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Molecules ; 25(20)2020 Oct 13.
Article in English | MEDLINE | ID: covidwho-1305732

ABSTRACT

Nano-islands are entities (droplets or other shapes) that are formed by spontaneous dewetting (agglomeration, in the early literature) of thin and very thin metallic (especially gold) films on a substrate, done by post-deposition heating or by using other sources of energy. In addition to thermally generated nano-islands, more recently, nanoparticle films have also been dewetted, in order to form nano-islands. The localized surface plasmon resonance (LSPR) band of gold nano-islands was found to be sensitive to changes in the surrounding environment, making it a suitable platform for sensing and biosensing applications. In this review, we revisit the development of the concept of nano-island(s), the thermodynamics of dewetting of thin metal films, and the effect of the substrate on the morphology and optical properties of nano-islands. A special emphasis is made on nanoparticle films and their applications to biosensing, with ample examples from the authors' work.


Subject(s)
Gold/chemistry , Nanocomposites/chemistry , Point-of-Care Systems , Surface Plasmon Resonance/instrumentation , Animals , Biosensing Techniques/instrumentation , Growth Hormone/analysis , Humans , Lab-On-A-Chip Devices , Milk/chemistry , Nanotechnology/methods , Surface Plasmon Resonance/methods
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