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Introduction: There is a distinct unmet need in structured, curriculum based, unbiased education in neuromodulation. Current teaching is through sporadic industry workshops, cadaver courses and peer proctorship. The COVID pandemic has created a unique opportunity where online platforms have enabled education to be delivered remotely in both synchronous and asynchronously. The William Harvey Research Institute, Queen Mary University, London, UK have initiated University based accreditation- Post Graduate Certificate in neuromodulation (PGCert) that provides candidate a qualification in one academic year through part-time study. Method(s): The program underwent rigorous staged university approval process (figure 1). To ensure market feasibility, two short proof of concept CPD programs "Executive Education in Neuromodulation (EEPIN)" were delivered in 2021. These courses attracted 87 candidates across Australia, Singapore, India, Germany, Poland, Czech Republic, Ireland, and UK. The faculty includes key opinion leaders that will deliver the program ensuring the candidates gain academic background and specialist skills to understand safe practice of neuromodulation. The PGCert advisory board has been established to ensure strict governance in terms of content and unbiased delivery confirming ACCME guidance. In order to obtain PGCert, candidates are required to complete 4 x 15 credit modules (60 credits). The four modules include Anatomy & Neurophysiology;Patient care and Procedurals skills;Devices and available technology;Intrathecal drug delivery for cancer and non-cancer pain. The modular nature of the program is designed to provide cumulative knowledge, from basic science to clinical application in line with the best available evidence. The modules comprise nine lectures, spreading over three consecutive days, followed by a written assignment with 40 direct contact hours in each module. The webpage can be accessed at Results: The anonymous data from EEPIN reported on Likert scale 1-5: Objectives defined 30.6% - 4 and 69.4% -5;Relevance of topics 10.2%- 4 and 89.8% -5;Content of presentations 22.4%- 4 and 77.6% -5;Organization 24.5% -4 and 69.4% -5;Candidate faculty interaction 14.3% -4 and 81.6% -5. 97% of the EEPIN candidates recommended the program to others whilst 81.8% expressed their strong interest to enroll for university-based post graduate qualification if offered. Conclusion(s): This PGcert Neuromodulation is a unique, university accredited program that provides qualification in neuromodulation with access to a flexible online e-learning platform to discuss and exchange ideas, share knowledge in candidate's own time. This will support the ongoing need for formal curriculum-based education in neuromodulation. Disclosure: Kavita Poply, PHD: None, Phillippe Rigoard: None, Jan Kallewaard, MD/PhD: None, FRANK J.P.M. HUYGEN, MD PhD: ABBOTT: Speakers Bureau:, Saluda: Consulting Fee:, Boston Scientific: Consulting Fee:, Grunenthal: Speakers Bureau:, Pfizer: Speakers Bureau:, Ashish Gulve, FRCA, FFPMRCA, FFPMCAI, DPMed, FCARCSI, MD, MBBS: None, Ganesan Baranidharan, FRCA: None, Sam ELDABE, MD, FRCA, FFPMRCA: Medtronic: Consulting Fee:, Medtronic: Contracted Research:, Mainstay Medical: Consulting Fee:, Saluda Medical: Consulting Fee:, Boston Scientific: Contracted Research:, Saluda Medical: Contracted Research:, James Fitzgerald, MA,PhD: St Jude Medical: Consultant: Self, Medtronic: Consulting Fee:, UCB: Contracted Research:, Merck: Contracted Research:, Serge Nikolic, MD: None, Stana Bojanic, BSc MBBS FRCS (SN): Abbott: Contracted Research:, Habib Ellamushi: None, Paresh Doshi, MS MCh: None, Preeti Doshi, MBBS, MD, FRCA: None, Babita Ghai, MBBS, MD, DNB: None, Marc Russo, MD: Presidio Medical: Ownership Interest:, Saluda Medical: Ownership Interest:, Boston Scientific: Contracted Research: Self, Mainstay Medical: Contracted Research: Self, Medtronic: Contracted Research: Self, Nevro: Contracted Research: Self, Saluda Medical: Contracted Research: Self, Presidio Medical: Contracted Research: Self, Freedom Ne ro: Ownership Interest - Own Stocks: Self, Lungpacer: Ownership Interest - Own Stocks: Self, SPR Therapeutics: Ownership Interest - Own Stocks: Self, Lawrence Poree, MD,MPH,PHD: Medtronic: Consulting Fee: Self, Saluda Medical: Contracted Research: Family, Nalu Medical: Contracted Research: Family, Gimer Medical: Consulting Fee: Self, Nalu Medical: Consulting Fee: Self, Saluda Medical: Consulting Fee: Self, Nalu: Ownership Interest:, Saluda Inc: Ownership Interest:, Alia Ahmad: None, Alaa Abd Sayed, MD: Medtronic, Abbott, SPR and StimWave: Consulting Fee:, Salim Hayek, MD,PhD: None, CHRISTOPHER GILLIGAN, MD MBA: Persica: Consulting Fee: Self, Saluda: Consulting Fee: Self, Mainstay Medical: Contracted Research: Self, Sollis Therapeutics: Contracted Research: Self, Iliad Lifesciences, LLC: Owner: individuals with legal ownership in a company:, Vivek Mehta: NoneCopyright © 2023
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Introduction: Bart's Neuromodulation Centre is a center of excellence for research and innovation. In the UK, the NICE 159 guidelines have highlighted the importance of psychological and multidisciplinary assessment to ascertain the suitability of patients for Neuromodulation. The global pandemic of Covid-19 has had far-reaching physical, psychological, and socioeconomic implications. Despite the various limitations of running services during a pandemic, Barts Neuromodulation Centre maintained the importance of multidisciplinary assessment in the selection of patients suitable for this form of therapy. This paper presents psychological wellbeing outcomes of neuromodulation patients during this unprecedented period. Method(s): Data collection was gathered remotely between January 2021 to December 2021.N=178 completed questionnaires. The mean age was 55 years and 63% were female. Data was collected at baseline and in addition, post-implant data was obtained at 1,3,6 and 12 month follow up. As per NHS England outpatient guidance (2020), all data was completed remotely. All collected data was anonymized and data was stored on an encrypted database. Result(s): Results showed a 78% decrease in depression scores from baseline to 2 years+ and a 76% decrease in anxiety scores from baseline to 2 years+. Conclusion(s): The data demonstrates significant improvements in psychological wellbeing as shown in depression and anxiety scores after SCS therapy. Despite the global pandemic, there remains a strong demand for SCS and encouragingly showed significant improvements in psychological wellbeing. It would be useful to explore ways to improve patient compliance and explore broader parameters of outcomes. Disclosure: Angie Alamgir, PHD: None, Serge Nikolic, MD: None, Habib Ellamushi: None, Amin Elyas, FRCS: None, Joanne Lascelles, Clinical nurse specialist: None, Kavita Poply, PHD: None, Sanskriti Sharma: None, Alia Ahmad, MSc: None, Vivek Mehta: NoneCopyright © 2023
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Introduction: Covid-19 was classed as a global pandemic by the World Health Organization (WHO) in March 2020. This had an overwhelming effect on the National Health Services (NHS) in the United Kingdom resulting in the disruption and subsequent prioritization of the elective recovery services. Despite the various limitations of delivering services during a pandemic, Barts Neuromodulation Centre maintained the importance of multidisciplinary assessment in the selection of patients suitable for this form of therapy. We present the data on our continued activity through pandemic, dependent on the performance feasibility. The aim of this effectiveness project was to evaluate the post SCS outcome data during covid-19 pandemic. Method(s): This was a telephone and in person data collection of patient responses to standardized and validated pain outcome questionnaires following SCS implant performed at St Bartholomew's Hospital, London during January-December 2021. Data was collated from a tertiary Neuromodulation center at Barts Health NHS Trust, UK. Patients completed the questionnaires prior to SCS implant and post implant 1, 3, 6, and 12 month follow- up appointments with our neuromodulation specialists Results: Two hundred and fifteen patients underwent face to face or telephonic consultation during January to December 2021 for the follow ups. Total 178 patients registered their responses with F:M being 63%:37% and the average age 55 years. At each time point, the following number of patients completed: baseline n= 52;1 month n= 27;3 months n=28;6-month n= 21 and 12 months, n= 26. We demonstrate that NRS pain scores reduced by 43%, ODI disability improved by 35%, HADS anxiety reduced by 45%, depression reduced by 46%, PSQ sleep improved by 77% and EQ5D quality of life improved by 66% at 12 months when compared to baseline. There were no serious adverse events reported through this time. Conclusion(s): To our knowledge, this is one of the first reported real-world post SCS outcome data of prospective follow ups. We demonstrate safe delivery of services and data collection feasibility through pandemic. Moreover, our patient cohort showed improvement in the all dimensions of chronic refractory pain following SCS therapy despite clinical burden of COVID-19. Disclosure: Alia Ahmad: None, Angie Alamgir, PHD: None, Sanskriti Sharma: None, Joanne Lascelles, Clinical nurse specialist: None, Amin Elyas, FRCS: None, Helen Bonar: None, Serge Nikolic, MD: None, Habib Ellamushi: None, Vivek Mehta: None, Kavita Poply, PHD: NoneCopyright © 2023
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Just as the country has recently dealt with the increase in COVID-19 and monkey pox cases, another dark cloud of "Tomato flu/ Tomato fever " loomed the skies of the nation. As of 24 august, 2022, 100 kids mainly below the age of 5 have been reported showing symptoms of the flu. Another state of Odisha, suspected similar infectious etiology in 36 cases out of which 26 Children were below the age of 10. This endemic viral illness has triggered an alert to the neighboring states of Tamil Nadu and Karnataka, along with the entire nation at large. The wrath of this disease is not just restricted to India but crossing borders. Tang, et al reported a case of a 13-month-old female child and her 5-year old brother based in United kingdom with similar etiology. Through this report, we aim to alert the frontline pediatricians, who are most likely to come across and manage such daunting cases with these non-specific clinical features in their routine clinical practice across the globe. Early and extreme preventive and surveillance measures must be undertaken to prevent substantial loss in public and private sector Mehta et al.
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Our retrospective study aimed to evaluate the effectiveness of monoclonal antibodies (casirivimab and imdevimab) on mild cases of coronavirus disease 2019 patients admitted to the tertiary care center. A total of 161 patients were evaluated of which the test group consisted of 79 and the control group of 82. In the test group the patients had been administered with diluted 250 ml of 0.9 % sodium chloride along with co-formulated casirivimab (600 mg) and imdevimab (600 mg) solution intravenously and in the control group the patients were administered standard coronavirus disease 2019 treatment protocol. The monitoring of patients in both groups was done at least 1 h after drug infusion in the designated room. Post-treatment designed interviews were taken to evaluate the effectiveness of treatment. This retrospective analysis discovered a significant association of symptoms with the group at 48 h for injected and non-injected patients and 1 mo from the chi-square test after injecting monoclonal antibodies. There is no significant association of symptoms with the groups at 3 mo. A significant difference in the symptom distribution through different time points in the injected group and not injected group was observed. From the pairwise McNemar's test, a significant difference in the symptoms between each time in 48 h, the difference was p=0.0075 and after 1 mo, p<0.001 points in both groups. The combination of casirivimab and imdevimab could be considered a treatment of choice for vaccinated, non-vaccinated and mild to highrisk coronavirus disease 2019 patients.
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Introduction: Bart's Neuromodulation Centre is a centre of excellence for research and innovation. In the UK, the NICE 159 guidelines have highlighted the importance of psychological and multidisciplinary assessment to ascertain the suitability of patients for Neuromodulation. It is widely acknowledged that the global pandemic of Covid-19 has had far-reaching physical, psychological and socioeconomic implications. Despite the various limitations of running services during a pandemic, Barts Neuromodulation Centre maintained the importance of multidisciplinary assessment in the selection of patients suitable for this form of therapy. This paper presents psychological wellbeing outcomes of neuromodulation patients during this unprecedented period. Materials / Methods: Data collection was gathered remotely between January 2021 to December 2021.N=178 completed questionnaires. The mean age was 55 years and 63% were female. Data was collected at baseline and in addition, post-implant data was obtained at 1,3,6 and 12 month follow up. As per NHS England outpatient guidance (2020), all data was completed remotely. All collected data was anonymized and data was stored on an encrypted database. Result(s): Graph 1: HADS Depression Scores [Formula presented] Graph 1 demonstates a 78% decrease in depression scores from baseline to 2 years+ Graph 2: HADS Anxiety Scores [Formula presented] Graph 2 demonstrates a 76% decrease in anxiety scores from baseline to 2 years+. Discussion(s): The data demonstrates significant improvements in psychological wellbeing as shown in depression and anxiety scores after SCS therapy. It would be useful to explore ways to improve patient compliance and explore broader parameters of outcomes. Conclusion(s): Despite the global pandemic, there remains a strong demand for SCS and encouragingly showed significant improvements in psychological wellbeing. Learning Objectives: 1. Evaluate clinical outcomes 2. Understand the impact of a global pandemic on clinical outcomes 3. Delivering remote clinical care and data collection. Keywords: Anxiety, depression, Pain, SCS, neuromodulation, LBP Copyright © 2022
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Introduction: Bart's Neuromodulation Centre is a centre of excellence for research and innovation. In the UK, the NICE 159 guidelines have highlighted the importance of multidisciplinary assessment to ascertain the suitability of patients for Neuromodulation and prehab in preparation for an SCS procedure. It is widely acknowledged that the global pandemic of Covid-19 has had far-reaching physical, psychological and socioeconomic implications. Despite the various limitations of delivering services during a pandemic, Barts Neuromodulation Centre maintained the importance of multidisciplinary assessment in the selection of patients suitable for this form of therapy. Effective use of video clinics for MDT clinics and remote data collection have been vital in maintaining service delivery. This paper presents a collection of outcomes following neuromodulation intervention during this unprecedented period. Materials / Methods: Data collection was gathered remotely between January 2021 to December 2021.N=178 completed questionnaires. The mean age was 55 years and 63% were female. Data was collected at baseline and in addition, post-implant data was obtained at 1,3,6 and 12 month follow up. As per NHS England outpatient guidance (2020), all data was completed remotely. All collected data was anonymized and data was stored on an encrypted database. Result(s): [Formula presented] Figure 1 shows an overall pain reduction over 12 months. [Formula presented] Figure 2 shows improvements in anxiety and depression scores from HADS. [Formula presented] Figure 3 displays reduction in disability scores. [Formula presented] Figure 4 shows improvements on pain and sleep. [Formula presented] Figure 5 demonstrates improvements in QOL scores. Discussion(s): Despite the Covid-19 pandemic, patients reported welcomed improvements in pain scores, disability, psychological wellbeing, sleep and quality of life. The data suggests a reduction in pain scores by 43%, an improvement in disability by 35%, reduction in anxiety and depression to 45% and 46% respectively, an improvement in sleep by 77% and lastly quality of life by 66%. Conclusion(s): Despite the global pandemic, there remains a strong demand for SCS and encouragingly data showed significant improvements in a range of outcomes. Learning Objectives: 1. Evaluate clinical outcomes 2. Understand the impact of a global pandemic on clinical outcomes 3. Impact of delivering remote clinical care and remote data collection. Keywords: Pain, outcomes, neuromodulation, SCS, COVID-19, LBP Copyright © 2022
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Background: The 2019 novel coronavirus (COVID-19) has been associated with elevated liver enzymes, which has seen to be associated with a higher mortality rate in COVID-19 infected patients. With a global vaccination rate under 50%, as of November 2021, we will continue to see patients admitted for COVID-19 infection. We have done this study to further evaluate the relationship between development of transaminitis and its relation to vaccination status and to see if vaccination prevented liver injury in COVID-19 patients. Methods: A retrospective study was performed between October 2019 and October 2021 on patients infected with COVID-19. A total of three hundred and fifty patient charts were included in the study. Patient data regarding age, sex, comorbidities, vaccination status, vaccine manufacturer, mortality, and length of stay data were reviewed. Patients were then divided into two groups (Vaccinated vs Unvaccinated ), data was then matched for their age, sex, and comorbidities using propensity score matching. Results: Each group had thirty-nine patients after propensity score matching. The average age in both groups was 58.4±13.3. Twenty-one females were in a non-vaccinated group and twenty females in the vaccinated group. The average number of days to infection from the last COVID-19 vaccine was 132±57. The vaccinated group showed a significant reduction in the incidence of liver injury with respect to AST (42±13 vs. 93.3±35, P< 0.02, 95% CI), ALT (50±10 vs. 97.4±45.5 P<0.04), and ALP 65±15.2 vs. 93±35.6 P<0.01) compared to unvaccinated patients. The vaccinated patient group showed a reduced length of stay compared to the unvaccinated group ( 10.6 ± 4.8 vs. 18.1 ± 8.1, P<0.05). The vaccinated patient group showed a decrease in mortality as compared to the unvaccinated group (17 vs. 8, P<0.05). Conclusion: After a thorough review of COVID infected patients, liver enzyme abnormalities were evaluated in vaccinated and unvaccinated patients. ALT, AST, and ALP in vaccinated patients were found to be significantly lower in as compared to unvaccinated patients. Hospital length of stay and mortality rate were both found to be lower in vaccinated patients compared to unvaccinated patients. Recent vaccination status leading to decreased infection severity may relate to the lack of significant and dramatic increase in liver enzyme levels and may present as confounding factors. Major limitation in the study was the small sample size and future studies with a larger sample size can deliver a better perspective.
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Fake news confronts us on a daily basis in today’s fast-paced social media world. While some instances of fake news might seem innocuous, there are many examples that prove to be menacing. Misinformation or disinformation which takes the form of these weaponized lies which eventually amount to defective information, defamatory allegations, and hoaxes. The only motive behind such a malicious act is to engender emotional instability among the public. One such prevalent example today is COVID-19 which has caused an unprecedented paradigm shift in numerous businesses and quotidian activities across the globe. One of the primary activities is being news reporting. On average, people are spending almost one hour a day reading news via many different sources. The development in technology has obviated the barriers between sharing of information, thereby truly making the industry cosmopolitan. Therefore, it is paramount to curb fake news at source and prevent it from spreading to a larger audience. This paper describes a system, where the user can identify apocryphal news related to COVID-19 so as to ensure its authenticity. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
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Objectives: Hospital resource usage is under constant review, and the extent and intensity of postoperative care requirements for vascular surgical procedures has been especially relevant in the setting of the COVID-19 (coronavirus disease 2019) pandemic and its impact on staffed intensive care unit (ICU) beds. We evaluated the feasibility of regional anesthesia and low-intensity postoperative care for patients undergoing transcarotid artery revascularization (TCAR) at our institution. Methods: All patients at high risk for carotid endarterectomy undergoing TCAR at a single institution from 2018 to 2020 were reviewed. Perioperative management was standardized by the use of an institutional protocol that included hemodynamic parameters and requisite medications, anticoagulation and/or antiplatelet regimens, neurovascular examination guidelines, and nursing instructions. The anesthetic modality was at the surgeon’s preference. Patients were transferred to the postanesthesia care unit (PACU) for 2 hours (with a 1:1 or 1:2 nursing ratio) followed by the step-down unit (1:4 nursing ratio) for 4 hours, followed by transfer to the floor (1:6 ratio) or, alternatively, were transferred to the ICU (1:1 ratio). Intravenous (IV) blood pressure medications could be administered in all environments, except for the floor. The recovery location and length of stay were recorded. Results: A total of 83 patients had undergone TCAR during the study period. The mean age was 72 ± 9 years, 59% were men, and 36% were symptomatic. Regional anesthesia was used for 84%, with none converted to general anesthesia intraoperatively. Postoperatively, only seven patients (8%) had required monitoring in the ICU overnight (decided perioperatively). This was mostly for patients with prior neurologic symptoms but for one patient was because of a postoperative neurologic event and for another patient because of pulseless electrical activity arrest. Of the 83 patients, 76 (92%) had been monitored in the PACU, with 8 transferred to the floor after 4 hours and 13 discharged directly from the PACU (owing to limited bed availability). Of the patients in the PACU, 55 were transferred to the step-down unit after 2 hours and discharged from there. Six patients had required IV antihypertensive agents, and eight had required IV vasoactive support postoperatively. The mean length of stay in the ICU was 3.7 days (range, 1-15 days). The mean length of hospital stay was 1.8 ± 2.3 days (3.7 ± 5.4 days for those requiring the ICU and 1.4 ± 1.2 days for those not requiring the ICU). The incidence of stroke, death, and myocardial infarction was 2.4%. There was one postoperative stroke considered to be a recrudescence of a prior stroke, and one respiratory arrest fatality in a frail patient with a neck hematoma, both of whom had been treated under general anesthesia. Conclusions: Using perioperative care protocols, TCAR can safely be performed while avoiding both general anesthesia and an ICU stay for most patients.
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Introduction: The airway management of patients with COVID-19 is a high risk task for anaesthesiologists. Several innovations have been born as a result of this problem, including aerosol boxes and clear plastic sheets. Aim: To compare the timing and attempt of direct laryngoscopy with and without aerosol box for intubation in patients undergoing general anaesthesia during the COVID-19 pandemic. Materials and Methods: This was a randomised controlled study was conducted in Parul Sevashram Hospital, Parul University, Vadodara, Gujrat, India from April 2021 to September 2021. A total of 50 patients were randomly divided into two equal groups as group A was intubated with an aerosol box and a macintosh laryngoscope, while group B was intubated with a clear plastic sheet and macintosh laryngoscope. With proper airway precautions and Personal Protective Equipments (PPE) comparative assessment of patients undergoing surgery in general anaesthesia was done. Time to intubate, number of attempts, ease of Endotracheal Tube (ETT) tube insertion, quality of Laryngoscopy view and Cormack Lehane scores were assessed in both the groups. Results: The mean time for intubation was high at 29.72 seconds in group A, while it was 23.16 seconds in group B;the difference was significant. Overall, 20 out of 25 (80%) patients could be intubated in 1st attempt in group B as compared to 15 out of 25 (60%) in group A. Airway visualisation using Percentage of Glottic Opening (POGO) scoring and Cormack Lehane staging were suggestive of better visualisation in group B than group A. Difficulties encountered during intubation like laryngoscopy, glottic visualisation, arm movement restriction, ETT negotiation, and stylet removal were lesser in group A as compared to group B. The incidence of complications like sore throat and airway bleeding were lower in group B as compared to group A. Conclusion: In the COVID-19 era, aerosol box and clear plastic sheets are effective barrier measures for airway management to prevent the anaesthesiologists from the aerosol transmission. But airway management with clear plastic sheet is technically easier than aerosol box.
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Background: The clinical presentation of Covid-19 positive person can range from asymptomatic to severe pneumonia with acute respiratory diseases. The major impact of Covid-19 is identified on respiratory system of the human and leading to death. There are different types of treatment options available for managing the health of the people but first was remdesivir that approved by the FDA. The dexamethasone has been associated with decreased mortality in recovery of the medicine trail. Apart from this, the major benefits of interleukin 6 antagonists are still subject of debate as tocilizumab FDA approved the interleukin 6 for treatment considering the side effects too. Aim: The study aims to assess the role of tocilizumab with or without remdesivir in COVID-19 diabetic patients Method: The current study is retrospective, single centered, observational cohort and based on the patients who were diagnosed with Covid-19 considering the PCR test and hospitalized at ESI Chitrakoot Nagar, Udaipur under RNT Medical College, Udaipur from October-20 to December-21. The study has involved the patients who were 18 years and older and had the clinical association with diabetes mellitus. Moreover, the respiratory findings also defined as infiltrates, SPO2 < 93% on room air and requirements of respiratory assistance. For the current study, the data was collected related to demographics, co-morbidities, symptom, oxygen support category, laboratory values and outcome of the therapies. The level of oxygen support was analyzed considering the ACTT-1. Results: There were total of 127 patients considered for analyzing the role of tocilizumab with or without remdesivir in COVID-19 diabetic patients. The group 1 is involving the 54 patients and group 2 has 73 covid-19 patients. According to the outcome of the analysis, the mean age of both groups were 62 and 64 years for group 1 and 2. There was significant difference identified for respiratory support received by the patients and obesity, COPD and CVD. However, there was no significant difference found for diabetes patients as the P value was more than 0.05. As per the outcome of the study focusing on the Chi Square, most of the variables have shown significant difference but Remdesivir, and low vitamin D levels have shown the no significant difference Conclusion: From the analysis, it has been concluded that the combinations of tocilizumab and remdesivir did not have any significant difference in mortality but the patients who recovered from the covid-19 has influenced with diabetic issues. The improvement in practice and advancement in laboratory trail has helped to improve the effectiveness of these treatment options.
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The importance of social media has seen a huge growth in last few years as it lets folks from any part of the world remain in contact. Due to COVID-19 epidemic, social media is used extensively and has turned to be more pertinent than the past years. Alongside, fake news dissemination has revived and also dissemination of tweets has taken the attention. For the present study, we used various machine learning models to detect the fake news on COVID-19 related tweets. Due to millions of active social media users, identifying the fake news has become a crucial task. The models we applied are Gradient Boosting Classifier (GBC), Logistic Regression (LR), Random Forest Classifier (RFC), Decision Tree Classification (DT). All these models detect if the tweet relating to COVID-19 is “Fake News” or “Not a Fake News”. Hence we conclude that Logistic Regression is best among all other models. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
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Background: The COVID-19 pandemic is badly affecting more than 2 million population of 213 countries and has caused 1,952,976 deaths till January 12, 2020. India has also suffered a great loss in terms of economy and people. Furthermore, owing to the complete lockdown enforced in India, restricting humanitarian movement also affected day-To-day life of Indians with a huge impact. Objectives: The present clinical trial was carried out to evaluate the impact of the COVID-19 pandemic on private practitioners. Furthermore, changes in their practice pattern were evaluated along with the perspective of their health, role, and response to the pandemic. Materials and Methods: The study includes a total of 120 health-care professionals of either gender. The stress and mental health of the participants was assessed using Depression Anxiety Stress Scale-21 in English format, also included the questions related to the demographic characteristics, use of technologies for providing virtual health care, changes in the working during the pandemic, and an opinion of their experiences during that period. The data collected were subjected to the analysis and were kept confidential and anonymous. Results: 16.6% of participants preferred virtual consultation before the pandemic in contrast to 83.3% during the pandemic. The most preferred method remained the phone call by 15.8% (n = 19) patients. Depression was seen severely in 35% of study participants (n = 42) and 13.3% of participants extremely severe depression was seen (n = 16). Severe and extremely severe anxiety was noticed in 31.66% (=38) and 15% (18) study participants respectively, whereas severe and extremely severe stress was found in 30% (n = 36), and 12.5% (n = 15) private practitioners. The most common factor that can be considered responsible for compromised mental health in private practitioners was the possibility of infecting the society seen in 59.1% (n = 71) participants. Conclusion: During the pandemic breakout, private practitioners suffered a great challenge both financially and mentally, especially during the lockdown. Furthermore, a significant increase was seen in the virtual consultation methods during the pandemic breakout.
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Background the worldwide pandemic SARS - CoV-2 causes Covid-19, a communicable disease. Because health care employees have a higher risk of contracting Covid-19 infection than the general population due to the frequency and duration of interaction with Covid-19 positive patients, protecting health care workers should be a top priority. Aims & objectives the goal of this study is to find out how often Covid-19 vaccination acceptance and reluctance are, as well as the socio-demographic and other factors that influence it. Material and Methods this two-month cross-sectional study was carried out at five tertiary healthcare centers in Central India. A Google form containing the study's structured questionnaire was distributed to health care employees through email, WhatsApp, and text message. Age, gender, occupation, income, marital status, h/o co-morbidities, desire, acceptance, hesitation, and reason for not obtaining the Covid-19 vaccine are all investigated. Results a total of 824 HCWs took part in the study and completed the questionnaire, with 470 (57%) males and 354 (43%) women. The majority of the participants were between the ages of 18 and 30. (50 percent). The majority of those who took part were doctors (77 percent). Covid 19 vaccination was given to about 68 percent of HCWs. Only 13% of HCWs had co-morbidities, with the remaining 87 percent having no co-morbidities. 19% of the HCWs had previously tested positive for Covid-19, whereas 81 percent had previously tested negative. HCWs with a family member who had Covid-19 accounted for 27% of the total. About 37% of HCWs strongly agreed that the vaccine will protect them from the sequelae of Covid-19 illness, while only 4% disagreed and 0.5 definitely disagreed. Nearly 48 percent of HCWs were entirely confident in utilizing locally manufactured Covid-19 vaccine, but just 23 percent were confident in using foreign (imported) vaccine. Approximately 46% of HCWs agreed that the vaccine would protect them from Covid-19 illness. Conclusion HCWs' attitudes toward the Covid-19 vaccination vary depending on their age, education, occupation, and income. HCWs' vaccine knowledge should be improved in order to boost immunization coverage among them and the general public. © 2022 MEDIC SCIENTIFIC. All right reserved.
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Purpose: A government funded;interactive cloud storage platform (www.vcreate.tv/neuro) allowing patients and carers to upload video and linked metadata for neurological diagnosis was established during the Covid-19 pandemic. We describe the utility for epilepsy and paroxysmal disorders in 16 centres with the first centre active from 01/05/2020. Method: Users are invited to register and utilise a password and passcode for access. Videos are uploaded with a structured history. The clinician classifies seizure type, syndrome, aetiology or other diagnosis using drop-down menus. Users and clinicians complete online evaluations. Postcode allows linkage to user index of deprivation score. Consents for teaching by the local clinical team and research within a national neurology video research database with research ethics approval are optional. All data, except the video file, transfer to the electronic patient record. Result: To 24/03/2021, 4582 video uploads (4024 paediatric, 558 adult), 1889 patients (1594 paediatric, 295 adult). 400-600 new videos per month. 323 physician and nurse users. Deprivation scores indicate equitable use across socio-economic groups. Paediatric classification: non-epileptic 55%, epileptic (36.5%), unknown (8.5%). Adult: non-epileptic 73.5% (34% dissociative, 41% movement disorders), epileptic 11%, unknown 15.5%. Paediatric seizure types include: focal impaired awareness (19%), generalised tonic clonic (18%), focal clonic (17%), epileptic spasms (13%). Non-epileptic events: tics (13%), normal behaviour (12%), sleep myoclonus (10%) gratification (8%), dissociative (5%). >95% carers ranked the system positively. Clinicians report video prevented face-to-face review in 57%, investigations in 44% and reduced time to diagnosis in 97%. Median time to review video and classify was 5 minutes. Conclusions: Remote care is facilitated, investigations prevented or prioritised, with rapid diagnosis and efficiencies in the patient pathway. A rapidly growing teaching resource and research database for semiology and machine learning diagnostics for paroxysmal disorders has been established. We plan to establish the system in low-income countries without cost.