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Clinical Research in Cardiology ; 110(2):292-301, 2021.
Article | WHO COVID | ID: covidwho-1064474


AIMS: During the COVID-19 pandemic, hospital admissions for cardiac care have declined However, effects on mortality are unclear Thus, we sought to evaluate the impact of the lockdown period in central Germany on overall and cardiovascular deaths Simultaneously we looked at catheterization activities in the same region METHODS AND RESULTS: Data from 22 of 24 public health-authorities in central Germany were aggregated during the pandemic related lockdown period and compared to the same time period in 2019 Information on the total number of deaths and causes of death, including cardiovascular mortality, were collected Additionally, we compared rates of hospitalization (n = 5178) for chronic coronary syndrome (CCS), acute coronary syndrome (ACS), and out of hospital cardiac arrest (OHCA) in 26 hospitals in this area Data on 5,984 deaths occurring between March 23, 2020 and April 26, 2020 were evaluated In comparison to the reference non-pandemic period in 2019 (deaths: n = 5832), there was a non-significant increase in all-cause mortality of 2 6% [incidence rate ratio (IRR) 1 03, 95% confidence interval (CI) 0 99-1 06;p = 0 16] Cardiovascular and cardiac mortality increased significantly by 7 6% (IRR 1 08, 95%-CI 1 01-1 14;p = 0 02) and by 11 8% (IRR 1 12, 95%-CI 1 05-1 19;p < 0 001), respectively During the same period, our data revealed a drop in cardiac catherization procedures CONCLUSION: During the COVID-19-related lockdown a significant increase in cardiovascular mortality was observed in central Germany, whereas catherization activities were reduced The mechanisms underlying both of these observations should be investigated further in order to better understand the effects of a pandemic-related lockdown and social-distancing restrictions on cardiovascular care and mortality