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1.
European Psychiatry ; 65(Supplement 1):S543-S544, 2022.
Article in English | EMBASE | ID: covidwho-2154113

ABSTRACT

Introduction: Hypochondria is characterized by the presence, for 6 months or more, of a generalized and non-delusional concern with fear of having (or the idea that one has) a serious illness, based on the wrong interpretation of the symptoms. In somatic-type delusional disorder, the delusional idea is fixed, indisputable, and occurs intensely because the patient is fully convinced of the physical nature of the disorder. Objective(s): To describe a clinical case and make a differential diagnosis of hypochondriac disorder vs somatic-type delusional disorder. Method(s): Case report: 61-year-old woman, after suffering from COVID-19, develops a hypochondriacal disorder vs. somatic delusional disorder, presenting anxiety-depressive symptoms and digestive somatic complaints, with a loss of 15 kg of weight. She made frequent visits to doctors and multiple complementary tests discarding organicity. She required involuntary hospital admission for 48 days, and pharmacological treatment with Venlafaxine 150 mg, Olanzapine 5mg, Mirtazapine 30mg and Alprazolam 1mg. The patient presented slow evolution during admission, with ups and downs and stagnation, meriting enteral nutrition due to refusal to ingest, given abdominal kinesthetic hallucinations and digestive evaluation (EDS) with a result of antral gastritis and negative H. pylori. In subsequent follow-ups after partial remission of symptoms, obsessive personality traits are glimpsed, although with better personal functioning. Result(s): The diagnosis at discharge was inconclusive, however the data points to a somatic-type delusional disorder. Conclusion(s): The influence of COVID-19 as a triggering factor, social isolation and premorbid personality traits, influence the development of a Somatic Delusional Disorder vs Hypochondriac Disorder, regarding this case.

2.
Journal of the American Society of Nephrology ; 33:794, 2022.
Article in English | EMBASE | ID: covidwho-2125825

ABSTRACT

Background: Severe presentation of ANCA vasculitis is a life-threatening disease despite aggressive immunodepression therapy. Complement hyperactivation is involved in pathogenesis;thus, the effect of the C5 inhibitor (eculizumab) used in severe forms of ANCA vasculitis may be a treatment option. Method(s): This is a retrospective study. Nine patients were included. Period of study: from May 2017 to May 2022. All patients received at least 3 drugs (steroids, rituximab and mycophenolate or cyclophosphamide) before eculizumab. Eculizumab was indicated as an off-label indication due to lack of improvement or clinical worsening. Result(s): Mean (SD) age: 62 (15) years. Female: 4. Three patients showed serum antiproteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA) and 5 (myeloperoxidase: MPO-ANCA) and one was ANCA-negative. Six patients had an estimated glomerular filtration rate (eGFR) < 10 ml/min/1.73 m2 at presentation. Five patients had pulmonary involvement. The mean (min-max) time of follow-up after the onset of eculizumab was 27 (1-60) months. One patient ANCA-negative microscopic polyangiitis with diffuse alveolar hemorrhage needed orotracheal intubation and had a satisfactory evolution after eculizumab;however, 20 days after, the patient developed a COVID-19 infection and died. One patient who needed urgent dialysis at presentation did not recover renal function and showed a complement factor H mutation. The evolution of the other 7 patients was as follows: the median (p25-p75) eGFR increased from baseline to the end of the follow-up: 9.1(4.8-21.7)ml/min/1.73m2 to 31(13-45)ml/min/1.73m2, respectively (P=0.018) and the mild proteinuria disappeared in all patients. Alveolar hemorrhage improved in all patients within seven days after the first eculizumab administration. The median (p25-p75) doses of eculizumab administered were 1800(1800-3600) mg. One patient required eculizumab for two different periods. Conclusion(s): One patient died due to a COVID-19 infection, and one remained in chronic renal replacement therapy. Alveolar hemorrhage was well controlled in all patients. The eGFR increased significantly in 7/9 patients, and in 4/6 patients, dialysis could be withdrawn. In severe ANCA vasculitis, eculizumab should be considered for improving outcomes.

6.
Dance/Movement Therapy for Trauma Survivors: Theoretical, Clinical, and Cultural Perspectives ; : 24-39, 2022.
Article in English | Scopus | ID: covidwho-2080703

ABSTRACT

The authors engaged with each other to share their own experiences, memories, personal trauma, identities, and cultural backgrounds, and embody a necessary reflection and dialogue around their racial/culturally diverse backgrounds during these trauma-filled times. The emotional, social, political, and spiritual impact of the COVID-19 pandemic, the civil unrest due to the continued violence against BIPOC (Black, Indigenous, People of Color) bodies, and the persistence of systemic racism, oppression, and white supremacy drove the necessary questioning on how to support those from marginalized identities both from a theoretical stance and a social action stance. The authors’ reflections on their own growing edge and positionality led them to assess integrated therapeutic approaches that move in the direction of healing historical wounds that continue to deny our humanities. Groundwork in dance/movement therapy (DMT) education and pedagogy, the application of embodied intersectionality approaches, and implementation of culturally/spiritually informed practices were offered as frameworks for the continued creation of equitable, safe, and accountable spaces in our DMT field. The chapter includes a summary of culturally and trauma-informed DMT therapeutic guiding principles that were useful in the authors’ own journeys toward becoming agents of change for themselves and for those they serve. © 2022 selection and editorial matter, Rebekka Dieterich-Hartwell and Anne Margrethe Melsom.

7.
European psychiatry : the journal of the Association of European Psychiatrists ; 65(Suppl 1):S543-S544, 2022.
Article in English | EuropePMC | ID: covidwho-2072721

ABSTRACT

Introduction Hypochondria is characterized by the presence, for 6 months or more, of a generalized and non-delusional concern with fear of having (or the idea that one has) a serious illness, based on the wrong interpretation of the symptoms. In somatic-type delusional disorder, the delusional idea is fixed, indisputable, and occurs intensely because the patient is fully convinced of the physical nature of the disorder. Objectives To describe a clinical case and make a differential diagnosis of hypochondriac disorder vs somatic-type delusional disorder. Methods Case report: 61-year-old woman, after suffering from COVID-19, develops a hypochondriacal disorder vs. somatic delusional disorder, presenting anxiety-depressive symptoms and digestive somatic complaints, with a loss of 15 kg of weight. She made frequent visits to doctors and multiple complementary tests discarding organicity. She required involuntary hospital admission for 48 days, and pharmacological treatment with Venlafaxine 150 mg, Olanzapine 5mg, Mirtazapine 30mg and Alprazolam 1mg. The patient presented slow evolution during admission, with ups and downs and stagnation, meriting enteral nutrition due to refusal to ingest, given abdominal kinesthetic hallucinations and digestive evaluation (EDS) with a result of antral gastritis and negative H. pylori. In subsequent follow-ups after partial remission of symptoms, obsessive personality traits are glimpsed, although with better personal functioning. Results The diagnosis at discharge was inconclusive, however the data points to a somatic-type delusional disorder. Conclusions The influence of COVID-19 as a triggering factor, social isolation and premorbid personality traits, influence the development of a Somatic Delusional Disorder vs Hypochondriac Disorder, regarding this case. Disclosure No significant relationships.

8.
2022 Ieee Mexican International Conference on Computer Science (Enc) ; 2022.
Article in Spanish | Web of Science | ID: covidwho-2068320

ABSTRACT

In recent years the application of deep learning algorithms in the subdomain of audio analysis has grown rapidly, however it is a topic that can be complex for students and researchers who have a first approach and want to develop an application in this field. The use of deep learning techniques applied to audio signals has allowed the development of a wide variety of useful tools in our daily lives, from virtual assistants to medical applications. This article presents a literature review of the main techniques that have been used in recent years for analysis, feature extraction and classification from audio spectra or spectrograms, as well as examples of application in the context of the COVID-19 pandemic in which multiple related projects have emerged, such as diagnostic systems. The techniques addressed are recurrent neural networks (RNN), convolutional neural networks (CNN) and generative adversarial networks (GAN). It is intended that the reader will be able to acquire this knowledge from a simple perspective and that this information will be useful in their research or development.

10.
Journal of Clinical Oncology ; 40(16), 2022.
Article in English | EMBASE | ID: covidwho-2009536

ABSTRACT

Background: The COVID-19 pandemic has led to disruptions in cancer treatment delivery among breast cancer patients in the U.S. However, it is currently unknown whether racial/ethnic disparities exist in cancer treatment disruptions among patients with breast cancer and SARS-CoV-2 infection. Methods: We obtained data from the ASCO Survey on COVID-19 in Oncology Registry (March 2020-July 2021) describing breast cancer patients diagnosed with SARS-CoV-2 during their care treated at 46 practices across the US. Data included patient demographics, SARS-CoV-2 diagnosis and treatment, breast cancer characteristics, and modifications to cancer treatment plans. Breast cancer treatment delay or discontinuation (TDD) was defined as any treatment postponed more than two weeks from the originally scheduled date. We computed adjusted odds ratios (aOR) using multivariable logistic regression, accounting for non-independence of patients within hospitals to evaluate racial/ethnic disparities of TDD. Multivariable models were adjusted for age, sex, number of comorbidities, cancer extent, ECOG performance score, pandemic period based on case peaks (< 06/2020, 06-12/2020, 01-07/2021), and COVID-19 severity (death/hospitalization/ICU admission/mechanical ventilation). Results: Breast cancer patients (n = 804) with SARS-CoV-2 were mostly aged 50 years and above (75%) and urban residents (83%). The racial/ethnic makeup of the sample included: 13.3% non-Hispanic Black/African American (NH-Black), 11.7% Hispanic/Latinx, 4.9% American Indian/Alaskan Native (NH-AI/ AN), 4.6% NH-Asian, and 65% NH-White. At SARS-CoV-2 diagnosis, 736 patients (91%) were scheduled to receive drug-based therapy (78%), radiation therapy (8%), or surgery (6%), of whom 39% experienced TDD. Across treatment modalities, the most commonly reported TDD reason from the clinic perspective was the patient's COVID-19 disease (∼90%). Overall, NH-Black (62%), Hispanic/Latinx (44%), and NH-Asian (42%) adults with breast cancer and SARS-CoV-2 were more likely to experience TDD versus NH-White adults (34%) (p < 0.001). In multivariable analyses, NH-Black cancer patients were more likely to experience TDD compared to NH-White patients (aOR: 3.12, 95% CI: 1.96-5.47). The data suggest Hispanic/Latinx (aOR: 1.34, 95% CI: 0.78-2.30) breast cancer patients may also experience TDD, although not statistically significant. No association was observed among NH-Asian (aOR: 1.16, 95% CI: 0.50-2.73) or NH-AI/AN (aOR: 0.64, 95% CI: 0.28-1.52) breast cancer patients with TDD. Conclusions: Black or African American breast cancer patients are more likely to experience cancer care disruptions during the pandemic. Future research should evaluate the long-term impacts of care disruptions on breast cancer outcomes among minoritized US communities.

11.
Journal of Clinical Oncology ; 40(16), 2022.
Article in English | EMBASE | ID: covidwho-2009535

ABSTRACT

Background: U.S. rural cancer patients experience multifactorial barriers to cancer treatment;however, little is known about the impact of the pandemic on cancer treatment delays or discontinuations (TDD) in the rural context. Our objective was to evaluate the role of rurality at both the patient and clinic level on cancer TDD among patients living with cancer with SARS-CoV-2 infection. Methods: We used data from the ASCO Survey on COVID-19 in Oncology Registry (March 2020-July 2021), which includes cancer patients diagnosed with SARS-CoV-2 (n = 3193). Data included patient demographics, SARSCoV- 2 treatment, cancer characteristics, and modifications to cancer treatment plans. Cancer-related TDD was defined as any treatment postponed > two weeks from the original scheduled date. Rurality was defined using the USDA Rural-Urban Commuting Area schema. We compared cancer characteristics, COVID-19 outcomes, and TDD by rurality of cancer patients, and TDD by rurality of oncology practices. We computed adjusted odds ratios (aOR) using multivariable logistic regression to evaluate rurality with TDD adjusting for age, race/ethnicity, sex, comorbidities, ECOG score, cancer extent, pandemic time period based on case peaks (< 06/2020, 06-12/2020, 01-07/2021), and COVID-19 severity. Results: Rural cancer patients (n = 499, 16%) with SARS-CoV-2 were mostly over 50 years (87%), female (57%), and NH-White (81%) with solid tumors (76%). Most rural patients received oncology treatment in urban areas (65%, p < 0.001). Rural patients were less likely to receive care through telemedicine (18%) compared to urban patients (26%) (p < 0.001). At SARS-CoV-2 diagnosis, rural patients were scheduled to receive drug-based therapy (72%), radiation therapy (8%), surgery (4%), or transplant (1%). Rural versus urban cancer patients with SARS-CoV-2 were less likely to experience TDD (41% vs. 51%) (p < 0.001). Among patients treated at rural oncology clinics, urban cancer patients were more likely to experience TDD (65%) compared with rural patients (47%) (p < 0.001). Similarly, among patients treated at urban oncology clinics, urban cancer patients were also more likely to experience TDD (51%) compared with rural patients (38%) (p < 0.001). In multivariable analyses, rural cancer patients were 28% less likely to experience TDD (aOR:0.72, 95% CI: 0.55- 0.94) than urban cancer patients. Oncology practice rurality was not associated with TDD (aOR: 1.19, 95% CI: 0.81-1.76). Conclusions: Rural cancer patients were less likely to experience TDD than urban patients supporting the urban-rural paradox i.e., geographic distance to cancer care facilities is not consistently associated with treatment delivery in expected ways. Future work should focus on area-level factors of the rural cancer patient experience to disentangle potential reasons for TDD during the pandemic.

12.
Cancer Research ; 82(12), 2022.
Article in English | EMBASE | ID: covidwho-1986487

ABSTRACT

Background: Due to societal factors in the US, racial/ethnic minority adults are disproportionately impacted by the COVID-19 pandemic, particularly those with existing comorbid conditions such as cancer. It is currently unknown whether disparities exist in cancer treatment delivery among racial/ethnic minority patients with cancer and SARS-CoV-2. Methods: Data were obtained from the ASCO COVID-19 and Cancer Registry (March 2020-July 2021), including data from cancer patients diagnosed with SARS-CoV-2 during their care (n=3193) at 60 practices across the US. Data included patient demographics, SARS-CoV-2 diagnosis and treatment, cancer clinical characteristics, and modifications to cancer treatment plans. Cancer treatment delay or discontinuation (TDD) was defined as any treatment postponed more than two weeks from the original scheduled date. We descriptively evaluated demographic and clinical characteristics, compared disparities in TDD by race/ethnicity and urban/rural residency, and evaluated reasons for TDD as reported by the clinics. We computed adjusted odds ratios (aOR) using multivariable logistic regression, accounting for non-independence of patients within hospitals to evaluate racial/ethnic disparities of TDD. Multivariable models were adjusted for age, sex, body mass index, number of comorbidities, cancer type, cancer extent, cancer status at SARS-CoV-2 diagnosis (progressing/stable) and SARS-CoV-2 severity (death/hospitalization/ICU admission/mechanical ventilation). Results: Cancer patients with SARS-CoV-2were mostly female (57%), urban residents (84%), and NH-White (66%);49% were 65+ years old. Most patients had solid tumors (75%). At SARS-CoV-2 diagnosis, 2403 patients (76%) were scheduled to receive drug-based therapy (69%), radiation therapy (7%), surgery (4%), or transplant (0.7%), of whom 49% experienced TDD. The most reported TDD reason from the clinic perspective was the patient's COVID-19 disease (90%). Overall, NH-Black (64%) and Hispanic (57%) with SARS-CoV-2 were more likely to experience TDD versus NH-White adults (46%) (p<0.001). This disparity was also observed across urban residing adults (p<0.001). Among rural adults, NH-AI/AN (75%) and NH-Black (61%) were more likely to experience TDD versus NH-White patients (39%). In multivariable analyses, disparities persisted, by NH-Black cancer patients with 92% (aOR:1.92, 95% CI:1.24-2.96) and Hispanic patients with 41% (aOR:1.41, 95% CI:1.03-1.91) higher odds of experiencing TDD. We observed consistent results among urban and rural subgroups. Conclusion: Racial/ethnic disparities exist in TDD among cancer patients with SARS-CoV-2 in urban and rural care settings. Future studies should evaluate the impacts of delays to cancer treatment delivery on cancer outcomes among minoritized communities in the US.

13.
INTERNET JOURNAL OF ALLIED HEALTH SCIENCES AND PRACTICE ; 20(2), 2022.
Article in English | Web of Science | ID: covidwho-1935140

ABSTRACT

Purpose: Legislation was created for NCAA Divisions I, II, and III to guarantee an independent medical care administrative structure designed to give "unchallengeable autonomous authority" regarding diagnosis, management, and return to play decisions to primary athletics health care providers (physicians and athletic trainers). The purpose of this project was to 1) explore the structure of athletic health care in NCAA athletic institutions as it relates to independent medical care, and 2) describe changes in those structures that have occurred as a result of the COVID-19 pandemic. Methods: We used a cross-Sectional Study. Setting: College/University. In 2017, 162 supervising athletic trainers responded to our survey. Variables collected included health care delivery model, AHCA selection, decision making and injury reporting structure, confidence in independent medical care, COVID-19 response involvement, changes due to COVID-19. Results: The overall demographic characteristics indicated that most supervising athletic trainers were male (117/162, 72.2%), 48 +/- 10 y old, and have been at the institution for a significant tenure 15 +/- 11y. In 2020, responses from 174 supervising athletic trainers were recorded in the survey. The majority of respondents were male (108/174, 62.1%). Average age of the population was 45 +/- 11y with 22 +/- 10y of experience and 15 +/- 10y of experience at their current institution The athletics health care model is most common across all NCAA Divisions (n=163 80.7%). Average confidence was rated 4.54 +/- 0.67. Results indicate a significant increase in confidence from 2017 to 2020 that patient care decisions are independent of influence. The majority of supervising athletic trainers indicated that they were involved in COVID-19 response (n=190, 94.1%) Conclusions: More NCAA Institutions should transition to a medical model of health care delivery to ensure independent medical care. Athletic trainers were used in the policy creation and implementation of COVID-19 protocols for their institutions and athletics programs.

14.
Current Psychology ; : 15, 2022.
Article in English | Web of Science | ID: covidwho-1926083

ABSTRACT

This study assesses the relationship between COVID-19 anxiety and subjective well-being in terms of the mediating role of COVID-19 preventive behaviors. Additionally, the contribution of sociodemographic factors (sex and age) and risk perception on COVID-19 anxiety and its potential measurement invariance was tested in 5655 participants from 12 countries in Latin America and the Caribbean. A mixture of both latent and observable variables were analyzed using a system of structural equations. The Coronavirus Anxiety Scale (CAS), Preventive COVID-19 Infection Behaviors Scale (PCIBS) and single-item measures were used to assess the perceived probability of death, perceived severity and concern about transmitting COVID-19. The results indicated that there is a significant and relevant direct effect of COVID-19 anxiety on participants' well-being. Furthermore, COVID-19 anxiety significantly predicted both preventive behavior (beta = .29, p < .01) and well-being (beta = -.32, p < .01). The effects of COVID anxiety and preventive behavior explained 9.8% of the variance in well-being (R-square = .098);whereas, 8.4% of the variance in preventive behavior was associated with COVID anxiety (R-square = .084). Likewise, perceived likelihood of death from COVID, perceived severity of COVID, and concerns about COVID transmission were positively related to anxiety. Age was negatively related to anxiety, with men being less anxious than women. The results are invariant by country, i.e., the broad relationships found in the combined sample are also present in each individual country. The findings indicate that, although the exact relationships between variables may vary between countries, there are enough similarities to provide useful information about the impact of the COVID-19 pandemic in each of the countries included in the study.

15.
Nephrology Dialysis Transplantation ; 37(SUPPL 3):i699-i700, 2022.
Article in English | EMBASE | ID: covidwho-1915793

ABSTRACT

BACKGROUND AND AIMS: Transplantation (KTx) is considered the best renal replacement therapy nephrologists can offer and improving its outcomes remains a primary challenge in our field. KTx ureteral JJ stenting has been used to prevent urological complications, but there is no consensus about its elective removal timing and literature regarding routine US imaging after EJJR to detect complications is lacking. Our aim was to define the incidence of urological complications diagnosed by routine US after EJJR in KTx, determine US utility and best time interval to perform it. METHOD: We retrospectively analyzed all routine KTx US performed in our Unit from 2016 until 2020 by an experienced interventional nephrologist. US post EJJR findings were compared with previous patient US. KTx characteristics, treatment and outcomes were recorded. RESULTS: • 345 KTx were done in the study period, 62.9% of receptors were male, 81.7% had a first KTx and 91.5% of organs were from a deceased donor. No routine US post EJJR was done in 20.9% due to the COVID pandemic. • Mean timing to elective JJ stent removal was 36.4 ± 25 days (SD). • Mean time from EJJR to US was 16.3 ± 28.8 days (SD). • Urinary tract (UT) ectasia (19.7%) and grade I UT dilatation (3.6%) were not considered pathological. • 47.3% (129) had a complication detected: 88.4% (114) had a collection, 8.5% (11) had UTD: 5.4% grade II and 3.1% grade III. 3% had other complications. • Table1 summarizes the outcomes of complications detected • Cumulative frequency analysis of complications post EJJR showed the highest diagnostic yield was around day 10 post removal (Figure 1). CONCLUSION: Routine US after EJJR allowed a timely diagnosis and early treatment of urological complications, a key factor for successful transplantation. KTx US is a cost-effective and reproducible test that provides crucial information to guide clinical decisions, being most efficient when performed 10 days post elective removal. Interventional nephrologists could do this examination promptly. (Table Presented).

16.
Nephrology Dialysis Transplantation ; 37(SUPPL 3):i516-i517, 2022.
Article in English | EMBASE | ID: covidwho-1915740

ABSTRACT

BACKGROUND AND AIMS: The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) pandemic has had a massive impact in health systems worldwide, taking an important toll on dialysis patients as they are more comorbid, have higher mortality and an impaired immune system. Vaccines against SARS-Cov-2 proved to reduce mortality and hospitalization, but serological response in the dialysis population is weaker. Therefore, predictors of response would be useful to assess their level of protection and evaluate the need for further booster doses of the vaccine. METHOD:-We retrospectively analysed all peritoneal dialysis (PD) patients fully vaccinated (two doses) in our PD Unit between February and June 2021.-Clinical data, vaccine brand and anti SARS-Cov-2 IgG antibodies (Ab) measured by enzyme immunoassay were recorded.-The linear correlation between Ab level and all other variables was analysed using the Pearson correlation coefficient. RESULTS:-In the study period, 22 of 32 prevalent patients were fully vaccinated with two vaccine doses, 70.8% Moderna, 20.8% Pfizer/BioNTech and 8.3% AstraZeneca. A total of 50% were male and 36.4% had diabetes mellitus, with mean age 61.4 ± 12.3 years. Median time on PD was 15.6 months (IQR 4.9-25.1). Up to 22.7% were on immunosuppression (IS) after a kidney graft dysfunction (prednisolone, tacrolimus or both) and 22.7% had a previous diagnosis of coronavirus disease (COVID).-A total of 072.7% had an immediate minor adverse event after the second dose of the vaccine, mostly headache/malaise (31.8%) and puncture site pain (22.7%).-Ab levels were significantly higher in those patients with previous COVID (r = 0.452;P = 0.035). Male gender and Moderna vaccine had a positive correlation with higher Ab titers, although not statistically significant (r = 0.401, P = 0.064 and r = 0.215, P = 0.337, respectively). Those with longer duration of PD treatment before vaccination had a weaker serological response (r = -0.228, P = 0.307). Ab levels did not correlate with age (r = -0.046, P = 0.837), diabetes (r = -0.121, P = 0.600) or IS medications (r = -0.070, P = 0.756).-Shows Ab levels at 7.4 ± 4 weeks after the second dose: CONCLUSION: In our experience, PD patients have an adequate serological response to the SARS-Cov-2 vaccines, being previous COVID exposure the main predictor of a good response. Conversely, longer duration of PD treatment was a prognostic factor of seroconversion failure. We believe this should be kept in mind to assess the need for booster vaccination doses in those patients.

18.
19.
Diamond and Related Materials ; : 109093, 2022.
Article in English | ScienceDirect | ID: covidwho-1850932

ABSTRACT

Graphene-based materials present a high surface area and can present several structural defects or heteroatoms depending on the fabrication method. Such properties facilitate the graphene interaction with biomolecules leading to high electrochemical activity. In this context, we synthesize a high-quality dispersed reduced graphene oxide using Lysozyme as a dispersant (Ly-RGO). In this study, we have investigated the graphite oxidation-reduction fabrication process using X-ray Photoelectron Spectroscopy, X-ray Diffraction, and Raman Spectroscopy. We have used the Ly-RGO to fabricate an electrode on an electrochemical cell in which voltammograms show significant transduction of electrical signals. Finally, cyclic voltammetry and chronoamperometry measurements were performed with human saliva and SARS-CoV-2 RNA samples, to calibrate our biosensor. The results indicate that Ly-RGO has great potential in biosensor devices.

20.
RISTI - Revista Iberica de Sistemas e Tecnologias de Informacao ; 2021(E45):501-514, 2021.
Article in Spanish | Scopus | ID: covidwho-1823797

ABSTRACT

This study is developed within the framework of the changes brought about by the Covid-19 pandemic and social distancing in the educational field. The educational institutions closed their doors, being the technological mediation the key factor to give continuity to the classes. However, certain pedagogical / andragogical practices are not coupled to the technological context, which makes a harmonic pedagogical / andragogical orientation necessary with the use of technology based on the social constructivist paradigm of knowledge. Through a bibliometric analysis, the best positioned and most cited articles on issues of technology, pedagogy, andragogy and constructivism in Scopus are explored. In this way, the structured discussion between the authors analyzes results to recognize traits and concurrent variables in said studies. The conclusions of this first step offer us new horizons for pedagogy / andragogy with a techno-pedagogical constructivist approach. © 2021, Associacao Iberica de Sistemas e Tecnologias de Informacao. All rights reserved.

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