Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 16 de 16
Filter
1.
Cogent Medicine ; 8, 2021.
Article in English | EMBASE | ID: covidwho-1617067

ABSTRACT

Background: Vaccination against COVID-19 in pediatric age has been a hot topic recently. This study aimed to assess parents' intention to vaccinate their children against COVID-19 and identify which factors may influence this decision. Methods: An observational study was conducted between June and July 2021 by applying an anonymous questionnaire to a sample of caregivers of children and adolescents followed in ambulatory care in a Portuguese central hospital. We included sociodemographic data, immunization history, personal background, exposure to COVID-19 and caregivers' beliefs. At the time of the study, there was still no official recommendation from health authorities regarding vaccination in pediatric age. Results: A total of 78 questionnaires were conducted. The mean age of the children was 9.2 years (±5.9), 56.4% were male, 94.8% had an updated immunization history, and 65.8% had extra vaccines. Of these children, 22.1% had comorbidities. Among the caregivers, 83.3% were mothers, the mean age was 39.4 years (±9.4), and 26.9% had attended university. The vaccine was considered safe by 61.5%, and 34.6% answered they did not know whether to consider it safe or not. Information about the vaccine was obtained through television in 84.6%, social networks in 42.3% and 34.6% in the information given by health professionals. Regarding the intention to vaccinate their children, 76.9% answered "yes", 7.7% did not answer and 15.4% answered "no". The vaccine's ineffectiveness (n=5) and inappropriate age (n=3) were the most cited reasons not to vaccinate. In 82.9%, the number of doses of the vaccine would not influence the decision. Conclusions: The study results show that caregivers have considerable resistance to the vaccination of children and adolescents against COVID-19, mainly based on the belief in the vaccine's ineffectiveness. The majority obtained information about the vaccine in the media, which reinforces the importance and the opportunity for intervention by transmitting credible and perceptible information in these media.

2.
Revista Brasileira de Parasitologia Veterinaria ; 30(4), 2021.
Article in English | Scopus | ID: covidwho-1596993

ABSTRACT

The article presents an exploratory, descriptive study on Bad News Communication skills (CMN) of medical interns. The student’s perception was on learning for the CMN was investigated with a cross-sectional design and a mixed approach. A questionnaire was applied, 176 participants were obtained, and a focus group was held with 12 students. The data were analyzed through the calculation of means and standard deviations for quantitative variables and the focus group reports were subjected to Content Analysis. It was observed that in the group that had training, compared to the one who did not, ocurred twice frequency with more skill for CMN. In the CMN’s management, it was considered harder to be “honest without taking away hope” (69%) and “to deal with the patient’s emotion” (59%). 99.4% knew the SPIKES protocol, of which 41.5% considered the expression of emotions as its most difficult stage. Communication and handling of emotions were pointed out as the main difficulties in the doctorpatient relationship, with deficits in the teaching of CMN. It was found that CMN is not limited to the technical issue, but it involves attitudes that need to be addressed with different methodologies, as well as the implementation of educational policies in the medical field, especially given the demands that emerges with the covid-19 pandemic. © 2021, Brazilain Coll Veterinary Parasitology. All rights reserved.

5.
Research and Innovation Forum, Rii Forum 2021 ; : 13-24, 2021.
Article in English | Scopus | ID: covidwho-1469594

ABSTRACT

This article presents a model that aims to identify with Machine Learning (ML) technics the main symptoms and risk factors affected in patients with Coronavirus Covid-19, registered in the database of epidemiological surveillance of state and municipal information in Brazil. The concept behind ML is the ability to learn and reason. Its application can optimize and make the treatment and care process more accurate for the cases diagnosed with the Covid-19, also known as SARS-CoV-2, adjusting the medical data recorded concerning the disease and reducing the number of symptoms and risk factors, denoting an efficient form of attribute engineering, providing those involved with the clinical observation of a minor sign. We propose an approach structured in the composition of Machine Learning algorithms, aiming to discover knowledge and concepts followed by the refinement of the results. In this article, the proposed model is presented, and a shorter trail of symptomatic observations from Covid-19 are provided. © 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.

9.
Journal of Clinical Rheumatology ; 27(SUPPL 1):S19, 2021.
Article in English | EMBASE | ID: covidwho-1368233

ABSTRACT

Objectives: To determine the main risk factors associated with COVID-19 in SLE patients. Methods: The Reuma CoV Brazil is a multicenter, observational, prospective cohort designed to monitor immune-mediated rheumatic diseases patients during SARS-CoV-2 pandemic in Brazil. SLE adult patients according to SLE SLICC criteria classification (2012), with and without (control group-CG) COVID-19 diagnosis were matched. Demographic data, managing of COVID-19, comorbidities, clinical characteristics (disease activity: Patient Report Outcomes-PROs, Physician Global Assessment and SLEDAI-2 K)were collected. Results: From May 2020 to January 2021, 604 SLE patients were included, 317 (52.4%) with COVID-19 and 287 (47.6%) in the CG. Both groups were homogeneous and comparable regarding sex and comorbidities. SLE patients with COVID-19 declared a lower level of social isolation (49.5% vs. 61.9%;p = 0.002), worked more commonly in health professions (10.4% vs. 3.5%;p = 0.002), presented more frequently joint (32.5% vs. 22.0%;p = 0.004) and hematological manifestations (18.0% vs. 11.5%;p = 0.025). SLEDAI-2 K did not differ among groups prior and after COVID-19 infection. However, considering the mean duration of COVID-19 symptoms (12.1 ± 8.8 days), infected patients had more severe disease activity's PROs after resolution of COVID-19 symptoms (2.9 ± 2.9 vs. 2.3 ± 2.6;p = 0.031). The hospitalization rate was 20.5% (n = 65), of whom 23 (7.2%) needed intensive care unit and 14 (4.4%) patients died. Hypertension [5,26 (1,9714,07);p = 0.001] and recently cyclophosphamide pulses [39,21 (4,17-368,53);p = 0.001] were associated with hospitalization and patients who received telemedicine medical care presented 72% less chance of hospitalization [0.28 (0.09-0.83);p = 0.023). Conclusion: COVID-19 was associated with a lower level of declared social isolation and more severe disease activity perception after SARS-CoV-2 infection according to PROs. Hypertension and cyclophosphamide were associated with hospitalization and telemedicine can be a useful tool for SLE patients with COVID-19. These data should be considered to perform public health policy and national guidelines to manage SLE patients during the pandemic, as well as to prioritize some special groups for the immunization program.

10.
Journal of Clinical Rheumatology ; 27(SUPPL 1):S114, 2021.
Article in English | EMBASE | ID: covidwho-1368218

ABSTRACT

Objectives: The engagement of undergraduate medical students (MS) in clinical research may lead to improvement in scientific method critical analysis, better performance as young physicians, awareness of innovation, and the development of leadership skills and teamwork perspectives (1). This study evaluated changings in daily routine and the awareness of patients' realities reported by MS participating on a research project involving rheumatic patients in Brazil during the COVID-19 pandemic. Methods: A secondary analysis of a web-based cross-sectional survey (2) including MS participating of Mário Pinotti II study (MPII) (3) was performed. Demographic characterization and the description of the MS impressions of the impact of participating of MPII are reported. Results: A total of 228 (58%) MS involved in MPII responded to the survey: 151 (66%) were women with (Mean(SD)) 22.8 (2.8) years of age, most were studying in public (N = 135 (59%)) medical schools, from 10 Brazilian states. Figures 1 and 2 summarizeMS' reports on the impact of participating of MPII on their daily routine and increased awareness of patient's realities. Conclusion: MS participating on the MPII study reported a better understanding of rheumatic patients' fears and uncertainties during the COVID-19 pandemic, including hydroxychloroquine shortage, lack of medical appointments and an unmet need related to more adequate information addressed to the rheumatic diseases. Furthermore, the close interaction among rheumatic patients, faculty, rheumatologists, and otherMShave provided a significant improvement in their feelings of usefulness during the pandemic and could contribute to their future professional activities.

11.
Annals of the Rheumatic Diseases ; 80(SUPPL 1):909-910, 2021.
Article in English | EMBASE | ID: covidwho-1358867

ABSTRACT

Background: The role of chronic use of hydroxychloroquine (HCQ) in rheumatic disease (RD) patients during the SARS-CoV-2 pandemic is still subject of discussion. Objectives: To compare the occurrence of COVID-19 and its outcomes between RD patients on HCQ use with individuals from the same household not taking the drug during community viral transmission in an observational prospective multicenter study in Brazil. Methods: Participants were enrolled and monitored through 24-week (From March 29th to Sep 30th, 2020) regularly scheduled phone calls performed by trained medical professionals. Epidemiological and demographic data, as well as RD disease activity status and current treatment data, specific information about COVID-19, hospitalization, need for intensive care, and death was recorded in both groups and stored in the Research Electronic Data Capture (REDCap) database. COVID-19 was defined according to the Brazilian Ministry of Health (BMH) criteria. The statistical analysis was performed using IBM-SPSS v.20.0 software. Group comparisons were made using the Man-Whitney, Chi-Square and Fisher Exact Test, as well as multivariate regression models adjusted to confounders. Survival curves were performed using Kaplan-Meier analysis. Results: A total of 10,427 participants mean age (SD) of 44.04 (14.98) years were enrolled, including 6004 (57.6%) rheumatic disease patients, of whom 70.8% had systemic lupus erythematosus (SLE), 6.7% rheumatoid arthritis (RA), 4% primary Sjögren's syndrome (pSS), 1.8% mixed connective tissue disease (DMTC), 1% systemic sclerosis (SSc) and others (15.9), including overlap syndromes. In total, 1,132 (10.8%) participants fulfilled criteria for COVID-19, being 6.7% RD patients and 4.1% controls (p=0.002). A recent influenza vaccination had a protective role (p<0.001). Moderate and severe COVID-19 included the need for hospitalization, intensive care, mechanical ventilation or death. Infection severity was not different between groups (p=0.391) (Table 1). After adjustments for multiple confounders, the main risk factors significantly associated with COVID-19 were higher education level (OR=1.29 95%CI 1.05-1.59), being healthcare professionals (OR=1.91;95%CI 1.45-2.53), presence of two comorbidities (OR=1.31;95%CI 1.01-1.66) and three or more comorbidities associated (OR=1.69;95%CI 1.23-2.32). Interestingly, age ≥=65 years (OR=0.20;95%CI 0.11-0.34) was negatively associated. Regarding RD, the risk factors associated with COVID-19 diagnosys were SLE (OR= 2.37;95%CI 1.92-293), SSc (OR=2.25;95%CI 1.05-4.83) and rituximab use (OR=1.92;95%CI 1.13-3.26). In addition, age ≥=65 years (OR=5.47;95%CI 1.7-19.4) and heart disease (OR=2.60;95%CI 1.06-6.38) were associated with hospitalization. Seven female RD patients died, six with SLE and one with pSS, and the presence of two or more comorbidities were associated with higher mortality rate. Conclusion: Chronic HCQ use did not prevent COVID-19 in RD compared to their household cohabitants. Health care profession, presence of comorbidities LES, SSc and rituximab were identified as main risk factors for COVID-19 and aging and heart disease as higher risk for hospitalization. Our data suggest these outcomes could be considered to manage them in clinical practice.

12.
Annals of the Rheumatic Diseases ; 80(SUPPL 1):1448, 2021.
Article in English | EMBASE | ID: covidwho-1358707

ABSTRACT

Background: Mental health was widely affected during the new coronavirus pandemic. In addition, some measures adopted by most countries in order to contain the virus spread, such as isolation and social distancing, leading to the interruption of routine activities, including partial or complete interruption of face-to-face classes may be associated with increased stress, depression and anxiety among undergraduate medical students (1). From March to September, 2020, the Brazilian Society of Rheumatology carried out the Mario Pinotti II Project (MPII), a prospective, multicenter, observational cohort study designed to monitor the COVID-19 in patients with rheumatic disease on hydroxychloroquine, using periodic telephone calls performed by undergraduate medical students (2). Objectives: To compare the mental health status of medical students who were participating from the MPII with theirs colleagues not involved in this project. Methods: A web-based survey via google forms platform was developed by a panel composed of undergraduate medical students, rheumatologists, medical school professors, and a psychology professor. It included details on demographic and life habits data and domains regarding depression, anxiety and stress, using the DASS-21 (Depression, Anxiety & Stress Scale), Brazilian version. Data collection occurred from July 20th to August 31st, 2020. Statistical analysis was performed using the SPSS version 20.0. Univariate and multivariate linear regression analysis were performed to verify associations with the DASS-21, defined as dependent variable. A p-value < 0.05 was deemed as significant. This study was approved by the Institutional Research Ethics Committee. Results: A total of 684 undergraduate medical students were included in this study, of whom 228 as MPII volunteers (VG) and 456 as control group (CG). Median age was 23 years (IQ 21-24) and the CG was older than the VG (p<0.03). Most of them were white (68.8%) and women (63%). There were no significant differences regarding comorbidities, ethnicity, smoking status, alcohol intake and physical activity. Older age, male gender, participation of MPII study, absence of a worsening in sleep pattern during the pandemic and a lower number of prior comorbidities were associated with lower DASS21 scores, suggesting a better mental health (Table 1). Conclusion: Several aspects may be involved with mental health, including increased emotional maturity, gender and sleep pattern. Although with marginal independent association, medical students with participation in the MPII study had better mental health than their student colleagues not engaged with this research. Our data pointed out that voluntary participation in a research project which foresees interaction by telephone contact with rheumatic patients, professors, rheumatologists, and colleagues is associated with better mental health.

13.
Clinical & Experimental Rheumatology ; 07:07, 2021.
Article in English | MEDLINE | ID: covidwho-1305088

ABSTRACT

OBJECTIVES: To evaluate the incidence of COVID-19 and its main outcomes in rheumatic disease (RD) patients on hydroxychloroquine (HCQ) compared to household cohabitants (HC). METHODS: This is a 24-week nationwide prospective multi-centre cohort with a control group without RD and not using HCQ. All participants were monitored through scheduled phone interviews performed by health professionals. Details regarding COVID-19 symptoms, and epidemiological, clinical, and demographic data were recorded on a specific web-based platform. COVID-19 was defined according to the Brazilian Ministry of Health criteria and classified as mild, moderate or severe. RESULTS: A total of 9,585 participants, 5,164 (53.9%) RD patients on HCQ and 4,421 (46.1%) HC were enrolled from March 29th, 2020 to September 30th, 2020, according to the eligibility criteria. COVID-19 confirmed cases were higher in RD patients than in cohabitants [728 (14.1%) vs. 427 (9.7%), p<0.001] in a 24-week follow-up. However, there was no significant difference regarding outcomes related to moderate/ severe COVID-19 (7.1% and 7.3%, respectively, p=0.896). After multiple adjustments, risk factors associated with hospitalisation were age over 65 (HR=4.5;95%CI 1.35-15.04, p=0.014) and cardiopathy (HR=2.57;95%CI 1.12-5.91, p=0.026). The final survival analysis demonstrated the probability of dying in 180 days after a COVID-19 diagnosis was significantly higher in patients over 65 years (HR=20.8;95%CI 4.5-96.1) and with 2 or more comorbidities (HR=10.8;95%CI 1.1-107.9 and HR=24.8;95%CI 2.5-249.3, p=0.006, respectively). CONCLUSIONS: Although RD patients have had a higher COVID-19 incidence than individuals from the same epidemiological background, the COVID-19 severity was related to traditional risk factors, particularly multiple comorbidities and age, and not to underlying RD and HCQ.

14.
Revista de Psiquiatria Clinica ; 48(1):12-15, 2021.
Article in English | Scopus | ID: covidwho-1282759

ABSTRACT

Background: The Brief Symptoms Inventory is a valid and reliable instrument, and one of the most often used tools to assess mental health. Despite its translation to Brazilian Portuguese, there are no normative parameters for interpretation of its scores. Objective: This study provides a normative parameter for interpretation of the performance of a large sample of adults by using a version of BSI adapted to Brazilian Portuguese. Method: We assessed 2127 adults (57% female) from all of the Brazilian regions. Normative data and Internal consistencies and performance data were calculated for the general score index and the nine factors. Results: The associations between gender and BSI scores present a significant effect size. Therefore, we provided a percentile rank parameter for the different BSI subscores, considering the whole sample and gender division. Internal consistency varies from omega equal .87 – .98 and alpha equal .86-.98, which suggests that both GSI and the nine factors have excellent reliability. Discussion: Our results support the use of the Brazilian adaptation of BSI in different regions of the country to measure mental health and its specific factors. During the pandemic of COVID-19, the establishment of normative parameters is of utmost relevance. The stability of the parameters reported here should be addressed in future studies. © 2021, UNIV SAOPAULO. All rights reserved.

15.
Infrastructures ; 6(3), 2021.
Article in English | Scopus | ID: covidwho-1186973

ABSTRACT

A holistic understanding of the correlations between supply and demand in buildings forms the basis for their performance assessment. This paper aims to reinterpret a set of Key Performance Indicators (KPIs) that influence users’ satisfaction from different perspectives. Fieldwork was carried out in an office building following a detailed review on KPIs by conducting user surveys. This study highlights the need to organize specific indicators to focus on the usability of workplaces and, where and when required, through an iterative process, understand the user perception of performance indicators in usage conditions. This methodology is applicable for organizations to understand the main existing in-service problems, and could improve the building’s performance over time. Survey results showed that hygiene was the most recognizable influence on users’ satisfaction and indoor air quality was the less well-known in the assessment results. User perception results can be compared to other office buildings results to benchmark good practices and should also be investigated for the post-COVID-19 period. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

16.
Revista da Associacao Medica Brasileira ; 66(10):1463, 2020.
Article in English | EMBASE | ID: covidwho-992867

ABSTRACT

Regarding the article “The effects of favıpıravır on hematologıcal parameters of covıd-19 patıents” with DOI number: http://dx.doi.org/10.1590/1806-9282.66.S2.65, published in Journal of the Brazilian Medical Association, 2020;66(SUPPL 2), page 65, Author’s Contribution changed: From: The authors contributed equally to the work. To: SY: Data collection, Data analysis and interpretation, Conception or design of the work, drafting the article, critical revision of the article, final approval of the version. HD: DŞ;ABG;HK;DÇ: Data collection, Conception or design of the work, data analysis and interpretation, critical revision of the article, final approval of the version. CV;AA;MK;OK: Data analysis and interpretation, final approval of the version to be published.

SELECTION OF CITATIONS
SEARCH DETAIL
...