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1.
EUROPEAN JOURNAL OF NEUROLOGY ; 29:570-570, 2022.
Article in English | Web of Science | ID: covidwho-1965421
2.
Brazilian Journal of Infectious Diseases ; 26, 2022.
Article in English | EMBASE | ID: covidwho-1693875

ABSTRACT

Objetivos: Infecções relacionada à fraturas (IRF) têm sido umas das principais complicações em paciente vítima de trauma ortopédico e na maioria das vezes estão associadas a um desfecho não favorável. No contexto da pandemia de COVID-19 ocorreu um remodelamento do perfil de pacientes e readequação de fluxo cirúrgico de pacientes com fraturas ortopédicas. O objetivo do estudo é avaliar o impacto da pandemia no desfecho clínico e cirúrgico em pacientes submetidos a correção cirúrgica de fraturas fechadas e expostas. Material e métodos: Estudo de coorte prospectivo e unicêntrico conduzido de Dezembro 2019 a Fevereiro 2021 em São Paulo - Brasil com pacientes vítimas de trauma que apresentaram fraturas ortopédicas com necessidade de abordagem cirúrgica para correção das fraturas, o objetivo de analisar o desfecho clínico e cirúrgico, avaliando a taxa de incidência e prevalência de infecção relacionada à fratura. Resultados: Foram avaliados 132 pacientes e desses, 75% eram do sexo masculino, com média de idade igual a 50,4 anos. A taxa de infecção geral foi de 15,9% sendo que 12,9% de forma tardia e 3% de forma precoce. As variáveis de risco associados à IAF, utilizando-se a análise univariada, que mostraram significância estatística foram: uso recente de antibióticos no pré-operatório (p = 0,002), tipo de fratura (exposta vs. fechada, p < 0,001), uso de fixador externo (com vs. sem, p = 0,015), osteossíntese com placa e parafuso (p = 0,006), mecanismo da lesão (acidente automobilístico vs outros, p = 0,023), infecção por COVID (p = 0,028). Todavia, após análise conjunta de forma multivariada, o uso recente e pré-operatório de antibiótico e a presença de neoplasia foram fatores de risco independente para IAF. Na análise de sobrevida para identificar os fatores de risco relacionados ao tempo até o diagnóstico de IAF e ao óbito, as variáveis que demonstraram significância estatística foram: uso de antibiótico prévio, tabagismo e as fraturas expostas. O microorganismo mais comumente isolado foi a Klebsiella pneumoniae (23,50%). Conclusão: Uso recente e pré-operatório de antibiótico, uso de fixador externo, fratura exposta, queda de altura, osteossíntese com placa e parafuso, neoplasia e infecção por Covid-19 são fatores de riscos associados ao desfecho infecção no tratamento cirúrgico de fraturas ortopédicas.

3.
Engenharia Sanitaria E Ambiental ; 26(6):1191-1204, 2021.
Article in Portuguese | Web of Science | ID: covidwho-1581624

ABSTRACT

SARS-CoV-2 is easily spread by aerosols and direct contact with contaminated people. Therefore, adverse conditions in rural areas can influence the spread of the virus. Thus, a reflection was established about the dissemination of COVID-19 due to the habits of wash hands, sanitation conditions, socioeconomic aspects, and habitability conditions in 26 rural quilombola communities in the state of Goias. For this, informations were collected in 533 locals households and it was applied the Analytic Hierarchy Process using criteria selected based on the literature. The communities presented a priority for the dissemination of COVID-19 ranging from 14.9 x 10(-3) (worst condition) to 64.3 x 10(-3) (best condition), and the Community Jose Coleto has occupied the most unfavorable position. Community Buracao showed a more satisfactory result, being less susceptible to the spread of COVID-19. Improving sanitation conditions can increase hand hygiene habits, which would reduce the spread of COVID-19 and other infectious diseases. Thus, from the results obtained, it is noticeable the importance of empowerment regarding hygiene habits, access to information, basic sanitation and health. The managers should give greater attention to implement infrastructures and improve the conditions of the criteria presented and discussed in this paper.

4.
Braz J Med Biol Res ; 55: e11631, 2021.
Article in English | MEDLINE | ID: covidwho-1575263

ABSTRACT

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused several problems in healthcare systems around the world, as to date, there is no effective and specific treatment against all forms of COVID-19. Currently, drugs with therapeutic potential are being tested, including antiviral, anti-inflammatory, anti-malarial, immunotherapy, and antibiotics. Although antibiotics have no direct effect on viral infections, they are often used against secondary bacterial infections, or even as empiric treatment to reduce viral load, infection, and replication of coronaviruses. However, there are many concerns about this therapeutic approach as it may accelerate and/or increase the long-term rates of antimicrobial resistance (AMR). We focused this overview on exploring candidate drugs for COVID-19 therapy, including antibiotics, considering the lack of specific treatment and that it is unclear whether the widespread use of antibiotics in the treatment of COVID-19 has implications for the emergence and transmission of multidrug-resistant bacteria.


Subject(s)
COVID-19 , Pandemics , Anti-Bacterial Agents/therapeutic use , Antiviral Agents/therapeutic use , Humans , SARS-CoV-2
7.
21st Congress of the International Ergonomics Association, IEA 2021 ; 221 LNNS:3-12, 2021.
Article in English | Scopus | ID: covidwho-1340346

ABSTRACT

This article presents the path traveled by a team of ergonomists to adapt the methods they used for ergonomic actions. New ways for performing ergonomic actions were necessary due to the worldwide Covid-19 Pandemic. Face-to-face observation of work activities in development was no longer possible. This study presents the challenges, limitations, and achievements obtained by ergonomists performing their work in a new way. Activity Ergonomics constitutes the theoretical reference for this work. We present the methodological association used to deal with the challenges derived from the pandemic period. We show results from the association of the Ergonomic Analysis of Work Activity (EAWA) with: the “paradigm of training in and by the analysis of work, to and by action”;the Method of Collective Work Analysis (CWA);and the Method of a Workshop of Photography. Those methods also align with the bases of the field of Workers’ Health. We conclude that the strategies adopted were able to conduct a practice in ergonomics that made it possible to achieve its main objectives. © 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.

8.
Nordic Journal of Digital Literacy ; 15(4):225-233, 2020.
Article in English | Scopus | ID: covidwho-1013586

ABSTRACT

In this introductory essay, we build on the articles in this special issue to provide a novel theoretical framework for the understanding of current and future trends in the digitalisation of teaching and learning in Nordic higher education (HE). We highlight three key elements. Context is critical and should be systematically expanded to include not only the immediate context of the virtual and blended classroom, but also the broader organisational and national contexts within which digital learning takes place. The involvement of individual actors, higher education institutions and national policy-making agencies in the development and implementation of digitalisation policy ideas and practices is also shaped by multiple mediations, which include the mediating role of technology itself, but also of other human, organisational and policy actors, ideas and practices. Finally, digitalisation of HE teaching and learning can lead to a variety of gradual or more radical digital transformations, operating at multiple scales and with multiple potential positive or negative effects. This framework helps put into focus the key question of how to go about searching for a flexible set of “Nordic characteristics” that might affect digitalisation of teaching and learning in the Nordic region, albeit in uneven and diverse ways. While it is too early to provide a systematic analysis of the impact of the rapid digitalisation of Nordic HE teaching and learning spurred by the Covid-19 pandemic, we make some preliminary observations that offer this emerging theoretical framework as a way to assess these trends both before and after the pandemic. © 2020. All rights reserved.

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