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World journal of virology ; 11(3):144-149, 2022.
Article in English | EuropePMC | ID: covidwho-1877203


BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants are currently a new hazard. Since the first appearance of classical SARS-CoV-2 in late 2019, pathogen genetic alterations have continued to occur, and some new hazardous forms have already emerged. The underlying pathophysiological process leading to clinical issue is molecular change caused by genetic mutation. AIM To determine the change in the interaction between receptor binding domain of omicron variant SARS-CoV-2 and the angiotensin-converting enzyme 2 (ACE2). METHODS The researchers investigated how alterations in the binding area of the SARS receptor CoV2 interacted electrostatically with the ACE2 receptor. In this report, three important coronavirus disease 2019 variants, beta, delta, and omicron, were investigated. RESULTS According to this study, there was a change of electrostatic interactions between the receptor binding domain of SARS-CoV-2 with the ACE2 receptor due to each studied variant. The most change was detected in omicron variant followed by delta variant and beta variant. CONCLUSION Our results may support the clinical finding that the omicron variant is more transmissible than the wild type and other variants.

HeartRhythm case reports ; 2022.
Article in English | EuropePMC | ID: covidwho-1877202
Cardiology ; : 1-1, 2022.
Article in English | EuropePMC | ID: covidwho-1824250
World Neurosurgery ; 158:344-344, 2022.
Article in English | Academic Search Complete | ID: covidwho-1683670
Medicina clinica ; 2022.
Article in Spanish | EuropePMC | ID: covidwho-1661307
The Egyptian journal of neurology, psychiatry and neurosurgery ; 58(1), 2022.
Article in English | EuropePMC | ID: covidwho-1615287


COVID-19 is the present global public health problem. This respiratory viral infection can manifest atypical presentation including neurological presentations. An important neurological problem in COVID-19 is neurovascular thrombosis. The basic pathogenesis of thrombosis in neurological system is explainable by the basic principle of thrombohemostasis. A hypercoagulability is a possible problem seen in some COVID-19 cases. In this brief review, the authors summarize venous and arterial thrombosis of neurovascular system as a complication of COVID-19. The updated pathophysiology of COVID-associated blood coagulation disorder is discussed. In addition, consideration regarding new COVID-19 vaccine related thrombotic adverse event is also raised.

Enfermedades infecciosas y microbiologia clinica (English ed.) ; 40(1):48-48, 2022.
Article in English | EuropePMC | ID: covidwho-1602311
Arthritis Care & Research ; n/a(n/a), 2021.
Article in English | Wiley | ID: covidwho-1589266
Atencion primaria ; 54(3):102255-102255, 2021.
Article in English | EuropePMC | ID: covidwho-1564576
Erciyes tıp dergisi = Erciyes Medical Journal ; 43(4):410, 2021.
Article in English | ProQuest Central | ID: covidwho-1289293