ABSTRACT
A study of lipid metabolism was carried out in 161 residents of Yakutsk aged 20 to 72 years who had a disease with a new coronavirus infection SARS-CoV-2 from 3 to 12 months ago. The aim of the work was to assess the lipid profile after recovery from COVID-19, depending on the post-COVID period and severity of the disease, as well as the level of total cholesterol in inpatients at admission, discharge and in the post-COVID period. According to the results of the study, when infected with the SARS-CoV-2 virus, lipid metabolism is disturbed: in the acute period of infection, the level of total cholesterol decreases, in the post-COVID period, its level significantly increases. The most pronounced shift in the lipid profile towards atherogenicity occurs in patients who recovered from COVID-19 three months ago due to a decrease in the antiatherogenic fraction of lipids. Dyslipidemia is most pronounced in patients who have had an infection with severe lung damage (50-75%) due to an increase in atherogenic lipid fractions that create a risk of atherosclerosis.
ABSTRACT
We have analyzed the impact of herpes virus infection on the course of a new coronavirus infection (NCVI). Infection of the examined contingent with herpes family viruses reached 95.3-100%. An association of NCVI with herpes simplex viruses 1, 2 types (HSV 1, 2 types) was found, but no correlation was found between the positivity coefficient (CP) of HSV 1, type 2 and the severity of NCVI. This can be explained by the fact that the sampling was carried out in the remote period after the transferred NKVI. Considering that both herpes viruses and the SARS-CoV-2 virus cause multiple organ damage and can aggravate each other, the study of co-infection seems to be very relevant.