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1.
Revista Chilena De Infectologia ; 39(4):388-397, 2022.
Article in English | Web of Science | ID: covidwho-2307445

ABSTRACT

Background: Ventilator-associated pneumonia (VAP) is frequent in critical COVID-19 patients. Its early diagnosis is essential for its prognosis. Aim: To demonstrate the usefulness of the FilmArray Pneumo panel (FAP-P) in confirming or ruling out VAP in these patients. Methods: Retrospective study of 71 critical COVID-19 patients with suspected VAP in whom cultures and FAP-P were performed for diagnostic confirmation. Clinical characteristics, microbiology and mortality are described. The validity and safety of FAP-P is defined. Results: The use of FAP-P and cultures ruled out VAP in 29 patients (40.8%). In 41 patients, VAP was confirmed and the 30-day mortality was 48.8%. Forty-eight samples were studied, the cultures were positive in 30 (62.5%) and 33 bacteria were detected, FAP-P detected 32 of these 33 bacteria;37 bacteria were exclusively detected by PFA-P. The most prevalent bacteria were Klebsiella pneumoniae (31.4%), Pseudomonas aeruginosa (21.4%) and Acinetobacter calcoaceticus-baumannii (14.2%). The sensitivity, specificity, positive predictive value and negative predictive value of FAP-P with respect to cultures were 96.9%, 92.5%, 46.4% and 99.8%, respectively. One patient had VAP due to Burkholderia cepacia bacteria not detected by FAP-P. Conclusions: FAP-P is an effective molecular technique to rule out and diagnose VAP, allowing rapid suspension of antibiotics or early targeted treatment.

2.
European Respiratory Journal Conference: European Respiratory Society International Congress, ERS ; 60(Supplement 66), 2022.
Article in English | EMBASE | ID: covidwho-2253920

ABSTRACT

Introduction: Cognitive impairment is observed in patients for Covid-19;derived from both multiple organic dysfunctions due to the disease and its management during hospital stay. Existing literature reports greater cognitive impairment (60-80%) in patients with invasive mechanical ventilation (IMV), compared to those who did not require it (50-70%). Objective(s): To compare cognitive impairment among COVID-19 survivors with and without IMV during hospital stay. Method(s): A cross-sectional observational study was conducted. A total of 211 COVID-19 survivors participated, 64.9% required IMV (G1) and 35.1% did not (G2). The Montreal Cognitive Assessment (MOCA) was used to assess cognitive functions at a 9 month follow-up after hospital discharge. Statistical analyses were performed in SPSS V25. Result(s): Patients presented the following characteristics: male sex (G1: 61.8%, G2: 54.1%), and average age G1: 54.05+/-11.89, G2: 57.21+/-11.90 years. In both groups (G1 vs. G2) no significant differences (p<0.05) were found in the prevalence of probable mild cognitive impairment (72.3% vs. 82.4%), neither in the mean of principal affections reports: attention (4. 70+/-1.23 vs. 4.80+/-1.03) and memory (2.69+/-1.53 vs. 2.86+/-1.59). Orientation (5.60+/-.71 vs. 5.82+/-.41), was the only value that reached statistically significant differences (p=.013), but without clinical significance. Conclusion(s): Both groups have high prevalence of patients with probable mild cognitive impairment yet nine months after discharge, contrasting with the prevalence reported to patients with IMV and to the recovery time (3-6 months). Cognitive sequelae have a greater impact than reported in all patients regardless of treatment.

3.
European Respiratory Journal Conference: European Respiratory Society International Congress, ERS ; 60(Supplement 66), 2022.
Article in English | EMBASE | ID: covidwho-2251069

ABSTRACT

Introduction: More than 12% of COVID-19 hospitalized patients develop Generalized Anxiety Disorder (GAD) after discharged. High frequency band percentage of heart rate variability (hfHRV) is a reliable indicator of efficient functional coupling between autonomic branches across high-demanding adaptive situations. Objective(s): To compare hfHRV among post-hospitalized COVID-19 survivors by level of GAD. Method(s): We conducted an observational study with 211 post-COVID-19 participants (63.7% males;47.6y +/-14.3), 3 months after discharged. We registered their hfHRV with a computerized biofeedback equipment throughout four conditions: open-eyes (C1);closed-eyes (C2);closed-eyes+natural-relaxation (C3);and closed-eyes+deep-breathing (C4) (2.5 minutes per condition). Participants were classified into 3 categories using General Anxiety Disorder Scale (GAD-7): low anxiety (n=174, 67.5%, 47.2 yo +/-13.4;G1);moderate anxiety (n=24, 66.5%, 47.3 yo +/-15.3;G2) and severe anxiety (n=13, 60.5%, 46.1 yo +/-9;G3). Statistical analysis were performed with SPSS v28. Result(s): hfHRV percentage is higher at C3 in G1 (G1: 29.5 +/-21.1, G2: 21.1 +/-17.1, G3: 20.0 +/-20.4;p = 0.01). G3 display a 30% decrease in hfHRV during this condition in contrast with G1 (p = 0.006). Percentage of hfHRV in G1 (C1: 31 +/-22.6, C2: 29.2 +/-23.6, C4: 24.3 +/-20.7), and G3 (C1: 29.7 +/-22.8;C2: 27.9 +/-17.6;C4: 20 +/-20) didn't show any significant differences. Conclusion(s): C3 involve an adaptive challenge that demands an effective sympathetic-parasympathetic regulation. An increase in hfHRV during C3 in G1, indicates that the group with low anxiety exhibit a more effective psychophysiological adaptive feature than G2 and G3: a potential protective factor from GAD.

4.
European Respiratory Journal Conference: European Respiratory Society International Congress, ERS ; 60(Supplement 66), 2022.
Article in English | EMBASE | ID: covidwho-2269931

ABSTRACT

Background: The post-COVID syndrome generates physical and respiratory complications that can be accompanied by psychological impairments, which can affect long-term mental and physical health. Objective(s): Know the prevalence and severity of PTSD, anxiety, and depression in surviving COVID-19 patients in a follow-up evaluation. Method(s): A cross-sectional descriptive study was conducted. 227 survivors COVID-19 patients participated, were assessed three months following discharge hospital. The following questionnaires were used: The Brief Davidson Trauma Scale, the General Anxiety Disorder Questionnaire, and the Patient Health Questionnaire. A descriptive and statically analysis was performed using the statistical software SPSS version 26. Result(s): The 64.5% of the patients were men, 60.9% required of invasive mechanical ventilation (IMV) during the hospitalization, the average age was about 48.23+/-14.33 years old. The 40% of the patients showed symptoms associated with PTSD, 38.4% anxiety symptoms, 36.6% depression symptoms. There were statistically significant differences between the type of treatment during hospitalization (IMV vs without IMV), in PTSD (t=2.482, df=223, p=.014, XIMV = 5.21, XWIMV = 6.08) and anxiety (t= -2.006, df=223, p=.046, XIMV = 4.05, XWIMV =5.44). Conclusion(s): Survivors of COVID-19 experience a high prevalence of PTSD, anxiety, and depression even three months after discharge from hospital. Patients who did not require IMV during hospitalization experienced a high prevalence and severity of PTSD and anxiety symptoms. Screening for PTSD and other emotional disturbances should be considered in follow-up evaluations in patients discharged from the hospital.

5.
Archivos de Bronconeumologia ; 58(5):T379-T380, 2022.
Article in English, Spanish | EMBASE | ID: covidwho-2264766
6.
European Respiratory Journal Conference: European Respiratory Society International Congress, ERS ; 60(Supplement 66), 2022.
Article in English | EMBASE | ID: covidwho-2278744

ABSTRACT

Introduction: COVID-19 survivor patients report a complaint subjectively related to memory and attentionconcentration problems when carry out their daily activities. Objective(s): To investigate the presence of cognitive sequelae associated with COVID-19. Method(s): An observational cross-sectional study was conducted. Participated 229 COVID-19 survivor patients, who were evaluated with Montreal Cognitive Assessment (MoCA) and classified into three groups: a) severe cognitive impairment (G1, <13points, n=11), b) mild cognitive impairment (G2, 13-21 points, n=34), and c) without cognitive alterations (G3, 22-30 points, n=184). Statistical analyses were performed in SPSS V25. Result(s): Average age and male sex: G1: 67.36+/-10.71, 63.6%;G2: 58.76+/-11.55, 61.8%;G3: 53.32+/-11.39, 58.7%. G1 presented statistically differences (p <0.001) in all cognitive functions with the other groups (G1, G2, G3): visuospatial/executive ability (0.09+/-0.30, 0.53+/-0.50, 0.83+/-0.38), identification (2.00+/-0.89, 2.82+/-0.38, 2.92+/-0.32), attention (2.45+/-0.82, 3.97+/-1.16, 5.02+/-0.97), repetition (0.18+/-0.40, 0.29+/-0.46, 1.02+/-0.79), fluency (0.18+/-0.40, 0.68+/-0.47, 0.93+/-0.24), abstraction (0.18+/-0.40, 0.68+/-0.72, 1.41+/-0.77), deferred remembering (0.73+/-1.10, 1.44+/-1.37, 3.13+/-1.36) and orientation (4.64+/-0.92, 5.35+/-0.73, 5.79+/-0.49);except in executive ability, identification, repetition, abstraction and deferred remembering with respect to G2 (p<0.05). Conclusion(s): Cognitive alterations were found in patients post- COVID, especially in attention and deferred remembering, which could be related to errors of execution in other areas. In the case of the severe cognitive impairment, age may be a related variable. Necessary integrate this variable in the rehabilitation plan for a better prognosis and quality of life of patients.

7.
European Respiratory Journal Conference: European Respiratory Society International Congress, ERS ; 60(Supplement 66), 2022.
Article in English | EMBASE | ID: covidwho-2278743

ABSTRACT

Introduction: The presence of anxious, depressive and post-traumatic stress (PTSD) symptoms are the most reported psychological sequelae in post-COVID patients. The use of invasive mechanical ventilation (IMV) may contribute to the appearance of these symptoms. Objective(s): To know the differences in anxious, depressive, PTSD and fear of COVID symptoms among surviving COVID-19 patients with or without IMV, 3 months after hospital discharge. Method(s): An observational cross-sectional study was conducted. 239 surviving COVID-19 patients participated: 146 with IMV at hospitalization (67.80% men and 32.20% women) (G1) and 93 without IMV (61.29% men 38.70% women) (G2), who were evaluated with: GAD-7 for anxious symptomatology, PHQ-9 for depressive symptomatology, EMACOVID scale to measure fear of COVID-19, and the brief Davidson scale as screening for EPT. Statistical analyzes were performed in the statistical package SPSS V25. Result(s): Average age: G1= 48.62+/-13.62, G2= 48.49+/-15.43. There was a statistically significant difference in the EPT scores (G1: Md=4 [4.00-6.00];G2: Md=5 [4.00-7.00]). No statistically significant differences were found (P<0.05, G1 vs G2) in depression (Md=3 [0.00-6.00] vs Md=3 [0.00-8.50], anxiety (Md=2 [0.00-6.00] vs Md=3 [1:00-7:50]), nor fear of COVID (Md= 9 [7:00-15:00] vs Md=11.80 [7:00-14:00]), although there were clinical differences. Conclusion(s): Patients without IMV have a conscious experience of their hospitalization, which may lead to a higher level of PTSD compared to sedated patients with IMV.

8.
European Respiratory Journal Conference: European Respiratory Society International Congress, ERS ; 60(Supplement 66), 2022.
Article in English | EMBASE | ID: covidwho-2276054

ABSTRACT

Background: The cellular inflammation generated by SARS-COV-2 has been linked with different psychological impairments to long-term. The Mindfulness-based cognitive therapy can generate positive changes in these patients. Aim(s): To know the effects of a brief behavioural cognitive e-therapy on emotional symptoms, and cellular inflammation in COVID-19 survivors. Method(s): A quasi-experimental study was carried out. Participated two groups of survivors COVID-19 patients;experimental group (TG;4) and wait-list group (WLG;6). Both groups were evaluated using The General Anxiety Disorder Questionnaire, the Patient Health Questionnaire, and the brief Davidson Trauma Scale. Cellular inflammation was evaluated by an assessment of salivary IL-6 in a three-phase paradigm: baseline, stress, and recovery. The TG has received eight virtual mindfulness-based cognitive therapy sessions lasting two hours. The statistical analysis was performed using the software SPSS version 26. Result(s): The average age was about 58+/-11.57 years (TG), and 44.33+/- 17.18 years (WLG). The TG showed a only a clinical differences in the psychological symptoms (anxiety;Mepre = 15.50, Mepost = 8, depression;Mepre =13, Mepost =6 and PTSD;Mepre = 10, Mepost = 5.50), and in the il-6 levels (Base line Mepre = 7.11 pg/mL, Mepost = 16 pg/mL, stress phase Mepre = 10.07 pg/mL, Mepost = 8.77 pg/mL, and recovery phase Me = 14.08 pg/mL, Me = 16.29 pg/mL). Conclusion(s): This type of therapy can helps to reduce the levels of the emotional alterations and generate a modulation of the il-6 levels. The effects of this type of treatment need to continue in research as a therapeutic option for the population that survives COVID-19.

9.
Fisioterapia ; 45(1):45264.0, 2023.
Article in English | Scopus | ID: covidwho-2240564

ABSTRACT

Objective: To evaluate the association of psychosocial and work factors in the presence of job exhaustion in physiotherapists and respiratory therapists of a highly complex hospital in Bogotá, Colombia. Materials and methods: An analytical cross-sectional study. 31 physiotherapists and respiratory therapists from a high complexity hospital were surveyed. The data collection was carried out through a virtual questionnaire, it included psychosocial, demographic and labor variables;the prevalence of burnout was assessed using the Maslach Burnout Inventory for health professionals. Univariate and bivariate analyses were performed using SPSS version 25.0. Results: It was found that 93.5% (n = 29) corresponded to female, the mean age was 36±8.7 years old, with a type of fixed-term employment relationship of 96.8% (n = 30). Number of patients seen per shift of more than 15 patients in 38.7% (n = 12) of the cases. The 38.7% (n = 12) of the professionals presented job exhaustion, either due to emotional exhaustion, depersonalization, or low personal fulfillment. Finally, 64.5% (n = 20) and 74.2% (n = 23) considered that their mental or physical health has deteriorated due to working conditions given the current SARS-CoV-2 pandemic. Conclusion: A considerable percentage of professionals presented job exhaustion. Some psychosocial and working conditions are highlighted (insufficient staff, exhausting workday, lack of collaboration, loss of information) associated with the presence of burnout. There is deterioration in the physical and mental health of professionals due to the SARS-CoV-2 pandemic. © 2022 Asociación Española de Fisioterapeutas

10.
International Journal of Laboratory Hematology ; 45:185-185, 2023.
Article in English | Web of Science | ID: covidwho-2236504
11.
2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022 ; : 1443-1450, 2022.
Article in English | Scopus | ID: covidwho-2223075

ABSTRACT

The most recent Clinical Decision Support Systems use the potential of Machine Learning techniques to target clinical problems, avoiding the use of explicit rules. In this paper, a model to monitor and predict the risk of unfavourable evolution (UE) during hospitalization of COVID-19 patients is proposed. It combines Self Organizing Maps and local Naïve Bayes (NB) classifiers because of interpretation purposes. We used the results of six blood tests (leukocytes, D-dimer, among others) provided by a Spanish hospital group. The probabilistic approach allows us to get the daily risk of UE for each patient in an interpretable way. Several variants of the NB classifiers family have been explored, mainly weighting and likelihood estimation (parametric and nonparametric). Despite the over-simplified assumptions of the NB classifiers, they provided good predictive results in terms of sensitivity and specificity. The model with nonparametric likelihood estimation provided the best risk prediction over time even when designed with a limited number of samples. Specifically, the median value and interquartil range for the risk prediction were quite reliable even 10 days before the event day for patients hospitalized longer than 7 days. The risk median values also agree with the gold-standard for patients with a hospital stay shorter than 7 days, though the interquartil range can be too wide (probably because of the variability in the inpatient days - sometimes, just 2 days). Though a deepest analysis considering more patients and features would be convenient, our results show the potential of the proposed approach, both from a technical and clinical viewpoint. © 2022 IEEE.

12.
International Journal of Laboratory Hematology ; 45(Supplement 1):185, 2023.
Article in English | EMBASE | ID: covidwho-2219057

ABSTRACT

Introduction: Leukocyte differential, present certain features in SARS-CoV2 infected patients neutrophilia, lymphopenia and morphology alterations, which could be useful for screening. Cell population data (CPD) are reported as part of leukocyte differentials by Sysmex XN analyze;they are morphometric parameters that characterize neutrophils, lymphocytes and monocytes and classify them according to their volume, granularity and their content in nucleic acids. CPD reflects in numbers the changes in morphology and activation status triggered by infections. We aimed to evaluate the predictive power of CPDs for the differential diagnosis of COVID19 versus non-COVID19 pneumonia. Method(s): The prospective, observational, multicenter study was conducted in 3 hospitals, including patients > 18 years admitted with the diagnosis community-acquired pneumonia in the period November 2019 - October 2020. Complete blood count were analyzed using Sysmex XN counters. Diagnosis of SARS-CoV-2 infection was done using real-time reverse transcriptionpolymerase chain reaction. Patients were divided into two groups: (1) referral cohort in a hospital for the development of the model (2) the sample of two other hospitals for its validation. Multivariate logistic regression model has been developed for the detection of COVID patients. Robustness of the model has been evaluated by means of the area under the ROC curve and the calibration of the model. Statisticalsignificance p < 0.05. Result(s): 598 patients were recruited, 322 in the referral cohort and 276 in the validation group. The average age was 67.0 years (Standard Deviation 14.59 years ) and 61.49 % male. Neutrophil lymphocyte ratio, NE-WZ, LYY, LY-Z, LY-WX, LY- WY, MO- WY, MO-Z were included in the multivariate analysis, and presented a significant association for the differential diagnosis of SARS-CoV-2 infection with AUC of 0.84 (95% CI 0.82-0.92) in the referral cohort and 0.77 (0.69-0.85) in the validation cohort Conclusion(s): Leukocyte differential and CPDs could be very useful in the differential diagnosis of SARS-CoV-2 pneumonia and lead to a cheap and early diagnosis of the disease.

14.
Clinical Neurophysiology ; 141(Supplement):S120-S121, 2022.
Article in English | EMBASE | ID: covidwho-2177658

ABSTRACT

Introduction: Since the beginning of the pandemic caused by SARS-Cov-2, we have observed an increase of patients referred for electroneuromyography (ENMG) studies complaining of neuropathic symptoms, and who share in common having suffered from the disease by coronavirus (Covid-19), in its different forms of presentation. Clinical, diagnostic, and epidemiological studies that identify possible risk factors of peripheral neuropathies are needed. Method(s): Retrospective and prospective multicenter study in which neurophysiologists from 10 Andalusian hospitals are currently participating. The risk factors analyzed are age, sex, date of infection, date of onset symptoms in relation to Covid infection, hospital admission, admission to intensive unit care (IUC), time of admission, prone position, if orotracheal intubation needed, body mass index (BMI), personal history of interest, if previously vaccinated and complications. The observed peripheral nervous system involvement, caused both directly and indirectly by the virus, has been taken into account. Result(s): A total of 73 patients with neuropathic involvement. Of this total, 39 polyneuropathies (11 Guillain-Barre syndrome, 1 small fiber and 27 other critical illness polyneuropathies associated with IUC patients, 1 of these with associated myopathy), 13 peroneal neuropathies (4 unilateral, 1 with suprascapular neuropathy concomitant and 7 bilateral), 7 brachial plexopathies, 5 neuropathies of the superior laryngeal nerve (3 with concomitant involvement of the inferior) in patients with a history of orotracheal intubation, 2 neuropathies of the femorocutaneous nerve, 2 mononeuritis multiplex, 2 phrenic neuropathies, 1 vagus nerve neuropathy with no history of orotracheal intubation, 2 axillary neuropathies (1 with associated spinal neuropathy). Conclusion(s): Covid-19 causes involvement of the peripheral nervous system. Possible risk factors include male gender, old age, longer hospital stay, IUC admission, orotracheal intubation, prone position, suffering from previous pathologies, and high BMI. The possible causes that we consider for neuropathic involvement are compressive and positional (more indirectly related to the disease) and inflammatory / immune-mediated as the most direct cause of involvement caused by the SARS-Cov-2 virus. Knowledge of the risk factors is important, for the prevention, early diagnosis, and the correct treatment of these neuropathies. Some patients are left with serious neurological sequelae, with the consequences that this entails (high social and economic costs). Copyright © 2022

15.
Le Pharmacien Clinicien ; 57(4):e59, 2022.
Article in English | PubMed Central | ID: covidwho-2159678

ABSTRACT

Contexte: Au cours de la pandémie de SARS-CoV-2, au niveau national et international a été observée chez l'enfant, l'émergence d'une nouvelle forme d'inflammation systémique à tropisme cardiaque dénommée « PIMS » (paediatric inflammatory multisystem syndrome), présentant des signes cliniques comparables à ceux de la maladie de Kawasaki. La prise en charge médicamenteuse repose sur un traitement immunomodulateur composé d'immunoglobulines polyvalentes et de corticoïdes. Notre hôpital a été confronté à des pics d'afflux de patients atteints de PIMS, souvent en décalage de quelques semaines par rapport aux pics épidémiques. Objectifs: Comparer les caractéristiques et les traitements des populations pédiatriques prises en charge pour une maladie de Kawasaki ou PIMS afin de déterminer les principaux facteurs qui les différencient et mesurer l'impact des consommations en période de tension sur les approvisionnements. Patients et méthodes: Il s'agit d'une étude rétrospective sur la période de mars 2020 à octobre 2021. Les données ont été relevées à l'aide du dossier médical des patients afin de recueillir les critères suivants : caractéristiques anthropométriques, posologie des immunoglobulines (Ig), paramètres biologiques, examens complémentaires réalisés. Résultats: Le nombre de cas recensés de PIMS sur la période étudiée est de 58, ce qui représente 7,5 % de la cohorte nationale. Leur âge moyen était de 8,7 ans et les filles représentait 41,4 % des patients. Les patients atteints de Kawasaki sont plus jeunes (3,2 ans en moyenne). Quatre-vingt-six pour cent des patients PIMS ont eu un contact avec le SARS-CoV-2. Les patients atteints de maladie de Kawasaki ne présentaient pas de myocardite à l'échographie trans-thoracique contre 37,9 % chez les PIMS. La posologie moyenne était de 1,9 g/kg généralement répartie sur 2 jours, concernant les patients Kawasaki la dose était de 2 g/kg en 1 jour. La consommation d'immunoglobulines sur la période pour l'indication de PIMS était de 3,9 kg ce qui représente 3,8 % des consommations totales d'immunoglobulines de notre hôpital sur la période étudiée. On remarque aussi que la variation du nombre de diagnostics de PIMS est corrélée aux vagues épidémiques de SARS-CoV-2. Discussion/Conclusion: Ce travail nous permet de décrire la population de notre centre par rapport au données nationales désormais existantes et d'analyser l'utilisation des immunoglobulines polyvalentes dans une indication émergente et ce dans le contexte de fortes tensions d'approvisionnement. Les recommandations nationales voire internationales permettent d'encadrer la prise en charge de la population pédiatrique exposée à la pandémie. Ces données permettent d'alerter les tutelles afin de prendre en compte ces nouveaux besoins d'approvisionnement en immunoglobulines polyvalentes dans la priorisation des indications. Enfin, ces notions doivent être intégrées à la formation continue des pharmaciens y compris des internes en pharmacie intervenant notamment dans le contexte de la garde dans le cadre des validations de ces prescriptions puisque désormais les immunoglobulines IV font partie de l'arsenal thérapeutique des PIMS.

16.
Frontiers in Virtual Reality ; 3, 2022.
Article in English | Scopus | ID: covidwho-2142373

ABSTRACT

Introduction: Among the different psychological sequelae of post-COVID syndrome are symptoms related to emotional impairment, mostly depression, anxiety, and post-traumatic stress disorder (PTSD). Objective: To describe and compare the prevalence and severity of PTSD, anxiety, depression, and fear of COVID-19 in survivors 3 months after discharge from the hospital. Methods: A cross-sectional descriptive study was conducted, a total of 227 survivors of COVID-19 participated;they were assessed 3 months after being discharged from the hospital. A psychological evaluation focused on anxiety, depression, PTSD, and fear was conducted. Statistical analysis through the t-test for independent samples was performed. Results: Of the patients, 64.5% were men, 60.9% required invasive mechanical ventilation (IMV) during hospitalization, and the average age was about 48.23 ± 14.33 years. Also, 40% showed symptoms associated with PTSD, 38.4% exhibited anxiety, 36.6% depression, and 36.12% exhibited fear of COVID-19. There were statistically significant differences between men and women, in PTSD (t = -3.414, df = 224, p = 0.001, x̅m = 5.10, x̅w = 6.32), depression (t = -4.680, df = 225, p = 0.000, x̅m = 3.64, x̅w = 7.18), anxiety (t = -3.427, df = 152.53, p = 0.001, x̅m = 3.78, x̅w = 6.20), and fear of COVID-19 (t = -3.400, df = 224, p = 0.001, x̅m = 11.88, x̅w = 15.19). Furthermore, there were also statistically significant differences between the type of treatment during hospitalization (IMV vs. without IMV), in PTSD (t = 2.482, df = 223, p = 0.014, x̅IMV = 5.21, x̅WIMV = 6.08) and anxiety (t = -2.006, df = 223, p = 0.046, x̅IMV = 4.05, x̅WIMV = 5.44). Conclusion: Survivors of COVID-19 experience a high prevalence of PTSD, anxiety, depression, and fear, even 3 months after discharge from the hospital. Females and patients who did not require IMV during hospitalization are the most affected population, presenting more severe symptoms of these psychological alterations. More research is required to know and observe the long-term evolution of these psychological alterations in this population. Copyright © 2022 Luna-Rodríguez, Peláez-Hernández, Orea-Tejeda, Ledesma-Ruíz, Casarín-López, Rosas-Trujillo, Domínguez-Trejo and Tepepa-Flores.

17.
8th IEEE International Smart Cities Conference, ISC2 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2136382

ABSTRACT

Older adults face mobility and lifestyle challenges that limit their face-to-face interactions with the community. Technology used to communicate and access services has the potential to support older adults in overcoming some of these challenges;however, some older adults face difficulties in learning and using new technology. The necessity to overcome this barrier became more critical during the COVID-19 pandemic. This research team surveyed 74 older adults in El Paso, Texas, during the Summer of 2020 on aspects related to their use of technology. In this article, the authors report the survey findings on older adults' modes of communication, their purpose for using technology, their technology challenges, and ways they overcame technology challenges. These findings create opportunities to better understand how to use technology to foster the engagement of older adults with their community and empower them through the use of technology and Smart Cities solutions. © 2022 IEEE.

18.
8th IEEE International Smart Cities Conference, ISC2 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2136380

ABSTRACT

Older adults may struggle to maintain social connections as their lifestyles change, e.g., retirement. Their social connectedness can be fostered by using technology;however, many factors hinder older adults' technology use, creating a generational digital divide. This paper presents a study to learn about best practices for teaching and engaging older adults using technology. This study was done in the Summer and Fall of 2021 (during the COVID-19 pandemic) and consisted of an online survey, course observations, and focus groups with instructors. We found that a) older adults were often intrinsically motivated to take online courses;b) not having access to appropriate technology tools or infrastructure, and not having the knowledge or confidence needed to utilize technology created barriers that hinder older adults' participation in online courses;c) the instructors modified their courses to incorporate time to socialize, make classes more interactive, and refocus on the learning process rather than the outcomes;d) capitalizing on older adults' strengths and encouraging reciprocity was crucial for online learning;and e) there is a need to train instructors and students on the use of technology to teach and to learn online. This study's findings contribute to understanding how older adults learn with technology. Through technology engagement that facilitates learning, older adults may improve their quality of life and become empowered as critical agents in Smart Cities. © 2022 IEEE.

19.
Acta Colombiana de Cuidado Intensivo ; 22:S148-S156, 2022.
Article in English, Spanish | Scopus | ID: covidwho-2094957

ABSTRACT

In the midst the COVID-19 pandemic, and given the imminence of oxygen shortages in Colombia, the Knowledge Management and Transfer Network, made up of 19 scientific societies, health institutions, and universities, generates an update to the document led by the Colombian Association of Critical Medicine and includes new evidence-informed guidelines for the rational management of oxygen therapy, as well as basic and advanced devices for oxygen therapy. The recommendations refer to five topics: goal-oriented rational use of oxygen, standardization of follow-up and dose adjustment, effective use of oxygen therapy devices, rational use of invasive mechanical ventilation, and rational use of extracorporeal oxygenation membrane therapy. When exercising their judgment, it is expected that professionals and care teams will take into account these guidelines to make rational and safe use of oxygen therapy and its basic and advanced devices, together with the individual needs and preferences of the people who are under their care. © 2021 Asociación Colombiana de Medicina Crítica y Cuidado lntensivo

20.
Chest ; 162(4):A526, 2022.
Article in English | EMBASE | ID: covidwho-2060620

ABSTRACT

SESSION TITLE: COVID-19: Other Considerations in Management SESSION TYPE: Original Investigations PRESENTED ON: 10/18/2022 02:45 pm - 03:45 pm PURPOSE: In the context of COVID-19, dementia is a well-established risk factor for COVID-19 mortality compared to patients without dementia. To the date, however, there is limited understanding on how a preexisting dementia diagnosis may impact time to death following COVID-19 infection. Of note, identification of risk factors for earlier versus later mortality has the potential to influence treatment and hospice care decisions. Therefore, our aim was to investigate if Veterans with preexisting dementia experienced a longer time from COVID-19 diagnosis to death (all-cause mortality) compared to those without dementia who died of COVID-19. METHODS: We conducted a retrospective, cross-sectional chart review study utilizing data collected at the South Texas Veteran Health Care System from April 2020 to December 2021. Participants comprised deceased Veterans from all-cause mortality following COVID-19 infection, both with and without a preexisting dementia diagnosis in the 5 years prior to COVID-19 diagnosis. We conducted a univariate analysis of covariance, controlling for patient age, to investigate if days from COVID-19 diagnosis to death differed between patients with and without a preexisting dementia diagnosis. RESULTS: A total of N= 382 deceased subjects from all-cause mortality infected with COVID-19 were found in our data base, with a mean age of 73.74 years (SD = 12.33). The majority (64.65%;n = 247) did not have dementia, while 35 % (n = 135) had a preexisting dementia diagnosis in their medical record. Results indicated that number of days from COVID-19 diagnosis to death did not differ (F(1, 379) = 0.02, p = ns) between deceased subjects with dementia (M = 74.6 days, SD = 81.0) and without dementia (M = 75.6, SD = 93.6), controlling for patient age. Patient age was nonsignificant in the model (F(1,379) = 0.44, p = ns). CONCLUSIONS: Among patients deceased for all-cause mortality with COVID-19 infection, results did not indicate a significant difference in time to death following COVID-19 diagnosis between patients with preexisting dementia or without, controlling for age. Although dementia is an established risk factor for COVID-19 related death, it is likely one piece of a complex puzzle in terms of predicting earlier versus later mortality. Future research is needed to identify potential moderators of illness trajectory prior to death among patients following a COVID-19 diagnosis. CLINICAL IMPLICATIONS: Further studies are needed on this field. Limitations of our study were abscense of subgroups for different severity dementia classification, the diagnosis of COVD-19 for our data base was made based on the day an ICD code was entered on the subject’s chart, rather than physician diagnosis, patient’s symptoms starting day, or previous outside COVID-19 tests. Moreover, we didn’t account for other comorbidities, and most patients were male. DISCLOSURES: No relevant relationships by Lisa Kilpela No relevant relationships by Michael Mader No relevant relationships by Onachi Ofoma No relevant relationships by Carlos Perez Ruiz No relevant relationships by Marcos Restrepo No relevant relationships by Sandra Sanchez-Reilly

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