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Clin Dermatol ; 40(5):573-585, 2022.
Article in English | PubMed | ID: covidwho-2158592


The current coronavirus disease 2019 pandemic has exceeded any epidemiologic prevision, but increasing information suggests some analogies with the major viral outbreaks in the last century, and a general warning has been issued on the possibility that coinfections can make the differential diagnosis and treatment difficult, especially in tropical countries. Some reports have noted that the presence of high dengue antibodies can give a false-negative result when testing for severe acute respiratory syndrome coronavirus 2. Mucocutaneous manifestations are very frequent, with an apparent overlap among different pathogens. However, strong clinicopathologic correlation might provide some clues to address differentials. Waiting for laboratory and instrumental results, the timing and distribution of skin lesions is often pathognomonic. Histopathologic findings characterize certain reaction patterns and provide insights on pathogenetic mechanisms. Unfortunately, skin assessment, especially invasive examinations such as biopsy, takes a back seat in severely ill patients. A literature retrieval was performed to collect information from other epidemics to counteract what has become the most frightening disease of our time.

J Eur Acad Dermatol Venereol ; 35(9): 1742-1743, 2021 09.
Article in English | MEDLINE | ID: covidwho-1367331
Dermatologic Therapy ; 33(4), 2020.
Article in English | GIM | ID: covidwho-1343849


During the COVID-19 pandemic in Italy, our Dermatology Clinic experienced an increased number of consultations for contact dermatitis, and skin injuries, requested by the colleagues and sanitary personnel of other wards, often sending images by smart phones applications to avoid visits in presence. The most affected sites included the nasal bridge, hands, cheek, periocular, and perioral regions. Dryness, itching, but also stinging sensations were common. Although majority of PPE related manifestations were mild, self-healing when the use was stopped for sufficient time, restand recovery was not always viable in current situation. The critical point is that adherence to strict PPE protocol is paramount, and presence of even mild abrasion, itching, or burning sensation might induce inadvertent protocol breaches, such as mask touching and PPE adjustment. For mild face dermatitis,we prescribed the application of moisturizers on intact skin and topical antibiotic ointment, mainly fusidic acid on super-infected skin. For sustained contact dermatitis, low- to medium-potency not fluorinated topical glucocorticoids were allowed. Hand and sometimes feet maceration were relieved with normal saline hydropathic compress and topical use of zinc oxide ointment. When erosion and exudation occurred, the application of topical glucocorticoid cream was added. Sustained dermatosis, worsening of preexisting diseases such as psoriasis or atopic dermatitis or allergic reactions might require more complex assessment and management, including the temporary removal from work for health care personnel.