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1.
Photodiagnosis Photodyn Ther ; 37: 102643, 2022 Mar.
Article in English | MEDLINE | ID: covidwho-1531705

ABSTRACT

BACKGROUND AND AIM: Among the most common symptoms of COVID-19 is taste dysfunction, which has a ranging clinical presentation. As well as its pathophysiology remains to be unclear, there is not enough information about the efficacy and safety of the available treatments. This study aims to report a series of cases using PBMT for the management of COVID-19-related taste impairment. CASE SERIES: 8 female and 2 male patients sought medical help for taste impairment (either partially or completely) after COVID-19 infection. Photobiomodulation therapy (PBMT) on the tongue mucosa was then proposed but with 3 different protocols. Taste perception at baseline and before every laser session was evaluated using a visual analog scale. Irrespective of the PBMT protocol, taste recovery was noted in all cases but with varying degrees of improvement. CONCLUSION: given the high prevalence rates of taste dysfunction in COVID-19 patients and the lack of information about the available treatments, PBMT seems to be a promising therapeutic modality but not dependent on the total number of laser sessions and the interval between them. The choice of the most suitable laser protocol as well as the knowledge of the exact photonic mechanisms, however, need to be better studied.


Subject(s)
COVID-19 , Low-Level Light Therapy , Photochemotherapy , Female , Humans , Low-Level Light Therapy/methods , Male , Photochemotherapy/methods , SARS-CoV-2 , Taste Disorders/etiology
2.
Photodiagnosis Photodyn Ther ; 36: 102574, 2021 Dec.
Article in English | MEDLINE | ID: covidwho-1458817

ABSTRACT

Olfactory dysfunction is commonly seen in COVID-19 patients; however, little is known about the pathophysiology and management. The present study aimed to report a series of cases in which three protocols of intranasal photobiomodulation therapy (PBMT) were used for COVID-19-related olfactory dysfunction. Irrespective of the PBMT protocol, olfaction recovery was noted in all cases but with varying degrees of improvement. Although intranasal PBMT seems to be a promising therapeutic modality, more research is needed to better define effectiveness.


Subject(s)
COVID-19 , Low-Level Light Therapy , Olfaction Disorders , Photochemotherapy , Humans , Olfaction Disorders/drug therapy , Olfaction Disorders/therapy , Photochemotherapy/methods , Photosensitizing Agents/therapeutic use , SARS-CoV-2 , Smell
3.
Photodiagnosis Photodyn Ther ; 33: 102196, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-1051903

ABSTRACT

Many oral signs and symptoms related to the novel coronavirus disease (COVID-19) have been reported; however, both prevalence and etiology are still undetermined. Since the clinical features of the oral lesions seen in COVID-19 are highly heterogeneous and the treatments differ considerably in the literature, the present study aimed to report a clinical case in which a combination of antimicrobial photodynamic therapy (aPDT) and photobiomodulation therapy (PBMT) was used for extensive lip lesions in a patient suffering from COVID-19. Within 4 days and without any systemic drug administration, after two sessions of aPDT and one session of PBMT, the lip lesions were completely healed, and the patient recovered her orofacial functions satisfactorily. According to the current case report and taking into consideration the evident lack of information about many aspects of COVID-19 infection, this combination of phototherapy modalities seems to be a promising tool for managing COVID-19-related lip lesions; however, more studies are necessary.


Subject(s)
COVID-19/pathology , Lip/drug effects , Lip/pathology , Low-Level Light Therapy/methods , Photochemotherapy/methods , Female , Humans , Methylene Blue/therapeutic use , Middle Aged , Photosensitizing Agents/therapeutic use , SARS-CoV-2
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