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1.
Cogent Medicine ; 8, 2021.
Article in English | EMBASE | ID: covidwho-1617065

ABSTRACT

Background: The COVID-19 pandemic has changed the paradigm when it comes to infection control. However, there are still many doubts about pregnancy and the perinatal period in this context, even though many studies suggest the benignity of infection in this phase. The present study took place in a Level II Hospital with differentiated perinatal care and describes the newborns whose mothers were infected with COVID-19 during pregnancy. We aim to understand the mother-newborn pattern of transmission and clinical, analytical and serologic follow-up. Methods: Prospective observational study from 1/4/2020 to 31/5/2021, using the clinical files of every SARS-COV-2 PCR-positive mother and their newborns. Among others, we evaluated the state of infection of the newborn at 12 and 48h and after 14 days with SARS-Cov-2 PCR tests. In the first three months, serologic and clinical evaluation were performed. Results: Of the 1684 live births, 60 (3,6%) mothers were infected with SARS-COV-2 during pregnancy, 43% of which were diagnosed in the screening performed during/before labour. The median value of gestational age was 39 weeks, and the average weight was 3171g. 81,7% of the newborns remained with their mother in the hospital ward, and 85% were breastfed. 7 newborns (11,7%) needed NICU, one of which was born at 32 weeks because the mother needed ICU support due to COVID-19. Of the 26 newborns whose mothers were positive in labour, 15 were tested for SARS-Cov-2 PCR in the first 12 h, and 21 within 48h: all of them were negative.16 were tested after 14 days. Only one of them (6,2%) tested positive but remained asymptomatic. Serologic anti-spike and anti-nucleocapsid analyses were performed in 32 babies: 10 of them (31.3%) showed positive antibodies. In these cases, 80% of the mothers were positive in the 3rd trimester and 20% in the 2nd trimester. The clinical follow-up showed a positive outcome in all of them. Conclusions: This study supports others that show the benignity of perinatal SARS-COV-2 infection. There were no more significant rates of prematurity or NICU need. None of the newborns tested positive in SARS-Cov-2 PCR tests in the first 48h, supporting the rarity of the vertical infection, and only one has been affected by horizontal transmission.

3.
16th Iberian Conference on Information Systems and Technologies, CISTI 2021 ; 2021.
Article in English | Scopus | ID: covidwho-1449455

ABSTRACT

In the context of the COVID-19 pandemic, mobile applications have been widely used and promoted to help prevent the spread of the pandemic. Many countries have proposed these applications with the aim of improving contact tracing and thus helping "flatten the curve"of infection case numbers. However, even though there were many campaigns to promote the use of these apps, their adoption was relatively low, which significantly affected their success. The success of COVID-19 contact tracing apps, in terms of its massive use and effectiveness, seems to have been deeply affected by issues associated with privacy and anonymity and the perception that its potential users have about the cost/benefit. In this paper, we analyze some applications for monitoring and contact tracing of infectious diseases to identify the most common approaches and features. We then proceed to discuss the challenges and risks that may influence the success of this type of applications, and we present some recommendations that can contribute to improve their acceptance. Considering the proposed recommendations, we describe the main features and the development of an app that includes additional functionalities alongside the contact tracing feature, in order to increase user perceived value from the use of the application. © 2021 AISTI.

5.
Journal of Clinical Rheumatology ; 27(SUPPL 1):S19, 2021.
Article in English | EMBASE | ID: covidwho-1368233

ABSTRACT

Objectives: To determine the main risk factors associated with COVID-19 in SLE patients. Methods: The Reuma CoV Brazil is a multicenter, observational, prospective cohort designed to monitor immune-mediated rheumatic diseases patients during SARS-CoV-2 pandemic in Brazil. SLE adult patients according to SLE SLICC criteria classification (2012), with and without (control group-CG) COVID-19 diagnosis were matched. Demographic data, managing of COVID-19, comorbidities, clinical characteristics (disease activity: Patient Report Outcomes-PROs, Physician Global Assessment and SLEDAI-2 K)were collected. Results: From May 2020 to January 2021, 604 SLE patients were included, 317 (52.4%) with COVID-19 and 287 (47.6%) in the CG. Both groups were homogeneous and comparable regarding sex and comorbidities. SLE patients with COVID-19 declared a lower level of social isolation (49.5% vs. 61.9%;p = 0.002), worked more commonly in health professions (10.4% vs. 3.5%;p = 0.002), presented more frequently joint (32.5% vs. 22.0%;p = 0.004) and hematological manifestations (18.0% vs. 11.5%;p = 0.025). SLEDAI-2 K did not differ among groups prior and after COVID-19 infection. However, considering the mean duration of COVID-19 symptoms (12.1 ± 8.8 days), infected patients had more severe disease activity's PROs after resolution of COVID-19 symptoms (2.9 ± 2.9 vs. 2.3 ± 2.6;p = 0.031). The hospitalization rate was 20.5% (n = 65), of whom 23 (7.2%) needed intensive care unit and 14 (4.4%) patients died. Hypertension [5,26 (1,9714,07);p = 0.001] and recently cyclophosphamide pulses [39,21 (4,17-368,53);p = 0.001] were associated with hospitalization and patients who received telemedicine medical care presented 72% less chance of hospitalization [0.28 (0.09-0.83);p = 0.023). Conclusion: COVID-19 was associated with a lower level of declared social isolation and more severe disease activity perception after SARS-CoV-2 infection according to PROs. Hypertension and cyclophosphamide were associated with hospitalization and telemedicine can be a useful tool for SLE patients with COVID-19. These data should be considered to perform public health policy and national guidelines to manage SLE patients during the pandemic, as well as to prioritize some special groups for the immunization program.

6.
Online Journal of Communication and Media Technologies ; 11(3), 2021.
Article in English | Scopus | ID: covidwho-1350647

ABSTRACT

Local media are decisive for communities in the context of a global culture. In Portugal, communicating for a more geographically restricted area deals with permanent hazards, especially in the journalistic scope, from both structural and organizational points of view. Arguably weakened and lacking from institutional support, Portuguese local media, ranging from printed media, radio, and television to online broadcasts, still thrive on uncertainty. Also, from an academic point view, little is known about the audiences’ perceptions towards these local media. In doing so, this article presents the data collected from an online survey of 139 consumers of local media, thus concluding: traditional media (printed and FM) are still the most consumed formats, compared to the online scope;the COVID-19 pandemic was not decisive to increase local media consumption habits;seeking for information is the fundamental reason to follow local media;participants understand that websites and Facebook, mainly, are the most dynamic digital spaces that local media foster, thus giving them a very good evaluation;half of the sample have already interacted with broadcasters, especially to suggest ideas for journalistic approaches;in a global perspective, participants are pleased with the news coverage of local media towards local matters. Future research should implement complementary scientific approaches, based on in-depth perspectives to fully understand motivations to engage with local media and other social representations towards these mass media. © 2021, Bastas Publishing. All rights reserved.

8.
Revista de Filosofia: Aurora ; 32(57):940-964, 2020.
Article in Portuguese | Scopus | ID: covidwho-1016396

ABSTRACT

Na manhã de 10 de janeiro de 2020, no anfiteatro da Université de Toulouse (Jean Jaurès), com olhos e ouvidos bem abertos, estudantes da França, do Brasil e de outras nacionalidades assistiam à conferência do filósofo Vladimir Safatle, professor da Universidade de São Paulo. No púlpito, ele comentava o significado da estruturação psíquica paranoica, tal como descrita por Freud, e como ela ganharia status de normalidade em determinados contextos sociais e políticos que hoje não nos são nada estranhos. Nem sequer desconfiávamos, no âmbito daquele conjunto de Conferências sobre as alianças entre neoliberalismo e autoritarismo na política contemporânea, da iminente crise sanitária, econômica e humanitária que estava por vir com o Covid-19. © 2020, Revista de Filosofia: Aurora. All Rights Reserved.

9.
Revista De Administracao Publica ; 54(5):1402-1416, 2020.
Article in English | Web of Science | ID: covidwho-978954

ABSTRACT

This study aims to highlight the efforts made by the Brazilian Courts of Accounts (CAs) during the COVID-19 pandemic to collaborate with its jurisdictional authorities, civil servants, and society to face its effects. Descriptive and qualitative research was carried out, analyzing the legislation issued by the CAs to evaluate their actions. Among the findings, it was observed that the CM took administrative and pedagogical measures to protect the public, such as the suspension or restriction of face-to-face service. Also, the courts suspended collective events, face-to-face meetings, and travel, adopted telework, limited expenditures and distance learning courses. Among the procedural measures, Plenary Sessions or Chambers, procedural deadlines, and remittance of accounts were suspended. Finally, the activities of guidance and monitoring were conducted under a series of guidelines and recommendations created collaboratively with other agencies and branches of government, guiding public spending, the acquisition and contracting of services with no bidding requirements, among other procedures. It is concluded that the set of measures implemented by the CAs shows a change in the traditional status of subsequent control of public accounts - which gives rise to punitive action - for prior and concurrent control, with recommendations, inspections, and monitoring, when the manager still has instruments to amend errors and avoid waste and misapplication of public resources.

10.
Clinical Nutrition ESPEN ; 40:509-510, 2020.
Article in English | EMBASE | ID: covidwho-942962

ABSTRACT

Rationale: COVID-19 is a rapidly evolving pandemic with many critically ill patients and no proven treatments except supportive care. Further, cytokine storm and hyperinflammatory state appears to be an emerging component of severe COVID-19 illness. There are few data about nutritional therapy interventions for COVID-19 critically ill patients. Methods: This study included a retrospective, single-center case series of 51 consecutively critically ill patients who received enteral feeding with confirmed COVID-19 at Hospital Israelita Albert Einstein in São Paulo, Brazil. We collected and analyzed demographic, nutritional parameters, and nutritional therapy data. We expressed the measurement data as mean ± standard deviation. Results: Of the 51 critically ill patients with COVID-19, the mean age was 66 years old (SD ± 14) and 37 (73%) were men;34 (66 %) are overweight or obese. It was observed a mean of 1.2g/Kg (SD ± 0.3) actual body weight protein delivered and mean of 21.3 Kcal/Kg (SD ± 4.2) actual body weight calories delivered. Despite a good tolerance to enteral nutritional therapy, 22% had diarrhea and 20% vomiting. The length of stay in the ICU was 18 (SD ± 11) days on average and 14 (27%) died. Conclusion: Nutritional therapy in covid-19 patients is still a new topic. Apparently, patients have good tolerance to enteral nutrition and it is possible to achieve nutritional goals. Disclosure of Interest: None declared

11.
Clinical Nutrition ESPEN ; 40:509, 2020.
Article in English | EMBASE | ID: covidwho-942961

ABSTRACT

Rationale: Overfeeding in critically ill patients is associated with many complications. Propofol provide non-nutritional calories, potentially causing overfeeding. Patients with COVID-19 in the ICU need a large amount of sedation and Propofol is one of the most widely used drug. Methods: We retrospectively studied 51 adult mechanically ventilated intensive care unit (ICU) patients with COVID-19 receiving enteral nutrition. We collected and analyzed demographic, nutritional parameters, and dosage of Propofol used. Descriptive data were reported as means and s.d. or median and interquartile range (IQR) in case of skewed distributions, frequencies and percentages or ranges (minimum–maximum). Results: Of the 51 critically ill patients with COVID-19, 76% of patients received propofol during hospitalization. The mean age was 66 years old (SD ± 14) and 37 (73%) were men;34 (66 %) are overweight or obese. An adequacy of 88% and 86% of protein and energy goals, respectively, were achieved. Among patients with propofol (N = 39) administration, median intake from propofol was 260 (IQR 20-594) kcal. The proportion of calories from propofol was 15% (SD± 8) and mean duration of use was 8 days (SD± 5.5). The length of stay in the ICU was 18 (SD ± 11) days on average and 14 (27%) died. Conclusion: The mean proportion of non-nutritional calories in patients who receive propofol is low. However, it can reach more than 500 kcal/ day in some patients. Patients must have close monitoring in order to prevent overfeeding. Disclosure of Interest: None declared

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