Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 37
Filter
Add filters

Document Type
Year range
1.
European journal of public health ; JOUR(Suppl 3), 32.
Article in English | EuropePMC | ID: covidwho-2101763

ABSTRACT

Background During the COVID-19 pandemic, several professional athletes from different sports were infected by SARS-CoV-2. The aim of this systematic review was to evaluate the currently available scientific evidence regarding the cardiological, pulmonary, psychological, and combined sequelae, in professional athletes. Methods The present systematic review was performed following the PRISMA statements, thereby searching on 3 databases: PubMed, ISI Web of Science, Scopus. Primary studies published between January 2020 and March 2022, investigating symptomatic and instrumental sequelae in competitive athletes after COVID-19 infection, were included. Results A total of 1,957 articles were screened, finally 18 were included (6 cohort studies, 2 case-control studies and 10 cross-sectional studies). Studies’ sample size ranged from a minimum of 12 to 1908 athletes playing different sports. In addition, the studies examined the following type of sequelae: 12 cardiological, 2 psychological, 1 pulmonary and 3 combined. Regarding the cardiological field, the prevalence of anomalies in instrumental examinations ranged 0-27.89% for first level tests (echocardiography, electrocardiogram, troponin), and 0-6.21% for second level tests (cardiac magnetic resonance). The prevalence of myocarditis and pericarditis in the athletes ranged from 0 to 3.33%, whereby the prevalence of myocarditis was in the range 0-2.32% and that of pericarditis in the range 0-2.22%. Conclusions The results show that post SARS-CoV-2 infection cardiac sequelae have a quite low prevalence among competitive athletes included in our review, but it would be important to set up a gradual and continuous testing approach to preserve sports performance. Public health framework, such as vaccination campaign, is important both at European and international level in order to address potential consequences of infectious diseases among competitive athletes. Key messages • It is important to monitor all COVID-19 sequelae in European competitive athletes playing different sports. • Considering anti-COVID-19 vaccination in competitive athletes as an important preventive measure, to limit the circulation of the virus and the physical consequences that may occur.

2.
European journal of public health ; JOUR(Suppl 3), 32.
Article in English | EuropePMC | ID: covidwho-2101498

ABSTRACT

Background Evaluating COVID-19 vaccine coverage and risk factors is useful to develop public health strategies against COVID-19 pandemic. In the framework of two studies commissioned by the European Centre for Disease Prevention and Control (ECDC) and coordinated by Epiconcept, France, we reported findings about incidence and seroprevalence among healthcare workers (HCWs) enrolled from three Italian hospitals. Methods From July 2021 to date, the AOUP “G. Rodolico-San Marco” (Catania), the San Gerardo Hospital (Monza) and the Policlinico Gemelli (Rome) participated in the ECDC study to measure COVID-19 vaccine effectiveness. Catania and Rome also participated to the ECDC study of nosocomial transmission. HCWs were asked to complete a weekly questionnaire to report changes in health status and professional/personal exposures. At recruitment, a nasopharyngeal swab for RT-PCR and a blood sample for serology test were collected. Moreover, HCWs were followed-up with a weekly or bimonthly nasopharyngeal or saliva swabs. Blood samples were collected every one or two months. Results A total of 226 HCWs was enrolled from Catania, 330 from Rome and 132 from Monza in the COVID-19 vaccine effectiveness study. As of February 2022, PCR tests performed were 2270 in Catania, 5475 in Rome and 891 in Monza sites. Moreover, the serological tests performed were 845 in Catania, 760 in Rome and 395 in Monza sites. A total of 6 SARS-CoV-2 infections were identified in Catania, 34 in Rome and 4 in Monza sites. Interestingly, the study of nosocomial transmission reported the highest incidence rate in Catania (4 per 10,000 person-day), while 0.7 per 10,000 person-day in Rome. During the study period seroprevalence declined by 17% among HWCs enrolled in Catania. Conclusions Our findings revealed low number of COVID-19 infections, with high COVID-19 vaccine coverage among HCWs. However, further analyses are needed to provide more robust estimates of vaccine effectiveness. Key messages Monitoring risk factors is useful to understand the pandemic scenario among high-risk groups. A larger sample size and follow-up will improve public health vaccination strategies against COVID-19.

3.
Roczniki Humanistyczne ; JOUR(8):77-94, 70.
Article in French | Scopus | ID: covidwho-2091158

ABSTRACT

The COVID-19 pandemic has represented a fundamental ‘discursive moment’ (Moirand) in recent decades;in particular, this event has put to the test the shared concepts of ‘scientific truth’ (Charaudeau) and ‘expertise’ (Vicari). This period has also been marked by unprecedented activity in the popularisation of specialised concepts, linked to the fields of medicine and biology, and also to the fields of economics and social life, notably through media channels (press, radio, television, the Internet and social networks). The explanation of highly technical notions, as well as of new terms resulting from the pandemic, has often taken various forms, among which defining strategies play a major role. Our contribution aims to highlight the framing function that metaphor can play when it is used as an instrument to define a scientific concept (Rossi). To this end, we analyse a corpus of the French and Italian press from 2020 and 2021, detecting the metaphors used to define the reformulations of concepts related to the pandemic. © 2022 Towarzystwo Naukowe KUL. All Rights Reserved.

4.
2022 IEEE International Conference on Digital Health, ICDH 2022 ; : 117-122, 2022.
Article in English | Scopus | ID: covidwho-2051994

ABSTRACT

The presence of SARS-CoV-2 RNA in wastewaters was demonstrated early into the COVID-19 pandemic. Data on the presence of SARS-CoV-2 in urban wastewater can be exploited for different aims, including: i) description of outbreaks trends, ii) early warning system for new COVID-19 outbreaks or for the spread of the virus in new territories, iii) study of SARS-Co V-2 genetic diversity and detection of its variants, and iv) estimating the prevalence of COVID-19 infections. Therefore, wastewater surveillance (known as Wastewater Based Epidemiology, WBE) can be a powerful tool to support the decision-making process on public health measures. Italy was among the first EU countries investigating the occurrence and concentration of SARS-Co V-2 RNA in urban wastewaters, virus detection being accomplished at an early phase of the epidemic, between February and May 2020 in north and central Italy. The present study reports on the methodological issues, related to sample data collection and management, encountered in establishing the systematic, wastewater-based SARS-CoV-2 surveillance, and describes the results of the first six months of surveillance. © 2022 IEEE.

5.
European psychiatry : the journal of the Association of European Psychiatrists ; 64(Suppl 1):S311-S311, 2021.
Article in English | EuropePMC | ID: covidwho-2045216

ABSTRACT

Introduction Although some philosophers recognize in the loneliness an evolutionary existential process, a 2019 declaration of World Health Organization underlines the major health problem in the worldwide is the perception of state of loneliness. The feeling of loneliness linked to the social isolation (SI) or a lack of social opportunity activate a stressful condition associated to an increase of social dependence. This ‘learned social helplessness’ can be dangerous so that it is associated with an increased prevalence of suicides (Cacioppo and Cacioppo, 2018;Bzdok and Dunbar, 2020). Considering the impact of loneliness on the mental health we can assume that the COVID-19 forced SI affects the state of health and psychosocial well-being. Objectives To evaluate the psychosocial impact of the SI in Italy. Methods An ad hoc survey have been sent from May to June 2020. Results These results refer to the Italian survey of a multicenter investigation with partnership of Spain and Portugal universities. The investigation is in progress being a longitudinal study. Of the total 292 subjects investigated (age xM: 34;sD14.13), 118 (40,41%) had been in SI. Subjects forced into SI report more interference in the life satisfaction (p=0.003) though no more anxiety, depression and hostility we found in the SI group. Conclusions During the phase 2 of Italian COVID-19 diffusion, we found an impact on the life satisfaction more than psychopathology. We can assume that the impact of mental health it may occur as the reduction in life satisfaction associated with forced SI continues.

6.
Psychosomatic Medicine ; 84(5):A60, 2022.
Article in English | EMBASE | ID: covidwho-2003181

ABSTRACT

Sexual and gender minority (SGM) people face pre-existing inequalities that may have been exacerbated by the Coronavirus-19 (COVID-19) pandemic. Canadian sexual minorities are twice as likely to live alone compared to heterosexual people and are more vulnerable to anxiety, depression, self-harm, and substance abuse. Despite these vulnerabilities, several studies suggest that social support and community solidarity can mitigate the effect of stress on SGM mental health. Using a cross-sectional online survey, our team examined SGM and cisgender heterosexual mental health and social support during the first four months of the COVID-19 crisis in Quebec, Canada. A total of 2900 adults (n = 304 SGM people, n = 2596 cisgender heterosexual people) completed questionnaires measuring perceived social support, perceived stress, depressive symptoms, anxiety symptoms, and loneliness. A series of one-way ANOVAs revealed that SGM people presented worse health outcomes than cisgender heterosexual people on all questionnaires (p < .001). Post hoc analyses also showed that some particularly marginalised SGM sub-groups, including bisexual and asexual people, showed the worst health outcomes. Moderation analyses later revealed that social support moderated the relationship between perceived stress and depressive symptoms among both SGM and cisgender heterosexual people - but this effect was four times stronger among SGM people (ΔR2 = .041;p < .001) than among cisgender heterosexual people (ΔR2 = .010;p < .001). These results suggest fostering social connectedness among SGM people may be especially beneficial in buffering against distress in the face of a crisis. To better understand how SGM mental health is evolving during this pandemic, our team is currently conducting a follow-up longitudinal study examining mental health, trauma, coping strategies and resilience among SGM and cisgender heterosexual adults before and after vaccination efforts started in Canada (to date, N = 6083). Preliminary results from time 1 (July 2020) and 2 (Fall 2021) are being treated and will also be presented.

7.
Journal of General Internal Medicine ; 37:S527, 2022.
Article in English | EMBASE | ID: covidwho-1995663

ABSTRACT

CASE: A 78-year-old female with a history of recurrent nephrolithiasis and left ureteral reconstruction presented to our institution with hematuria, flank pain, anorexia and weight loss. 3-4 months prior, she had similar symptoms in her home country and was treated with multiple courses of antibiotics. She attempted to present to the US for evaluation earlier, but was unable to due to COVID. She first presented to a nearby US hospital and was diagnosed with an atrophic kidney with a superimposed infection based on imaging and labs. An EGD/ Colonoscopy done for her weight loss was unrevealing. She was discharged on antibiotics and told to follow up for possible nephrectomy. 1 days later, she presented to our institution with continued symptoms. Repeat CT was concerning for emphysematous pyelonephritis. Vital signs were unremarkable. Labs showed no leukocytosis, normal creatinine, hypercalcemia to 13.0 and urinalysis showed hematuria, pyuria and proteinuria. She was initially treated with IV antibiotics and a percutaneous nephrostomy for source control. To continue work up for her weight loss, a CT chest was done that showed multiple lung nodules and a re-review of the CT abdomen noted a T12 lytic lesion. 2 weeks into her admission, she had a left nephrectomy. Pathology revealed an invasive, grade 3, poorly differentiated squamous cell carcinoma arising from the renal pelvis, with lymphovascular invasion. A biopsy of the T12 lesion was consistent with metastasis. Due to her functional status and aggressive nature of her malignancy, palliative therapies were recommended. Patient's course was further complicated by ileus, massive aspiration and spinal cord compression from the T12 lesion. She passed away on hospital day 45. IMPACT/DISCUSSION: Squamous cell carcinoma of the renal pelvis is a rare malignancy. Most present at an advanced stage with a long history of nonspecific symptoms, such as hematuria and/or flank pain, which are typically attributed to recurrent nephrolithiasis;one of the most well-documented risk factors. Additionally, there are no characteristic findings on imaging, making radiological differentiation between renal SCC and other chronic infectious processes difficult. Often there is no suspicion for malignancy until the pathology results. For these reasons, renal SCC should be considered in patients who have underlying risk factors. One may also benefit from a renal biopsy, which can be done before a nephrectomy and has been shown to have a high degree of diagnostic accuracy. Adding to this diagnostic challenge, our patient's care was delayed due to COVID, demonstrating the importance of considering alternative diagnoses when patients have deferred presentations and fractured workups. CONCLUSION: Consider the diagnosis of renal SCC in patients with recurrent nephrolithiasis, UTIs, unexplained hematuria and/or flank pain and refer for a renal biopsy if appropriate. Be mindful of the impact of fragmented and delayed medical care on vulnerable patients.

8.
Neural Regeneration Research ; 18(2):284-288, 2023.
Article in English | MEDLINE | ID: covidwho-1964240

ABSTRACT

In the last two years, a new severe acute respiratory syndrome coronavirus (SARS-CoV) infection has spread worldwide leading to the death of millions. Vaccination represents the key factor in the global strategy against this pandemic, but it also poses several problems, especially for vulnerable people such as patients with multiple sclerosis. In this review, we have briefly summarized the main findings of the safety, efficacy, and acceptability of Coronavirus Disease 2019 (COVID-19) vaccination for multiple sclerosis patients. Although the acceptability of COVID-19 vaccines has progressively increased in the last year, a small but significant part of patients with multiple sclerosis still has relevant concerns about vaccination that make them hesitant about receiving the COVID-19 vaccine. Overall, available data suggest that the COVID-19 vaccination is safe and effective in multiple sclerosis patients, even though some pharmacological treatments such as anti-CD20 therapies or sphingosine l-phosphate receptor modulators can reduce the immune response to vaccination. Accordingly, COVID-19 vaccination should be strongly recommended for people with multiple sclerosis and, in patients treated with anti-CD20 therapies and sphingosine l-phosphate receptor modulators, and clinicians should evaluate the appropriate timing for vaccine administration. Further studies are necessary to understand the role of cellular immunity in COVID-19 vaccination and the possible usefulness of booster jabs. On the other hand, it is mandatory to learn more about the reasons why people refuse vaccination. This would help to design a more effective communication campaign aimed at increasing vaccination coverage among vulnerable people.

10.
Ieee Journal of Selected Topics in Signal Processing ; 16(2):208-223, 2022.
Article in English | English Web of Science | ID: covidwho-1883127

ABSTRACT

Social distancing and temperature screening have been widely employed to counteract the COVID-19 pandemic, sparking great interest from academia, industry and public administrations worldwide. While most solutions have dealt with these aspects separately, their combination would greatly benefit the continuous monitoring of public spaces and help trigger effective countermeasures. This work presents milliTRACE-IR, a joint mmWave radar and infrared imaging sensing system performing unobtrusive and privacy preserving human body temperature screening and contact tracing in indoor spaces. milliTRACE-IR combines, via a robust sensor fusion approach, mmWave radars and infrared thermal cameras. It achieves fully automated measurement of distancing and body temperature, by jointly tracking the subjects's faces in the thermal camera image plane and the human motion in the radar reference system. Moreover, milliTRACE-IR performs contact tracing: a person with high body temperature is reliably detected by the thermal camera sensor and subsequently traced across a large indoor area in a non-invasive way by the radars. When entering a new room, a subject is re-identified among several other individuals by computing gait-related features from the radar reflections through a deep neural network and using a weighted extreme learning machine as the final re-identification tool. Experimental results, obtained from a real implementation of milliTRACE-IR, demonstrate decimeter-level accuracy in distance/trajectory estimation, inter-personal distance estimation (effective for subjects getting as close as 0.2 m), and accurate temperature monitoring (max. errors of 0.5 degrees C). Furthermore, milliTRACE-IR provides contact tracing through highly accurate (95%) person re-identification, in less than 20 seconds.

11.
10th World Conference on Information Systems and Technologies, WorldCIST 2022 ; 468 LNNS:542-552, 2022.
Article in English | Scopus | ID: covidwho-1872332

ABSTRACT

The COVID-19 health crisis has forced many people to work from home, exposing companies and workers to the various risks brought about by teleworking. In order to raise awareness and enable better management of these risks, we have built an ontology for the control and mitigation of teleworking risks as well as a tool for self-assessment of individual worker risk profiles. We have conducted a literature review and interviews about corporate practices to manage telework’s negative impacts. The resulting ontology allows us to link the risks with adaptations provided by the employers and employees. In order to circulate this self-assessment tool, we have integrated the ontology into a user-friendly website, where people can fill out an anonymous survey to establish their personal risk profile and get recommendations about further adaptations that could be beneficial in their situation. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

12.
Sci Total Environ ; 837: 155767, 2022 Sep 01.
Article in English | MEDLINE | ID: covidwho-1821477

ABSTRACT

The SARS-CoV-2 Omicron variant emerged in South Africa in November 2021, and has later been identified worldwide, raising serious concerns. A real-time RT-PCR assay was designed for the rapid screening of the Omicron variant, targeting characteristic mutations of the spike gene. The assay was used to test 737 sewage samples collected throughout Italy (19/21 Regions) between 11 November and 25 December 2021, with the aim of assessing the spread of the Omicron variant in the country. Positive samples were also tested with a real-time RT-PCR developed by the European Commission, Joint Research Centre (JRC), and through nested RT-PCR followed by Sanger sequencing. Overall, 115 samples tested positive for Omicron SARS-CoV-2 variant. The first occurrence was detected on 7 December, in Veneto, North Italy. Later on, the variant spread extremely fast in three weeks, with prevalence of positive wastewater samples rising from 1.0% (1/104 samples) in the week 5-11 December, to 17.5% (25/143 samples) in the week 12-18, to 65.9% (89/135 samples) in the week 19-25, in line with the increase in cases of infection with the Omicron variant observed during December in Italy. Similarly, the number of Regions/Autonomous Provinces in which the variant was detected increased from one in the first week, to 11 in the second, and to 17 in the last one. The presence of the Omicron variant was confirmed by the JRC real-time RT-PCR in 79.1% (91/115) of the positive samples, and by Sanger sequencing in 66% (64/97) of PCR amplicons. In conclusion, we designed an RT-qPCR assay capable to detect the Omicron variant, which can be successfully used for the purpose of wastewater-based epidemiology. We also described the history of the introduction and diffusion of the Omicron variant in the Italian population and territory, confirming the effectiveness of sewage monitoring as a powerful surveillance tool.


Subject(s)
COVID-19 , SARS-CoV-2 , COVID-19/epidemiology , Humans , RNA, Viral , SARS-CoV-2/genetics , Sewage , Waste Water/analysis , Wastewater-Based Epidemiological Monitoring
13.
ESMO Open ; 7(3): 100499, 2022 06.
Article in English | MEDLINE | ID: covidwho-1821235

ABSTRACT

BACKGROUND: ESMO COVID-19 and CAncer REgistry (ESMO-CoCARE) is an international collaborative registry-based, cohort study gathering real-world data from Europe, Asia/Oceania and Africa on the natural history, management and outcomes of patients with cancer infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). PATIENTS AND METHODS: ESMO-CoCARE captures information on patients with solid/haematological malignancies, diagnosed with coronavirus disease 2019 (COVID-19). Data collected since June 2020 include demographics, comorbidities, laboratory measurements, cancer characteristics, COVID-19 clinical features, management and outcome. Parameters influencing COVID-19 severity/recovery were investigated as well as factors associated with overall survival (OS) upon SARS-CoV-2 infection. RESULTS: This analysis includes 1626 patients from 20 countries (87% from 24 European, 7% from 5 North African, 6% from 8 Asian/Oceanian centres), with COVID-19 diagnosis from January 2020 to May 2021. Median age was 64 years, with 52% of female, 57% of cancer stage III/IV and 65% receiving active cancer treatment. Nearly 64% patients required hospitalization due to COVID-19 diagnosis, with 11% receiving intensive care. In multivariable analysis, male sex, older age, Eastern Cooperative Oncology Group (ECOG) performance status ≥2, body mass index (BMI) <25 kg/m2, presence of comorbidities, symptomatic disease, as well as haematological malignancies, active/progressive cancer, neutrophil-to-lymphocyte ratio (NLR) ≥6 and OnCovid Inflammatory Score ≤40 were associated with COVID-19 severity (i.e. severe/moderate disease requiring hospitalization). About 98% of patients with mild COVID-19 recovered, as opposed to 71% with severe/moderate disease. Advanced cancer stage was an additional adverse prognostic factor for recovery. At data cut-off, and with median follow-up of 3 months, the COVID-19-related death rate was 24.5% (297/1212), with 380 deaths recorded in total. Almost all factors associated with COVID-19 severity, except for BMI and NLR, were also predictive of inferior OS, along with smoking and non-Asian ethnicity. CONCLUSIONS: Selected patient and cancer characteristics related to sex, ethnicity, poor fitness, comorbidities, inflammation and active malignancy predict for severe/moderate disease and adverse outcomes from COVID-19 in patients with cancer.


Subject(s)
COVID-19 , Hematologic Neoplasms , Neoplasms , COVID-19 Testing , Cohort Studies , Female , Humans , Male , Middle Aged , Neoplasms/epidemiology , Neoplasms/therapy , Registries , SARS-CoV-2
14.
J Eur Acad Dermatol Venereol ; 36(8): 1292-1299, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-1807159

ABSTRACT

BACKGROUND: Moderate-to-severe atopic dermatitis (AD) in the adolescence is a high burden disease, and its treatment can be very challenging due to paucity of approved systemic drugs for this age and their side-effects. Dupilumab was recently approved for treatment of adolescent AD. OBJECTIVES: A multicentre, prospective, real-world study on the effectiveness and safety of dupilumab in adolescents (aged from ≥12 to <18 years) with moderate-to-severe AD was conducted. The main AD clinical phenotypes were also examined. METHODS: Data of adolescents with moderate-to-severe AD treated with dupilumab at label dosage for 16 weeks were collected. Treatment outcome was assessed by EASI, NRS itch, NRS sleep loss and CDLQI scores at baseline and after 16 weeks of treatment. The clinical scores were also evaluated according to clinical phenotypes. RESULTS: One hundred and thirty-nine adolescents were enrolled in the study. Flexural eczema and head and neck eczema were the most frequent clinical phenotypes, followed by hand eczema and portrait-like dermatitis. Coexistence of more than 1 phenotype was documented in 126/139 (88.5%) adolescents. Three patients (2.1%) contracted asymptomatic SARS-CoV-2 infection and 1 of the discontinued dupilumab treatment before the target treatment period. A significant improvement in EASI, NRS itch, NRS sleep loss and CDLQI was observed after 16 weeks of treatment with dupilumab. This outcome was better than that observed in clinical trials. Dupilumab resulted effective in all AD phenotypes, especially in diffuse eczema. Twenty-eight (20.1%) patients reported adverse events, conjunctivitis and flushing being the most frequent. None of patients discontinued dupilumab due to adverse event. CONCLUSIONS: Dupilumab in adolescent AD showed excellent effectiveness at week 16 with consistent improvement of all clinical scores. Moreover, dupilumab showed a good safety profile also in this COVID-19 pandemic era.


Subject(s)
COVID-19 , Dermatitis, Atopic , Eczema , Antibodies, Monoclonal, Humanized , COVID-19/drug therapy , Dermatitis, Atopic/drug therapy , Double-Blind Method , Humans , Pandemics , Prospective Studies , Pruritus , SARS-CoV-2 , Severity of Illness Index , Treatment Outcome
15.
Argumentation Library ; 43:125-144, 2022.
Article in English | Scopus | ID: covidwho-1750499

ABSTRACT

Doubt is a double-edge sword. On the one hand, uncertainty is essential for epistemic progress, and yet, doubt can also make us vulnerable to deception, confused to the point of no longer knowing what is true. What distinguishes a doubt that is epistemologically beneficial from one which is deceptive, or even manufactured in the context of a conspiracy theory? In this chapter, we explore doubt, its role, and the way it is being handled in the context of the public controversy about the COVID-19 vaccine. We approach conspiracy theories as argumentative discourses and reconstruct the generic structure of a conspiracy theory macro argument. Through the structure, we look into the discourse of the twelve prominent anti-vaxxers known as the “Disinformation Dozen”, focusing on the argumentative potential that doubt can have in the public controversy about the COVID-19 vaccine. We suggest to distinguish ambivalence from scepticism and denialism as three argumentative potentials that a motivated doubt can have. We argue that ambivalent doubt ought to be acknowledged, addressed and incorporated into the public health narrative, in order to avoid that an unnecessarily broad interpretation of conspiracy theory dominates the public debate and leaves an uncertain public a prey to it. © 2022, The Author(s).

16.
Digestive and Liver Disease ; 54:S14, 2022.
Article in English | EMBASE | ID: covidwho-1734330

ABSTRACT

Background and aims: Solid organ transplant recipients (SOTRs) have been considered as an extremely vulnerable population in respect to SARS-CoV-2 infection. We aimed to assess the incidence and lethality rate of SARS-CoV-2 infection in different organ transplant settings using the liver as a comparator. Methods: In this nationwide population-based study we compared the crude incidence and lethality rates of SARS-CoV-2 infection [95% Bonferroni adjusted CI (Ba-CI)] among Italian LTRs as compared to non-liver SOTRs and to general population. The following independent groups had been compared: Italian general population, all SOTRs, liver transplant recipients (LTRs) and non-Liver SOTRs in area with different incidence of infection. Incidence rate ratio (IRR) and lethality rate ratio (LRR) was assessed. Community risk exposures in transplant settings were assessed. Results: From February 21 to June 22, 2020, there were 450 cases of SARS-CoV-2 infections over 14168 LTRs (n=89) and 29815 non-liver SOTRs (n= 361). A significantly lower risk of infection [IRR 0.56 (Ba-CI 0.34-0.92), 0.45 (Ba-CI 0.26-0.79), 0.52 (Ba-CI 0.36-0.75)] and a lower lethality rate ratio [(LRR 0.61 (Ba-CI 0.23-1.57), 0.37 (0.08-1.76), 0.52 (0.23-1.18] was found among LTRs as compared to non-liver SOTRs in the three areas. Excluding Lombardy, the risk of infection and lethality in LTRs was lower compared to general population. Non-Liver SOTRs showed an increased risk of infection and lethality at all geographic levels compared to general population. No significant difference in the adherence to mitigation policies was found. Conclusions: Liver transplantation was associated with a significantly lower risk of SARS-CoV-2 infection and lethality in respect to non-liver solid organ transplants. A separate evaluation of organ-specific risk stratification analysis and vaccination responses in transplant population is needed.

17.
Safety and Health at Work ; 13:S162, 2022.
Article in English | EMBASE | ID: covidwho-1677022

ABSTRACT

Introduction: During the pandemic, the use of personal protective equipment (PPE) has become essential for Healthcare Workers (HCWs) to fight safely against the virus. However, the extensive and prolonged use of PPE may cause various adverse skin reactions due to the use of alcohol hand cleanser and protracted use of masks and goggles. The aim of this study is to evaluate the skin problems caused by PPE in HCWs and the possible consequences on their work. Materials and methods: An online ad hoc questionnaire, composed by 35 questions about sociodemographic characteristics, work related issues and exposure/habits about PPE, was administered to a sample of Italian HCWs. Univariate and multivariate analyses were performed in order to explore possible associations between variables. Results: We tested 3 types of PPE: Gloves, Hair Bonnets and Masks for different time of utilization (<1, 1-3, 3-6, >6 hours). The sample included 1184 participants: 292 workers reported a dermatological pathology nested in four different pathological groups: 45 (15%) had Psoriasis, 54 (19%) Eczema, 38 (13%) Acne, 48 (16%), seborrheic dermatitis and 107 (36%) other. 25 workers had a loss of occupational days due to dermatological illness;56 occupational physician surveillance visits were asked for;in 30 cases were recognized limitations in working duties. Conclusions: Protecting HCWs requires the use of PPE, but occupational dermatitis is an emerging problem in the midst of the COVID-19 pandemic. National data for affected healthcare professionals could contribute to a better understanding of the problem and prevention initiatives in the workplace

18.
Journal of E-Learning and Knowledge Society ; 17(2):32-44, 2021.
Article in English | Scopus | ID: covidwho-1622967

ABSTRACT

This work analyzes the teaching and educational approach, based on Distance Learning, used in a Mathematics class with Engineering students. Thinking critically about how we worked before the COVID-19 crisis, we try to elaborate on possible ways to overcome linear processes' inertia. The teacher's educational activities and the students’ reactions are analyzed in the light of the theory of Transformative Learning. We adopt the theoretical and analytical tools provided by the theory of Interest Dense Situation and the theory of Self-Determination. A qualitative and quantitative analysis was conducted referring to a didactic experiment monitoring various elements through a questionnaire consisting of open-ended and Likert questions and thought closed questions together with the results of the midterm test. © Italian e-Learning Association.

19.
JACCP Journal of the American College of Clinical Pharmacy ; 4(12):1631-1632, 2021.
Article in English | EMBASE | ID: covidwho-1615982

ABSTRACT

Introduction: The CDC recommends that all adults 65 and over receive the pneumococcal polysaccharide vaccine (PPSV23) once and the influenza vaccine yearly. These vaccines are often administered during in-office visits with primary care physicians (PCP) however, since many of these visits occurred using telemedicine due to the COVID-19 pandemic, the opportunity to receive these vaccinations may have been impacted. Research Question or Hypothesis: To compare the rate of yearly influenza and pneumonia vaccine for adults 65-years and older in 2020 to the three years prior (2017, 2018, and 2019). Study Design: Single-center, retrospective chart review from January 2017 through December 2020. Methods: PPSV23 and influenza vaccine data was collected via the electronic medical record. All adults > 65-years old with a PCP within the group were included. Adults with a documented allergy to either vaccine were excluded. Descriptive statistics were used to present the rates of these vaccines in each year included. Results: There were 2,168 PPSV23 administered in 2020, 2,164 administered in 2019, 1,847 administered in 2018, and 1,976 administered in 2017. In 2020, 12.25% of newly eligible patients were vaccinated by the end of the calendar year. In the 3 years prior, an average of 5.51% of newly eligible patients were vaccinated by the end of the calendar year. There were 3,619 influenza vaccines administered in 2020, 3,746 vaccines administered in 2019, 5,898 vaccines administered in 2018, and 5,926 vaccines administered in 2017. There was a total of 1,346 individuals who received an influenza vaccine in 2020 who did not receive one in the 3 years prior. Conclusion: When compared to previous years, the rate of PPSV23 increased and the rate of influenza vaccinations decreased. These results may suggest that COVID-19 lead to more patients wanting protection against pneumonia and less patients wanting protection against influenza.

20.
2nd Workshop on Technology Enhanced Learning Environments for Blended Education - The Italian E-Learning Conference, teleXbe 2021 ; 3025, 2021.
Article in English | Scopus | ID: covidwho-1589769

ABSTRACT

Due to the health emergency caused by Covid-19, the educational activities have undergone a radical change. In fact, in the period between March and June 2020, all activities were carried out at a distance. The University of Foggia, in addition to the synchronous and asynchronous modes of teaching delivery, successfully tested in the academic year 2019/2020, has introduced, starting from the following academic year 2020/2021, a new mode of teaching delivery, called dual, with lessons delivered simultaneously in presence and at a distance, in line with the implementation of a gradual recovery plan. This has made it necessary, on the one hand, to carry out timely technological upgrading of existing facilities and, on the other hand, further training of the teaching staff: distance learning requires different professional skills, inspired by changing learning models and adaptable to the needs of the context. The pandemic experience, therefore, has not debased traditional didactics, but, rather, has led to the emergence of new needs, which require a redesign of the tools and resources in use. In the future, it will be necessary to reconsider the choice in favor of a completely face-to-face didactic and to prefer hybrid models capable of satisfying the needs of flexibility, accessibility and ubiquitous learning. © 2021 Copyright for this paper by its authors. Use permitted under Creative Commons License Attribution 4.0 International (CC BY 4.0).

SELECTION OF CITATIONS
SEARCH DETAIL