-2/genetics , Whole Genome Sequencing
7.
Front Public Health ; 9: 737755, 2021.
Article in English | MEDLINE | ID: covidwho-1497179

ABSTRACT

Objectives: Each new wave of the COVID-19 pandemic invites the possible obligation to prioritize individuals' access to vital resources, and thereby leads to unresolved and important bioethical concerns. Governments have to make decisions to protect access to the health system with equity. The prioritization criteria during a pandemic are both a clinical and legal-administrative decision with ethical repercussion. We aim to analyse the prioritization protocols used in Spain during the pandemic which, in many cases, have not been updated. Method: We carried out a narrative review of 27 protocols of prioritization proposed by healthcare ethics committees, scientific societies and institutions in Spain for this study. The review evaluated shared aspects and unique differences and proffered a bioethical reflection. Results: The research questions explored patient prioritization, the criteria applied and the relative weight assigned to each criterion. There was a need to use several indicators, being morbidity and mortality scales the most commonly used, followed by facets pertaining to disease severity and functional status. Although age was initially considered in some protocols, it cannot be the sole criterion used when assigning care resources. Conclusions: In COVID-19 pandemic there is a need for a unified set of criteria that guarantees equity and transparency in decision-making processes. Establishing treatment indications is not the aim of such criteria, but instead prioritizing access to care resources. In protocols of prioritization, the principle of efficiency must vary according to the principle of equity and the criteria used to guarantee such equity.


Subject(s)
COVID-19 , Pandemics , Delivery of Health Care , Ethics Committees , Humans , Pandemics/prevention & control , SARS-CoV-2 , Spain/epidemiology
8.
J Virol ; 96(2): e0106321, 2022 01 26.
Article in English | MEDLINE | ID: covidwho-1476388

ABSTRACT

COVID-19 affects multiple organs. Clinical data from the Mount Sinai Health System show that substantial numbers of COVID-19 patients without prior heart disease develop cardiac dysfunction. How COVID-19 patients develop cardiac disease is not known. We integrated cell biological and physiological analyses of human cardiomyocytes differentiated from human induced pluripotent stem cells (hiPSCs) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the presence of interleukins (ILs) with clinical findings related to laboratory values in COVID-19 patients to identify plausible mechanisms of cardiac disease in COVID-19 patients. We infected hiPSC-derived cardiomyocytes from healthy human subjects with SARS-CoV-2 in the absence and presence of IL-6 and IL-1ß. Infection resulted in increased numbers of multinucleated cells. Interleukin treatment and infection resulted in disorganization of myofibrils, extracellular release of troponin I, and reduced and erratic beating. Infection resulted in decreased expression of mRNA encoding key proteins of the cardiomyocyte contractile apparatus. Although interleukins did not increase the extent of infection, they increased the contractile dysfunction associated with viral infection of cardiomyocytes, resulting in cessation of beating. Clinical data from hospitalized patients from the Mount Sinai Health System show that a significant portion of COVID-19 patients without history of heart disease have elevated troponin and interleukin levels. A substantial subset of these patients showed reduced left ventricular function by echocardiography. Our laboratory observations, combined with the clinical data, indicate that direct effects on cardiomyocytes by interleukins and SARS-CoV-2 infection might underlie heart disease in COVID-19 patients. IMPORTANCE SARS-CoV-2 infects multiple organs, including the heart. Analyses of hospitalized patients show that a substantial number without prior indication of heart disease or comorbidities show significant injury to heart tissue, assessed by increased levels of troponin in blood. We studied the cell biological and physiological effects of virus infection of healthy human iPSC-derived cardiomyocytes in culture. Virus infection with interleukins disorganizes myofibrils, increases cell size and the numbers of multinucleated cells, and suppresses the expression of proteins of the contractile apparatus. Viral infection of cardiomyocytes in culture triggers release of troponin similar to elevation in levels of COVID-19 patients with heart disease. Viral infection in the presence of interleukins slows down and desynchronizes the beating of cardiomyocytes in culture. The cell-level physiological changes are similar to decreases in left ventricular ejection seen in imaging of patients' hearts. These observations suggest that direct injury to heart tissue by virus can be one underlying cause of heart disease in COVID-19.


Subject(s)
COVID-19/immunology , Induced Pluripotent Stem Cells , Interleukin-10/immunology , Interleukin-1beta/immunology , Interleukin-6/immunology , Myocytes, Cardiac , Cells, Cultured , Humans , Induced Pluripotent Stem Cells/immunology , Induced Pluripotent Stem Cells/pathology , Induced Pluripotent Stem Cells/virology , Myocytes, Cardiac/immunology , Myocytes, Cardiac/pathology , Myocytes, Cardiac/virology
10.
Enferm Infecc Microbiol Clin (Engl Ed) ; 2021 Feb 11.
Article in English, Spanish | MEDLINE | ID: covidwho-1385467

ABSTRACT

INTRODUCTION: In the present manuscript we describe the planning carried out in our hospital to adapt our diagnostic capability to perform large numbers of SARS-CoV-2 RT-PCR. METHODS: The analysis and prediction of workflow included the number of RT-PCR per week from the beginning of the pandemic, with a total of 31971 determinations. The planning phase was developed based on the different scenarios previously predicted. RESULTS: According to the predictions obtained, an automated custom solution was chosen, based on the use of the OT-2 open-source liquid-handling robots (Opentrons), to design a reproducible workflow that achieved a production capacity of 5640 samples/day, with a time of response of four hours per procedure. CONCLUSIONS: The analysis and prediction of workflow, along with the use of the robotic platforms OT-2, provided a robust structure to deal with the high demand of determinations that this pandemic requires.

11.
Humanities & Social Sciences Communications ; 8(1), 2021.
Article in English | ProQuest Central | ID: covidwho-1319064

ABSTRACT

This study investigates the effects of the flipped classroom on Education students’ perceptions of their learning and motivation during the current pandemic. The sample consisted of 179 student teachers from the Faculty of Education of the University of Murcia in the academic year 2020–2021, in which the flipped classroom model was implemented. Identical surveys were administered and examined through both descriptive statistics and non-parametric tests. Statistically significant differences were found between pre-tests and post-tests with experienced students scoring higher on average in the latter. Most students had a positive perception about the flipped classroom, noting the advantage of practical in-class activities, as well as increased self-autonomy in learning.

12.
Sci Rep ; 11(1): 12931, 2021 06 21.
Article in English | MEDLINE | ID: covidwho-1279900

ABSTRACT

The aim was to assess the ability of nasopharyngeal SARS-CoV-2 viral load at first patient's hospital evaluation to predict unfavorable outcomes. We conducted a prospective cohort study including 321 adult patients with confirmed COVID-19 through RT-PCR in nasopharyngeal swabs. Quantitative Synthetic SARS-CoV-2 RNA cycle threshold values were used to calculate the viral load in log10 copies/mL. Disease severity at the end of follow up was categorized into mild, moderate, and severe. Primary endpoint was a composite of intensive care unit (ICU) admission and/or death (n = 85, 26.4%). Univariable and multivariable logistic regression analyses were performed. Nasopharyngeal SARS-CoV-2 viral load over the second quartile (≥ 7.35 log10 copies/mL, p = 0.003) and second tertile (≥ 8.27 log10 copies/mL, p = 0.01) were associated to unfavorable outcome in the unadjusted logistic regression analysis. However, in the final multivariable analysis, viral load was not independently associated with an unfavorable outcome. Five predictors were independently associated with increased odds of ICU admission and/or death: age ≥ 70 years, SpO2, neutrophils > 7.5 × 103/µL, lactate dehydrogenase ≥ 300 U/L, and C-reactive protein ≥ 100 mg/L. In summary, nasopharyngeal SARS-CoV-2 viral load on admission is generally high in patients with COVID-19, regardless of illness severity, but it cannot be used as an independent predictor of unfavorable clinical outcome.


Subject(s)
COVID-19 Nucleic Acid Testing , COVID-19/diagnosis , Nasopharynx/virology , SARS-CoV-2/genetics , Severity of Illness Index , Viral Load/methods , Adult , Aged , Aged, 80 and over , COVID-19/virology , Female , Follow-Up Studies , Humans , Intensive Care Units , Male , Middle Aged , Patient Admission , Prognosis , Prospective Studies , RNA, Viral/genetics , Real-Time Polymerase Chain Reaction , Risk Factors
13.
MMWR Morb Mortal Wkly Rep ; 70(24): 888-894, 2021 Jun 18.
Article in English | MEDLINE | ID: covidwho-1278793

ABSTRACT

Beginning in March 2020, the COVID-19 pandemic and response, which included physical distancing and stay-at-home orders, disrupted daily life in the United States. Compared with the rate in 2019, a 31% increase in the proportion of mental health-related emergency department (ED) visits occurred among adolescents aged 12-17 years in 2020 (1). In June 2020, 25% of surveyed adults aged 18-24 years reported experiencing suicidal ideation related to the pandemic in the past 30 days (2). More recent patterns of ED visits for suspected suicide attempts among these age groups are unclear. Using data from the National Syndromic Surveillance Program (NSSP),* CDC examined trends in ED visits for suspected suicide attempts† during January 1, 2019-May 15, 2021, among persons aged 12-25 years, by sex, and at three distinct phases of the COVID-19 pandemic. Compared with the corresponding period in 2019, persons aged 12-25 years made fewer ED visits for suspected suicide attempts during March 29-April 25, 2020. However, by early May 2020, ED visit counts for suspected suicide attempts began increasing among adolescents aged 12-17 years, especially among girls. During July 26-August 22, 2020, the mean weekly number of ED visits for suspected suicide attempts among girls aged 12-17 years was 26.2% higher than during the same period a year earlier; during February 21-March 20, 2021, mean weekly ED visit counts for suspected suicide attempts were 50.6% higher among girls aged 12-17 years compared with the same period in 2019. Suicide prevention measures focused on young persons call for a comprehensive approach, that is adapted during times of infrastructure disruption, involving multisectoral partnerships (e.g., public health, mental health, schools, and families) and implementation of evidence-based strategies (3) that address the range of factors influencing suicide risk.


Subject(s)
COVID-19/epidemiology , Emergency Service, Hospital/statistics & numerical data , Suicide, Attempted/statistics & numerical data , Adolescent , Adult , Child , Female , Humans , Male , United States/epidemiology , Young Adult
14.
PLoS One ; 16(3): e0249249, 2021.
Article in English | MEDLINE | ID: covidwho-1150559

ABSTRACT

This study aimed to investigate the characteristics related to SARS-CoV-2 in Luanda, Angola. A total of 622 individuals were screened for SARS-CoV-2 from January to September 2020. Chi-square and logistic regression were used to identify the relationship between sociodemographic characteristics and SARS-CoV-2. Of the 622 tested, 14.3% tested positive. The infection rate was the same for both genders (14.3%). Individuals ≥40 years old, from non-urbanized areas, and healthcare professionals had a higher frequency of infection. The risk of infection was very high in individuals ≥60 years old (AOR: 23.3, 95% CI: 4.83-112), in women (AOR: 1.24, 95% CI: 0.76-2.04), in Luanda (AOR: 7.40, 95% CI: 1.64-33.4), and healthcare professionals (AOR: 1.27, 95% CI: 0.60-2.71), whereas a low risk was observed in individuals from urbanized areas (AOR: 0.44, 95% CI: 0.26-0.75). Our results suggest that Angolan authorities should implement a greater effort in non-urbanized areas and among healthcare professionals since when these individuals presented any indication for a COVID-19 test, such as fever/cough/myalgia, they were more likely to test positive for SARS-CoV-2 than having some other cause for symptoms.


Subject(s)
COVID-19/diagnosis , Adolescent , Adult , Aged , Aged, 80 and over , Angola , COVID-19/pathology , COVID-19/virology , COVID-19 Testing , Child , Child, Preschool , Cross-Sectional Studies , Demography , Female , Humans , Infant , Male , Middle Aged , Odds Ratio , Risk Factors , SARS-CoV-2/isolation & purification , Young Adult
15.
JAMA Psychiatry ; 78(4): 372-379, 2021 04 01.
Article in English | MEDLINE | ID: covidwho-1060999

ABSTRACT

Importance: The coronavirus disease 2019 (COVID-19) pandemic, associated mitigation measures, and social and economic impacts may affect mental health, suicidal behavior, substance use, and violence. Objective: To examine changes in US emergency department (ED) visits for mental health conditions (MHCs), suicide attempts (SAs), overdose (OD), and violence outcomes during the COVID-19 pandemic. Design, Setting, and Participants: This cross-sectional study used data from the Centers for Disease Control and Prevention's National Syndromic Surveillance Program to examine national changes in ED visits for MHCs, SAs, ODs, and violence from December 30, 2018, to October 10, 2020 (before and during the COVID-19 pandemic). The National Syndromic Surveillance Program captures approximately 70% of US ED visits from more than 3500 EDs that cover 48 states and Washington, DC. Main Outcomes and Measures: Outcome measures were MHCs, SAs, all drug ODs, opioid ODs, intimate partner violence (IPV), and suspected child abuse and neglect (SCAN) ED visit counts and rates. Weekly ED visit counts and rates were computed overall and stratified by sex. Results: From December 30, 2018, to October 10, 2020, a total of 187 508 065 total ED visits (53.6% female and 46.1% male) were captured; 6 018 318 included at least 1 study outcome (visits not mutually exclusive). Total ED visit volume decreased after COVID-19 mitigation measures were implemented in the US beginning on March 16, 2020. Weekly ED visit counts for all 6 outcomes decreased between March 8 and 28, 2020 (March 8: MHCs = 42 903, SAs = 5212, all ODs = 14 543, opioid ODs = 4752, IPV = 444, and SCAN = 1090; March 28: MHCs = 17 574, SAs = 4241, all ODs = 12 399, opioid ODs = 4306, IPV = 347, and SCAN = 487). Conversely, ED visit rates increased beginning the week of March 22 to 28, 2020. When the median ED visit counts between March 15 and October 10, 2020, were compared with the same period in 2019, the 2020 counts were significantly higher for SAs (n = 4940 vs 4656, P = .02), all ODs (n = 15 604 vs 13 371, P < .001), and opioid ODs (n = 5502 vs 4168, P < .001); counts were significantly lower for IPV ED visits (n = 442 vs 484, P < .001) and SCAN ED visits (n = 884 vs 1038, P < .001). Median rates during the same period were significantly higher in 2020 compared with 2019 for all outcomes except IPV. Conclusions and Relevance: These findings suggest that ED care seeking shifts during a pandemic, underscoring the need to integrate mental health, substance use, and violence screening and prevention services into response activities during public health crises.


Subject(s)
COVID-19/epidemiology , Drug Overdose , Emergency Service, Hospital , Mental Disorders , Suicide, Attempted , Violence , Adult , Drug Overdose/epidemiology , Emergency Service, Hospital/statistics & numerical data , Emergency Service, Hospital/trends , Epidemiological Monitoring , Female , Humans , Male , Mental Disorders/epidemiology , Mental Disorders/therapy , Mental Health/statistics & numerical data , Outcome Assessment, Health Care/trends , Patient Acceptance of Health Care/psychology , Patient Acceptance of Health Care/statistics & numerical data , SARS-CoV-2 , Suicide, Attempted/psychology , Suicide, Attempted/statistics & numerical data , United States/epidemiology , Violence/psychology , Violence/statistics & numerical data
16.
Rev. cuba. salud pública ; 46(supl.1):e2696-e2696, 2020.
Article in Spanish | LILACS (Americas), Grey literature | ID: grc-745535

ABSTRACT

RESUMEN Introducción: Ante la presencia de la COVID-19 se han implementado en Cuba medidas dirigidas a la organización del país y de sus servicios de salud en correspondencia con las acciones aprobadas por la Organización Mundial de la Salud para la gestión de riesgos sanitarios. Objetivo: Identificar las acciones implementadas en Cuba para el enfrentamiento de la pandemia por la COVID-19 vinculadas a los componentes de las categorías de la gestión de los riesgos sanitarios en situaciones de emergencia. Métodos: Se desarrolló una investigación con enfoque cualitativo, en la cual se incluyó la revisión de documentos, como artículos científicos, noticias, entre otros, relacionados con la COVID-19 y que abordaran el tema a partir de las categorías y componentes establecidos en la gestión de riesgos sanitarios en situaciones de emergencias. Para evaluar la calidad de la información recuperada en sitios web se utilizaron los parámetros establecidos por Cooke. Conclusiones: La voluntad política del Gobierno cubano, de conjunto con los Organismos de la Administración Central del Estado y el relevante papel desempeñado por el Ministerio de Salud Pública y sus profesionales, han permitido implementar medidas de prevención y control que se corresponden con los componentes incluidos en las categorías de la gestión de riesgos sanitarios en situaciones de emergencia en las fases preepidémicas, epidémicas y de recuperación de la COVID-19. ABSTRACT Introduction: In view of COVID-19 presence, in Cuba has been implemented measures directed to the organization of the country and its health services in accordance with actions approved by the World Health Organizations for sanitary risks´ management. Objective: To identify the actions implemented in Cuba for the fight against COVID-19 pandemic and linked to the components of sanitary risk management's categories in emergency situations. Methods: It was developed a research with qualitative approach, in which it was included review of papers as scientific articles, news, among others related with COVID-19 and which tackled the topic from the categories and components established in the management of sanitary risks in emergency situations. There were used parameters established by Cooke to evaluate the quality of information collected in websites. Conclusions: The political will of the Cuban Government, jointly with the bodies of the State's Central Administration and the outstanding role played by the Ministry of Public Health and its professional workers have allowed to implement control and prevention measures which correspond to the components included in the categories of sanitary risks management in emergency situations in COVID-19 pre-epidemic, epidemic and recovery phases.

17.
Rev. cuba. salud pública ; 46(supl.1):e2696-e2696, 2020.
Article in Spanish | LILACS (Americas) | ID: covidwho-1022862

ABSTRACT

RESUMEN Introducción: Ante la presencia de la COVID-19 se han implementado en Cuba medidas dirigidas a la organización del país y de sus servicios de salud en correspondencia con las acciones aprobadas por la Organización Mundial de la Salud para la gestión de riesgos sanitarios. Objetivo: Identificar las acciones implementadas en Cuba para el enfrentamiento de la pandemia por la COVID-19 vinculadas a los componentes de las categorías de la gestión de los riesgos sanitarios en situaciones de emergencia. Métodos: Se desarrolló una investigación con enfoque cualitativo, en la cual se incluyó la revisión de documentos, como artículos científicos, noticias, entre otros, relacionados con la COVID-19 y que abordaran el tema a partir de las categorías y componentes establecidos en la gestión de riesgos sanitarios en situaciones de emergencias. Para evaluar la calidad de la información recuperada en sitios web se utilizaron los parámetros establecidos por Cooke. Conclusiones: La voluntad política del Gobierno cubano, de conjunto con los Organismos de la Administración Central del Estado y el relevante papel desempeñado por el Ministerio de Salud Pública y sus profesionales, han permitido implementar medidas de prevención y control que se corresponden con los componentes incluidos en las categorías de la gestión de riesgos sanitarios en situaciones de emergencia en las fases preepidémicas, epidémicas y de recuperación de la COVID-19. ABSTRACT Introduction: In view of COVID-19 presence, in Cuba has been implemented measures directed to the organization of the country and its health services in accordance with actions approved by the World Health Organizations for sanitary risks´ management. Objective: To identify the actions implemented in Cuba for the fight against COVID-19 pandemic and linked to the components of sanitary risk management's categories in emergency situations. Methods: It was developed a research with qualitative approach, in which it was included review of papers as scientific articles, news, among others related with COVID-19 and which tackled the topic from the categories and components established in the management of sanitary risks in emergency situations. There were used parameters established by Cooke to evaluate the quality of information collected in websites. Conclusions: The political will of the Cuban Government, jointly with the bodies of the State's Central Administration and the outstanding role played by the Ministry of Public Health and its professional workers have allowed to implement control and prevention measures which correspond to the components included in the categories of sanitary risks management in emergency situations in COVID-19 pre-epidemic, epidemic and recovery phases.

18.
Insights Imaging ; 12(1): 1, 2021 Jan 04.
Article in English | MEDLINE | ID: covidwho-1007145

ABSTRACT

BACKGROUND: Possible COVID-19 pneumonia patients (ppCOVID-19) generally overwhelmed emergency departments (EDs) during the first COVID-19 wave. Home-confinement and primary-care phone follow-up was the first-level regional policy for preventing EDs to collapse. But when X-rays were needed, the traditional outpatient workflow at the radiology department was inefficient and potential interpersonal infections were of concern. We aimed to assess the efficiency of a primary-care high-resolution radiology service (pcHRRS) for ppCOVID-19 in terms of time at hospital and decision's reliability. METHODS: We assessed 849 consecutive ppCOVID-19 patients, 418 through the pcHRRS (home-confined ppCOVID-19 with negative-group 1- and positive-group 2-X-rays) and 431 arriving with respiratory symptoms to the ED by themselves (group 3). The pcHRRS provided X-rays and oximetry in an only-one-patient agenda. Radiologists made next-step decisions (group 1: pneumonia negative, home-confinement follow-up; group 2: pneumonia positive, ED assessment) according to X-ray results. We used ANOVA and Bonferroni correction, Student T, Chi2 tests to analyse changes in the ED workload, time-to-decision differences between groups, potential delays in patients acceding through the ED, and pcHRRS performance for deciding admission. RESULTS: The pcHRRS halved ED respiratory patients (49.2%), allowed faster decisions (group 1 vs. home-discharged group 2 and group 3 patients: 0:41 ± 1:05 h; 3:36 ± 2:58 h; 3:50 ± 3:16 h; group 1 vs. all group 2 and group 3 patients: 0:41 ± 1:05 h; 5.25 ± 3.08; 5:36 ± 4:36 h; group 2 vs. group 3 admitted patients: 5:27 ± 3:08 h vs. 7:42 ± 5:02 h; all p < 0.001) and prompted admission (84/93, 90.3%) while maintaining time response for ED patients. CONCLUSIONS: Our pcHRRS may be a more efficient entry-door for ppCOVID-19 by decreasing ED patients and making expedited decisions while guaranteeing social distance.

20.
MMWR Morb Mortal Wkly Rep ; 69(45): 1675-1680, 2020 Nov 13.
Article in English | MEDLINE | ID: covidwho-922982

ABSTRACT

Published reports suggest that the coronavirus disease 2019 (COVID-19) pandemic has had a negative effect on children's mental health (1,2). Emergency departments (EDs) are often the first point of care for children experiencing mental health emergencies, particularly when other services are inaccessible or unavailable (3). During March 29-April 25, 2020, when widespread shelter-in-place orders were in effect, ED visits for persons of all ages declined 42% compared with the same period in 2019; during this time, ED visits for injury and non-COVID-19-related diagnoses decreased, while ED visits for psychosocial factors increased (4). To assess changes in mental health-related ED visits among U.S. children aged <18 years, data from CDC's National Syndromic Surveillance Program (NSSP) from January 1 through October 17, 2020, were compared with those collected during the same period in 2019. During weeks 1-11 (January 1-March 15, 2020), the average reported number of children's mental health-related ED visits overall was higher in 2020 than in 2019, whereas the proportion of children's mental health-related visits was similar. Beginning in week 12 (March 16) the number of mental health-related ED visits among children decreased 43% concurrent with the widespread implementation of COVID-19 mitigation measures; simultaneously, the proportion of mental health-related ED visits increased sharply beginning in mid-March 2020 (week 12) and continued into October (week 42) with increases of 24% among children aged 5-11 years and 31% among adolescents aged 12-17 years, compared with the same period in 2019. The increased proportion of children's mental health-related ED visits during March-October 2020 might be artefactually inflated as a consequence of the substantial decrease in overall ED visits during the same period and variation in the number of EDs reporting to NSSP. However, these findings provide initial insight into children's mental health in the context of the COVID-19 pandemic and highlight the importance of continued monitoring of children's mental health throughout the pandemic, ensuring access to care during public health crises, and improving healthy coping strategies and resiliency among children and families.


Subject(s)
Coronavirus Infections/psychology , Emergency Service, Hospital/statistics & numerical data , Mental Disorders/therapy , Pandemics , Pneumonia, Viral/psychology , Adolescent , COVID-19 , Child , Child, Preschool , Coronavirus Infections/epidemiology , Female , Humans , Male , Mental Disorders/epidemiology , Pneumonia, Viral/epidemiology , United States/epidemiology
SELECTION OF CITATIONS
SEARCH DETAIL