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1.
Applied Sciences ; 13(11):6437, 2023.
Article in English | ProQuest Central | ID: covidwho-20242320

ABSTRACT

Physical inactivity is becoming an important threat to public health in today's society. The COVID-19 pandemic has also reduced physical activity (PA) levels given all the restrictions imposed worldwide. In this work, physical activity interventions supported by mobile devices and relying on control engineering principles were proposed. The model was constructed relying on previous studies that consider a fluid analogy of Social Cognitive Theory (SCT), which is a psychological theory that describes how people acquire and maintain certain behaviors, including health-promoting behaviors, through the interplay of personal, environmental, and behavioral factors. The obtained model was validated using secondary data (collected earlier) from a real intervention with a group of male subjects in Great Britain. The present model was extended with new technology for a better understanding of behavior change interventions. This involved the use of applications, such as phone-based ecological momentary assessments, to collect behavioral data and the inclusion of simulations with logical reward conditions for reaching the behavioral threshold. A goal of 10,000 steps per day is recommended due to the significant link observed between higher daily step counts and lower mortality risk. The intervention was designed using a Model Predictive Control (MPC) algorithm configured to obtain a desired performance. The system was tested and validated using simulation scenarios that resemble different situations that may occur in a real setting.

2.
Revista Venezolana de Gerencia ; 27(8):1082, 2022.
Article in English | ProQuest Central | ID: covidwho-2206986

ABSTRACT

La pandemia de COVID-19 propició sistemáticamente una desarticulación de las clases presenciales en las instituciones educativas, constituyendo un reto para los gobiernos implementar medios e instrumentos para una educación virtual. El objetivo de este estudio fue analizar la responsabilidad social en el proceso formativo de los estudiantes en la Universidad Toribio Rodríguez de Mendoza Perú, en el contexto de la pandemia en el año 2020, se analiza su intervención a partir de sus dimensiones: enseñanza-aprendizaje, estrategias metodológicas y del manejo de instrumentos virtuales. El tipo de estudio es cuantitativo y diseño no experimental, transeccional-descriptivo, la muestra fue de 109 docentes, se aplicó un muestreo no probabilístico intencional, se utilizó un cuestionario con escalamiento tipo Likert. Los resultados demostraron que los docentes promueven la responsabilidad social universitaria en los estudiantes en tiempos de pandemia propiciando la generación de nuevos conocimientos en su desenvolvimiento en la sociedad. Concluyendo que los docentes deben promover estrategias de enseñanza innovadoras, el cambio habitual provocados por la pandemia y a valorar el manejo de instrumentos virtuales asociadas con las practicas colectivas de responsabilidad y protección social, propiciando una universidad integradora e inclusiva.Alternate :The pandemic caused by Covid-19, led to a total dismantling of face-to-face classes in educational institutions, constituting a challenge for governments to implement means and instruments for virtual education. The objective was to show social responsibility in the training process of students at the Toribio Rodríguez de Mendoza University during Covid-19, its intervention is analyzed from its dimensions: teaching-learning, methodological strategies, management of virtual instruments. The type of study is quantitative and non-experimental design, transactional-descriptive, the sample was 109 teachers, an intentional non-probabilistic sampling was applied, a Likert-type scaling questionnaire was used. The results showed that teachers promote university social responsibility in students in times of pandemic, promoting the generation of new knowledge in their development in society. Concluding that teachers must promote innovative teaching strategies, the usual change caused by the pandemic and value the management of virtual instruments associated with collective practices of responsibility and social protection, promoting an inclusive and inclusive university.

3.
Revista Ibérica de Sistemas e Tecnologias de Informação ; - (E51):142-156, 2022.
Article in Spanish | ProQuest Central | ID: covidwho-2112111

ABSTRACT

Palabras-clave: metodologías activas, enseñanza;aprendizaje;COVID-19 : The impact of the Covid-19 pandemic has led to a "social distancing" in academic institutions of higher education and the need to implement contingency plans for the continuity of their activities, forcing teaching supported by teleeducation;outlining new teaching strategies in engineering. The objective of the research was to make a bibliographic review analyzing the active methodologies in virtual teaching-learning environments used by teachers. The methodology was focused on a systematic review (SR), considering 105 articles published between the years 2015-2022 related to scientific literature articles with active methodologies in virtual environments identified in different databases. Keywords: active methodologies;teaching;learning;COVID-19 1.Introducción Debido al impacto de la pandemia por Covid-19, las instituciones académicas de enseñanza superior tienen la necesidad de implementar planes de contingencia para la continuidad de sus actividades dentro del proceso de enseñanza.

4.
World J Clin Cases ; 10(4): 1296-1310, 2022 Feb 06.
Article in English | MEDLINE | ID: covidwho-1689753

ABSTRACT

BACKGROUND: Research concerning postoperative outcomes of confirmed coronavirus disease 2019 (COVID-19) patients revealed unfavorable postoperative results with increased morbidity, pulmonary complications and mortality. Case reports have suggested that COVID-19 is associated with more aggressive presentation of acute cholecystitis. The aim of the present study is to describe the perioperative assessment and postoperative outcomes of ten patients with confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection with concomitant acute cholecystitis who underwent cholecystectomy. CASE SUMMARY: We report a total of 10 SARS-CoV-2 positive patients with concomitant acute cholecystitis that underwent cholecystectomy. Six patients were males, the mean age was 47.1 years. Nine patients had moderate acute cholecystitis, and one patient had severe acute cholecystitis. All patients were treated with urgent/early laparoscopic cholecystectomy. Regarding the Parkland grading scale, two patients received a Parkland grade of 3, two patients received a Parkland grade of 4, and six patients received a Parkland grade of 5. Eight patients required a bail-out procedure. Four patients developed biliary leakage and required endoscopic retrograde cholangiopancreatography with biliary sphincterotomy. After surgery, five patients developed acute respiratory distress syndrome (ARDS) and required intensive care unit (ICU) admission. One patient died after cholecystectomy due to ARDS complications. The mean total length of stay (LOS) was 18.2 d. The histopathology demonstrated transmural necrosis (n = 5), vessel obliteration with ischemia (n = 3), perforation (n = 3), and acute peritonitis (n = 10). CONCLUSION: COVID-19 patients with acute cholecystitis had difficult cholecystectomies, high rates of ICU admission, and a prolonged LOS.

6.
Politica y Cultura ; - (55):121-148, 2021.
Article in Spanish | ProQuest Central | ID: covidwho-1303110

ABSTRACT

Se presentan los resultados obtenidos en la investigación realizada durante la pandemia producida por el virus SARS-CoV-2 o covid-19, donde se vio afectado el sector estudiantil. Esta investigación se enfoca en experiencias y vivencias resultantes del confinamiento y las clases en línea, así como las dificultades y aciertos que se presentan en la implementación de este repentino modelo de enseñanza en estudiantes de nivel medio y superior. Los resultados muestran en general obstáculos y restricciones que desfavorecen la educación en México.Alternate abstract:This article reports the results obtained in the research carried out during the pandemic produced by the SARS-CoV-2 or covid-19 virus, where the student sector was affected. This research focuses on the feelings and emotions resulting from confinement and online classes, as well as the difficulties and successes that arise in the implementation of this sudden teaching model in middle and upper-level students. Resulting in mostly obstacles and restrictions that disadvantage education in Mexico.

8.
PLoS One ; 16(3): e0249128, 2021.
Article in English | MEDLINE | ID: covidwho-1148251

ABSTRACT

INTRODUCTION: The analysis of heart rate variability (HRV) has proven to be an important tool for the management of autonomous nerve system in both surgical and critically ill patients. We conducted this study to show the different spectral frequency and time domain parameters of HRV as a prospective predictor for critically ill patients, and in particular for COVID-19 patients who are on mechanical ventilation. The hypothesis is that most severely ill COVID-19 patients have a depletion of the sympathetic nervous system and a predominance of parasympathetic activity reflecting the remaining compensatory anti-inflammatory response. MATERIALS AND METHODS: A single-center, prospective, observational pilot study which included COVID-19 patients admitted to the Surgical Intensive Care Unit was conducted. The normalized high-frequency component (HFnu), i.e. ANIm, and the standard deviation of RR intervals (SDNN), i.e. Energy, were recorded using the analgesia nociception index monitor (ANI). To estimate the severity and mortality we used the SOFA score and the date of discharge or date of death. RESULTS: A total of fourteen patients were finally included in the study. ANIm were higher in the non-survivor group (p = 0.003) and were correlated with higher IL-6 levels (p = 0.020). Energy was inversely correlated with SOFA (p = 0.039) and fewer survival days (p = 0.046). A limit value at 80 of ANIm, predicted mortalities with a sensitivity of 100% and specificity of 85.7%. In the case of Energy, a limit value of 0.41 ms predicted mortality with all predictive values of 71.4%. CONCLUSION: A low autonomic nervous system activity, i.e. low SDNN or Energy, and a predominance of the parasympathetic system, i.e. low HFnu or ANIm, due to the sympathetic depletion in COVID-19 patients are associated with a worse prognosis, higher mortality, and higher IL-6 levels.


Subject(s)
COVID-19/complications , COVID-19/mortality , Heart Rate/physiology , Adult , Autonomic Nervous System , COVID-19/epidemiology , Critical Illness , Female , Humans , Intensive Care Units , Male , Middle Aged , Monitoring, Physiologic , Nociception/physiology , Pain , Pain Management , Pain Measurement/methods , Pilot Projects , Prognosis , Prospective Studies , SARS-CoV-2/pathogenicity , Severity of Illness Index
9.
Curr Opin Virol ; 44: 97-111, 2020 10.
Article in English | MEDLINE | ID: covidwho-695561

ABSTRACT

Emerging viral diseases pose a major threat to public health worldwide. Nearly all emerging viruses, including Ebola, Dengue, Nipah, West Nile, Zika, and coronaviruses (including SARS-Cov2, the causative agent of the current COVID-19 pandemic), have zoonotic origins, indicating that animal-to-human transmission constitutes a primary mode of acquisition of novel infectious diseases. Why these viruses can cause profound pathologies in humans, while natural reservoir hosts often show little evidence of disease is not completely understood. Differences in the host immune response, especially within the innate compartment, have been suggested to be involved in this divergence. Natural killer (NK) cells are innate lymphocytes that play a critical role in the early antiviral response, secreting effector cytokines and clearing infected cells. In this review, we will discuss the mechanisms through which NK cells interact with viruses, their contribution towards maintaining equilibrium between the virus and its natural host, and their role in disease progression in humans and other non-natural hosts.


Subject(s)
Communicable Diseases, Emerging/immunology , Communicable Diseases, Emerging/transmission , Killer Cells, Natural/immunology , Viral Zoonoses/immunology , Viral Zoonoses/transmission , Animals , COVID-19/immunology , COVID-19/transmission , Chiroptera/virology , Haplorhini/virology , Humans , Rodentia/virology , Severe acute respiratory syndrome-related coronavirus/immunology , SARS-CoV-2/immunology , Severe Acute Respiratory Syndrome/immunology , Severe Acute Respiratory Syndrome/transmission
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