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Pakistan Journal of Medical and Health Sciences ; 16(8):24-26, 2022.
Article in English | EMBASE | ID: covidwho-2067738


Aim: To evaluate the potential use of ivermectin with standard therapy among mild to moderate covid-19 illness. Methods: This is a single-centered, prospective observational, randomized, parallel group (1:1 ratio), standard versus controlled ivermectin study recruited 210 confirmed COVID-19 positive patients who were admitted in COVID treatment center of Dr Ruth Kum Pafu Civil hospital Karachi, Pakistan from 1st November 2020 to 30th May 2021. Data were analyzed using SPSS version Results: Total of 210 patients were enrolled in the study and aged matched patients were divided in two groups 105 patients received ivermectin 6 mg twice a day for five days along with standard therapy while remaining 105 patients received standard therapy as per local and international guidelines. Male were 140(66.7%) and female 70(33.3%);age ranges between 26 to 77 years and majority 140( 66.7%) were more than 50 years of age. Fever, dry cough and dyspnea were the major symptoms seen;112(53.3%) patients had DM as a comorbid illness . Total of 21(20%) of 105 patients of ivermectin group had negative PCR for COVID 19 on day seven while the other group had positive covid test in all of 105 patients . On day 10 total of 49 more patients from ivermectin group found COVID negative along with 21 previously negative had second PCR was found negative in this way total of 70( 66.7%) of ivermectin group had negative PCR for COVID 19 while 21(20%) patients from non ivermectin got negative PCR for COVID 19 on day 10 . Conclusion: Use of ivermectin with standard therapy clear the virus earlier than standard therapy in mild to moderate COVID-19 infected patients admitted in COVID treatment center of Dr Ruth Kum Pafu Civil Hospital Karachi.

Pakistan Journal of Medical and Health Sciences ; 15(4 April):706-709, 2021.
Article in English | EMBASE | ID: covidwho-1232873


Aim: To assess the knowledge, attitude and practice of the general population after six months of outbreak. Methods: A cross-sectional survey was conducted on the general population in the month of July 2020. In which the general population was randomly selected and assessed for knowledge, attitude and practice about COVID19. The questionnaire was designed to avoid any privacy information and all questions were mandatory to answer. Results: Total of 1200 participants enrolled male 552(46%) and female 648(54%). Age ranges between 20 to 60 years and education status of responders were divided into middle, higher secondary and graduate respectively;they were 192(16%), 420(35%) and 588(49%). Knowledge assessed through symptom & virus transmission questions fever, fatigue and dry cough responded by 768(64%) while rest question knowledge were very poor. Practice questions responses to the virus were very much disturbing and most believe hype created by government and media, admission causes loss of loved ones and doctors are responsible for giving death injections to admitted peoples. Only 768(64%) of respondents regularly sanitize hands and wash with soap. Conclusion: Response to the question in KAP study was very poor despite six month had been passed in outbreak, yet it is necessary to improve the knowledge by arranging online seminars, media talk and strong awareness campaign required to improve knowledge & motivate their attitude toward virus which will resulting good practice to avoid further transmission of infection.