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Ptitsevodstvo ; 9:65-69, 2022.
Article in Russian | CAB Abstracts | ID: covidwho-2148190


The successful experiment in large-scale commercial conditions is described with new vaccination program for broiler parental flock involving vaccination at 130 days of age (at the transfer of pullets to poultry houses for adult broiler breeders) with 4-valent vaccine PROVAC 4 against chicken infectious bronchitis, Newcastle and Gumboro diseases, and reoviral infection, together with additional vaccination against rhinotracheitis. Control treatment was vaccinated according to a standard scheme previously used in the farm, with separate vaccines against the aforementioned diseases;certain vaccines contained several antigens of a single disease. It was found that productive performance in the parental flocks and in broilers from these flocks was similar and consistently high with both vaccination schemes;the antibody titers at different ages of parental flocks were also similar. However, the cost of the experimental vaccination scheme was lower by 16% as compared to the standard one;on 4 batches of parental flock (120,000 hens each) it saved over 1 mio. rubles to the farm. The conclusion was made that vaccine PROVAC 4 can provide prolonged and effective protection of broiler parental flock and its progeny against viral diseases at low financial expenses.

Epidemiologiya i Vaktsinoprofilaktika ; 21(4):103-112, 2022.
Article in Russian | Scopus | ID: covidwho-2057012


Relevance. The problem of timely and effective diagnosis of COVID-19 remains one of the main problems facing healthcare. In this regard, the task of developing test systems for the etiological diagnosis of COVID-19 remains extremely relevant. Purpose To develop ELISA test system for detection of G specific immunoglobulins to SARS-COV-2 coronavirus by immunoblotting (Line Blot). Methods. Elaboration of techniques for obtaining test components and preliminary assessment of its diagnostic effectivenessin blood serums from COVID-19 patients treated at N. I. Pirogov First Gradsky Hospital, Moscow, and serums from healthy human donors. Results. The study of 104 blood serum samples from COVID-19 patients and 100 blood serum samples from healthy human donors, pre-tested by ELISA IgG to SARS-CoV-2 using «Vitrotest SARS-CoV-2 IgG» test systems (Vitrotest, Ukraine) and «ELISA-SARS-CoV-2-AB-G» (CJSC EKOlab, Russia) showed high diagnostic efficiency of the new test system. Conclusion. The new test system after state registration of the medical device can be recommended as a confirmatory test for the etiological laboratory diagnosis of COVID-19. © Mardanly SG, et al.