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1.
2022 International Conference on Computation, Big-Data and Engineering, ICCBE 2022 ; : 140-145, 2022.
Article in English | Scopus | ID: covidwho-2078210

ABSTRACT

Schedule control is a key part of project management. The delayed schedule leads to a conflict of interest for the stakeholders involved in the project management process. The degrees of conflict resolution usually reflect the level of project management. We propose a graph model for conflict resolution (GMCR) for the improvement of interest conflicts among stakeholders including developers, contractors, and governments in engineering projects affected by the COVID-19 pandemic-projects suspended due to the epidemic gradually resumed work and production with the recovery of the epidemic. The developer asks the contractor to speed up the process to complete the project within the agreed time limit. However, the contractor has a heavy financial burden during the epidemic. Speeding up the process means more expenses, resulting in bargaining and further conflict. The model uses hesitant fuzzy preferences to express the preference information of DMs composed of multiple individuals, develops an analytic hierarchy process (AHP) that considers the potential contribution of stakeholders to prioritize relative preferences, and finally uses hesitant fuzzy preference relations to extended stability analysis and obtains equilibrium decisions, which verifies the effectiveness of the method. © 2022 IEEE.

2.
Frontiers of L2 Chinese Language Education: A Global Perspective ; : 51-67, 2021.
Article in English | Scopus | ID: covidwho-2055825

ABSTRACT

This paper addresses the critical issue of student engagement in the online delivery of university Chinese courses during COVID-19. It first outlines principles of student-centered course design in the context of the full-scale online conversion. It then focuses on two main approaches to student engagement. One approach is to leverage active communication with students both before and during the semester for the purpose of learning-community building. The other approach is to design and apply pedagogical innovations to address challenges inherent in online Chinese teaching and to enhance student learning experiences and outcomes. The presentation is reinforced with critical reflections of those feasible hands-on strategies, students’ feedback and demonstrated learning outcomes. It is hoped that the sharing of the lived teaching experience and critical reflections will contribute to the understanding and improvement of online Chinese teaching and will eventually inspire and empower our students in their learning odyssey. © 2022 selection and editorial matter, Yanyin Zhang and Xiaoping Gao;individual chapters, the contributors.

3.
Chinese Journal of Lasers-Zhongguo Jiguang ; 49(15), 2022.
Article in English | Web of Science | ID: covidwho-2006271

ABSTRACT

Objective The ongoing coronavirus pandemic has propelled the need for new approaches to disinfection, especially for airborne viruses. The 254 nm emission of low-pressure vacuum lamps is known for its antimicrobial effect;however, its radiation is harmful to human health, causing skin cancer and cataracts. Some studies have shown that short-wavelength ultraviolet (UV) light in the spectral region of 200-230 nm (far-UVC) can inactivate pathogens without harming human cells. Thus, it has great prospects for many applications. Sufficient studies have proved the antibacterial performance of far-UVC band range in an excimer lamp emitting a peak wavelength of 222 nm light. Furthermore, laser light sources can realize long-distance transmission and complement the deficiency of excimer lamps in remote sterilization and disinfection. This study investigates the antibacterial effect of a self-developed far-UVC laser with a peak wavelength of 228 nm and hopes to provide a new technical approach for the inactivation of the novel coronavirus and other microbial pathogens. Methods Bacterial sample preparation: Escherichia coli (E. coli) widely exists naturally and is a pathogen of major focus in human public health defense. It is also one of the most drug-resistant species in the enterobacterium group. Therefore, it is often used in ultraviolet disinfection and environmental health research. Bacillus cereus (B. cereus), which is closely related to humans, causes food poisoning and cannot be eliminated by pasteurization or normal hygiene procedures due to the heat and acid resistance of its spores. Therefore, the strains used in this experiment are E. coli and B. cereus. E. coli and B. cereus are provided by the Ministry of Education Key Laboratory for Ecology of Tropical Islands, Hainan Normal University, and subsp. Kustaki HD-1, provided by the Environmental Microbial Ecology Laboratory of Hainan Normal University. Both strains are cultured in a nutrient agar medium and placed in an incubator at 35 degrees C for 1 day. Nutrient agar medium is provided by Guangdong Huankai Microbial Technology Co., LTD, China. UV irradiation source: the irradiation source is a self-developed all-solid-state 228 nm far-UVC laser, which provides UV irradiance of up to 35 mW/cm(2), and its spectral linewidth is less than 0.1 nm. The laser is realized by LD-pumped Nd3+ laser crystal, Q-switched technology, and nonlinear optical frequency conversion technology. All-solid-state lasers have the advantages of small size, high efficiency, good beam quality, high reliability, long life, and portability. 228 nm far-UVC laser sterilization: we input a certain concentration of 1 mL bacterial suspension sample into a high permeability UVC cuvette. The 228 nm laser irradiance of 0.1 mW/cm(2) is obtained by adjusting the laser output power and the placement of the colorimeter. E. coli suspension samples are irradiated for 5, 10, 15, and 20 s [Fig. 1 (b), and B. cereus suspension samples are irradiated for 15, 30, 45, and 60 s [Fig. 1(c)] at 228 nm far-UV light of 0.1 mW/cm(2). The experiment is repeated three times for each sample at the same irradiation dose. Results and Discussions Figs. 1 (b) and (c) show the distribution of bacteria before and after 228 nm laser irradiation. The concentration of bacterial suspension samples in the control and irradiated groups is determined using the nutrient agar plate counting method. The detection results are shown in Table 1. When the E. coli suspension is irradiated by 228 nm laser for 10, 15, and 20 s (1, 1.5, and 2 mJ/cm(2)), the inactivation rates are 90. 7 %, 96.9 %, and 100 yo, respectively. When the B. cereus suspension is irradiated by 228 nm laser for 30, 45, and 60 s (3, 4. 5, and 6 mJ/cm(2)), the inactivation rates are 88. 4%, 98.6 %, and 100 %, respectively. Conclusions This experimental study shows that the use of several mJ/cm(2) doses of far-UVC 228 nm pulsed laser irradiation can effectively inactivate E. coli and B. cereus, whereas the use of excimer lamps requires dozens of mJ/cm(2) doses. Compared with the excimer light source, the far-UVC pulsed laser light source shows a stronger sterilization effect. The next step is to conduct experimental research on the inactivation of the influenza virus using a far-UVC 228 nm pulsed laser.

4.
International Journal of Business Communication ; : 24, 2022.
Article in English | Web of Science | ID: covidwho-1978745

ABSTRACT

The COVID-19 pandemic has posed severe challenges that require collaborative efforts from multi-sector organizations. Guided by an institutional theory framework that considers how both organizational fields and national level contexts affect organizations' social partnership communication, the current study examines the COVID-19-related social partnership communication network on social media. The cross-national study using semantic network analysis and exponential random graph models (ERGMs) first maps the meaning of COVID-19 social partnership network, and then investigates the role of organizational fields and a country's political system, economic system, educational system, and cultural system on the formation of interorganizational communication ties surrounding the relief efforts of COVID-19. Results reveal the importance of the political system-such as the presence of populist government, economic disparity, and uncertainty avoidance cultural orientation in shaping the social media-based social partnership communication network. In addition, NGOs from multiple issue areas are actively engaged in the network, whereas corporations from manufacturing and financial industries are active players.

5.
International Perspectives in Psychology: Research, Practice, Consultation ; 11(3):141-152, 2022.
Article in English | Scopus | ID: covidwho-1972531

ABSTRACT

The COVID-19 pandemic has affected all societies worldwide. The heightened levels of stress that accompanied the crisis were also expected to affect parenting in many families. Since it is known that high levels of stress in the parenting domain can lead to a condition that has severe consequences for health and well-being, we examined whether the prevalence of parental burnout in 26 countries (9,923 parents;75% mothers;mean age 40) increased during COVID-19 compared to few years before the pandemic. In most (but not all) countries, analyses showed a significant increase in the prevalence of parental burnout during the pandemic. The results further revealed that next to governmental measures (e.g., number of days locked down, homeschooling) and factors at the individual and family level (e.g., gender, number of children), parents in less (vs. more) indulgent countries suffered more from parental burnout. The findings suggest that stricter norms regarding their parenting roles and duties in general and during the pandemic in particular might have increased their levels of parental burnout. © 2022 Hogrefe Publishing.

6.
Xitong Gongcheng Lilun yu Shijian/System Engineering Theory and Practice ; 42(6):1463-1480, 2022.
Article in Chinese | Scopus | ID: covidwho-1924682

ABSTRACT

In this paper, we explore the transmission of risks induced by macroeconomic shocks from real economy to financial sector. We first construct a two-period general equilibrium model that includes households, firms and banks, to reveal the mechanism of macroeconomic shocks affecting bank risks. Based on a quarterly dataset of 14 major listed banks and their lending-related firm clients from 2017 to 2020, we empirically test the firm leverage channel through which macroeconomic shocks (Corona Virus Disease 2019 as an instance) affect bank risks. The results show that: 1) The increase in the firm leverage will significantly push up the risk of banks that provide credit services for these firms;2) macroeconomic shocks could further intensify the positive correlation between firm leverage and bank risk;3) the previous findings are more prominent among joint-stock banks, state-owned and large enterprises. In addition, the impact of firm leverage on bank risk under macroeconomic shocks is more pronounced for the 50% and lower quantiles of the distribution. © 2022, Editorial Board of Journal of Systems Engineering Society of China. All right reserved.

7.
Fertility and Sterility ; 116(3 SUPPL):e363, 2021.
Article in English | EMBASE | ID: covidwho-1880482

ABSTRACT

OBJECTIVE: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of people. With the development and administration of the SARS-CoV-2 vaccines, there is growing evidence to suggest that there has been reduced transmission of the virus. However, the novelty of the vaccine has raised many questions for infertility patients due to the lack of research. This study examines the perceived anxiety level of patients at a fertility clinic in Manhattan who are undergoing infertility treatments, such as Timed Intercourse (TIC), Intrauterine Insemination (IUI), and In-Vitro Fertilization (IVF). Understanding the mental state of patients with infertility problems during the COVID-19 pandemic is vital for fertility clinics in their future patient assessments. MATERIALS AND METHODS: Surveys were administered to approximately 100 patients at a fertility clinic in Manhattan during early April 2021 - a few months after the first Covid vaccine was administered in the USA. The questionnaire asked patients to specify their treatment plan (TIC, IUI, IVF, oocyte cryopreservation, or no infertility problem). The survey included a 20-item Spielberger State-Trait Anxiety Inventory (STAI) assessing their current state of anxiety. For the STAI score cutoff, <40 = not anxious;40+ = high anxiety. Continuous variables were measured as mean and standard deviation and compared with a two-sample t-test or ANOVA. Categorical variables were compared with a Fisher test. A p-value <0.05 was considered statistically significant. Statistics were done with R version 4.0.5. RESULTS: There is no statistical significance in which group was more likely to have received at least one dose of the COVID-19 vaccines. However, the ''undecided'' group had the lowest percentage of individuals receiving the vaccine. There is also no statistical significance in the anxiety levels of the different groups of patients. The group with the greatest percentage of anxiety according to the STAI score is the ''undecided'' group. Fear of the COVID-19 virus being greater than the fear of the COVID-19 vaccine is a commonality between all the groups. CONCLUSIONS: The survey found that the greatest cause of apprehension in patients was the virus's unknown effects on their physical health. Majority of the hesitancy in receiving the vaccine was due to the potential side effects posed by the injection on pregnant women and their fetus. Interestingly, patients not in treatment had a trend towards higher fear and anxiety compared to patients undergoing infertility treatment. When broken down even further, patients who are undecided in their treatment are more anxious about both the COVID-19 virus and the vaccine. This indicates that the patient's treatment plan influences their view of the pandemic. IMPACT STATEMENT: Women with infertility issues experience tremendous amount of emotional turmoil, which can further interfere with their fertility. Recognizing the root of this population's anxiety during the COVID-19 pandemic can assist reproductive endocrinologists in forming treatment plans that integrate management of patient's psychological wellbeing.

8.
Journal of Environmental Protection and Ecology ; 23(2):454-461, 2022.
Article in English | Web of Science | ID: covidwho-1865979

ABSTRACT

In the context of the global outbreak of COVID-19, health issues have attracted worldwide attention. Building a healthy ecological environment is particularly important for human beings, and among the ecological environmental factors, air quality is particularly prominent. The study takes the air quality of newly-built immigrant relocation communities in Western China as the research object, and adopts a number of technical methods, such as professional laboratory test report, instrument test, calculation test and so on. Obtain the data of regional ambient air quality and building indoor air quality, and comprehensively judge the regional environment and building ventilation efficiency of the experimental point. So as to comprehensively grade the air quality of the experimental point. A number of technologies and methods are studied and integrated to form a comprehensive three-dimensional air quality detection technology integration. From the perspective of air quality inspection, provide technical support for the healthy and sustainable development of relocated new rural communities. It is of great practical significance to supervise and urge the construction of a healthy and sustainable new township village.

9.
British Journal of Management ; : 20, 2021.
Article in English | Web of Science | ID: covidwho-1583727

ABSTRACT

Previous research mostly examines supervisor-directed deviance as a subordinate's reaction to the supervisor's abusive behaviour while ignoring the perspective of supervisors as potential victims of deviant behaviour. Additionally, COVID-19 has deeply affected organizational climate and workplace behaviour. Therefore, drawing on the affective events theory, we examined the COVID-19 pandemic as a context shaping the effects of supervisor-directed deviance on retaliation against subordinates in the United States. We conducted two quasi-experiments with pre- and post-COVID-19 (Study 1, n = 97) and Wave 1-Wave 3 pandemic study designs (Study 2, n = 94), respectively, and found that supervisor-directed deviance triggered felt leader identity threat, consequently leading to retaliation against subordinates;this indirect effect strengthened as the pandemic progressed. We replicated these findings using a field study during the third wave of the pandemic (Study 3, n = 190), which established external validity by expanding the types of deviant and retaliatory behaviours examined. The results further showed that low COVID-19-induced empathic concern strengthened the effect of felt leader identity threat on retaliatory responses. Overall, our paper contributes to the literatures on retaliation and supervisor-directed deviance and opens avenues for research on the pandemic's impact on organizational behaviour.

10.
Zhonghua Liu Xing Bing Xue Za Zhi ; 42(5): 923-927, 2021 May 10.
Article in Chinese | MEDLINE | ID: covidwho-1534266

ABSTRACT

Three healthcare revolutions and four medical paradigm shifts have had a profound impact on the development of healthcare system, which has greatly improved human health, however, the COVID-19 pandemic has exposed hidden dangers and problems in the construction of the healthcare system. In this paper, we made a brief introduction of population medicine and value-based healthcare for the purpose of suggesting new ideas and directions for the future development of healthcare system.


Subject(s)
COVID-19 , Pandemics , Delivery of Health Care , Health Facilities , Humans , SARS-CoV-2
12.
Crystal Growth and Design ; 2021.
Article in English | Scopus | ID: covidwho-1284672

ABSTRACT

Recently, favipiravir, as a broad-spectrum antiviral drug, has gain more attention because it might be a candidate to remedy the coronavirus disease 2019 (COVID-19). To improve its poor permeability and tabletability, four multicomponent crystals of favipiravir (FPV) were prepared by a slow evaporation or liquid-assisted grinding method, including three cocrystals (FPV-theophylline, 1:1;FPV-saccharin, 1:1;FPV-5-fluorouracil, 1:1) and one salt (FPV-piperazine, 2:1). All of the crystal structures were solved by single-crystal X-ray diffraction. Interestingly, FPV-theophylline has a crystal structure similar to that of FPV, leading to similar properties, such as solubility, permeability, and tabletability. Except for FPV-theophylline, all of the other multicomponent crystals exhibit an enhanced permeability and tabletability. Our studies provide a new insight in overcoming the shortcomings of the important antiviral drug FPV. ©

13.
Acta Medica Mediterranea ; 37(3):1323-1329, 2021.
Article in English | EMBASE | ID: covidwho-1278833

ABSTRACT

Introduction: To date, seven human coronaviruses (HCoVs) have been discovered. SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a newly emerged HCoV, which can induce fatal pneumonia infection. Coronavirus is a single-stranded RNA virus that is susceptible to mutation, making it difficult to develop vaccines. Broad-spectrum vaccines based on conserved neutralizing epitopes can not only prevent epidemic strains, but also has broad-spectrum antiviral property. In this study, bioinformatics was used to predict broad-spectrum neutralizing epitopes of HCoVs. Methods: The spike (S) protein amino acid sequence of SARS-CoV-2 Wuhan-Hu-1 strain was used as a template for epitope prediction. The linear B cell neutralization epitopes were primarily predicted by four online prediction servers, including ABCpred2006, BepiPred2.0, COBEpro and SVMTriP. The peptide fragments were selected according to their common prediction results, and were further screened using the server VaxiJen2.0. The conservation of high-score candidate epitopes was analyzed by Clustal X2 software, and the spatial position of candidate epitopes in S protein were analyzed by the PyMOL software. Results: According to the analysis above, four potential broad-spectrum linear B cell neutralizing epitopes were screened, which include the epitopes P6 (aa496-501) and P14 (aa1163-1168) conserved between SARS-CoV-2 and SARS-CoV;P15 (aa1196-1201) conserved among SARS-CoV-2, SARS-CoV and MERS-CoV;P12 (aa811-816) conserved among SARS-CoV-2, SARS-CoV and HCoVOC43. Conclusions: Four potential broad-spectrum linear B cell neutralizing epitopes in the S protein of SARS-CoV-2 were predicted, which lay a foundation for the development of HCoVs broad-spectrum vaccines.

14.
Vaccines (Basel) ; 9(4):01, 2021.
Article in English | MEDLINE | ID: covidwho-1208547

ABSTRACT

BNT162b2 is a highly efficacious mRNA vaccine approved to prevent COVID-19. This brief report describes the immunogenicity and anti-viral protective effect of BNT162b2 in hACE2 transgenic mice. Prime-boost immunization with BNT162b2 elicited high titers in neutralizing antibodies against SARS-CoV-2, which correlated with viral clearance and alleviated lung lesions in these mice after viral challenge.

15.
Yaoxue Xuebao ; 55(3):374-383, 2020.
Article in Chinese | EMBASE | ID: covidwho-918557

ABSTRACT

Traditional Chinese medicine (TCM) network pharmacology and molecular docking technology were applied to explore the mechanism of anti-coronavirus pneumonia (coronavirus disease 2019, COVID-19) of Qingfei Paidu decoction. The Chinese Pharmacopoeia (2015 edition) and Traditional Chinese Medicine Systems Pharmacology (TCMSP), OMIM (Online Mendelian Inheritance in Man), GeneCard, STRING, and others online databases are used for building a series of network, and selecting the core target and analyzing the signal pathway. Finally, we make molecular docking predictions for the important compounds. The results showed that the Qingfei Paidu decoction compound-pneumonia target network contained 292 compounds and 214 corresponding targets, and the core targets involved AKT1 (AKT serine/threonine kinase 1), IL6 (interleukin 6), MAPK8 (mitogen-activated protein kinase 8), MAPK1 (mitogen-activated protein kinase 1), and JUN (jun proto-oncogene). GO (Gene Ontology) function enrichment analysis yielded 858 GO entries, and KEGG (Kyoto Encyclopedia of Genes and Genomes) enrichment screening yielded 122 related pathways, including hypoxia inducible factor-1 (HIF-1) and Toll-like receptor (TLRs) signaling pamways related to pneumonia, as well as T-cell receptor (TCR) signaling pathway related to lung injury protection. The molecular docking results showed that some core compounds of the Chinese herbal medicine of Qingfei Paidu decoction have a certain degree of affinity for 2019-novel coronavirus (2019-nCoV) main protease (3C-like protease, 3CLpro) and angiotensin-converting enzyme 2 (ACE2). In this paper, we preliminarily explored the potential therapeutic mechanism for Qingfei Paidu decoction to against COVID-19 and predicted the active ingredients. We hope mat me results will help to the further study on me active ingredients and mechanism of Qingfei Paidu decoction to COVID-19.

16.
Research of Environmental Sciences ; 33(7):1618-1623, 2020.
Article in Chinese | Scopus | ID: covidwho-833184

ABSTRACT

On March 11th, 2020, WHO declared a global pandemic of COVID-19. The occurrence of viral infectious diseases in the population should have three interrelated conditions, namely the infection source, the transmission way and the susceptible population, and the transmission way is a key link. From the perspective of environmental transmission, the survival time and influencing factors of viruses, such as SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) on inanimate surfaces were reviewed. The results showed that some infectious virus, including coronaviruses, could survive for hours to days on a variety of inanimate surfaces, which might result in virus spread in the environment and potential health risks. Object materials, temperature, humidity and virus load were the main factors affecting the survival of viruses on inanimate surfaces. Based on the above analysis, specific prevention and control measures were proposed for the collection, transportation and treatment of medical waste and household waste, in order to provide reference for taking effective measures to control 2019-nCoV and other viruses in the future. © 2020, Editorial Board, Research of Environmental Sciences. All right reserved.

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