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1.
European journal of public health ; JOUR(Suppl 3), 32.
Article in English | EuropePMC | ID: covidwho-2101584

ABSTRACT

Background The COVID-19 pandemic has severely impacted older people. The disease and the measures to combat it have had a differential impact according to gender, with higher mortality rates in men and worse psychological and social consequences in women. The objective of this work is to analyze the changes in perceived health of older people in Europe during the first months of the pandemic and to assess the combined role of age and gender. Methods Wave 8 data of SHARE-corona (Survey of Health, Aging and Retirement in Europe) (n = 51,695, aged≥50) collected between Jun-Aug 2020 were used. Perceived health status was explored with a question on whether there has been a change compared with the health status before the COVID-19 outbreak (response options: worse, the same and better). Two-way ANOVA with interaction and Student's t-test with Bonferroni correction were used to compare the effects of gender and age group (50-59 years, 60-69 years, 70-79 years, and ≥80) in changes in perceived health. Results Differences in perceived health were observed by age, as well as by gender in participants aged ≥70 years (F = 91.94;p < 0.001). These differences were significant both by gender (F = 19.39;p < 0.001) and age (F = 191.79;p < 0.001). No interaction was detected between both factors (p = 0.170), which allowed their effect to be studied individually. Among the people who reported a worsening in their perceived health, women aged 70 to 79 years predominated (11.1%), followed by men aged 80 and over (15.3%) and women of the same age group (16.4%). Conclusions The results suggest an association between the change in perceived health during the pandemic and age. Women have a slightly worse health status than men in all age groups. Therefore, gender can be considered as an influential factor in perceived health in old age, which in turn can have a potential impact in the quality of life of older people. Funding Projects Ref. H2019/HUM-5698 and Ref. 202010E158. Key messages Older people have been severely impacted by COVID-19 pandemic. The combined effect of age and gender on the change in perceived health status during the pandemic have been analyzed.

2.
1st LACCEI International Multi-Conference on Entrepreneurship, Innovation, and Regional Development: Ideas to Overcome and Emerge from the Pandemic Crisis, LEIRD 2021 ; 2021.
Article in Spanish | Scopus | ID: covidwho-2081208

ABSTRACT

This research article describes the importance of the English language as a foreign language within a inquiry, gamification, autonomous learning and digital reading process. The main objective was about developing a digital proposal that would promote the use of technical English applied to the reading plan in some courses of the civil engineering program through a virtual environment, it was based on interactive and digital magazines. They worked about the civil engineering discipline and they were focused on the ESP methodology. It was framed within the reading plan established through the syllabus of the four disciplinary courses. The mandatory quarantine situation generated by Covid-19 made part of the methodological process and fieldwork research. Just because it was 100% virtual. The research was carried out using a correlational quantitative methodological. The intervened sample was 161 students. Talking about the results obtained, it is highlighted that the reading plan proposed from the digital magazines enhanced the level of English to the civil engineering students, it was according to statistical facts used to measure different aspects from the type of research selected. The situation of virtualized education was used to strengthen disciplinary themes about civil engineering program and foreign language skills. © 2021 Latin American and Caribbean Consortium of Engineering Institutions. All rights reserved.

3.
American Journal of Transplantation ; 22(Supplement 3):761, 2022.
Article in English | EMBASE | ID: covidwho-2063535

ABSTRACT

Purpose: The evidence regarding the clinical effectiveness of COVID-19 vaccination in kidney transplant (KT) recipients is limited so far. Our purpose is to analyze the characteristics and outcomes of a large series of KT with COVID-19 breakthrough infection and compare them with unvaccinated patients. As a secondary objective, we analyzed the evolution according to the type of mRNA vaccine administered. Method(s): From April to October 2021, KT recipients with COVID-19, included in the COVID-19 registry of the Spanish Society of Nephrology, were analyzed. Data regarding vaccination status and type of vaccine were collected and outcomes of unvaccinated or partially vaccinated patients were compared with fully vaccinated patients. Result(s): Clinical picture was similar and survival analysis showed no differences between groups: 21.7% of fully vaccinated patients and 20.8% of unvaccinated or partially vaccinated died (p=.776). In multivariable analysis age and pneumonia were independent risk factors for death, while vaccination status was not related to mortality. These results remained similar when we excluded patients with partial vaccination as well as when we analyzed exclusively hospitalized patients. Patients vaccinated with mRNA-1273 (Moderna) (n=213) showed a significantly lower mortality than those who received BNT162b2 (Pfizer-BioNTech) vaccine (n=121) (16.4% vs. 28.8%, p=.002) (HR: 0.52, CI 95% 0.31-0.85, p=.010). Conclusion(s): COVID-19 severity in KT patients has remained high and has not improved despite receiving 2 doses of an mRNA vaccine, but the mRNA-1273 vaccine shows higher clinical effectiveness than BNT162b2 in KT recipients with breakthrough infection, so it could be considered as the first option in these patients.

4.
Annals of Emergency Medicine ; 80(4, Supplement):S103, 2022.
Article in English | ScienceDirect | ID: covidwho-2060361
5.
1st LACCEI International Multi-Conference on Entrepreneurship, Innovation, and Regional Development: Ideas to Overcome and Emerge from the Pandemic Crisis, LEIRD 2021 ; 2021.
Article in Spanish | Scopus | ID: covidwho-2056682

ABSTRACT

This research article describes the importance of the English language as a foreign language within a inquiry, gamification, autonomous learning and digital reading process. The main objective was about developing a digital proposal that would promote the use of technical English applied to the reading plan in some courses of the civil engineering program through a virtual environment, it was based on interactive and digital magazines. They worked about the civil engineering discipline and they were focused on the ESP methodology. It was framed within the reading plan established through the syllabus of the four disciplinary courses. The mandatory quarantine situation generated by Covid-19 made part of the methodological process and fieldwork research. Just because it was 100% virtual. The research was carried out using a correlational quantitative methodological. The intervened sample was 161 students. Talking about the results obtained, it is highlighted that the reading plan proposed from the digital magazines enhanced the level of English to the civil engineering students, it was according to statistical facts used to measure different aspects from the type of research selected. The situation of virtualized education was used to strengthen disciplinary themes about civil engineering program and foreign language skills. © 2021 Latin American and Caribbean Consortium of Engineering Institutions. All rights reserved.

7.
Pediatrics ; 149, 2022.
Article in English | EMBASE | ID: covidwho-2003435

ABSTRACT

Purpose/Objectives: Patients with Limited English proficiency (LEP) are at greater risk for hospital admissions and representations to the emergency department (ED) in comparison to patients with English proficiency (EP). Improved communication with language services has been shown to decrease these health disparities. In our free-standing Children's Hospital yearly ED representation rates for patients with LEP (4.6%) are over 20% higher than for our patients with EP (3.7%). We aimed to decrease the 7-day representation rate for patients with LEP in the emergency department by 20% over 18 months using the Plan Do Study Act (PDSA) method for quality improvement. Design/Methods: Our first cycle was the deployment of video remote interpretation (VRI). Second and third cycles included focused teaching for Faculty, House staff and staff on VRI use. PDSA cycles were interrupted with the unexpected event of Covid-19 and issues obtaining Cerner data. We evaluated outcomes quantitatively based on data from our language service provider and electronic medical record (EMR). We also conducted an electronic survey of Faculty and Staff to evaluate quantitatively over time VRI reception and frequency of obtaining preferred language. Results: LEP representation rates initially increased followed by a decreasing trend with the Covid19 pandemic and opening of an ED observation unit but this trend was not sustained and average representation rates after PDSA cycles increased to 6.1%. EP representation rates overall remained unchanged at 3.7%. Utilization of interpretation carts increased from 0 to >250 total calls made per month over the course of 18 months. The monthly average number of identified patients with LEP decreased after changes were made to the recording system in the EMR. Monthly rates of interpretation carts used for un-identified patients with LEP were found to range from 27% to 78%, signifying significant under identification in the EMR. 75% of ED Faculty and staff reported that they only ask preferred language or offer interpretation services for medical discussions infrequently when patients appear to speak English well but is clearly not their native language. Total ED visit numbers decreased after March of 2020 to 30-50% of expected due to Covid-19 pandemic. Conclusion/Discussion: ED Patients with LEP had an unexpectedly high rate of un-identification in addition to ED faculty and staff reporting not asking preferred language if the patient seems to speak English well. This has likely led to an underestimation of our LEP representation rate and lack of representative change during our PDSA cycles. Without identifying this vulnerable population, we will always be lacking in providing care in the preferred language which is critical for improving outcomes for our patients with LEP. Our next steps are to develop interventions to increase the identification of patients with LEP to provide safe and comprehensive care for this vulnerable population.

8.
Diseases of the Colon and Rectum ; 65(5):118-119, 2022.
Article in English | EMBASE | ID: covidwho-1894130

ABSTRACT

Purpose/Background: Perioperative COVID-19 infection is associated with an increase in morbidity and mortality, in addition to the consequences on surgical pathologies due to delays in diagnosis and treatment. Hypothesis/Aim: The aim of this study it is to describe and evaluate the effects of the pandemic on patients undergoing colorectal cancer surgery in the UC-Christus Healthcare Network. Methods/Interventions: A retrospective observational cross-sectional cohort study was made. It was based on the review of the admissions and surgical protocols of patients operated due to colon and rectal cancer diagnosis between 03/18/2019 - 03/17/2021 in the UC-Christus Healthcare Network. Patients with incomplete records and follow-ups, recurrences, or endoscopic treatments were excluded. The results of patients who were operated before the sanitary restrictions were compared with those who were operated afterwards (03/18/2020). The variables of sex, age, date of surgery, procedure, approach, tumor location, TNM, biopsy, pathological stage, presence of neoadjuvant and/or adjuvant, cause of mortality, emergency admission, and ostomy requirement were recorded in a database. The descriptive and analytic statistics of the results were analyzed using the Microsoft SPSS-Statistics21 program. Proportions were compared with the Chi2 test and Fisher's exact test in variables whose frequency was less than 5. Results/Outcome(s): One hundred seven records were included in the first period (79 colon and 28 rectal tumors) and 134 in the second (100 colon and 34 rectal tumors), with no significant differences between the number of patients nor the distribution by sex in both periods. In the colon tumors group, there were no significant differences between the groups of patients with early-stage (17), locally advanced (118), and metastatic (44) tumors between both periods. Nineteen patients (10.6%) underwent emergency surgery, 36 patients (20.1%) required an ostomy to be performed without significant differences in both periods. At the rectum tumor group, there were no significant differences concerning sex, nor pathological stage, where 17 (26.9%) were in the initial stages, 29 (46%) locally advanced, and 17 (26.9%) were metastatic. The laparoscopic approach was preferred in all tumor groups, requiring conversion in 6 (4.65%) colon tumor and 1 (2.17%) rectal tumor cases. No mortalities were recorded 30, 60, nor 90 days after Limitations: Among the limitations of our study is a selection bias, since it was carried out only in one institution, so the results obtained here are not necessarily extrapolated to the general population. Conclusions/Discussion: In patients operated in the oncology program of the Healthcare Network, there were no significant differences regarding the number of operated patients, their pathological stage, mortality, or approach in the compared periods.

11.
Journal of Sexual Medicine ; 19(4):S89-S89, 2022.
Article in English | Web of Science | ID: covidwho-1849151
12.
Siglo Cero ; - (1):163-182, 2021.
Article in Spanish | Scopus | ID: covidwho-1847762

ABSTRACT

The objective of the study was to investigate whether the teaching practices developed in times of compulsory preventive social isolation in Argentina favor the inclusion, learning and autonomy of students with intellectual disabilities, in the opinion of their professionals supporting inclusion and of their families. An exploratory-descriptive design was carried out, with an intentional sampling. A semi-structured questionnaire was applied to 75 inclusion support professionals and 40 families of children and adolescents with intellectual disabilities included in common schools of state and private management, in Córdoba (mainly) and other Argentine provinces. As a result, the State has not been able to guarantee access of its students with intellectual disabilities, under equal conditions, to emergency remote teaching not only for not ensuring the necessary technology and connectivity. The teaching task focused on homogeneous planning, leaving the curricular adaptations to the external support professionals, direct attention to the student with disabilities, and counseling for families. The teacher"s relationship with the student with intellectual disability shows poor communication, listening and a positive relationship. Consequently, many students have not reached the proposed learning objectives nor the expected autonomy. © 2021 University of Salamanca. All rights reserved.

13.
Rev Esp Quimioter ; 35 Suppl 1: 67-72, 2022 Apr.
Article in English | MEDLINE | ID: covidwho-1836622

ABSTRACT

The SARS-CoV-2 (COVID-19) pandemic represents the infection with the highest lethality, but also the one that has caused the most sequelae and multi-organ consequences, especially respiratory, in the last century. Several actions have been required in the field of respiratory and intensive care medicine to reduce mortality and chronicity. The consequences of COVID-19 are multiple and encompass different physical, emotional, organizing, and economic aspects, which will require a multidisciplinary, transversal, and collaborative approach. This review includes the observations and results of published retrospective and prospective studies on post-COVID19 respiratory sequelae, especially after severe pneumonia with associated adult respiratory distress syndrome (ARDS).


Subject(s)
COVID-19 , Respiratory Distress Syndrome , Adult , COVID-19/complications , Humans , Prospective Studies , Respiratory Distress Syndrome/etiology , Respiratory Distress Syndrome/therapy , Retrospective Studies , SARS-CoV-2
16.
Journal of Sexual Medicine ; 19(4):S89-S89, 2022.
Article in English | Academic Search Complete | ID: covidwho-1788151

ABSTRACT

Coronavirus Disease 2019 (COVID-19) is an emerging infectious disease caused by a novel coronavirus (SARS-CoV-2) which has been found to cause systemic inflammation in some patients. Many possible long-term sequelae of COVID-19 have yet to be identified. Since endothelial cells have both angiotensin-converting enzyme 2 (ACE2) and transmembrane protease, serine 2 (TMPRSS2) receptors, and SARS-CoV-2 requires both receptors for cell entry, we hypothesized that widespread endothelial damage caused by COVID-19 infection leads to Peyronie's disease (PD). New-onset PD after resolved COVID-19 infection was evaluated. This study was performed after Institutional Review Board approval. After comprehensive history and physical exam, penile duplex was used to evaluate blood flow and characterize any plaques. International Index of Erectile Function (IIEF) was used to evaluate erectile function. Brachial artery flow-mediated dilation (FMD) and endothelial progenitor cell – colony forming units (EPC-CFU) assays were utilized as measures of endothelial function. Available data from two separate control groups were used for comparisons: "No PD" contains subjects with a history of cardiovascular disease and normal erectile function according to IIEF-EF score (n=27). This group was selected to serve as a negative control with endothelial dysfunction. A second control group "Healthy Controls" was selected as a positive control containing male participants who were free from any significant cardiovascular medical history (n=9). New-onset PD after resolution of COVID-19 infection was identified in one patient. The penile duplex with erectogenic agents demonstrated normal vascular flow with presence of calcified plaques. The PD group median EPC-CFU levels were 0 as compared to 1.60 in the no PD (negative control) group and 20.00 in healthy (positive) controls. Similarly, median FMD% was impaired in the PD group (2.35%) and no PD group (3.88%) as compared to healthy controls (7.75%). These findings reveal a novel mechanism for PD after resolution of COVID-19 infection. These findings have significant clinical and biological implications for males with PD and should be considered as a possible sequela of COVID-19 infection. Any of the authors act as a consultant, employee or shareholder of an industry for: Acerus Pharmaceuticals, Boston Scientific, Coloplast, Endo Pharmaceuticals, Empower Pharmacy, Nestle Health, Olympus [ FROM AUTHOR] Copyright of Journal of Sexual Medicine is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

17.
Open Forum Infectious Diseases ; 8(SUPPL 1):S380, 2021.
Article in English | EMBASE | ID: covidwho-1746442

ABSTRACT

Background. Mexico is one of the top five countries with a higher mortality rate of hospitalized patients of 30.1%. Since COVID-19 has been associated with immune dysregulation and hyper inflammation, JAK-12 inhibitors have been tested to reduce IL6 production. Studies have shown improvements when using ruxolitinib (rxb) in severely hospitalized patients with COVID-19. These have included patients in combination with corticosteroids such as dexamethasone (dxm). This work aims to test the response of hospitalized patients with severe or critical COVID-19 treated with rxb with or without dxm. Methods. An experimental, open, prospective study in a single third-level hospital in Mexico was performed. The primary outcome was favorable clinical response defined as withdrawal or decline of supplementary oxygen. Secondary outcomes such as mean hospital stay, improvement in systemic inflammatory response parameters, and mortality were also evaluated. Statistical differences for baseline and final measure and the use and not use of dxm were estimated. The study included adults with SARSCoV-2 infection confirmed with polymerase chain reaction, radiological pneumonia, and oxygen saturation less than 90%. Rxb was administered 5mg/12hrs/15days, IV dxm 6mg/day/10days. Results. The final sample was 108 adults with complete information and informed consent. Sixty-two patients (57%) received only rxb. There were no differences between groups for any parameter at the beginning of treatment, and all patients were receiving supplemental oxygen. After 28-day follow-up, 70% reduce supplemental oxygen requirement (74% rxb and 71% rxb+dxm;p=0.628), 18% remained, and 2% increases support (1% with rxb, and 5% rxb+dxm;p< 0.001);87% of patients were discharged (89% rxb and 85% rxb+dxm;p=0.603). In both groups, there was a significant reduction of CRP, LDH, and Ferritin on day 15. The mortality rate was 9% (no difference in groups;p=0.453), and a higher proportion died for Pseudomonas aeruginosa superinfection in the rxb+dxm group (p< 0.001). Conclusion. The use of rxb could be considered as a treatment helping clinical improvement in hospitalized patients with severe COVID-19. Combination with dxm apparently did not add clinical benefits. It should be further evaluated.

20.
Revista espanola de salud publica ; 95, 2021.
Article in Spanish | Scopus | ID: covidwho-1628173

ABSTRACT

The Covid-19 pandemic and the measures adopted for its control have had a significant impact, both in and at health, social and personal levels. The Spanish Observatory of Drugs and Addictions designed a survey to study the change in the pattern of consumption of psychoactive substances and other behaviors with addictive potential, such as the use of the Internet and gambling with money, in the Spanish population during the pandemic COVID-19. A random sample of 7,886 people aged 15 to 64 was interviewed by a telephone survey. The results show a decrease in the consumption of alcohol, tobacco and cannabis and non-internet gambling, along with an increase in the use of non-prescription hypnosedatives and the number of hours spent using the internet for recreational purposes, while online gambling remained unchanged. This overall decline in use occurs in a context of reduced access to illicit drugs, a consequence of the control measures adopted in the COVID-19 pandemic in Spain. The control measures also affected leisure environments, and this has possibly contributed to the changes observed, especially in heavy episodic alcohol consumption among young people, showing the impact of environmental prevention in tackling this problem. La pandemia por Covid-19 y las medidas adoptadas para su control han supuesto un importante impacto, tanto sanitario como social y personal, a todos los niveles. El Observatorio Español de las Drogas y las Adicciones diseñó una encuesta para estudiar el cambio en el patrón de consumo de sustancias psicoactivas y otras conductas con potencial adictivo, como el uso de internet y el juego con dinero, en la población española durante la pandemia por Covid-19. Se realizó una encuesta telefónica sobre una muestra de 7.886 personas de 15 a 64 años representativa a nivel nacional. Los resultados muestran un descenso del consumo de alcohol, tabaco, cannabis y juego con dinero presencial, que contrasta con un aumento del consumo de hipnosedantes sin receta y del número de horas dedicado al uso de internet por diversión, mientras que el juego online permaneció sin cambios. El descenso generalizado de los consumos se ha producido en un contexto de diminución del acceso a las drogas ilegales, consecuencia de las medidas adoptadas para el control de la pandemia por COVID-19. Estas afectaron a los entornos de ocio lo que, posiblemente, ha contribuido a los cambios observados, en especial en los consumos intensivos de alcohol en jóvenes, sugiriendo la relevancia de las medidas de prevención ambiental en el abordaje de este problema.

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