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1.
Embase; 2022.
Preprint in English | EMBASE | ID: ppcovidwho-333898

ABSTRACT

The Western mesoregion, the State of Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by the COVID-19 pandemic in early 2021. This study aimed to evaluate the dynamics of the SARS-CoV-2 virus spreading patterns in the SC state through March 2020 to April 2021 using genomic surveillance. During this period, 23 distinct variants, including Beta and Gamma, among which, the Gamma and related lineages were predominant in the second pandemic wave within SC. A regionalization of P.1-like-II in the Western-SC region was observed, concomitant to the increase in cases, mortality, and case fatality rate (CFR) index. This is the first evidence of the regionalization of the SARS-CoV-2 in SC transmission and highlights the importance of tracking variants, dispersion, and impact of SARS-CoV-2 on the public health systems.

2.
Clin J Sport Med ; 32(2): e184-e220, 2022 Mar 01.
Article in English | MEDLINE | ID: covidwho-1758934
3.
Brazilian Journal of Infectious Diseases ; 26, 2022.
Article in Spanish | EMBASE | ID: covidwho-1748191

ABSTRACT

A OMS estabelece como métricas para avaliação da transmissão comunitária da COVID-19 a ocorrência de casos novos, mortes, internações e positividade da testagem sentinela. A testagem sentinela por razões econômicas e logísticas não ocorreu no Brasil e sempre atuamos sob indicadores já ocorridos. Considerando a relevância da transmissão assintomática, sobretudo com a expansão da vacina, e a necessidade de aprimorar a vigilância sobre a circulação viral implementamos um projeto sentinela na cidade de Cubatão na região da Baixada Santista em São Paulo. Realizamos semanalmente, aos sábados, dois testes para cada 1000 habitantes em todas as regiões do município, incluindo as mais socialmente desafiadoras, respeitando as bases e divisões dos setores censitários do IBGE. Aplicamos o TCLE e coletamos um questionário em meio digital com dados demográficos, clínicos e epidemiológicos. Entre 31/07 e 25/09/21 foram realizados 2185 testes (Panbio-AbbottR). Foram identificados 6 casos positivos no período (0,3%). A mediana de idade dos testadas foi de 49 anos, sendo 51,8% do sexo feminino. Em média, ao longo do período de testagem, 51,1% da amostra avaliada havia tomado 2 doses de vacinas dentro do prazo e foi possível avaliar a evolução da cobertura vacinal no período. Na última data de inquérito no período (25/09/2021), 75,59% da amostra estava plenamente vacinada e quase a totalidade com uma dose ao menos. Os resultados de baixa positividade alinham-se com a redução na demanda por consultas em PA por COVID (menos 70%), por internações (menos 97%) e por vagas em UTI (menos 98%) comparando-se os meses entre março (pico) e agosto de 2021. Alinham-se ainda à redução de positividade do RT-PCR entre sintomáticos de 88% para o mesmo período (de 43,6 para 4,9%). Entre 30/08 e 08/09/21 100% das variantes isoladas no município são delta e nenhum dos pacientes teve evolução desfavorável com necessidade de internação. O uso da testagem sentinela mostrou-se uma ferramenta útil no processo da gestão dos leitos e decisões estratégicas da secretaria de saúde, teve excelente aceitação e performance sem nenhuma perda, foi sensível e esteve em linha com os dados compilados pela gestão. Seu uso deve ser realizado como ferramenta útil no monitoramento precoce e antes que desfechos clínicos mais severos estejam concretizados. Por fim, está evidente a performance da vacina como ferramenta essencial na proteção contra formas graves da COVID e na contenção da expansão da variante delta.

4.
16th International Symposium on Operational Research in Slovenia, SOR 2021 ; : 345-350, 2021.
Article in English | Scopus | ID: covidwho-1717354

ABSTRACT

An unprecedented outbreak pandemic caused disruption around the world. It had a strong impact on economic sector. Although, the pandemic accelerated the growth of e-commerce for specific categories as food retailer. As a result, several companies restructured their structures, in terms of IT and operations. During the first confinement, the operations and the website of SONAE MC were not prepared for the increase that existed due to the pandemic, COVID-19, causing disruption in the supply chain and long lead times. In this paper, it is explained how SONAE MC reduced its dependence on refrigerated vehicles, simplifying operations and reducing the costs of transporting products from online orders in vehicles with cargo space able to transport positive cold food and negative cold. It is also explained how innovation has ensured that products continue to be transported with quality and safety to all customers of the SONAE MC Darkstore. The result was the implementation of the proposed solution which may grow technologically once information and equipment are available. © 2021 Samo Drobne – Lidija Zadnik Stirn – Mirjana Kljajić Borštnar – Janez Povh – Janez Žerovnik

10.
Perspectivas Em Dialogo-Revista De Educacao E Sociedade ; 8(18):276-+, 2021.
Article in Portuguese | Web of Science | ID: covidwho-1694995

ABSTRACT

Medicinal plants are important because they are part of the history of humanity. And from this man-nature relationship, traditional knowledge and knowledge were born, from which culture and experiences in the use of medicinal plants are based. In this context, this study aimed to analyze how ethnobotanical knowledge, specifically medicinal plants, has contributed to the health care of some students' families in divergent realities, during this period of the Covid-19 pandemic. Thus, a comparative analysis was carried out between two schools, one school located in the "field", rural area of Madalena, Ceara, Brazil, the EEM Joao dos Santos de Oliveira school and the other school located in the metropolitan region of Fortaleza, in Pacajus, Ceara, Brazil, named EEM Dione Maria Bezerra Pessoa. As for the methodological procedures, the research started with a semi-structured questionnaire with the purpose of collecting and producing data, using quantitative and qualitative approaches. The research subjects were 60 students, 30 from each school. The study revealed that the location and ethnosabers acquired by rural students and in the metropolitan region do not present significant differences, considering the variation in social and cultural interaction.

12.
Embase;
Preprint in English | EMBASE | ID: ppcovidwho-326829

ABSTRACT

Objectives: To investigate whether wearing a cloth facemask could affect physiological and perceptual responses to exercise at distinct exercise intensities in non-trained men and women. Methods: In a crossover design, participants (17 men and 18 women) underwent a progressive square-wave test at four intensities (i. at 80% of the ventilatory anerobic threshold [80%VAT];ii. at VAT;iii. at the respiratory compensation point [RCP];iv. at exercise peak [Peak] to exhaustion), with or without a triple-layered cloth mask (Mask or No-Mask). Several physiological, metabolic and perceptual measures were analyzed. Results: Mask reduced inspiratory capacity at all exercise intensities vs. No-Mask (p<0.0001), irrespective of sex. Mask reduced respiratory frequency vs. No-Mask (p=0.001) at Peak (-8.3 breaths·min-1;CI: -5.8, -10.8), RCP (-6.9 breaths·min-1;CI: -4.6, -9.2) and VAT (-6.5 breaths·min-1;CI: -4.1, -8.8), but not at Baseline or at 80%VAT. Mask also reduced tidal volume (p<0.0001) at both RCP (-0.5L;CI: -0.3, -0.6) and Peak (-0.8L;CI: -0.6, -0.9), but not at Baseline, 80%VAT or VAT. Shallow breathing index was increased with Mask at Peak compared to No-Mask (11.3;CI: 7.5, 15.1), but not at any other intensities. Mask did not change heart rate, lactate, ratings of perceived exertion, blood pressure or oxygen saturation. Conclusions: Wearing a cloth facemask during exercise at moderate to heavy intensities is unlikely to incur significant respiratory or cardiovascular changes, irrespective of sex. These data can inform new exercise recommendations for health during the COVID-19 pandemic and debunk unfounded allegations of harmful effects of masks during exercise.

13.
J Hosp Infect ; 123: 23-26, 2022 Feb 14.
Article in English | MEDLINE | ID: covidwho-1683310

ABSTRACT

BACKGROUND: Although the risk of SARS-CoV-2 transmission within hospitals has been well recognized, there is a paucity of data on its occurrence. Our aim was to report the incidence of hospital-acquired (HA) COVID-19 at Brazilian hospitals. METHODS: We investigated the incidence of HA COVID-19 in Brazilian hospitals using data from a national surveillance system, from August 2020 through September 2021. Definitions of HA COVID-19 were: (1) symptom onset >14 days after hospital admission plus a positive SARS-CoV-2 RNA or antigen test; (2) symptom onset on days 8-14 after admission, plus a positive SARS-CoV-2 RNA or antigen test positive, plus documented high-risk exposure. We performed descriptive analyses and reported HA COVID-19 rates using pooled mean and percentile distribution. RESULTS: A total of 48,634 cases of HA COVID-19 were reported from 1428 hospitals. Incidence ranged from 0.16/1000 patient-days at neonatal intensive care units (ICUs) to 5.8/1000 patient-days at adult ICUs. The highest incidence of HA COVID-19 was during the months March to July 2021, similar to that which was observed for community-acquired COVID-19. CONCLUSIONS: This report provides a national view of the burden of HA COVID-19. The highest incidence of HA COVID-19 similar that which was observed for community-acquired COVID-19. We believe that this reflects the difficulty of implementing preventive measures. Further studies evaluating risk factors for the hospital transmission of SARS-Cov-2 should clarify strategies to minimize the risk of HA COVID-19 and may be applicable to other respiratory diseases. Furthermore, the implementation of a national system to evaluate HA COVID-19 has the potential to shine a light on this problem and lead to interventions in each hospital.

14.
Brazilian Journalism Research ; 17(3):562-595, 2021.
Article in English | Scopus | ID: covidwho-1675557

ABSTRACT

This paper begins with a discussion of the concept of populism in order to analyze how Jair Bolsonaro's criticisms of the press circulated on the social network Twitter at a time when Brazil had recorded the highest number of covidrelated deaths, in the first week of March 2021. This paper presupposes that the president's support network incorporated the populist binary rhetoric of "us" against a "corrupt elite" which is responsible for conspiring and amplifying the effects of the health crisis in the country. As a methodology, we opted for a mixed proposal based on content analysis and analysis of social networks. As a result, we found that the tweets from Bolsonaro supporters claim that the press is corrupt, and manipulates and harasses the president in its coverage of the pandemic. © 2021 Associacao Brasileira de Pesquisadores de Jornalismo. All rights reserved.

15.
3rd International Conference on Quantitative Ethnography, ICQE 2021 ; 1522 CCIS:253-267, 2022.
Article in English | Scopus | ID: covidwho-1669745

ABSTRACT

The early stages of the COVID-19 pandemic intensified the role of healthcare workers in hospitals. This study examines how healthcare workers reflected on their in-hospital experiences in the early stages of the pandemic in North America. Audio diary entries from The Nocturnist podcast recorded from March – June 2020 were analyzed using epistemic network analysis (ENA) and heat map models. Overall, there was a shift from responding to immediate needs in March 2020 (such as Anger with Policies and Fear with Resource Availability) to deeper reflections in May-June 2020, more focused on Psychosocial Support and Purpose and more complex emotions involving Sadness and Compassion. Uncertainty was a prominent emotion throughout the May – June 2020 period. These results help document the complexity of reflections early in the pandemic, while informing ways to better support health care workers in future crisis. © 2022, Springer Nature Switzerland AG.

17.
Confins-Revue Franco-Bresilienne De Geographie-Revista Franco-Brasileira De Geografia ; 52:17, 2021.
Article in Portuguese | Web of Science | ID: covidwho-1576601

ABSTRACT

After almost a year, the covid-19 pandemic did not prove to be as democratic as was announced: the urban peripheries, more socially vulnerable, proved to be privileged areas of contamination. Thus, the objective of this article is to analyze the impacts of the covid-19 in the peripheries of the Metropolitan Region of Rio de Janeiro, highlighting the capital and the municipalities that make up the Baixada Fluminense. Presenting a conceptual debate on social vulnerability and dialoguing with the field of public health, maps and tables were produced, based on official case and death data from the State of Rio de Janeiro Health Department, by municipality, and estimated population in 2020, from IBGE Cidades, to calculate the Prevalence, Mortality and Lethality Rates, to seek an analytical understanding of the diffusion of covid-19 in the peripheral territories of Rio de Janeiro. Despite the obstacles to underreporting, the results made it possible to identify a similar spatial behavior between groups of municipalities, highlighting the importance of social vulnerability as one of the most relevant elements of the spread of covid-19.

18.
European Heart Journal ; 42(SUPPL 1):1316, 2021.
Article in English | EMBASE | ID: covidwho-1554450

ABSTRACT

Introduction: Recently during the COVID-19 pandemic there was a general belief in a reduction of hospital admissions due to non-infectious causes, namely cardiovascular diseases. Objectives: To evaluate the impact of the pandemic in the admissions by ST elevation acute myocardial infarction (STEMI), during the first pandemic wave. Methods: Multicentric and retrospective analysis of consecutive patients presenting in two Portuguese hospital centers with STEMI in two sequential periods - P1 (1st March to 30th April) and P2 (1st May to 30th June). A comparison of patient's clinical and hospital outcomes data was performed between the year 2020 and 2017 to 2019 for both periods. Results: A total of 347 consecutive STEMI patients were included in this study. The patient's baseline characteristics and cardiovascular risk factors were similar across the considered periods. During P1 of 2020, in comparison with previous years, a reduction in the number of STEMI patients was observed (26.0±4.2 vs 16.5±4.9 cases per month;p=0.033), contrary to what was observed during P2 (19.5±0.7 vs 20.5±0.7 cases per month;p=0.500). Percutaneous coronary interventions in the setting of failed thrombolysis were more frequent (1.9% vs 9.1%;p=0.033). A global trend in longer delays in time-key bundles of STEMI care was noted, namely pain to first medical contact, door to needle, door to wire crossing and symptoms to wire crossing times, however without statistical significance. Mortality rate was six-fold higher during P1 comparing to previous years (1.9% vs 12.1%;p=0.005), and also an increase in the number of mechanical complications (0.0% vs 3.0%;p=0.029) was observed. Conclusions: During the first COVID-19 pandemic wave there were fewer patients presenting with STEMI at catheterization laboratory for coronary angioplasty. These patients presented more mechanical complications and higher mortality rates.

19.
European Heart Journal ; 42(SUPPL 1):3129, 2021.
Article in English | EMBASE | ID: covidwho-1554360

ABSTRACT

Introduction: Fast and efficient assessment of prognosis of coronavirus disease 19 (COVID-19) is needed to optimize the allocation of health care and human resources, to empower early identification and intervention of patients at higher risk of poor outcome. A proper assessment tool may guide decision making, to develop an appropriate plan of care for each patient. Although different scores have been proposed, the majority of them are limited due to high risk of bias, and there is a lack of reliable prognostic prediction models. Purpose: To develop and validate an easy applicable rapid scoring system that employs routinely available clinical and laboratory data at hospital presentation, to predict in-hospital mortality in patients with COVID-19, able to discriminate high vs non-high risk patients. Additionally, we aimed to compare this score with other existing ones. Method: Cohort study, conducted in 36 Brazilian hospitals in 17 cities. Consecutive symptomatic patients (≥18 years old) with laboratory confirmed COVID-19 admitted to participating hospitals. Primary outcome was in-hospital mortality. Logistic regression analysis was performed to develop a prediction model for in-hospital mortality, based on the 3978 patients that were admitted between March-July, 2020. The model was then validated in the 1054 patients admitted during August-September, as well as in an external cohort of 474 Spanish patients. Results: Median (25th-75th percentile) age of the model-derivation cohort was 60 (48-72) years, 53.8% were men, in-hospital mortality was 20.3%. The validation cohorts had similar age distribution and in-hospital mortality. From 20 potential predictors, seven significant variables were included in the in-hospital mortality risk score: age, blood urea nitrogen, number of comorbidities, C-reactive protein, SpO2/FiO2 ratio, platelet count and heart rate. The model had high discriminatory value (AUROC 0.844, 95% CI 0.829 to 0.859), which was confirmed in the Brazilian (0.859) and Spanish (0.899) validation cohorts. Our ABC2-SPH score showed good calibration in both Brazilian cohorts, but, in the Spanish cohort, mortality was somewhat underestimated in patients with very high (>25%) risk. The ABC2- SPH score is implemented in a freely available online risk calculator. Conclusions: We designed and validated an easy-to-use rapid scoring system based on characteristics of COVID-19 patients commonly available at hospital presentation, for early stratification for in-hospital mortality risk of patients with COVID-19.

20.
Revista Cientifica Multidisciplinar RECIMA21 ; 2(8), 2021.
Article in Portuguese | CAB s | ID: covidwho-1548011

ABSTRACT

With the pandemic emergence of the SARS-COV-2 in 2019, many doubts and uncertainties arose about the COVID-19 disease, many of them due to the thousands of fake-News, lack of information, little scientific research to prove the unfolding of what actually it would happen, from the symptoms, the forms of contagion, how each organism would react to the virus, about the effectiveness of masks and social isolation, but mainly about the treatments against the new coronavirus. With all these doubts, some measures were taken to try to alleviate and resolve the situation;the so-called "Kit-Covid" (containing medicines, among them antibiotics) and currently not recommended by the Ministry of Health, was one of the controversial measures that took place in Brazil. The recommendation to use drugs without scientifically proven efficacy against the symptoms of COVID-19 caused sales of antimicrobial drugs to double in different parts of the country, including the city of Nanuque, MG, as demonstrated in this study. This increase in the use of antibiotics is worrying, as it increases the probability of cases of microbial resistance, transforming common bacteria into possible superbugs, making it necessary to use increasingly potent antibiotics.

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