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Journal of Pharmaceutical Research International ; 33(44B):504-516, 2021.
Article in English | Web of Science | ID: covidwho-1481203


Despite the threat of coronavirus infection, the Siddha system of medicine, India's traditional medicine, plays an important role in southern India, particularly in Tamilnadu. It contributed considerably not only in the first wave of Covid-19, but also in the second wave. The Government of Tamilnadu developed Siddha COVID-19 treatment centers for asymptomatic, mild, and moderate COVID-19 positive patients in 2020. The TPEC COVID Care Centre initiated at Vellore also one of the Centers that can be managed by Siddha medicines and Siddhar's Yogam. As of July 14, 2021, about 4525 COVID positive patients had been treated with Siddha integrated treatment at Vellore alone in the first and second waves. Kaba Sura Kudineer, Thalisathy Vadagam, Amukkara Chooranam Mathirai, Bramanandha Bairavam Mathirai, and Adathodai Manapagu are indeed the five Siddha classical preparations used to manage the symptoms of COVID-19 positive patients at TPEC COVID Care Centre in Vellore. This Siddha medical practice is effective in conditions of symptoms and helps in the reduction of clinical outcomes. A pilot study at the same site confirmed the Siddha classical preparation's safety and effectiveness. A feedback analysis study performed at the same center also revealed that the above-mentioned Siddha classical preparations are beneficial in symptomatic treatment without causing any side effects. The medicines utilized in this study are typically proposed in other COVID care centers also in Tamilnadu. This review attempted to analyze the preclinical and clinical efficacy of Siddha Classical medicines used at that Centre for the management of COVID-19.

Journal of Natural Remedies ; 21(3):259-263, 2021.
Article in English | Scopus | ID: covidwho-1335478


Siddha Clinical Research Unit (SCRU) Tirupati, working under the Central Council for Research in Siddha (CCRS), Ministry of AYUSH, Govt. of India, conducted a National Web conference titled “Integrated Siddha Approach in Clinical Practice and Research on COVID-19 Pandemic (ISACC)” on 23rd Dec 2020, as a part of the fourth Pre-Siddha Day observance. Totally, 256 participants from Siddha colleges and various institutes of CCRS attended the Web conference and 9 eminent Speakers share their knowledge at the conference. The Technical session was separated by three panels, (i)Siddha Standalone and Integrative Clinical trials on COVID-19, (ii)Siddha Preventive and Prophylactic Measures on COVID-19, (iii)Experiences in Siddha Integrative Clinical Practice on COVID-19. The take home message of the conference insisted upon the three facts-the need for more clinical trials, need for increased experience sharing platforms for Siddha medical system and finally that Siddha standalone as well as integration for COVID-19 management gave significant outcome in both preventive and promotive healthcare. Central Council for Research in Siddha (CCRS), Ministry of AYUSH, Govt. of India and Directorate of Indian Medicine and Homeopathy (DIMAndH), Government of Tamil Nadu, contributed a lot in Research and services in COVID-19 pandemic. © 2021, Informatics Publishing Limited. All rights reserved.

Journal of Natural Remedies ; 21(2):109-123, 2021.
Article in English | Scopus | ID: covidwho-1219852


Respiratory Tract Infections (RTIs) are the most common, and potentially most severe, of infections treated by health care practitioners. Lower RTIs along with influenza, are the most common cause of death by infection. The fatality risk is doubled if the person is with other morbid conditions or in extremes of age. These seasonal respiratory infections caused by viruses are of more concern as their spread is very vast than we imagine. COVID-19 (corona virus disease 2019) is such a pandemic respiratory illness caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), a strain of Corona virus. The emerging anti-microbial resistance and easy spread of respiratory pathogens has also increased the challenge for appropriate management of RTI like COVID-19. Drugs with anti-viral property and potency to prevent the co-morbidity stand are the need of the hour. This review article includes information on preclinical studies and clinical studies to add a scientific validation to formulations that are commonly used in Siddha system of Medicine. The ingredients of the Siddha drugs possessing anti-viral property and immune-modulatory effect particularly against respiratory pathogens are elaborated. Evidence of anti-viral property has been made out to the light for further clinical trials. © 2021, Informatics Publishing Limited. All rights reserved.