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1.
American Journal of Respiratory and Critical Care Medicine ; 205:1, 2022.
Article in English | English Web of Science | ID: covidwho-1879957
2.
Revista Espanola de Salud Publica ; 94(e202011148), 2020.
Article in English | GIM | ID: covidwho-1871410

ABSTRACT

The COVID-19 respiratory manifestations go from mild symptoms similar to those of a common cold to severe pneumonia with respiratory distress syndrome, septic shock and multiorgan failure. The disease is caused by the SARS-CoV-2 virus, whose transmission mechanism most relevant to dentistry is through respiratory droplets and possibly also aerosols, as well as direct contact with mucous membranes of the nose, mouth or eye via contaminated hands or objects. The professionals of the dental health units have a high risk exposure since they work at short distances (less than 1 m from the head of the patient) in the oral cavity, where a maximal expression of possible cell receptors for the virus has been reported. Also, most procedures in the dental cabinet imply aerosol generation. Cross-infection is possible during dental care, not only with diagnosed COVID-19-positive patients but also with patients who remain undetected due to asymptomatic or presymptomatic disease. For all these reasons, dental care in the primary health setting has had to change in order to adapt to the pandemic. The changes affect both the appointment scheduling and the care itself and imply the establishment of general and specific barrier protections as well as measures related to ventilation, cleaning, disinfection and sterilization, reinforced with additional infection prevention and control measures. This article summarizes.

3.
Veterinaria e Zootecnia ; 29, 2022.
Article in Portuguese | EMBASE | ID: covidwho-1863692

ABSTRACT

By the end of 2019, a new coronavirus was identified in China, in patients with severe pneumonia. Since its discovery, the SARS-CoV-2 has quickly spread thoroughout the world. This literature review was conducted to define the role of dogs and cats in the epidemiology of SARS-CoV-2. The coronavirus belongs to the Coronaviridae family, Betacoronavirus genera, is the causative agent of the human COVID-19 and shows spike glycotproteins which allow the virus to enter in the host cell through the binding the spike protein with the receptors of the angiotensin-converting enzyme type 2. There is no reports that companion animals are a source of infection for human beings, however, evidences show that infected humans can transmit viral particles to the animals in a natural way. Infected animals may show mild and self-limiting clinical signs. Thus, dogs and cats can acquire SARS-CoV-2 from their tutors and may transmit to other animals, but not to humans and that is important the understanding about the susceptibility of dogs and cats due their close contact with human beings.

4.
Hematology, Transfusion and Cell Therapy ; 43:S366, 2021.
Article in Portuguese | EMBASE | ID: covidwho-1859658

ABSTRACT

Objetivos: O presente estudo tem como objetivo relatar a experiência dos autores na utilização de aplicativo de mensagens instantâneas, como ferramenta para a pesquisa de satisfação dos clientes (PSC), no HEMOSC. O estudo foi fundamental para avaliar a possibilidade da implantação do novo método de comunicação com os clientes, devido à necessidade de adaptação frente a pandemia SARS-CoV-2. Materiais e métodos: Este relato foi idealizado por meio do redesenho dos moldes da pesquisa de satisfação dos clientes, com a implantação do uso de aplicativo de mensagens instantâneas no ano de 2020, bem como, manter os requisitos legais da Portaria de Consolidação n° 5 de 28 de setembro de 2017, as normativas da ISSO 9001:2015 e aos padrões da AABB, no que tange a comunicação e os instrumentos de tratativas das manifestações dos clientes (doadores e pacientes). A proposta foi idealizada pela Coordenadoria de Planejamento e Qualidade (CPQ), aprovada pela direção e executada pelos responsáveis do processo na hemorrede. Caminho metodológico: 1) Definição do fluxo: encaminhamento da pesquisa, retorno das manifestações e registro das informações necessárias para o relatório final;2) Desenvolvimento do material – folder on line, para envio da pesquisa aos doadores e pacientes e agradecimento em caso de elogios;3) Elaboração de planilha de registro das informações, recebidas da pesquisa aplicada por meio da ferramenta;4) Validação, padronização e treinamento do processo;5) Aquisição e distribuição de aparelhos celulares, provenientes da doação da Receita Federal, por meio de projetos da instituição;6) Download do aplicativo e implantação do método. Resultados: De acordo com o levantamento de dados, foi possível constatar considerável acréscimo de participações na pesquisa. Verificou-se que de Maio a Dezembro de 2019 ocorreram 6.674 manifestações de clientes (doadores e pacientes). Já no ano de 2020, após implantação da ferramenta, comparado a este mesmo período, o total foi de 12.357, representando 85% no aumento de manifestações, o que demonstra a adesão dos colaboradores e clientes ao método utilizado. Discussão: Durante a implantação do aplicativo os outros canais de comunicação, como: formulário físico, site, ouvidoria e redes sociais foram mantidos, entretanto, o maior número de participações está relacionado ao novo método. O índice de satisfação se manteve acima de 97%, sendo possível observar mais proximidade entre instituição e seus clientes, o que evidencia a eficácia do método utilizado. Conclusão: Embora com todas as dificuldades enfrentadas e as alterações realizadas devido a pandemia, a implantação do aplicativo demonstrou excelentes resultados e reafirmou a importância da busca contínua das instituições em promover a qualidade dos seus serviços, independente do cenário atual. O método possibilitou maior interação entre os clientes e a instituição, agregando mais uma ferramenta para identificar as possíveis melhorias nos processos e ainda, afirmar o alto índice de satisfação dos clientes, quanto aos serviços de saúde prestados no HEMOSC.

5.
Movimento-Porto Alegre ; 28:17, 2022.
Article in English | Web of Science | ID: covidwho-1856560

ABSTRACT

Literature has focused on the co-evolutionary understanding between technology and education, highlighting the teacher as a key player in this process. The objective of the text is to problematize the pedagogical experience of a Physical Education teacher from the state education network during the Covid-19 pandemic, under the lens of neotechnicism and emerging literacies. A qualitative methodology was adopted based on narrative studies, pedagogical cases and their contributions to teacher training. As a result, it was noticed the feeling of incompetence to deal with digital platforms, the support of a peer collaboration network, the urgency of "how to use technological tools" and, in the background, "what to teach". Finally, it is considered that thinking about remote Physical Education teaching in the pandemic is more than thinking about technology, but rather it is reflecting on how the teacher is formed by experience and the possibilities of modifying the perception of Physical Education classes in this context.

6.
Quimica Nova ; : 7, 2022.
Article in Spanish | Web of Science | ID: covidwho-1856517

ABSTRACT

DIAGNOSTIC TESTS FOR SARS-COV-2: A CRITICAL REFLECTION. The new coronavirus, called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), was discovered in late December 2019 after cases were reported in the city of Wuhan, China. In January 2020, the World Health Organization (WHO) officially declared the Coronavirus Disease 2019 (COVID-19) as a pandemic, which has an official record of around 500 million cases and more than 6.0 million deaths in worldwide. An important factor in controlling the pandemic is the development of more effective and efficient diagnostic tests. In this context, this review has as its main proposal to discuss the effective differences between the possible diagnostic tests, the implications of molecular and serological methods available on the market and the analytical and clinical parameters involved in the development and application of these methods.

7.
Revista De Direito Da Cidade-City Law ; 14(1):494-516, 2022.
Article in Spanish | Web of Science | ID: covidwho-1856353

ABSTRACT

For the characteristics and strengths related to resilience to emerge, both risk and protective factors must be present that help to achieve a positive result or reduce or avoid a negative result. The study of resilience has generated great interest for scientists in recent decades, understanding that resilience is a universal quality that has always existed, reflecting the ways in which people and societies cope with adversity. The purpose of this article is to integrate Development, Governance and Resilience, conceiving it as the fundamental capacity that governments must develop to address, adapt and overcome the new challenges of chaos. Methodologically, the work is documentary and has an exploratory scope. Government resilience appears as a concept that surpasses the previous theoretical proposals on State reform because its realization demands, more than a modification of instruments, organizational forms or rules, a full institutional change.

8.
Handbook of Research on Reinventing Economies and Organizations Following a Global Health Crisis ; : 386-408, 2021.
Article in English | Scopus | ID: covidwho-1810438

ABSTRACT

The COVID-19 pandemic has brought a global downturn in economic activity, with new social and economic conditions. For executive secretariat professionals, the pandemic has significantly contributed to change the way they operate, their tasks, activity, and importance in the organizations. The present investigation intends to understand the perception of the executive secretarial professionals of companies about the exercise of their profession, before and during the COVID-19 pandemic. Results obtained show that there have been significant changes in the new conditions and requirements inherent to the exercise of the profession, in terms of their competencies and responsibilities, as well in the implementation of new forms of work. © 2021, IGI Global.

9.
Data Science for COVID-19 Volume 1: Computational Perspectives ; : 1-24, 2021.
Article in English | Scopus | ID: covidwho-1787938

ABSTRACT

Following the World Health Organization proclaims a pandemic due to a disease that originated in China and advances rapidly across the globe, studies to predict the behavior of epidemics have become increasingly popular, mainly related to COVID-19. The critical point of these studies is to discuss the disease’s behavior and the progression of the virus’s natural course. However, the prediction of the actual number of infected people has proved to be a difficult task, due to a wide range of factors, such as mass testing, social isolation, underreporting of cases, among others. Therefore, the objective of this work is to understand the behavior of COVID-19 in the state of Ceará to forecast the total number of infected people and to aid in government decisions to control the outbreak of the virus and minimize social impacts and economics caused by the pandemic. So, to understand the behavior of COVID-19, this work discusses some forecast techniques using machine learning, logistic regression, filters, and epidemiologic models. Also, this work brings a new approach to the problem, bringing together data from Ceará with those from China, generating a hybrid dataset, and providing promising results. Finally, this work still compares the different approaches and techniques presented, opening opportunities for future discussions on the topic. The study obtains predictions with score of 0.99 to short-term predictions and 0.93 to long-term predictions. © 2021 Elsevier Inc. All rights reserved.

10.
Revista Juridica ; 3(65):286-308, 2021.
Article in Portuguese | Scopus | ID: covidwho-1786578

ABSTRACT

Objective: This article aims to demonstrate that the response to the pandemic does not deviate from the response to the climate crisis, mobility plans need only minor changes in the schedule of actions. Method: This study uses the empirical and deductive method, through a qualitative approach;the procedure is a bibliographic and legislative research, through the review of studies and scientific articles and legislation, as well as studies and public policies extracted from the official pages of Salvador, Bahia. In order to clarify the link between mitigation and adaptation to the climate crisis, response to the impacts of the pandemic and urban planning of the municipality. Results: The inventory of GEE of Salvador is analyzed, and it is verified that transportation is their major emitter. The Salvador Sustainable Urban Mobility Plan (PlanMob) is examined, and it is noted that it provided for measures to adapt and mitigate the climate crisis, but not to the pandemic crisis. When reviewing scientific articles, it is found that the pandemic decreased the use of public transportation and increased the use of individual transportation. Conclusions: It is recommended that the urban mobility plans of the municipalities be adapted to prevent the dissemination of COVID-19, providing for an expansion of bike paths, boardwalk and escalators. © 2021, Centro Universitario Curitiba - UNICURITIBA. All rights reserved.

11.
Humanidades & Inovacao ; 8(63):55-65, 2021.
Article in Portuguese | Web of Science | ID: covidwho-1766750

ABSTRACT

Distance work in school institutions are now a reality in Brasil since the Covid-19 pandemic announcement made by WHO. Certainly, all subjects went from in-class courses to online courses. However, several questions beyond the formal teaching curricula need to now be addressed online, specifically themes related to bodies. We are caught in a pandemic that collects dead bodies, sometimes due to the effects of the virus, sometimes due to its side effects, such as domestic violence. We aim, through a decolonial biogeographic frontier perspective of discussion - to understand how women/girls and their bodies have been suffering from this atypical period. Have we prepared our students to be able to access knowledge and also interpret the social effects that social isolation has brought to each one of us? How have female bodies been marked, what are the effects of silencing in the face of emerging issues such as nd violence?

12.
21st IEEE International Conference on Bioinformatics and Bioengineering (IEEE BIBE) ; 2021.
Article in English | Web of Science | ID: covidwho-1764808

ABSTRACT

It is increasingly common to use chatbots as an interface to use services. Making this experience more humanized requires the chatbot to understand natural language and express itself using natural language. One crucial step to achieve this is to label the data with intentions and entities. After labeling, one can use the labeled data to train a Natural Language Understanding (NLU) component. The NLU component interprets the text extracting the intentions and entities present in that text. Manually label the data is an onerous and impracticable process due to the high volume of data. Thus, an unsupervised machine learning technique, such as data clustering, is usually used to find patterns in the data and thereby label them. For this task, it is essential to have an effective vector embedding representation of texts that depicts the semantic information and helps the machine understand the context, intent, and other nuances of the entire text. In this paper, we perform an extensive evaluation of different text embedding models for clustering, labeling, and training an NLU model using the text of attendances from the Coronavirus Platform Service of Ceara, Brazil. We also show how different text embeddings result in different clustering, thus capturing different intentions of patients.

13.
Lett Appl Microbiol ; 2022 Mar 28.
Article in English | MEDLINE | ID: covidwho-1765000

ABSTRACT

Purpureocillium lilacinum is a filamentous and hyaline fungus cosmopolitan, saprophytic, largely used in the biological control of plant-parasitic nematodes and insects, also considered an emerging and opportunistic human pathogen. The standard treatment for hyalohyphomycosis caused by P. lilacinum is not yet defined, since this fungus is resistant to different antifungals, in vitro and in vivo. The aim of this study was to evaluate and compare in vitro antifungal activity against environmental and clinical P. lilacinum isolates and our results demonstrated that these isolates can be resistant to newer generation triazoles, such as voriconazole, and to caspofungin, a drug of the echinocandin class. In summary, we highlight the importance of knowing the different susceptibility profiles of P. lilacinum isolates, and besides that, the emergence of uncommon human and animal opportunistic fungi, such P. lilacinum, especially during COVID-19, highlight the need for antifungal susceptibility testing of isolates since empirical therapy with different treatment schedules failed in great number of patients.

14.
12th International Conference on Innovations in Bio-Inspired Computing and Applications, IBICA 2021 and 11th World Congress on Information and Communication Technologies, WICT 2021 ; 419 LNNS:527-536, 2022.
Article in English | Scopus | ID: covidwho-1750571

ABSTRACT

The global outbreak of Coronavirus (SARS-CoV-2) which in 2020 reached pandemic scale, has been a central topic of debate in our society. Concerns over the ease of transmission of the infection led to the imposition of measures restricting freedom such as curfews, lockdown, general confinement, and closure of trade. Technology was one of the tools used to resist to the spread of the disease using applications that, on one hand, track contacts to warn users that were close to someone infected and, on the other hand, provide immunity digital certification. Despite the relevance of these options, end users have no confidence, transparency, and responsibility that the registration and use of their health data are ethical, secure, anonymous, and available through verifiable credentials and, most importantly, is being used for its main purpose. Consequently, a solution based on a distributed ledger technology, such as blockchain, is introduced to assure the trustworthiness and integrity of user’s data. Since the proposed application embraced user privacy, we conducted a comparative study between permissioned blockchains, that includes an authorization ion layer and ensures that certain actions can only be performed by identifiable participants. We concluded that Hyperledger Fabric was an option that fulfilled all the requirements to develop a platform for the immunity passport ledger. Its modularity and versatility accommodates the needs that were initially proposed for the development of a proof of concept. The work leads us to propose that further research be conducted regarding scalability and performance evaluation. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

15.
12th International Conference on Innovations in Bio-Inspired Computing and Applications, IBICA 2021 and 11th World Congress on Information and Communication Technologies, WICT 2021 ; 419 LNNS:517-526, 2022.
Article in English | Scopus | ID: covidwho-1750570

ABSTRACT

On March 11, 2020, the novel coronavirus (COVID-19) was declared a global pandemic. With no treatment or vaccine available at the time, it was necessary to rely on non-pharmaceutical methods for case identification and contact tracing. This kind of approach has good results in detecting and preventing tuberculosis, sexually transmitted infections, and vaccine-preventable diseases. Contact tracing and keeping safe distances are crucial to containing the spread of COVID-19. Nonetheless, contact tracing is a complex intervention, it involves quarantining and investigating close contacts. Manual contact tracing methods are slow, require a large amount of effort, and more often than not rely on the memory or assumptions of individuals. To combat these downsides, contact tracing applications were developed, resulting in quicker and more reliable recognition of infected individuals. However, because of the complex nature of these applications and their lack of transparency, a large portion of the population started doubting the privacy of the data collected. Soon after, many of these applications started to dwindle in the user department, which caused a feedback loop. “If fewer people are using the application, the application itself becomes useless, and there is no longer a reason to use it.” Is clear that the main issue behind their downfall was an overwhelming lack of trust. In response, this paper will analyze how the use of blockchain technology can help the development of a more transparent application. And describe how a proof of work based on this concept was implemented. On the same note, it will also approach why was Hyperledger Sawtooth chosen, instead of more popular solutions such as Bitcoin or Ethereum. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

16.
Indian Anaesthetists Forum ; 22(2):149-156, 2021.
Article in English | Web of Science | ID: covidwho-1709700

ABSTRACT

Background: Emerging evidence suggests that liver dysfunction in the course of coronavirus disease 2019 (COVID-19) illness is a critical prognostic factor for mortality in COVID-19 patients, and the Fibrosis-4 (FIB-4) score, developed to reflect level of hepatic fibrosis, has been associated with adverse outcomes in hospitalized COVID-19 patients. This study aimed to investigate intensive care unit (ICU) admitted patients, a high-risk subpopulation, research on which is lacking. Materials and Methods: This retrospective cohort study examined FIB-4 scores and clinical endpoints including death, acute cardiac injury (ACI), acute kidney injury, and need for mechanical ventilation in critically ill COVID-19 patients, without prior hepatic disease, throughout ICU stay. Results: Of 60 patients enrolled, 35% had ICU admission FIB-4 >2.67. Among nonsurvivors, FIB-4 was significantly higher at admission (median 3.19 vs. 1.44;P < 0.001) and only a minority normalized <1.45 (36.0%). Each one-unit increment in admission FIB-4 was associated with 67.4% increased odds of death (95% confidence interval [CI], 9.8%-162.6%;P = 0.017). FIB-4 >2.67 was associated with a median survival time of 18 days from ICU admission versus 40 days with FIB-4 <2.67 (P = 0.016). Admission FIB-4 was also higher in patients developing ACI (median 4.99 vs. 1.76;P < 0.001). FIB-4 correlated with age (r = 0.449;P < 0.001), and aspartate transaminase with alanine transaminase (r = 0.674;P < 0.001) and lactate dehydrogenase (r = 0.618;P < 0.001). Conclusion: High ICU admission FIB-4 is associated with mortality in critically ill COVID-19 patients, with failure to normalize at time of death, however, the high score is likely a result of generalized cytotoxicity rather than advanced hepatic fibrosis.

17.
European Respiratory Journal ; 58:2, 2021.
Article in English | Web of Science | ID: covidwho-1708410
18.
European Respiratory Journal ; 58:2, 2021.
Article in English | Web of Science | ID: covidwho-1702815
19.
J Hosp Infect ; 123: 23-26, 2022 May.
Article in English | MEDLINE | ID: covidwho-1683310

ABSTRACT

BACKGROUND: Although the risk of SARS-CoV-2 transmission within hospitals has been well recognized, there is a paucity of data on its occurrence. Our aim was to report the incidence of hospital-acquired (HA) COVID-19 at Brazilian hospitals. METHODS: We investigated the incidence of HA COVID-19 in Brazilian hospitals using data from a national surveillance system, from August 2020 through September 2021. Definitions of HA COVID-19 were: (1) symptom onset >14 days after hospital admission plus a positive SARS-CoV-2 RNA or antigen test; (2) symptom onset on days 8-14 after admission, plus a positive SARS-CoV-2 RNA or antigen test positive, plus documented high-risk exposure. We performed descriptive analyses and reported HA COVID-19 rates using pooled mean and percentile distribution. RESULTS: A total of 48,634 cases of HA COVID-19 were reported from 1428 hospitals. Incidence ranged from 0.16/1000 patient-days at neonatal intensive care units (ICUs) to 5.8/1000 patient-days at adult ICUs. The highest incidence of HA COVID-19 was during the months March to July 2021, similar to that which was observed for community-acquired COVID-19. CONCLUSIONS: This report provides a national view of the burden of HA COVID-19. The highest incidence of HA COVID-19 similar that which was observed for community-acquired COVID-19. We believe that this reflects the difficulty of implementing preventive measures. Further studies evaluating risk factors for the hospital transmission of SARS-Cov-2 should clarify strategies to minimize the risk of HA COVID-19 and may be applicable to other respiratory diseases. Furthermore, the implementation of a national system to evaluate HA COVID-19 has the potential to shine a light on this problem and lead to interventions in each hospital.


Subject(s)
COVID-19 , Adult , Brazil/epidemiology , COVID-19/epidemiology , Hospitals , Humans , Infant, Newborn , RNA, Viral , SARS-CoV-2
20.
47th Latin American Computing Conference, CLEI 2021 ; 2021.
Article in English | Scopus | ID: covidwho-1672588

ABSTRACT

A fast way to reconstruct the three-dimensional molecular conformation of SARS-CoV-2 virus proteins is addressed in this article, involving the most worrying variant discovered in patients from Brazil, the lineage B.1.1.28/P.1. The proposed methodology is based on the sequencing of virus proteins and that, through the incorporation of mutations in silico, which are then computationally reconstructed using an enumerative feasibility algorithm validated by the Ramachandran diagram and structural alignment, in addition to the subsequent study of structural stability through classical molecular dynamics. From the resulting structure to the ACE2-RBD complex, the valid solution presented 97.06% of the residues in the most favorable region while the reference crystallographic structure presented 95.0%, a difference therefore very small and revealing the great consistency of the developed algorithm. Another important result was the low RMSD alignment between the best solution by the BP algorithm and the reference structure, where we obtained 0.483Å. Finally, the molecular dynamics indicated greater structural stability in the ACE2-RBD interaction with the P.1 strain, which could be a plausible explanation for convergent evolution that provides an increase in the interaction affinity with the ACE2 receptor. ©2021 IEEE

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