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Journal of Nepal Medical Association ; 59(237):498-503, 2021.
Article in English | Web of Science | ID: covidwho-1250012


Introduction: The alarming rate of rise in COVID-19 cases led to lockdown in Nepal in order to curb the transmission and spread of the virus among the general public. This research was conducted to know the practices regarding the COVID-19 among the general population of Nepal. The aim of the study is to find out the value of different practices regarding COVID-19 which includes use of face masks, avoiding crowded places and hand hygiene. Methods: This was a descriptive cross-sectional study conducted among 509 online respondents residing 28th November to 15th December 2020 in Nepal. Ethical approval for the study was taken from the Nepal Health Research Council (Reference number 1350). Convenient sampling method was used. Data was analyzed using Microsoft Excel and Software Statistical Package for Social Sciences version 26.0. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Out of 509 participants, 492 (96.66%) (Confidence Interval= 95.1%-98.2%) uses mask, 437 (85.85%) (Confidence Interval= 82.82%-88.87%) avoided going to crowded places and 503 (98.82%) (95% Confidence Interval= 97.88%-99.76%) practiced hand hygiene during lockdown. Among 492 (96.66%) who wore face mask during the lockdown, 482 (94.69%) were still continuing using the face mask after the restriction was eased. Conclusions: The study concludes good practises regarding COVID-19 among Nepalese population but is still not satisfying. This depicted adequate awareness among the public as a result of adequate dissemination of information and resources during the lockdown.

Journal of Pure and Applied Microbiology ; 14(3):1663-1674, 2020.
Article in English | EMBASE | ID: covidwho-891731


Severe acute respiratory syndrome coronavirus – 2 (SARS-CoV-2), an emerging novel coronavirus causing coronavirus disease 2019 (COVID-19) pandemic, has now rapidly spread to more than 215 countries and has killed nearly 0.75 million people out of more than 20 million confirmed cases as of 10th August, 2020. Apart from affecting respiratory system, the virus has shown multiple manifestations with neurological affections and damaging kidneys. SARS-CoV-2 transmission mainly occurs through close contact of COVID-19 affected person, however air-borne route is also now considered as dominant route of virus spread. The virus has been implicated to have originated from animals. Apart from bats, pangolins and others being investigates to play role in transmitting SARS-CoV-2 as intermediate hosts, the recent reports of this virus infection in other animals (cats, dogs, tigers, lions, mink) suggest one health approach implementation along with adopting appropriate mitigation strategies. Researchers are pacing to develop effective vaccines and drugs, few reached to clinical trials also, however these may take time to reach the mass population, and so till then adopting appropriate prevention and control is the best option to avoid SARS-CoV-2 infection. This article presents an overview on this pandemic virus and the disease it causes, with few recent concepts and advances.