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J Med Toxicol ; 17(4): 333-362, 2021 10.
Article in English | MEDLINE | ID: covidwho-1415107


The Toxicology Investigators Consortium (ToxIC) Registry was established by the American College of Medical Toxicology in 2010. The registry collects data from participating sites with the agreement that all bedside and telehealth medical toxicology consultation will be entered. This eleventh annual report summarizes the Registry's 2020 data and activity with its additional 6668 cases. Cases were identified for inclusion in this report by a query of the ToxIC database for any case entered from January 1 to December 31, 2020. Detailed data was collected from these cases and aggregated to provide information which included demographics, reason for medical toxicology evaluation, agent and agent class, clinical signs and symptoms, treatments and antidotes administered, mortality, and whether life support was withdrawn. Gender distribution included 50.6% cases in females, 48.4% in males, and 1.0% identifying as transgender. Non-opioid analgesics were the most commonly reported agent class, followed by opioid and antidepressant classes. Acetaminophen was once again the most common agent reported. There were 80 fatalities, comprising 1.2% of all registry cases. Major trends in demographics and exposure characteristics remained similar to past years' reports. Sub-analyses were conducted to describe race and ethnicity demographics and exposures in the registry, telemedicine encounters, and cases related to the COVID-19 pandemic.

Congresses as Topic , Hazardous Substances/toxicity , Poisoning/diagnosis , Poisoning/therapy , Registries/statistics & numerical data , Research Report , Toxicology/statistics & numerical data , Adult , Aged , Aged, 80 and over , COVID-19 , Canada , Female , Humans , Israel , Male , Middle Aged , Pandemics/statistics & numerical data , SARS-CoV-2 , Thailand , United States